Cerebral Palsy International Research Foundation CPI - Injury to the Preterm Brain and Cerebral Palsy - Part 1: Clinical Aspects of Injury to the Preterm Brain
Study to compare rates, nature, and mechanisms of school injuries in children with and without disabilities. Conclusions: For children with disabilities, physical impairment may play a greater role than cognitive impairment in managing risk for injury at school. Individual education programs (IEP), developed for children in special education, could be tailored to include injury prevention strategies.
University of Medicine & Dentistry of New Jersey 2007 Study documents Widespread Repair of Neonatal Brain Injury from Adult Stem Cells - Neuroscientists at UMDNJ-New Jersey Medical School have discovered that the neonatal brain possesses a previously unknown capacity to replace damaged neurons in multiple brain regions. Furthermore, their research reveals that the production of these new neurons lasts for at least five months following injury.Levison's study reveals that in addition to neurons acquiring new or different responsibilities, that another adaptive response, one that has not been suspected, occurs. Their data show that large numbers of new neurons are produced from the brain's resident stem cells during their recovery from injury. These findings suggest that these new neurons are further increasing the infant brain's ability to repair itself after injury.
The Fern Lab - The Fern lab is located in the Department of Neurology at the University of Washington in Seattle. The lab's research focuses on ischemic injury of the brain, in particular the neonatal/developing brain. Ischemia is the term given to a loss of blood supply and can arise due to obstruction of a blood vessel (leading to a stroke), or from factors that are currently not well understood but which produce the brain injury that underlies cerebral palsy.
Providing a wealth of information, solutions and leadership on issues related to brain injury . Services and Resources on the site reflect the best practices in the field of Traumatic Brain Injury
LifeBridge Health - The Sandra and Malcolm Berman Brain & Spine Institute - Center for Memory and Brain Health. PROGRAMS Include: The Epilepsy Center, The Spine Center, the Brain Injury Programs, Adult Hydrocephalus Center, Pain Management program and Traumatic Brain Injury as well as several other programs. The Traumatic Brain Injury and Neuro-Rehabilitation units provide medical recovery and improve patients' quality of life.
Citicoline Brain Injury Treatment (COBRIT) trial of the effects of 90 days of citicoline on functional outcome in patients with complicated mild, moderate and severe traumatic brain injury. Citicoline (also known as CDP-Choline) is a naturally occurring endogenous compound. Citicoline may have neuroprotective effects and may potentiate neuro-recovery which has led to the evaluation of it as treatment for both stroke and TBI in animal models and in human clinical trials.
The SyNAPSe trial will study if giving intravenous (i.v.) progesterone within 8 hours of the injury for a total of 120 hours to severe traumatic brain injury patients improves their recovery.
Acute birth asphyxia is a cause of death and neurological injury. At present, there is no proven treatment; however, studies in animals suggest that brain cooling may protect against brain injury. This large multicenter trial will randomize term infants with a history of problems at delivery and signs of depression to total body cooling or standard care.
Research/study hypothesis is that topiramate will reduce acute seizures after traumatic brain injury and will help prevent the development of epilepsy after traumatic brain injury.
The Solomon H. Snyder Department of Neuroscience - the Johns Hopkins University - Asst Professor Mary Ann wilson, PhD - Mechanisms of Development, Plasticity and Injury in the Immature Brain
PubMed.gov Study Abstract - Study to identify neonatal risk factors for cerebral palsy among very preterm babies and in particular the associations independent of the coexistence of antenatal and intrapartum factors.