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It's easy to sneer at the placebo effect, or to feel ashamed of it when you're its victim. And that's precisely why I found Felix Salmon's piece revelatory, because instead of sneering at the placebo effect of fancy wine, its marketing, and its slightly higher prices, he thinks we should take advantage of it. If the placebo effect makes us happy, why not take advantage of that happiness?

n a recent article for the Atlantic, David H. Freedman argues that there's virtually no scientific evidence that alternative medicine (anything from chiropractic care to acupuncture) has any curative benefit beyond a placebo effect. And so many scientists are outraged that anyone takes alternative medicine seriously. However, there is one area where alternative medicine often trumps traditional medicine: stress reduction. And stress reduction can, of course, make a huge impact on people's health. The Atlantic article quotes Elizabeth Blackburn, a biologist at the University of California at San Francisco and a Nobel laureate. “We tend to forget how powerful an organ the brain is in our biology,” Blackburn told me. “It’s the big controller. We’re seeing that the brain pokes its nose into a lot of the processes involved in these chronic diseases. It’s not that you can wish these diseases away, but it seems we can prevent and slow their onset with stress management.” Numerous studies have found that stress impairs the immune system, and a recent study found that relieving stress even seems to be linked to slowing the progression of cancer in some patients. Perhaps not surprisingly, a trip to the chiropractor or the acupuncturist is much more likely to reduce your stress than a trip to the doctor. If anything, a trip to the doctor makes you more anxious.

A little more than 40 years ago, a partially functioning brain would not have gotten in the way of organ donation; irreversible cardiopulmonary failure was still the only standard for determining death. But during the 1970s, that began to change, and by the early 1980s, the cessation of all brain activity — brain death — had become a widely accepted standard. In the transplant community, brain death was attractive for one particular reason: The bodies of such donors could remain on respirators to keep their organs healthy, even during much of the organ-removal surgery. Today, the medical establishment, facing a huge shortage of organs, needs new sources for transplantation. One solution has been a return to procuring organs from patients who die of heart failure. Before dying, these patients are likely to have been in a coma, sustained by a ventilator, with very minimal brain function — a hopeless distance from what we mean by consciousness. Still, many people, including some physicians, consider this type of organ donation, known as “donation after cardiac death” or DCD, as akin to murder.

Ethical questions The surgeon’s work was hailed as a game-changer in regenerative medicine when, in 2011, he implanted a plastic artificial trachea, using bioengineered stem cells, into a patient whose own windpipe had been damaged. Over the next three years, he carried out seven more synthetic trachea implantations — two more at the Karolinska, one in Illinois and four in Russia, where he heads a tissue engineering project. Six of the eight patients have died (from causes unrelated to the transplants, Macchiarini says), and one has been in intensive care since the procedure.

When, at the end, the Vatican committee asked if I had anything more to say, I blurted out that as much as her survival, thus far, was remarkable, I fully expected her to relapse some day sooner or later. What would the Vatican do then, revoke the canonization? The clerics recorded my doubts. But the case went forward and d’Youville was canonized on Dec. 9, 1990.