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Matti Narkia

Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disea... - 0 views

www.thorne.com/...223.pdf

2003 August study review Th1_Th2 balance Th:Th2 Th1 Th2 immune function immunity hypothesis limitations implications health medline altmed cam nutrition plant sterols phytosterols melatonin probiotics progesterone selenium zinc thorne cancer

shared by Matti Narkia on 15 Apr 09 - Cached
  • Matti Narkia on 15 Apr 09
     
    Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Kidd P. Altern Med Rev. 2003 Aug;8(3):223-46. Review. PMID: 12946237 Th1 pathways typically produce activation of cytotoxic T lymphocytes (Tc), NK cells, macrophages, and monocytes, all of which can attack cancer cells and generally defend against tumors. 55 IFN-gamma and other Th1 cytokines are typically lower in advanced cancer patients, while the Th2 marker IL-4 can be higher or unchanged.56 Nodules of non-small cell lung cancer freshly removed from patients expressed a marked imbalance toward Th2, as did biopsy samples from basal cell carcinoma.57 In prostate cancer patients IL-2 was low (Th1) and IL-10 high.58 IL-10 is a confirmed Th1-suppressive cytokine, and heightened IL-10 is a common factor in cancer.55 IL-10 has a variety of suppressive effects that include inhibiting Th1 cytokine production, down-regulating APC and NK cell function, and lowering overall T-cell proliferation.57 Especially under the influence of IL-4 (Th2), tumor cells apparently up-regulate IL-10 that suppresses nearby killer cells. Tumor-derived IL-10 has been documented in lymphoma, ovarian carcinoma, melanoma, neuroblastoma, and renal cell and colon carcinoma.57 IL-12 is another cytokine that can be up-regulated by Th1 activity and inhibited by Th2.59 A low IL-12/IL-10 ratio was found in cervical cancer patients.55 Recent clinical studies suggest elevated IL-10 is predictive of a poor prognosis. 57 With both IL-4 and IL-10 being proven inhibitors of Th1 and promoters of Th2 activity, the recognized capability of cancerous tissue to suppress immunity is readily rationalized.
Matti Narkia

Sulbutiamine - Wikipedia, the free encyclopedia - 0 views

en.wikipedia.org/...Sulbutiamine

sulbutiamine info information reference wikipedia vitamin_B1 thiamine precursor asthenia chronic fatigue chronic_fatigue memory cognition schizophrenia nootropic.erectile_dysfunction ED impotence nutrition supplement dietary nutritional

shared by Matti Narkia on 28 Mar 09 - Cached
  • Matti Narkia on 28 Mar 09
     
    Sulbutiamine (brand name: Arcalion) is a precursor to thiamine (i.e., vitamin B1). As a dimer of two structurally modified thiamine residues, sulbutiamine retains many of the features of thiamine. However, the thiazole rings are open, the alcohol groups are esterified, and a disulfide bridge connects the two thiamine analogues. Sulbutiamine is indicated for the treatment of asthenia.[1] Its ability to reduce fatigue is also considered desirable by athletes, and it is available for over-the-counter sale as a nutritional supplement. In one study of chronic fatigue patients, sulbutiamine did not demonstrate sustained benefits over the placebo, which raises doubts about its clinical efficacy.[2] However, the authors of that study suggest that additional research is needed to evalulate the potential usefulness of sulbutiamine in the treatment of chronic fatigue. Sulbutiamine may be beneficial for cognition. Indeed, the demonstrated ability of sulbutiamine to improve memory in rats[3] and patients of schizophrenia[3] suggests that it is a nootropic. Recent research also shows support for the use of sulbutiamine in the treatment of erectile dysfunction
Matti Narkia

Sham vs. Wham: The Health Insider: Omega 3 In the News Again - Lower Advanced Prostate ... - 0 views

shamvswham.blogspot.com/...news-again-lower-advanced.html

2009 March shamvswham blog_article news epidemiological case-control humans men prostate cancer prostate_cancer advanced agressive risk cancer_risk omega-3 PUFA risk_reduction long-chain EPA DHA COX-2 gene genetics nutrition inflammation PCa

shared by Matti Narkia on 28 Mar 09 - Cached
  • Matti Narkia on 28 Mar 09
     
    new (March 24th) report in Clinical Cancer Research, a journal of the American Association for Cancer Research, shows that Omega-3 fatty acids appear protective against advanced prostate cancer. Dr. John S. Witte, Ph.D., professor of epidemiology and biostatistics at the University of California San Francisco, says that previous research has shown protection against prostate cancer, but that this is one of the first studies to show protection against advanced prostate cancer.
Matti Narkia

Mushrooms are top source for one antioxidant, ergothioneine - 0 views

www.medicalnewstoday.com/...29988.php

2005 September medicalnewstoday news ergothioneine L-ergothioneine antioxidant antioxidants mushrooms white button mushroom white_button_mushroom wheat germ wheat_germ germs chicken liver chicken_liver nutrition shiitake oyster oyster_mushroom maitake

shared by Matti Narkia on 30 May 09 - Cached
  • Matti Narkia on 30 May 09
     
    Using a new, more sensitive-testing approach they developed for fungi, Penn State food scientists have found that mushrooms are a better natural source of the antioxidant ergothioneine than either of the two dietary sources previously believed to be best. The researchers found that white button mushrooms, the most commonly consumed kind in the U.S., have about 12 times more of the antioxidant than wheat germ and 4 times more than chicken liver, the previous top-rated ergothioneine sources based on available data. Until the Penn State researchers developed their testing approach, known as an assay, there was no method employing the most sensitive modern instrumentation and analytical techniques to quantify the amount of ergothioneine in fungi. The researchers say that their assay can be used for other plants, too, not just mushrooms.
Dr. John Bureau DC

Face Protection Effective In Preventing The Spread Of Influenza, Study Suggests - 0 views

www.sciencedaily.com/...090520161332.htm

flu influenza prevention mask

shared by Dr. John Bureau DC on 25 May 09 - Cached
  • ScienceDaily (May 22, 2009) — A new article in the journal Risk Analysis assessed various ways in which aerosol transmission of the flu, a central mode of diffusion which involves breathing droplets in the air, can be reduced. Results show that face protection is a key infection control measure for influenza and can thus affect how people should try to protect themselves from the swine flu. See also: Health & Medicine Cold and Flu Influenza Bird Flu Plants & Animals Bird Flu Research Virology Developmental Biology Reference Flu vaccine Influenza pandemic Transmission (medicine) Avian flu Lawrence M. Wein, Ph.D., and Michael P. Atkinson of Stanford University constructed a mathematical model of aerosol transmission of the flu to explore infection control measures in the home. Their model predicted that the use of face protection including N95 respirators (these fit tight around the face and are often worn by construction workers) and surgical masks (these fit looser around the face and are often worn by dental hygienists) are effective in preventing the flu. The filters in surgical masks keep out 98 percent of the virus. Also, only 30 percent of the benefits of the respirators and masks are achieved if they are used only after an infected person develops symptoms. "Our research aids in the understanding of the efficacy of infection control measures for influenza, and provides a framework about the routes of transmission," the authors conclude. This timely article has the potential to impact current efforts and recommendations to control the so-called swine flu by international, national and local governments in perspective. This study is published in the journal Risk Analysis.
  • Dr. John Bureau DC on 25 May 09
     
    for more articles, see blog: drjohndc.tumblr.com
  • Dr. John Bureau DC on 25 May 09
     
    ScienceDaily (May 22, 2009) - A new article in the journal Risk Analysis assessed various ways in which aerosol transmission of the flu, a central mode of diffusion which involves breathing droplets in the air, can be reduced. Results show that face protection is a key infection control measure for influenza and can thus affect how people should try to protect themselves from the swine flu. Lawrence M. Wein, Ph.D., and Michael P. Atkinson of Stanford University constructed a mathematical model of aerosol transmission of the flu to explore infection control measures in the home. Their model predicted that the use of face protection including N95 respirators (these fit tight around the face and are often worn by construction workers) and surgical masks (these fit looser around the face and are often worn by dental hygienists) are effective in preventing the flu. The filters in surgical masks keep out 98 percent of the virus. Also, only 30 percent of the benefits of the respirators and masks are achieved if they are used only after an infected person develops symptoms. "Our research aids in the understanding of the efficacy of infection control measures for influenza, and provides a framework about the routes of transmission," the authors conclude. This timely article has the potential to impact current efforts and recommendations to control the so-called swine flu by international, national and local governments in perspective. This study is published in the journal Risk Analysis.
Matti Narkia

Benfotiamine nothing but "Snake Oil" - 0 views

www.news-medical.net/?id=39210

2008 June news benfotiamine bioavailability brain lipid-soluble vitamin_B1 hiamine precursors precursor sulbutiamine absorption nutrition medline supplement supplementation snake oil snake_oil

shared by Matti Narkia on 28 Mar 09 - Cached
  • Matti Narkia on 28 Mar 09
     
    A popular vitamin supplement is being advertised with claims that are demonstrably untrue, as revealed by research published in the open access journal BMC Pharmacology. Benfotiamine is a synthetic derivative of thiamine (vitamin B1). It is marketed heavily as a dietary supplement using a selection of unsubstantiated, 'not-quite-medical' claims that tend to characterize this field. A large part of this campaign has been built around the belief that benfotiamine is lipid-soluble and, therefore, more physiologically active. Scientific research led by Dr Lucien Bettendorff of the Center for Cellular and Molecular Neurobiology at the University of Liège, Belgium, has entirely disproved these claims.
Matti Narkia

CIDRAP >> Researchers find antibody that fights H5N1, seasonal flu strains - 0 views

www.cidrap.umn.edu/...feb2309monoclonal-br.html

2009 February news influenza antibody seasonal pandemic avian H5N1 vaccine passive immunotherap passive_immunotherapy medcine Dana-Farber Dana-Farber_Cancer_Center

shared by Matti Narkia on 27 Feb 09 - Cached
  • Matti Narkia on 27 Feb 09
     
    Feb 23, 2009 (CIDRAP News) - In a development that could create new tools to prevent and treat seasonal and pandemic influenza, researchers have identified and tested human monoclonal antibodies (mAbs) that can neutralize influenza A viruses, including lethal H5N1 avian influenza.\n\nThe findings raise hopes for a universal flu vaccine and shed light on new options for preventing and treating influenza infections, researchers from Dana-Farber Cancer Center, Burnham Institute for Medical Research, and the US Centers for Disease Control and Prevention (CDC) reported yesterday in an early online edition of Nature Structural and Molecular Biology. The study was supported by a grant from the National Institute of Allergy and Infectious Diseases (NIAID).
Dr. John Bureau DC

Medical News: Heart Patients Should Walk Often, Walk Far - in Primary Care, Exercise & ... - 0 views

www.medpagetoday.com/...14185

heart exercise walking

shared by Dr. John Bureau DC on 14 May 09 - Cached
  • LITTLE FALLS, N.J., May 13 -- Exercise regimens that burn more calories over less-intense periods of exercise can increase weight loss and reduce cardiovascular risk factors better than standard cardiac rehabilitation programs, researchers have found. Action Points  Explain that walking more at a slower pace improved weight loss and cardiac risk factors better than standard cardiac rehabilitation programs.Note that current cardiac rehabilitation guidelines were written when deconditioning after lengthy hospital stays was common, which is no longer the case. In a randomized trial, overweight patients who exercised more but with less intensity lost twice as much weight as those on typical cardiac rehab regimens and had greater reductions in markers of metabolic syndrome, according to Philip A. Ades, M.D., of the University of Vermont, and colleagues. "High-calorie-expenditure exercise is superior to standard cardiac rehabilitation exercise in accomplishing weight loss and favorably altering cardiometabolic risk factors, particularly insulin resistance, in overweight patients with coronary heart disease," the researchers reported online in Circulation: Journal of the American Heart Association.
  • Dr. John Bureau DC on 14 May 09
     
    LITTLE FALLS, N.J., May 13 -- Exercise regimens that burn more calories over less-intense periods of exercise can increase weight loss and reduce cardiovascular risk factors better than standard cardiac rehabilitation programs, researchers have found. In a randomized trial, overweight patients who exercised more but with less intensity lost twice as much weight as those on typical cardiac rehab regimens and had greater reductions in markers of metabolic syndrome, according to Philip A. Ades, M.D., of the University of Vermont, and colleagues. "High-calorie-expenditure exercise is superior to standard cardiac rehabilitation exercise in accomplishing weight loss and favorably altering cardiometabolic risk factors, particularly insulin resistance, in overweight patients with coronary heart disease," the researchers reported online in Circulation: Journal of the American Heart Association.
Matti Narkia

Traffic Triples Heart Attack Risk - WebMD - 0 views

www.webmd.com/...ffic-triples-heart-attack-risk

2009 March WebMD news traffic air pollution air_pollution exhaust fumes exhaust_fumes CVD CHD heart attack heart_attack MI myocardial_infarction risk health

shared by Matti Narkia on 15 Mar 09 - Cached
  • Matti Narkia on 15 Mar 09
     
    March 13, 2009 -- Whether you drive, take the bus, or bicycle, being in heavy traffic triples your risk of heart attack within one hour. Air pollution from car fumes is the likely culprit, suggest Annette Peters, PhD, and colleagues at the Institute of Epidemiology, Helmholtz Center, Munich, Germany. In a previous study, Peters and colleagues found that a sizeable proportion of heart attacks -- about 8% -- could be attributed to being in traffic. To follow up, the researchers interviewed 1,454 people who survived heart attacks. In the hour before their heart attack, many of the survivors had been in heavy traffic. Analysis of the data showed that these heart-attack-vulnerable people were 3.2 times more likely to suffer a heart attack if they'd been in heavy traffic in the previous hour.
Matti Narkia

Vitamin K2 and coronary plaque - Wellsphere - 0 views

stanford.wellsphere.com/...239840

2008 August blog_article vitamin K2 vitamin_K2 coronary plaque CHD CVD osteoporosis cheese natto supplementation supplements

shared by Matti Narkia on 25 Feb 09 - Cached
  • Matti Narkia on 25 Feb 09
     
    The vitamin K2 story, though still preliminary, is becoming increasingly interesting from the perspective of CT heart score reduction. The origin of this concept came from some unexpected observations. One, the observation that osteoporosis (lack of bone calcium that leads to fractures) arises from deficiency of vitamin K2. Two, deficiency of K2 leads to unrestrained calcium deposition in animal models, leading to heart attack in just weeks.
Matti Narkia

Low vitamin D linked to death from heart and circulation problems | - 0 views

www.guardian.co.uk/...ath-from-heart-and-circulation

2008 June Guardian news vitamin D vitamin_D vitamin_D_deficiency deficiency inadequacy low level low_level: heart circulation problems death mortality CVD nutrition risk chest pain chest_pain atherosclerosis

shared by Matti Narkia on 25 Feb 09 - Cached
  • Matti Narkia on 25 Feb 09
     
    Scientists have long known that a lack of vitamin D can weaken our bones. A new study shows that low levels of this nutrient may also be linked to a higher chance of dying early from heart and circulation problems, as well as other causes.
Matti Narkia

Sleep 'influences diabetes risk' - BBC NEWS | Health - 0 views

news.bbc.co.uk/...7936569.stm

2009 March BBC news sleep duration sleep_duration type 2 diabetes type_2_diabetes type_2 diabetes risk type 2 health

shared by Matti Narkia on 12 Mar 09 - Cached
  • Matti Narkia on 12 Mar 09
     
    Burning the candle at both ends during the working week could raise a person's risk of developing type 2 diabetes, New York researchers say. People who slept fewer than six hours a night were more likely to develop a condition that precedes diabetes than those sleeping for longer, they found. They said the study supported mounting evidence that cutting back on sleep can have a profound impact on health.
Matti Narkia

Recommended D levels not enough - 0 views

www.charleston.net/...ended_d_levels_not_enough73081

2009 February news vitamin D vitamin_D not enough not_enough deficiency nursing mothesr infants babiesdeficient nutrition doses dosing dosage Hollis Heaney recommendations inadequate

shared by Matti Narkia on 27 Feb 09 - Cached
  • Matti Narkia on 27 Feb 09
     
    Evidence continues to pile up that the sunshine vitamin protects against much more than bone-softening rickets. Vitamin D, also found in milk and oily fish, is becoming king, from fighting colds to preventing cancer. Investigators at the Medical University of South Carolina shut down part of a National Institutes of Health study that left nursing mothers and infants deficient, even though the mothers received the maximum safe amount of vitamin D allowed by the Institute of Medicine.\n\nBut here's the kicker. New research suggests we're not getting nearly enough, and recommended levels may be woefully inadequate.
Matti Narkia

Consuming Too Much Sugar Shortens Lifespan - 0 views

www.medicalnewstoday.com/...141588.php

2009 March medicalnewstoday news sugar over-consumption consumption lifespan aging ageing nutrition age-related diseases age-related_diseases

shared by Matti Narkia on 11 Mar 09 - Cached
  • Matti Narkia on 11 Mar 09
     
    The fact that an animal's lifetime is prolonged by decreasing its sugar ingestion is commonly recognized. In a study published in the journal PLoS Genetics, scientists from the Université de Montréal, reveal that sugar in itself is not the key element but the cells' capacity to detect its presence is.
Matti Narkia

Soybean Product Fights Abnormal Protein Involved In Alzheimer's Disease - 0 views

www.sciencedaily.com/...090218223842.htm

2009 February sciencedaily news natto nattokinase Alzheimer's disease Alzheimer's_disease Alzheimer's Alzheimer amyloids nutrition soybeans soy fermented

shared by Matti Narkia on 25 Feb 09 - Cached
  • Matti Narkia on 25 Feb 09
     
    ScienceDaily (Feb. 20, 2009) - A vegan food renowned in Asia for its ability to protect against heart attacks also shows a powerful ability in lab experiments to prevent formation of the clumps of tangled protein involved in Alzheimer's disease, scientists in Taiwan are reporting. \n\nRita P. Y. Chen and colleagues point out that people in Asia have been eating natto - a fermented food made from boiled soybeans -for more than 1,000 years. Natto contains an enzyme, nattokinase, that has effects similar to clot-busting drugs used in heart disease.Nattokinase is sold a dietary supplement to impro 
Matti Narkia

Another Blow to Magic Bullet Drugs: Statins Impair Brains - 0 views

www.naturalnews.com/025718.html

2009 February news statins impair brain cholesterol neurotransmitters memory cognition brain_function CVD CHD

shared by Matti Narkia on 25 Feb 09 - Cached
  • Matti Narkia on 25 Feb 09
     
    It turns out that statins inhibit not only the liver from making cholesterol but may also block the brain from making cholesterol. That's a serious consequence, according to Yeon-Kyun Shin, a biophysics professor in the department of biochemistry, biophysics and molecular biology at Iowa State, because cholesterol is vital for healthy and optimum brain function. "If you deprive cholesterol from the brain, then you directly affect the machinery that triggers the release of neurotransmitters. Neurotransmitters affect the data-processing and memory functions. In other words, how smart you are and how well you remember things," said Dr. Shin in a statement to the media.
Matti Narkia

Vitamin D may be critical to reduce multiple sclerosis risk - 0 views

www.nutraingredients.com/...reduce-multiple-sclerosis-risk

2009 February news vitamin D vitamin_D multiple sclerosis multiple_sclerosis MS risk HLA-DRB1*1501 risk_reduction nutrition

shared by Matti Narkia on 25 Feb 09 - No Cached
  • Matti Narkia on 25 Feb 09
     
    Supplements of vitamin D at 'critical time periods' may be key to reducing the risk of multiple sclerosis, according to a new study from the UK and Canada. Researchers report that vitamin D may interact with a specific genetic component called HLA-DRB1*1501 that is known to increase the risk of multiple sclerosis by three-fold
avivajazz jazzaviva

Webicina.com * PeRSSonalized Medicine - 0 views

www.webicina.com/rss_feeds

socialmedia personalized medicine aggregator aggregators medical journal journals medical journal aggregator research study education medical education medical search medical journals

shared by avivajazz jazzaviva on 24 Mar 09 - Cached
  • avivajazz jazzaviva on 24 Mar 09
     
    PeRSSonalized Medicine is a free tool that lets you select your favourite resources and read the latest news and articles in one personalized place. You can create your own "medical journal" and as we are totally open to suggestions, let us add the journals, blogs and websites that you would like to follow. You can use it for free and without registering on Webicina. But if you're a registered user, your settings will certainly be saved properly. Read more about the details on the Webicina Blog.
Matti Narkia

Pomegranate extract could slow cartilage loss in arthritis - 0 views

www.nutraingredients.com/...ng.asp

2005 pomegranate fruit extract arthritis cartilage osteoarthritis nutrition health diseases disease science news

shared by Matti Narkia on 25 Feb 09 - Cached
  • Matti Narkia on 25 Feb 09
     
    Pomegranate fruit extracts have been shown to block enzymes that contribute to cartilage degradation in osteoarthritis, a condition that currently has little perspective for treatment. The findings, although still at a preliminary stage not yet proven in humans, are likely to encourage further consumption of pomegranate juice in the UK, where sales have rocketed in the last year thanks to media coverage of its antioxidant content.
Matti Narkia

Pomegranate juice's heart benefits backed by study - 0 views

www.nutraingredients-usa.com/...ng.asp

2005 pomegranate juice nutrition heart atherosclerosis CVD coronary CHD science news

shared by Matti Narkia on 25 Feb 09 - Cached
  • Matti Narkia on 25 Feb 09
     
    Pomegranate juice is remarkably rich in antioxidants, such as soluble polyphenols, tannins, and anthocyanins, which scavenge free radicals and help prevent DNA damage that can lead to a number of serious health conditions. It is also believed to have antiatherosclerotic properties, as studies in Israel have shown that the fruit juice, taken daily, prevented the thickening of arteries and slowed down cholesterol oxidation by almost half (Clin Nutr. 2004 Jun;23(3):423-33).
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