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Matti Narkia

Another Blow to Magic Bullet Drugs: Statins Impair Brains - 0 views

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    It turns out that statins inhibit not only the liver from making cholesterol but may also block the brain from making cholesterol. That's a serious consequence, according to Yeon-Kyun Shin, a biophysics professor in the department of biochemistry, biophysics and molecular biology at Iowa State, because cholesterol is vital for healthy and optimum brain function. "If you deprive cholesterol from the brain, then you directly affect the machinery that triggers the release of neurotransmitters. Neurotransmitters affect the data-processing and memory functions. In other words, how smart you are and how well you remember things," said Dr. Shin in a statement to the media.
Matti Narkia

Maternal Dietary Supplementation with Pomegranate Juice Is Neuroprotective in an Animal... - 0 views

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    Loren DJ, Seeram NP, Schulman RN, Holtzman DM. \nMaternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury.\nPediatr Res. 2005 Jun;57(6):858-64. Epub 2005 Mar 17.\nPMID: 1577483
Matti Narkia

Pomegranate Juice For Moms May Help Babies Resist Brain Injury - 0 views

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    ScienceDaily (July 1, 2005) - St. Louis, June 28, 2005 -- Expectant mothers at risk of premature birth may want to consider drinking pomegranate juice to help their babies resist brain injuries from low oxygen and reduced blood flow, a new mouse study from Washington University School of Medicine in St.
Matti Narkia

Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of actio... - 0 views

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    Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives. Volvert ML, Seyen S, Piette M, Evrard B, Gangolf M, Plumier JC, Bettendorff L. BMC Pharmacol. 2008 Jun 12;8:10. PMID: 18549472 doi:10.1186/1471-2210-8-10 Conclusion Our results show that, though benfotiamine strongly increases thiamine levels in blood and liver, it has no significant effect in the brain. This would explain why beneficial effects of benfotiamine have only been observed in peripheral tissues, while sulbutiamine, a lipid-soluble thiamine disulfide derivative, that increases thiamine derivatives in the brain as well as in cultured cells, acts as a central nervous system drug. We propose that benfotiamine only penetrates the cells after dephosphorylation by intestinal alkaline phosphatases. It then enters the bloodstream as S-benzoylthiamine that is converted to thiamine in erythrocytes and in the liver. Benfotiamine, an S-acyl derivative practically insoluble in organic solvents, should therefore be differentiated from truly lipid-soluble thiamine disulfide derivatives (allithiamine and the synthetic sulbutiamine and fursultiamine) with a different mechanism of absorption and different pharmacological properties.
Robert Peil

When it comes to brain protection, there is nothing quite like blueberries! - 0 views

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    Improved Memory and Brain Function is now suggested by a new report on blueberries by Russell Martin. This research has linked blueberries with improved memory retention and motor coordination that normally accompany aging.
Matti Narkia

Beyond Sleep: New Medical Applications for Melatonin - Life Extension - 0 views

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    To the surprise of doctors around the world, melatonin is demonstrating life-saving benefits that far exceed its common use as a sleep aid.1 Increasingly, researchers have shown that melatonin's impressive ability to control oxidative damage in systems throughout the body can reduce the trauma of brain injury, prevent heart muscle damage, offer neuroprotection, increase cognitive functioning, and reduce the toxic effects of chemotherapy while enhancing its benefits.2-7 Cumulatively, these findings add up to important new roles for melatonin not only in disease prevention but in almost every field of medicine.
Matti Narkia

Chocolate Drink Could Help You Do The Math - 0 views

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    Foods rich in cocoa may improve performance on challenging mental tasks like arithmetic. This is the finding of a study presented as part of a symposium highlighting the potential of plant-based treatments presented at the British Psychological Society Annual Conference 2009 in Brighton. Crystal Haskell from the Brain, Performance and Nutrition Research Centre at Northumbria University said: "Foods containing high levels of cocoa flavanols, found in chocolate, have been shown to increase cerebral blood flow, and it has also been proven that consumption of plants that have these properties improves performance on mentally demanding tasks. We wanted to discover whether cocoa flavanols produced the same effect.
Matti Narkia

Sham vs. Wham: The Health Insider: Fermented Asian Food Shown to Have Possible Protecti... - 0 views

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    People in Asia have been eating fermented foods for more than 1,000 years. One vegan fermented food, renowned in Asia for its ability to protect against heart attacks, was recently shown to have a powerful ability in lab experiments to prevent formation of the clumps of tangled protein involved in Alzheimer's disease. if this works as well in the human brain as scientists expect, it will be a great addition to the tables of anyone who is concerned about this terrible disease
odiedog garfield

Moderate Exercise: The Elixir of Mental Health - 0 views

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    How exercise can positively effect the biochemical properties of the brain.
Graham Perrin

To Pluck a Rooted Sorrow | Print Article | Newsweek.com - 0 views

  • science of forgetting
  • Long-term memories
  • altered and then it is stored again
  • ...23 more annotations...
  • aren't fixed in a permanent form once they're filed away in the brain
  • ramps up the memory-processing machinery
  • supercritical or meaningful or scary
  • stress hormones alert the amygdala, the brain's emotional control center
  • The original memory? No longer there.
  • superhappy sticky stuff is fun
  • cognitive behavioral therapy
  • isn't wildly successful
  • drops to one third
  • improve by only about 50 percent
  • but every time they were recalled?
  • what if memories were consolidated not just once,
  • original memory could be changed and "reconsolidated"?
  • Researchers first proposed reconsolidation in the late 1960s
  • our remembrance of a single experience lands like confetti in the brain
  • dry facts
  • appear to lodge in the hippocampus
  • emotional trauma of that same event
  • seem to be housed in the amygdala
  • both parts emerge together
  • People cherish their memories, even their bad memories
  • they want to recall them with less pain
    • Graham Perrin
       
      Agreed.
  • removing memory gets into dangerous territory
Matti Narkia

Exposure to diesel exhaust induces changes in EEG in human volunteers - Particle and Fi... - 0 views

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    Exposure to diesel exhaust induces changes in EEG in human volunteers. Crüts B, van Etten L, Törnqvist H, Blomberg A, Sandström T, Mills NL, Borm PJ. Part Fibre Toxicol. 2008 Mar 11;5:4. PMID: 18334019 doi:10.1186/1743-8977-5-4
Matti Narkia

B Vitamins May Cut Stroke Risk - Neurology (Brain and Nerve) Conditions, Diseases, Medi... - 0 views

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    Feb. 20, 2009 (San Diego) -- High doses of B vitamins may help prevent stroke in high-risk people, new research suggests.\n\nThe finding comes from the Heart Outcomes Prevention Evaluation 2 trial of more than 5,500 men and women with heart disease. Participants were assigned to a daily regime
Matti Narkia

Recent advances in berry supplementation and age-related cognitive decline. - [Curr Opi... - 0 views

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    Recent advances in berry supplementation and age-related cognitive decline. Willis LM, Shukitt-Hale B, Joseph JA. Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):91-4. Review. PMID: 19057194
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