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The congressional legislation that created the National Eye Institute (NEI) mandates research on amelioration of the impact of impaired vision and blindness on health and well- being. The current NEI research program on visual impairment and its rehabilitation can be divided into six areas. Laboratory research is a fundamental yet often underappreciated pillar of research on visual impairment and blindness. A major goal of this area is to develop a scientific basis for understanding normal visual functioning that can be extended to explain the disabilities experienced by people with low vision, blindness, and other visual processing deficits.

As part of the federal government's National Institutes of Health (NIH), the National Eye Institute's mission is to "conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind."

Completed study examined tongue strength and endurance, how the tongue applies pressure during swallowing, and how the chin muscles react during swallowing in healthy volunteers and in patients with dysphagia (difficulty swallowing). The information from this study may be helpful in developing better treatments for people with swallowing problems

Study completed and sponsored by Hvidovre University Hospital to investigate if physical therapy with strength training is better at improving muscle and gait function after anti-spastic treatment with Botulinum toxin compared to physical therapy without strength training in children with cerebral palsy.

The Johns Hopkins Medicine Brain Science Institute's (BSi) mission is to solve fundamental questions about brain development and function and to use these insights to understand the mechanisms of brain disease

Effect of treatment on the movement disorder will be measured by a myoclonus scale and a dystonia scale as well as by assessment of overall functional status. Response at various dosages will be compared to baseline for all patients.Safety parameters including neurological examination, blood tests and EKG will be monitored throughout the treatment period and during withdrawal of the medication.