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Amanda Bergstedt

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection - 0 views

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    Researchers have been able to reconstruct the genome sequence of a bacterial strain which bypasses the need for growing bacteria in the lab. This could stop an outbreak in its tracks due to the increased speed of identifying the bacteria.
Megan Goldman

Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfametho... - 0 views

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    Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Frontiers in Antimicrobials, Resistance and Chemotherapy publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Antimicrobials, Resistance and Chemotherapy.
Elijah Velasquez

Bacterial byproduct offers route to avoiding antibiotic resistance - 0 views

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    Increasing ROS (reactive oxygen species) in bacteria allow current antibiotics to be more potent. This approach weakens the bacteria allowing lower doses of antibiotics to be effective. This is can potentially help reduce the rate of antibiotic resistance. As we continue to develop a greater understanding about disease causing bacteria we can expose numerous ways to weaken the bacteria.
Amy Jorgenson

Search for new antibiotics advanced by discovery of key processes within bacterial protein - 0 views

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    Scientists have recently discovered how pili are formed, giving another potential target for antimicrobial medications
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    A rather novel discovery in the field of pili biogenesis. This also appears to be a big steeping stone in the development of potential new antibiotics for cystitis (bladder inflammation a.k.a urinary tract infections).
Tyrell Varner

Bacteria evolve resistance more quickly when stronger antibiotics are used - 1 views

  • they found that the rate of evolution of antibiotic resistance speeds up when potent treatments are given because resistant bacterial cells flourish most during the most aggressive therapies.
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    Hmm common sense?
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    Kind of. So if you remove the competition more completely with aggressive antibiotics, the proportion of remaining bacteria that are resistant is higher. Of course, the opposite happens when you treat incompletely with antibiotics (i.e. stop taking them early). In that case our thinking is that the immune system is unlikely to kill all the remaining bacteria, increasing the chance resistant bacteria will survive.
Megan Goldman

BMC Microbiology | Full text | Cultivation conditions and the diffusion of oxygen into ... - 0 views

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    Bacterial cultivation requires consideration of three things: The bacterial strain, cultivation medium, and cultivation conditions. Most microbiologists dutifully report their choice of strains and cultivation media in manuscripts; however, these same microbiologists often overlook reporting cultivation conditions. Without this information, it is difficult to determine if cultures were grown aerobically, microaerobically, or anaerobically.
Whitney Hopfauf

Electron-beam pasteurization of raw oysters may reduce viral food poisoning - 0 views

  • FDA already has approved the use of electron beam technology as a pathogen intervention strategy to control the naturally occurring Vibrio vulnificus bacterial pathogen in shellfish.
    • Whitney Hopfauf
       
      Good that it has already been approved by the FDA... step in the right direction
  • Praveen said she and the other researchers also chose the viral pathogens as opposed to bacterial as they were more difficult to treat and also require a host species.
  • if a serving size of 12 raw oysters were contaminated with approximately 100 hepatitis A and human noroviruses, an e-beam dose of 5 kGy (kilograys) would achieve a 91 percent reduction of hepatitis A infection risks and a 26 percent reduction of norovirus infection risks.
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    • Whitney Hopfauf
       
      Pretty significant except it still doesn't make me want to eat raw shellfish
  • how electron-beam pasteurization of raw oysters may reduce the possibility of food poisoning through virus.
  • results of this study will be published in the June
  • using a human norovirus surrogate called murine norovirus
  • uses commercial electricity
  • green technology because no chemicals are involved."
Jenna Veldhuizen

Discovery holds potential in destroying drug-resistant bacteria - 0 views

  • Dr. Montelaro and his colleagues found that a particular sequence of amino acids on the tail end of HIV allow the virus to "punch into" and infect cells. The team manufactured a synthetic and more efficient version of this sequence -- called engineered cationic antimicrobial peptides, or "eCAPs" -- that laboratory tests have shown to rapidly destroy bacteria that are otherwise resistant to most standard antibiotics.
  • Traditional antibiotics typically work by poisoning important metabolic processes after being taken up by the target bacteria, a process that may take hours, or days, to clear a bacterial infection. In contrast, the eCAPs are specifically attracted to the surface of target bacteria where they disrupt the bacterial membrane, causing death within seconds, or minutes.
  • eCAPs work well against biofilms
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    very interesting...the same mechanism HIV uses to infect cells can be manufactured and used to destroy antibiotic-resistant bacteria
Richard Herron

Viruses Can Have Immune System, Study Finds | Biology | Sci-News.com - 1 views

  • A new research led by Dr Kimberley Seed from the Tufts University School of Medicine provides the first evidence that bacteriophages – viruses that infect and replicate within bacteria – can acquire a wholly functional and adaptive immune system.
  • The study, published today in the journal Nature, finds that a viral predator of the cholera bacteria can steal the functional immune system of bacteria and use it against its bacterial host.
  • Developing phage therapy is particularly important because some bacteria, called superbugs, are resistant to most or all current antibiotics.
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  • This study focused on a phage that attacks Vibrio cholerae, the bacterium responsible for cholera epidemics in humans.
  • Finding a CRISPR/Cas system in a phage shows that there is gene flow between the phage and bacteria even for something as large and complex as the genes for an adaptive immune system,”
Abdirizak Abdi

Cell Therapy Promising for Acute Type of Leukemia - 0 views

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    Exciting experimental treatment that stops cancer cells. The treatment uses the patient's own T-cells(disease fighting cells) and uses some sort of virus as a vector to change those cells into cancer fighting cells. My concern was was is there a damage done to other immune systems cells that also have the CD19 molecule on their surface? dendritic cells to name, which is mandatory for the body to fight both bacterial as well as viral infections. You wipe the dendritic cells and that introduces opportunistic infections. Regardless amazing news.
Alison Prodzinski

Bathing, but Not Alone - NYTimes.com - 0 views

  • Another paradox of city life: it seems it is healthier to inhale the subway’s air than the shower’s mist.
  • the deluge of bacteria that hit your face and flow deep into your lungs in the morning shower
  • Running the water for 30 seconds before stepping in would mean fewer bacteria in one’s face
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  • Aside from the thought of being sprayed in the face by a bacterial cocktail every morning, the shower bacteria present no serious danger
  • the subway air is remarkably fresh and like outdoor air
  • Another paradox of city life: it seems it is healthier to inhale the subway’s air than the shower’s mist.
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    Bacteria are everywhere - including the shower!! There are 15 different kinds of bacteria that live in the shower -- they get into your lungs via inhalation and your skin. These bacteria are not all bad though - only Mycobacterium avium - it can cause chest complaints and issues. Research on the shower and bacteria was then compared to a New York City subway - in which the subway was healthier then the shower! WOW!! However, hope is not lost - researchers said to run the shower for 30 seconds and most bacteria will be gone!!
Tyrell Varner

Research harnesses solar-powered proteins to filter harmful antibiotics from water - 0 views

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    A new filter made of two bacterial proteins was able to absorb 64% of antibiotics in surface water compared to about 40% absorbed by the currently used filtering technology made of activated carbon. The captured antibiotics can also be harvested from the proteins.
Katelyn Madigan

Secrets of bacterial slime revealed - 1 views

  • help identify a new target for antibiotics and prevent other biofilms from forming
  • regulator of biofilm formation, a protein called SinR, acts in the model bacterium, Bacillus subtilis.
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    While this still seems like a somewhat preliminary study on protein interactions, I think this is an important direction for future studies due to the increased understanding of the dangers of biofilms.
Amanda Bergstedt

Rotavirus and not age determines gastroenteritis severity in children: a ho... - 0 views

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    This study shows that the children with rotavirus gastroenteritis, rather than bacterial gastroenteritis, had more severe cases of the disease. This implies the need for rotavirus vaccinations. Supplemental paper for Rotavirus presentation.
Whitney Hopfauf

Eczema in infants linked to gut bacteria - 0 views

  • Eczema is a chronic inflammation of the epidermis
    • Whitney Hopfauf
       
      The flora of the gut is being implicated in so many more diseases than ever before. I remember when the probiotic craze first started and now it has become common knowledge. Maybe we could someday treat eczema by repopulating the gut with bacteroidetes (at least in children)
  • The number of bifidobacteria naturally falls with age and in total we found 21 groups of bacteria which changed in this time period.
    • Whitney Hopfauf
       
      I remember when I was growing up, my pediatrician put me on a special kind of milk that had extra probiotics in it to combat my constant ear infections. Maybe there was more validity to that than I realized.
  • early change towards adult-type bacteria which seems to be a risk factor for eczema
    • Whitney Hopfauf
       
      I wonder what would happen in the reverse (if childhood bacterial flora was present in adults). I wonder if there is a pathology associated with that.
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  • gut bacteria
  • with or without eczema was examined when they were six and 18 months ol
  • normally
  • six months all the infants had the same types of bacteria but by 18 months old the children with eczema had more of a type of bacteria normally associated with adult
  • while the healthy children had a greater amount of Bacteroidetes.
Samantha Mishall

New metal-eating bacteria found on Titanic - 0 views

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    A new bacterial species that eats metal... what?! Just more proof that bacteria have the ability thrive anywhere, even under the most extreme conditions. Researchers worry that this new species will eventually completely eat up this historic ship.
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