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Serum vitamin D concentration and prostate cancer risk: a nested case-control study. Ahn J, Peters U, Albanes D, Purdue MP, Abnet CC, Chatterjee N, Horst RL, Hollis BW, Huang WY, Shikany JM, Hayes RB; Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Project Team. J Natl Cancer Inst. 2008 Jun 4;100(11):796-804. Epub 2008 May 27. PMID: 18505967 doi:10.1093/jnci/djn152 CONCLUSION: The findings of this large prospective study do not support the hypothesis that vitamin D is associated with decreased risk of prostate cancer; indeed, higher circulating 25(OH)D concentrations may be associated with increased risk of aggressive disease. In summary, results from this large prospective study of men who underwent standardized prostate cancer screening in the context of a screening trial do not support the hypothesis that higher serum vitamin D status is associated with decreased risk of prostate cancer. The study showed no association of vitamin D level with nonaggressive disease; however, it raises the possibility that higher vitamin D level may be associated with increased risks for aggressive disease, although a clear monotonic dose-response relationship was lacking. Along with recent reports of adverse associations for higher vitamin D status and risk of pancreatic (32) and esophageal (33,34) cancer, caution should be taken in recommending high doses of vitamin D or sunlight exposure to the general public for prostate cancer prevention. Future analyses are warranted to confirm these results and to further clarify the effects of vitamin D on aggressive prostate cancer.

"LOS ANGELES (September 29, 2009) -- A simple, non-invasive test appears to be an effective screening tool for identifying patients with silent heart disease who are at risk for a heart attack or sudden death. Coronary artery calcium scans can be done without triggering excessive additional testing and costs, according to the multi-center EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) study, led by investigators at the Cedars-Sinai Heart Institute. The findings appear in today's issue of the findings appear in today's issue of the Journal of the American College of Cardiology."

"New research shows a long-term benefit in screening people for CRP, a marker for inflammation, even if they have normal levels of bad cholesterol, because of increased long-term risk for heart attack, stroke and death. These findings, which will be published online today in the Journal of the American College of Cardiology (JACC), demonstrate that a very simple screening, age plus CRP, can identify individuals who may benefit from statin therapy. "This study builds on results from the landmark JUPITER trial, which showed that statins can prevent heart disease in people with normal LDL-c, or bad cholesterol, and an increased level of CRP," said Dr. Christie Ballantyne, director of the Center for Cardiovascular Disease Prevention at the Methodist DeBakey Heart & Vascular Center and last author on the study. "We have demonstrated that the cardiovascular disease event rates persist over time, validating that the risks identified in the JUPITER trial persist for nearly seven year"

In a pilot test, the program helped children reduce body mass index, achieve more muscle mass, improve their health-related quality of life, reduce screen time, and increase levels of physical activity.

Serum levels of vitamin D metabolites and breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Freedman DM, Chang SC, Falk RT, Purdue MP, Huang WY, McCarty CA, Hollis BW, Graubard BI, Berg CD, Ziegler RG. Cancer Epidemiol Biomarkers Prev. 2008 Apr;17(4):889-94. Epub 2008 Apr 1. PMID: 18381472 doi: 10.1158/1055-9965.EPI-07-2594 In this prospective study of postmenopausal women, we did not observe an inverse association between circulating 25(OH)D or 1,25(OH)2D and breast cancer risk, although we cannot exclude an association in younger women or with long-term or earlier exposure

Serum vitamin D and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian screening trial. Stolzenberg-Solomon RZ, Hayes RB, Horst RL, Anderson KE, Hollis BW, Silverman DT. Cancer Res. 2009 Feb 15;69(4):1439-47. Epub 2009 Feb 10. PMID: 19208842

Charity is when those who have too much give a bit to those who have too little. These affluent givers tell themselves (and others) that their hearts bleed for you. At the same time, they are unable to resist telegraphing to you (and others) that they're intrinsically superior. Clearly, they're not obligated to help you. Your neediness is...well...yours. Your misfortune is not their doing, after all. Yet, they're compelled to be charitable; the impulse arises out of simple inborn nobility. But you are quite surely obligated to them. Being quite good and generous, your benefactors have, once again, won the game of "right living." You must be grateful that your deprivation even registered on their radar screen. In fact, you are really quite fortunate, quite lucky. Although I don't think this luck was what the good lord Jesus meant by "the meek shall inherit the earth."

Charity is when those who have too much give a bit to those who have too little. These affluent givers tell themselves (and others) that their hearts bleed for you. At the same time, they are unable to resist telegraphing to you (and others) that they're intrinsically superior. Clearly, they're not obligated to help you. Your neediness is...well...yours. Your misfortune is not their doing, after all. Yet, they're compelled to be charitable; the impulse arises out of simple inborn nobility. But you are quite surely obligated to them. Being quite good and generous, your benefactors have, once again, won the game of "right living." You must be grateful that your deprivation even registered on their radar screen. In fact, you are really quite fortunate, quite lucky. Although I don't think this luck was what the good lord Jesus meant by "the meek shall inherit the earth."

Not enough vitamin D: health consequences for Canadians. Schwalfenberg G. Can Fam Physician. 2007 May;53(5):841-54. Review PMID: 17872747 Conclusion Low levels of VTD are considered a major public health problem in Canada, especially during the winter. Those with risk factors should be screened for low 25(OH)D levels and repletion therapy instituted if needed. Researchers have estimated that the oral dose of vitamin D3 to attain and maintain 25(OH)D levels >80 nmol/L is 2200 IU/d if baseline levels are 20 to 40 nmol/L, 1800 IU/d if levels are 40 to 60 nmol/L, and 1160 IU/d if levels are between 60 and 80 nmol/L.64 We need to ensure that patients have healthy blood levels of 25(OH)D to prevent levels of parathyroid hormone from rising and to maximize absorption of calcium, magnesium, and phosphate. Positive effects on bone are marginal at best unless patients consume at least 800 IU/d of VTD. The emerging and exciting role of the VTD receptor and the actions of VTD in maintaining health in other cell types have become more apparent during the last decade.

A New Zealand study has found that South Asian women with insulin resistance improved markedly after taking vitamin D supplements Nutrition researcher Pamela von Hurst of the Institute of Food, Nutrition and Human Health at Albany, said while diet and exercise played a major part in the onset of type-2 diabetes, her findings reinforced the importance of vitamin D from the sun and supplements to prevent type-2 diabetes. Initial screening of 235 Auckland women from India, Pakistan and Sri Lanka aged 20 and older, revealed 47 per cent were insulin deficient and 84 per cent were vitamin D deficient. The 81 recruited for the study were split into two groups for a randomised controlled trial and given a vitamin D supplement or placebo. As well as an improvement in insulin resistance among those who took vitamin D for six months, Ms Von Hurst said post-menopausal women in the study also showed a reduced rate of bone breakdown.

Vitamin D and cardiovascular disease risk. Michos ED, Melamed ML. Curr Opin Clin Nutr Metab Care. 2008 Jan;11(1):7-12. Review. PMID: 18090651 doi: 10.1097/MCO.0b013e3282f2f4dd Summary: Vitamin D deficiency is easy to screen for and easy to treat with supplementation. Further larger observational studies and randomized clinical trials are, however, needed to determine whether vitamin D supplementation could have any potential benefit in reducing future cardiovascular disease events and mortality risk.

The Baxter SIGMA Spectrum Infusion System is redefining smart technology with Second Generation software to help prevent pump-related medication errors. The SIGMA Spectrum Infusion System provides multiple error prevention systems along with bi-directional wireless communication and comprehensive log analysis software to create CQI reports. SIGMA Spectrum pump provides rapid, intuitive work-flow using a bright, easy to read color display and on-board digital help screens. SIGMA Spectrum pump also provides economic value by utilizing Baxter's standard IV administration sets.

The Baxter SIGMA Spectrum Infusion System is redefining smart technology with Second Generation software to help prevent pump-related medication errors. The SIGMA Spectrum Infusion System provides multiple error prevention systems along with bi-directional wireless communication and comprehensive log analysis software to create CQI reports. SIGMA Spectrum pump provides rapid, intuitive work-flow using a bright, easy to read color display and on-board digital help screens.

The Baxter SIGMA Spectrum Infusion System is redefining smart technology with Second Generation software to help prevent pump-related medication errors. The SIGMA Spectrum Infusion System provides multiple error prevention systems along with bi-directional wireless communication and comprehensive log analysis software to create CQI reports. SIGMA Spectrum pump provides rapid, intuitive work-flow using a bright, easy to read color display and on-board digital help screens. SIGMA Spectrum pump also provides economic value by utilizing Baxter's standard IV administration sets *Refurbished *1-Year Warranty