Hospital de Clinicas de Porto Alegre completed study evaluated the efficacy and safety of a phytotherapeutic laxative tea, composed by Pimpinella anisum, Foeniculum vulgare, Sambucus nigra and Cassia angustifolia, in a randomized crossover placebo-controlled clinical trial in
patients with chronic constipation.
Completed clinical study compared the treatment effects of rabeprazole and lansoprazole depending on the genetic constitution of a enzyme in the liver in treating reflux esophagitis and the cure rate on endoscopy after treatment with rabeprazole 20 mg or lansoprazole 30 mg once daily for 4 to 8 weeks.
Completed study assessed the pharmacokinetics and safety of dexlansoprazole, once daily (QD), in pediatric subjects with symptomatic Gastroesophageal Reflux
Disease.
Study is to obtain preliminary information about the efficacy and potential adverse effects of platelet concentrate injections in patients undergoing arthroscopic Sub-acromial Decompression (SD), arthroscopic Acromio-Clavicular (AC) joint resection, and arthroscopic Rotator Cuff (RC) repair. Investigators wish to determine whether the PRP shows efficacy in healing and learn of possible side-effects
Safety and Efficacy of Vanquix™ Auto-Injector (Diazepam Injection) for the Management of Selected, Refractory Patients With Epilepsy Who Require Intermittent Medical Intervention to Control Episodes of Acute Repetitive Seizures
Study comparing diazepam, a drug that is labeled by the FDA for this indication, with lorazepam. The study will show whether one drug is more effective and safer than the other.
Study to determine if Inhaled Nitric Oxide (iNO) given into an oxygen hood is effective in improving oxygenation in term and near-term infants who have poor oxygenation but who are not yet mechanically ventilated.
The purpose of this study is to determine the long-term safety profile of daily treatment with dexlansoprazole MR in subjects with gastroesophageal reflux disease.
Endotracheal intubation is a painful and stressful procedure, which is associated with acute increases of blood pressure, intracranial pressure, bradycardia and hypoxemia with high morbidity.The aim of the study is to compare recovery time, efficacy and tolerance in a andomized controlled study, between sevoflurane and propofol for intubation in neonates in Neonatal Intensive Care Unit.
Completed study is to verify superiority of the lafutidine group over the placebo group and non-inferiority to the famotidine group in terms of endoscopic healing rate of the patients with mild reflux oesophagitis.
Proposed study is designed to evaluate patients at particular risk for preterm delivery; those with advanced cervical exam. In this randomized prospective controlled study, we intend to examine the influence of adjunctive antibiotic use in preterm labor complicated by a cervical exam of 4 cm or greater. Comparison will be made between a study group receiving broad-spectrum antibiotics with a control group that will not receive antibiotics for pregnancy prolongation
Study to determine responses of lansoprazole and ecabet sodium combination therapy and compare with lansoprazole and placebo therapy in patients who need additional therapy after standard proton pump inhibitor treatment for 4week or more in recurrent gastroesophageal reflux disease.
Completed study to Compare the Efficacy and Safety of Levofloxacin and Standard of Care Therapy in the Treatment of Children With Community-Acquired Pneumonia in the Hospitalized or Outpatient Setting
The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education program to promote the prevention and treatment of heart, lung, and blood diseases and enhance the health of all individuals so that they can live longer and more fulfilling lives. NHLBI stimulates basic discoveries about the causes of disease, enables the translation of basic discoveries into clinical practice, fosters training and mentoring of emerging scientists and physicians, and communicates research advances to the public. Creates and supports a robust, collaborative research infrastructure in partnership with private and public organizations, including academic institutions, industry, and other government agencies
This study is being conducted to gather medium and long-term information regarding the performance and safety of the commercially available DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System.
The IDD Branch sponsors research and research training aimed at preventing and ameliorating intellectual and related developmental disabilities. The program supports biomedical, biobehavioral, behavioral, and translational research in etiology, pathophysiology, screening, prevention, treatment, and epidemiology.
Completed study sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD and conducted in two cities in Zambia to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared to the new World Health Organization (W.H.O.) basic perinatal care education of health care providers (Essential Newborn Care Program) results in reduced mortality due to perinatal asphyxia
NICHD program focuses on developing research that links PCCR medicine and science to the epidemiology, prevention, and treatment of childhood disabilities. The effort sponsors competitive research on all aspects of PCCR-including critical analyses of outcomes for children who are survivors of trauma, congenital anomalies, neonatal asphyxia, infectious processes, septic shock, and many other less common, but still devastating hildhood processes. The PCCR program also provides support for the Pediatric Critical Care Scientist Development Program (PCCSDP) , a national faculty training and career development program that develops successful pediatric critical care physician scientists conducting research to enhance the scientific understanding, clinical management, and rehabilitation of pediatric critical illness.
Ongoing study sponsored by the University of Utah to determine the percentage of patients presenting with dysphagia who are found to have eosinophilic esophagitis
(EoE) and to establish which presenting factors warrant esophageal biopsies.