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Lee Vander Loop

Ischemic Cell Death in Brain Neurons -- Lipton 79 (4): 1431 -- Physiological Reviews - 0 views

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    Physiological Reviews - Department of Physiology, University of Wisconsin School of Medicine - Ischemic Cell Death in Brain Neurons - defining Cell Death - Major Features of Ischemic Cell Death - Ischemic Cell Death and Hypoxia
Lee Vander Loop

Calcium in Ischemic Cell Death. [Stroke. 1998] - PubMed result - 0 views

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    PubMed Abstract of review article on the role of calcium in ischemic cell death. Review concluded that calcium is one of the triggers involved in ischemic cell death, whatever the mechanism.
Lee Vander Loop

The Fern Laboratory - Research on Ischemic Injuries in the Neonatal Brain - 0 views

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    The Fern Lab - The Fern lab is located in the Department of Neurology at the University of Washington in Seattle. The lab's research focuses on ischemic injury of the brain, in particular the neonatal/developing brain. Ischemia is the term given to a loss of blood supply and can arise due to obstruction of a blood vessel (leading to a stroke), or from factors that are currently not well understood but which produce the brain injury that underlies cerebral palsy.
Lee Vander Loop

The Association of Cerebral Palsy with Other Disability in Children with Perinatal Arte... - 0 views

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    PubMed Central Abstract of study examining the Association of Cerebral Palsy with Other Disability in Children with Perinatal Arterial Ischemic Stroke
Lee Vander Loop

Hypoxic-Ischemic Encephalopathy: eMedicine Pediatrics: Cardiac Disease and Critical Car... - 0 views

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    emedicine Hypoxic-Ischemic Encephalopathy Overview
Lee Vander Loop

Study of Cerebrolysin for Treatment of Neonatal Hypoxic Ischemic Encephalopathy - 0 views

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    Study is to determine whether nerve growth factor (cerebrolysin®) therapy will improve the psychomotor outcome in infants with moderate and severe hypoxic ischemic encephalopathy.
Lee Vander Loop

Amplitude-Integrated EEG Is Useful in Predicting Neurodevelopmental Outcome in Full-Ter... - 0 views

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    Journal of Child Neurology - Amplitude-Integrated EEG is useful in predicition of Neurodevelopmental Outsome in Full-Term Infants with Hypoxic-Ischemic Encephalopathy: A Meta-Analysis
Lee Vander Loop

[Birth asphyxia and hypoxic ischemic encephalopath... [Laeknabladid. 2007] - PubMed result - 1 views

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    2007 Icelandic study to assess the incidence, obstetric risk factors and the squela of severe asphyxia at Landspitali university hospital.
Lee Vander Loop

Antenatal Allopurinol During Fetal Hypoxia - UMC Utrecht - 0 views

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    Study to determine if Antenatal Allopurinol Administration Reduce Post-Hypoxic-Ischemic Reperfusion Damage During Fetal Hypoxia in the Newborn
Lee Vander Loop

Long-term evaluation of granulocyte-colony stimula... [Intensive Care Med. 2010] - PubM... - 0 views

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    Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological out come of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to investigate the long-term functional and protective actions of granulocyte-colony stimulating factor (G-CSF) treatment in an experimental model of cerebral. RESULTS: Granulocyte-colony stimulation promoted somatic growth and prevented brain atrophy and underdevelopment of the heart in infant rats.
Lee Vander Loop

Late Hypothermia for Hypoxic-Ischemic Encephalopathy - 0 views

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    Clinical trial being sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD to evaluate whether induced whole-body hypothermia initiated between 6-24 hours of age and continued for 96 hours in infants ≥ 36 weeks gestational age with hypoxic-ischemic encephalopathy will reduce the incidence of death or disability at 18-24 months of age.
Lee Vander Loop

Systemic Hypothermia Improves Outcome of Hypoxic-Ischemic Encephalopathy - 1 views

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    Completed Zhengzhou University study to investigate whether systemic hypothermia induced up to 10 hrs after birth would improve the neurodevelopmental outcome at 18 months in infants with moderate or severe HIE.
Lee Vander Loop

MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(H... - 1 views

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    Hundreds of babies in the world are being treated with brain cooling to prevent brain injury after they lose oxygen at birth. This study will use the newly developed information from the magnet resonance image to determine the actual temperature of the brain. This will enable researchers to determine if the brain is being uniformly cooled and if techniques that provide cooling need to be changed to improve the injury prevention from cooling
Lee Vander Loop

Perinatal asphyxia - 1 views

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    Neuropathology online - Course material - Asphyxia and hypoxic-ischemic encephalopathy in mature infants
Lee Vander Loop

Apgar scores at 10 m... [Pediatrics. 2009] - PubMed - 3 views

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    Objective of this study was to determine whether Apgar scores at 10 minutes are associated with death or disability in early childhood after perinatal hypoxic-ischemic encephalopathy.
Lee Vander Loop

Intrathecal Stem Cells in Brain Injury - 1 views

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    Current ongoing study being conducted to determine whether the plasticity of autologous intrathecal hematopoietic cells would improve the neurologic evolution of the pediatric patients with hypoxic ischemic brain injury.
Lee Vander Loop

CoolCap Trial, Treatment of Perinatal Hypoxic-Ischemic Encephalopathy - 0 views

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    Completed research study of head cooling to determine whether cooling babies' heads can reduce or prevent brain damage that may have resulted from temporarily reduced oxygen supply to the brain
Lee Vander Loop

[Physical and neurological state of the newborn af... [Usp Fiziol Nauk. 2007 Oct-Dec] -... - 0 views

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    NIH PUbMed Abstract of Russian study documenting the Physical and neurological state of the newborn afer perinatal asphyxia.This paper is presented as modern conceptions about asphyxia origin, risk factors, neurological and systemic complications for child nervous system and organism.
Lee Vander Loop

Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants - China Medical ... - 0 views

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    A recent study using high-dose rhEpo (3000 U rhEpo/kg body weight at birth) for neuroprotection in very preterm infants revealed that no signs of adverse effects of early high-dose rhEpo treatment in very preterm infants were identified. Contrary to this, a recent study in PVL of a rat model revealed that using a low dose rhEpo (50-100 U/kg) was effective in the treatment of brain damage induced by hypoxia-ischemia and did not affect normal oligodendrocyte maturity. On this basis, the researchers intent to investigate (1) whether low-dose rhEpo (100 U/kg) or high-dose rhEpo (3,000 U/kg) given to very preterm infants (gestation age < 32 weeks) immediately after birth and subsequently during the first 2 days is safe and possesses neuroprotective properties;(2) whether there are gender differences in response to the hypoxia-ischemic insult and EPO treatment; (3)the pharmacokinetics of low dose and high dose rhEPO.
Lee Vander Loop

The impact of Neonatal Resuscitation Program cours... [Brain Dev. 2008] - PubMed result - 1 views

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    Trakya University School of Medicine, Turkey study to evaluate the impact of the Neonatal Resuscitation Program (NRP) on morbidity and mortality of newborn infants with perinatal asphyxia. The study concluded that after Neonatal resuscitation (RP) courses, the number of patients with perinatal asphyxia and with no resuscitation and also the duration of hospitalization decreased significantly, whereas the first minute Apgar scores increased significantly.
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