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Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological out come of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to investigate the long-term functional and protective actions of granulocyte-colony stimulating factor (G-CSF) treatment in an experimental model of cerebral. RESULTS: Granulocyte-colony stimulation promoted somatic growth and prevented brain atrophy and underdevelopment of the heart in infant rats.

2007 Clinical trial to determine the effectiveness of acupuncture when used as an adjunct to intense conventional physical, occupational and hydro therapies to improve function and quality of life in children with Spastic Cerebral Palsy.

PubMed Abstract of double-blind study of high cervical spinal cord stimulation conducted in eight moderately disabled, spastic, cerebral palsied children failed to demonstrate any significant improvement over base line function during chronic spinal cord stimulation at either optimal stimulation parameters or random placebo parameters

Neuroscience for Kids - Types of Neurons (Nerve Cells)

The mission of the ASNR is to promote the medical and social wellbeing of persons with disabling neurological disorders, to advance training and research in the basic and clinical sciences that can lead to functional recovery of neurologically impaired persons, and to disseminate the knowledge of this research among professionals and the general public.

2008 Pub Med Abstract assessing Stress in parents of children with cerebral palsy: what sources of stress are we talking about? Study to explore the relation between aspects of parental distress in the parenting role and the child's limitations in functional skills and the child's behavioural difficulties, in parents of children with CP.

CRANIAL SACRAL THERAPY (CST) is a potent tool using the functions of the Cranial Sacral system. It is an effective form of bodywork and of Neuromuscular Therapy which uses gentle movements to unlock tension and relieve pain. There are no rapid adjustments, painful contortions, or deep muscle probing.

Fragile X syndrome is the leading hereditary cause of developmental disabilities in all populations. The absence of a functional fragile X gene shuts off production of a special protein in the brain needed for normal cognitive development. Without this protein, children with the syndrome will never learn normally, despite hours of therapy and rehabilitation.

Provides Child Therapy Products and Special Needs Toys

Stanford University sponsored study of trihexyphenidyl in children with upper extremity dystonia due to cerebral palsy. It is hypothesized that trihexyphenidyl in doses up to 0.75mg/kg/day would be well-tolerated and show significant changes on the Melbourne scale of upper extremity function.

Study being sponsored by the University of Virginia to examine the effects of gentle movements applied to the ankle joint and stretching on self-reported function, ankle motion and stiffness in individuals who have suffered from an ankle sprain within the last year and have decreased ankle motion

Completed study sponsored by NINDS designed to use positron emission tomography to measure brain energy use. Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of normal individuals and patients with neurologic illnesses without physical / structural damage to the brain.

Planned study to evaluated how children with Cerebral Palsy move their legs differently from children without CP. Additional objective to determine if an exercise program can improve leg coordination in children with CP

Information on planned study to determine effects of power mobility on the development and function of children with severe physical disabilities

Information on completed study to classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking."

Cincinnati Children's is conducting a research project to study the white matter of the brain in children with hydrocephalus (white matter connects areas in the brain responsible for normal function). Assessments will be done through MRIs and neuropsychological tests of behavior and development.

This study is an observational study to prove that a new device, which measures the force of delivering a baby, (US patent 6,684,165) functions as described in the patent. This is the first time this has been used with patients. The device measures the force (pounds/kilograms) that is exerted as a doctor/midwife pulls on a baby during the delivery

NINDS sponsored study will examine the safety and effectiveness of infusing a chemical called muscimol into the brain to control seizures in patients with intractable epilepsy (frequent seizures that persist despite therapy). Muscimol, which is similar to a naturally occurring brain chemical called GABA, has been shown to reduce seizures in rats.

Completed study on Motilin, a peptide, whose action is controlled by motilin receptors located in the gut. Action of Motilin at motilin receptors increases the gastric emptying rate (rate of emptying of food and fluid from the stomach). Compounds which stimulate motilin receptors therefore provide a potential approach to the treatment of a range of clinical conditions where delayed gastric emptying may contribute to symptoms, such as enteral feeding ntolerance (post-operative or intensive care patients), gastroparesis, diabetic gastroparesis, and functional dyspepsia. This study is the First Time In Human study for the motilin receptor agonist, GSK962040.

The relation between eye movement and brain function is a subject of interest to the National Eye Institute. By comparing eye movement in healthy volunteers to research conducted on patients who have difficulty moving their eyes, the National Eye Institute hopes to develop and improve diagnostic procedures for people with eye diseases. Objectives: To study eye movement in 100 healthy adult and child volunteers. To understand how individuals see visual patterns and how eye movement affects the ability to see.