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markfrankel18

Psychiatry's Mind-Brain Problem - The New York Times - 1 views

  • Recently, a psychiatric study on first episodes of psychosis made front-page news. People seemed quite surprised by the finding: that lower doses of psychotropic drugs, when combined with individual psychotherapy, family education and a focus on social adaptation, resulted in decreased symptoms and increased wellness.
  • Recently, a psychiatric study on first episodes of psychosis made front-page news. People seemed quite surprised by the finding: that lower doses of psychotropic drugs, when combined with individual psychotherapy, family education and a focus on social adaptation, resulted in decreased symptoms and increased wellness. But the real surprise — and disappointment — was that this was considered so surprising.
  • But the real surprise — and disappointment — was that this was considered so surprising.
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  • Unfortunately, Dr. Kane’s study arrives alongside a troubling new reality. His project was made possible by funding from the National Institute of Mental Health before it implemented a controversial requirement: Since 2014, in order to receive the institute’s support, clinical researchers must explicitly focus on a target such as a biomarker or neural circuit. It is hard to imagine how Dr. Kane’s study (or one like it) would get funding today, since it does not do this. In fact, psychiatry at present has yet to adequately identify any specific biomarkers or circuits for its major illnesses.
  • Unfortunately, Dr. Kane’s study arrives alongside a troubling new reality. His project was made possible by funding from the National Institute of Mental Health before it implemented a controversial requirement: Since 2014, in order to receive the institute’s support, clinical researchers must explicitly focus on a target such as a biomarker or neural circuit. It is hard to imagine how Dr. Kane’s study (or one like it) would get funding today, since it does not do this. In fact, psychiatry at present has yet to adequately identify any specific biomarkers or circuits for its major illnesses.
markfrankel18

The Moral Instinct - New York Times - 3 views

  • It seems we may all be vulnerable to moral illusions the ethical equivalent of the bending lines that trick the eye on cereal boxes and in psychology textbooks. Illusions are a favorite tool of perception scientists for exposing the workings of the five senses, and of philosophers for shaking people out of the naïve belief that our minds give us a transparent window onto the world (since if our eyes can be fooled by an illusion, why should we trust them at other times?). Today, a new field is using illusions to unmask a sixth sense, the moral sense.
  • The first hallmark of moralization is that the rules it invokes are felt to be universal. Prohibitions of rape and murder, for example, are felt not to be matters of local custom but to be universally and objectively warranted. One can easily say, “I don’t like brussels sprouts, but I don’t care if you eat them,” but no one would say, “I don’t like killing, but I don’t care if you murder someone.”The other hallmark is that people feel that those who commit immoral acts deserve to be punished.
  • Until recently, it was understood that some people didn’t enjoy smoking or avoided it because it was hazardous to their health. But with the discovery of the harmful effects of secondhand smoke, smoking is now treated as immoral. Smokers are ostracized; images of people smoking are censored; and entities touched by smoke are felt to be contaminated (so hotels have not only nonsmoking rooms but nonsmoking floors). The desire for retribution has been visited on tobacco companies, who have been slapped with staggering “punitive damages.” At the same time, many behaviors have been amoralized, switched from moral failings to lifestyle choices.
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  • But whether an activity flips our mental switches to the “moral” setting isn’t just a matter of how much harm it does. We don’t show contempt to the man who fails to change the batteries in his smoke alarms or takes his family on a driving vacation, both of which multiply the risk they will die in an accident. Driving a gas-guzzling Hummer is reprehensible, but driving a gas-guzzling old Volvo is not; eating a Big Mac is unconscionable, but not imported cheese or crème brûlée. The reason for these double standards is obvious: people tend to align their moralization with their own lifestyles.
  • People don’t generally engage in moral reasoning, Haidt argues, but moral rationalization: they begin with the conclusion, coughed up by an unconscious emotion, and then work backward to a plausible justification.
  • Together, the findings corroborate Greene’s theory that our nonutilitarian intuitions come from the victory of an emotional impulse over a cost-benefit analysis.
  • The psychologist Philip Tetlock has shown that the mentality of taboo — a conviction that some thoughts are sinful to think — is not just a superstition of Polynesians but a mind-set that can easily be triggered in college-educated Americans. Just ask them to think about applying the sphere of reciprocity to relationships customarily governed by community or authority. When Tetlock asked subjects for their opinions on whether adoption agencies should place children with the couples willing to pay the most, whether people should have the right to sell their organs and whether they should be able to buy their way out of jury duty, the subjects not only disagreed but felt personally insulted and were outraged that anyone would raise the question.
  • The moral sense, then, may be rooted in the design of the normal human brain. Yet for all the awe that may fill our minds when we reflect on an innate moral law within, the idea is at best incomplete. Consider this moral dilemma: A runaway trolley is about to kill a schoolteacher. You can divert the trolley onto a sidetrack, but the trolley would trip a switch sending a signal to a class of 6-year-olds, giving them permission to name a teddy bear Muhammad. Is it permissible to pull the lever? This is no joke. Last month a British woman teaching in a private school in Sudan allowed her class to name a teddy bear after the most popular boy in the class, who bore the name of the founder of Islam. She was jailed for blasphemy and threatened with a public flogging, while a mob outside the prison demanded her death. To the protesters, the woman’s life clearly had less value than maximizing the dignity of their religion, and their judgment on whether it is right to divert the hypothetical trolley would have differed from ours. Whatever grammar guides people’s moral judgments can’t be all that universal. Anyone who stayed awake through Anthropology 101 can offer many other examples.
  • The impulse to avoid harm, which gives trolley ponderers the willies when they consider throwing a man off a bridge, can also be found in rhesus monkeys, who go hungry rather than pull a chain that delivers food to them and a shock to another monkey. Respect for authority is clearly related to the pecking orders of dominance and appeasement that are widespread in the animal kingdom. The purity-defilement contrast taps the emotion of disgust that is triggered by potential disease vectors like bodily effluvia, decaying flesh and unconventional forms of meat, and by risky sexual practices like incest.
  • All this brings us to a theory of how the moral sense can be universal and variable at the same time. The five moral spheres are universal, a legacy of evolution. But how they are ranked in importance, and which is brought in to moralize which area of social life — sex, government, commerce, religion, diet and so on — depends on the culture.
  • By analogy, we are born with a universal moral grammar that forces us to analyze human action in terms of its moral structure, with just as little awareness. The idea that the moral sense is an innate part of human nature is not far-fetched. A list of human universals collected by the anthropologist Donald E. Brown includes many moral concepts and emotions, including a distinction between right and wrong; empathy; fairness; admiration of generosity; rights and obligations; proscription of murder, rape and other forms of violence; redress of wrongs; sanctions for wrongs against the community; shame; and taboos.
  • Here is the worry. The scientific outlook has taught us that some parts of our subjective experience are products of our biological makeup and have no objective counterpart in the world. The qualitative difference between red and green, the tastiness of fruit and foulness of carrion, the scariness of heights and prettiness of flowers are design features of our common nervous system, and if our species had evolved in a different ecosystem or if we were missing a few genes, our reactions could go the other way. Now, if the distinction between right and wrong is also a product of brain wiring, why should we believe it is any more real than the distinction between red and green? And if it is just a collective hallucination, how could we argue that evils like genocide and slavery are wrong for everyone, rather than just distasteful to us?
  • Putting God in charge of morality is one way to solve the problem, of course, but Plato made short work of it 2,400 years ago. Does God have a good reason for designating certain acts as moral and others as immoral? If not — if his dictates are divine whims — why should we take them seriously? Suppose that God commanded us to torture a child. Would that make it all right, or would some other standard give us reasons to resist? And if, on the other hand, God was forced by moral reasons to issue some dictates and not others — if a command to torture a child was never an option — then why not appeal to those reasons directly?
markfrankel18

Internet Makes Hypochondria Worse - 1 views

  • Thanks to the Internet, becoming a hypochondriac is much easier than it used to be. The easy availability of health information on the web has certainly helped countless people make educated decisions about their health and medical treatment, but it can be disastrous for people who are likely to worry. Hypochondriacs researching an illness used to have to scour books and ask doctors for information. Now a universe of information is available with a few mouse clicks. "For hypochondriacs, the Internet has absolutely changed things for the worse," says Brian Fallon, MD, professor of psychiatry at Columbia University and the co-author of Phantom Illness: Recognizing, Understanding and Overcoming Hypochondria (1996). So far, no studies have been conducted on just how hypochondriacs use the Internet, Fallon says. But the phenomenon is common enough to have a snappy name -- "cyberchondria."
Lawrence Hrubes

Passing My Disability On to My Children - The New York Times - 0 views

  • Occasionally, I come across the term “designer baby,” and I am reminded that some parents now have the option to screen or modify the genes of their unborn children to ensure or avoid certain traits. It always gives me a feeling of unease. Obviously, I did not take this route — partly because, at least with my son, I never had to actually make the decision. My third child, Eliza, was a late midlife accident. I chose to have her despite the possibility she would have XLH, but would I have made the same decision in a planned pregnancy or if given a choice much earlier in the process? I can’t help suspecting that because of advances in genetic mapping, genetic testing, the sheer range of prenatal choices, chances are that in a generation or two, there will be no one in the world who has XLH, no one who looks like me or my children — at least not in the so-called developed world — and I don’t know how to feel about that.
Lawrence Hrubes

What's Behind Big Science Frauds? - NYTimes.com - 3 views

  • Remember that study showing vaccines were linked to autism? The time scientists claimed to have cloned human embryonic stem cells? Or that simple, easy way that was supposed to revolutionize the creation of such stem cells?Those were all frauds published in the world’s top scientific journals — The Lancet, Science and Nature. The vaccine scare has been associated with a surge in cases of measles, some of them deadly.Every day, on average, a scientific paper is retracted because of misconduct. Two percent of scientists admit to tinkering with their data in some kind of improper way. That number might appear small, but remember: Researchers publish some 2 million articles a year, often with taxpayer funding. In each of the last few years, the Office of Research Integrity, part of the United States Department of Health and Human Services, has sanctioned a dozen or so scientists for misconduct ranging from plagiarism to fabrication of results.
Lawrence Hrubes

FDA Ponders Putting Homeopathy To A Tougher Test : Shots - Health News : NPR - 0 views

  • In 1988, the Food and Drug Administration decided not to require homeopathic remedies to go through the same drug-approval process as standard medical treatments. Now the FDA is revisiting that decision. It will hold two days of hearings this week to decide if homeopathic remedies should have to be proven safe and effective.
Lawrence Hrubes

Map Reveals The Distinctive Cause Of Death In Each State : Shots - Health News : NPR - 0 views

  • There's no getting around the strangeness of a map that shows the most distinctive cause of death in each of our 50 states and the District of Columbia. In Texas, it's tuberculosis. In Maine, it's the flu. And in Nevada, it's the ominous "legal intervention." But what does it mean to label a cause of death distinctive?
Lawrence Hrubes

My Great-Great-Aunt Discovered Francium. And It Killed Her. - NYTimes.com - 0 views

  • There is a common narrative in science of the tragic genius who suffers for a great reward, and the tale of Curie, who died from exposure to radiation as a result of her pioneering work, is one of the most famous. There is a sense of grandeur in the idea that paying heavily is a means of advancing knowledge. But in truth, you can’t control what it is that you find — whether you’ve sacrificed your health for it, or simply years of your time.
  • How quickly an element decayed and how it did so — meaning which of its component parts it shed — became the focus of researchers in radioactivity. Apart from purely scientific insights, there was a hope that radiation could lead to something marvelous. X-rays, a kind of radiation discovered by Wilhelm Roentgen and produced by accelerated electrons, had already been hailed as a major medical breakthrough and, in addition to showing doctors their patients’ insides, were being investigated as a treatment for skin lesions from tuberculosis and lupus. In her 1904 book “Investigations on Radioactive Substances,” Marie Curie wrote that radium had promise, too — diseased skin exposed to it later regrew in a healthy state. Radium’s curious ability to destroy tissue was being turned against cancer, with doctors sewing capsules of radium into the surgical wounds of cancer patients (including Henrietta Lacks, whose cells are used today in research). This enthusiasm for radioactivity was not confined to the doctor’s office. The element was in face creams, tonics, even candy. According to the Encyclopaedia Britannica article that Curie and her daughter wrote on radium in 1926, preliminary experiments suggested that radium could even improve the quality of soil.
  • Perhaps the most tragic demonstration of this involved workers at the United States Radium Corporation factory in Orange, N.J., which in 1917 began hiring young women to paint watch faces with glow-in-the-dark radium paint. The workers were told that the paint was harmless and were encouraged to lick the paintbrushes to make them pointy enough to inscribe small numbers. In the years that followed, the women began to suffer ghoulish physical deterioration. Their jaws melted and ballooned into masses of tumors larger than fists, and cancers riddled their bodies. They developed anemia and necrosis. The sensational court case started — and won — by the dying Radium Girls, as they were called, is a landmark in the history of occupational health. It was settled in June 1928, four months before Marguerite Perey arrived at the Radium Institute to begin a 30-year career of heavy exposure to radiation.
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  • We know now that alpha and beta particles emitted in radiation attack DNA and that the mutations they cause can lead to cancer. Ingested radioactive elements can concentrate in the bones, where they continue their decay, in effect poisoning someone for as long as that person lives. By the time Perey made her discovery, she was already heavily contaminated. She spent the last 15 years of her life in treatment for a gruesome bone cancer that spread throughout her body, claiming her eyesight, pieces of her hand and most of the years in which she had planned to study francium. As the disease progressed, she warned her students of the horrible consequences of radiation exposure. Francis, my grandfather, says he recalls hearing that when she walked into labs with radiation counters in her later years, they would go off.
  • Over the years, historians have pondered what drove the Curies to throw caution so thoroughly to the wind. Perhaps it was inconceivable to them that the benefits of their research would not outweigh the risks to themselves and their employees. In a field in which groundbreaking discoveries were being made and the competition might arrive there first, speed was put above other concerns, Rona noted. But you almost get the impression that in the Curie lab, dedication to science was demonstrated by a willingness to poison yourself — as if what made a person’s research meaningful were the sacrifices made in the effort to learn something new.
Lawrence Hrubes

What If We Lost the Sky? - NYTimes.com - 0 views

  • What is the sky worth? This sounds like a philosophical question, but it might become a more concrete one. A report released last week by the National Research Council called for research into reversing climate change through a process called albedo modification: reflecting sunlight away from earth by, for instance, spraying aerosols into the atmosphere. Such a process could, some say, change the appearance of the sky — and that in turn could affect everything from our physical health to the way we see ourselves. If albedo modification were actually implemented, Alan Robock, a professor of environmental sciences at Rutgers, told Joel Achenbach at The Washington Post: “You’d get whiter skies. People wouldn’t have blue skies anymore.” And, he added, “astronomers wouldn’t be happy, because you’d have a cloud up there permanently. It’d be hard to see the Milky Way anymore.”
  • Losing the night sky would have big consequences, said Dacher Keltner, a psychology professor at the University of California, Berkeley. His recent work looks at the health effects of the emotion of awe. In a study published in January in the journal Emotion, he and his team found that people who experienced a great deal of awe had lower levels of a marker of inflammation that has been linked to physical and mental ailments. One major source of awe is the natural world. “When you go outside, and you walk in a beautiful setting, and you just feel not only uplifted but you just feel stronger,” said Dr. Keltner, “there’s clearly a neurophysiological basis for that.” And, he added, looking up at a starry sky provides “almost a prototypical awe experience,” an opportunity to feel “that you are small and modest and part of something vast.”
markfrankel18

The UK Wants To Blacklist Homeopathy | IFLScience - 0 views

  • Ministers in the U.K. are considering banning homeopathy from the treatments that can be prescribed by doctors working for the National Health Service (NHS). At the moment, the NHS spends £4 million ($6 million) on homeopathic prescriptions and hospitals every year
  • "Given the finite resources of the NHS, any spending on homeopathy is utterly unjustifiable. The money spent on these disproven remedies can be far better spent on treatments that offer real benefits to patients," Simon Singh, founder of the Good Thinking Society, said in a statement.
  • The positive effects from homeopathy come exclusively from the placebo effect, a physiological response to a harmless substance that leads to a reduction in symptoms from an ailment
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  • gnorance is not a fundamental tenant of experiencing the placebo effect, though.
  • Another issue with homeopathy is that the patients are not informed of what homeopathy is and how the placebo effect works. In 2012, the UK Science and Technology Committee addressed the ethics of it.
Lawrence Hrubes

When A Tattoo Literally Means Life Or Death : Shots - Health News : NPR - 2 views

  • The tattoo stretched across the man's chest. It said "Do Not Resuscitate." His signature was tattooed at the end. "We were shocked," remembers Holt. "We didn't know what to do." The tattoo, and the hospital's decision about what it required of them, has set off a conversation among doctors and medical ethicists around the country about how to express one's end-of-life wishes effectively, and how policymakers can make it easier.
markfrankel18

Mining Books To Map Emotions Through A Century : Shots - Health News : NPR - 0 views

  • "In 1941, sadness is at its peak," Bentley says.
  • Which brings us to the most surprising finding of the study: We think of modern culture — and often ourselves — as more emotionally open than people in the past. We live in a world of reality television and blogs and Facebook — it feels like feelings are everywhere, displayed to a degree that they never were before. But according to this research, that's not so.
Lawrence Hrubes

A New Form of Stem-Cell Engineering Raises Ethical Questions - The New York Times - 0 views

  • As biological research races forward, ethical quandaries are piling up. In a report published Tuesday in the journal eLife, researchers at Harvard Medical School said it was time to ponder a startling new prospect: synthetic embryos.In recent years, scientists have moved beyond in vitro fertilization. They are starting to assemble stem cells that can organize themselves into embryolike structures.Soon, experts predict, they will learn how to engineer these cells into new kinds of tissues and organs. Eventually, they may take on features of a mature human being.
Lawrence Hrubes

The placebo effect: A new study underscores its remarkable power - The Globe and Mail - 0 views

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    "But according to new research, the therapeutic effects of a placebo are so powerful that an inert pill has a good chance of reducing symptoms - even if patients know they are taking a dummy pill."
Lawrence Hrubes

How Language Seems To Shape One's View Of The World : Shots - Health News : NPR - 1 views

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    ""When Nabokov started translating it into Russian, he recalled a lot of things that he did not remember when he was writing it in English, and so in essence it became a somewhat different book," Pavlenko says."
Lawrence Hrubes

Ben Goldacre: Battling bad science | Video on TED.com - 0 views

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    "Every day there are news reports of new health advice, but how can you know if they're right? Doctor and epidemiologist Ben Goldacre shows us, at high speed, the ways evidence can be distorted, from the blindingly obvious nutrition claims to the very subtle tricks of the pharmaceutical industry. Ben Goldacre unpicks dodgy scientific claims made by scaremongering journalists, dubious government reports, pharmaceutical corporations, PR companies and quacks."
Lawrence Hrubes

Want To Read Others' Thoughts? Try Reading Literary Fiction : Shots - Health News : NPR - 0 views

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    "Your ability to "read" the thoughts and feelings of others could be affected by the kind of fiction you read. That's the conclusion of a study in the journal Science that gave tests of social perception to people who were randomly assigned to read excerpts from literary fiction, popular fiction or nonfiction."
Lawrence Hrubes

Mapping Emotions On The Body: Love Makes Us Warm All Over : Shots - Health News : NPR - 0 views

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    "When a team of scientists in Finland asked people to map out where they felt different emotions on their bodies, it found that the results were surprisingly consistent, even across cultures."
Lawrence Hrubes

Chinese teacher wakes up after stroke speaking English but no Chinese | Daily Mail Online - 2 views

  • However, she is not the only person to wake up from a coma speaking another language.Australian Ben McMahon woke up able to speak Mandarin after being involved in a car accident, while a 13-year-old Croatian girl woke up having replaced her fluency in her native language with speaking German. There was also the case of a U.S. navy veteran was found unconscious in a motel room who had no recollection of who he was and woke up speaking fluent Swedish. A Queensland Brain Institute neuroscientist suggested a possible explanation last year. Dr Pankaj Sah said the brain was made up of different circuits - which assist in language, breathing, speaking and thinking - similar to electronic circuits.According to him, it is possible in Ben's case that the parts of the brain which recalled English were damaged in the crash and those that retained Mandarin were activated when the 22-year-old woke up.Whether this is what happened to Ms Jieyu is not known. More commonly, people are known to have woken up with a different accent, like in the case of Kath Locket, who was born and bred in Stafford. But after she was rushed into hospital unable to speak or swallow, she developed a strong accent which was distinctly European.  WHAT IS FOREIGN ACCENT SYNDROME?
Diana Shafran

Negative Emotions Are Key to Well-Being - 0 views

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    Feeling sad, mad, critical or otherwise awful? Surprise: negative emotions are essential for mental health. In fact, anger and sadness are an important part of life, and new research shows that experiencing and accepting such emotions are vital to our mental health. Attempting to suppress thoughts can backfire and even diminish our sense of contentment. "Acknowledging the complexity of life may be an especially fruitful path to psychological well-being," says psychologist Jonathan M. Adler of the Franklin W. Olin College of Engineering.
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