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Nathan Goodyear

[Role of glutamate and excitotoxicity in neurologi... [Rev Neurol (Paris). 1996] - PubM... - 0 views

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    nice abstract on the basic physiologic role of glutamate excitotoxicity
Nathan Goodyear

The role of excitotoxicity in neurodegenerative di... [Pharmacol Ther. 1999] - PubMed r... - 0 views

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    excitotoxicity and contribution to neurodegenerative disease
Nathan Goodyear

Pictorial Review of Glutamate Excitotoxicity: Fundamental Concepts for Neuroimaging -- ... - 0 views

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    Very heavy, but good read on glutamate excitotoxicity
Nathan Goodyear

Bioenergetic and oxidative stress in neurodegenera... [Life Sci. 1995] - PubMed result - 0 views

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    impaired mitochondrial function, oxidative stress and neurodegenerative disease
Nathan Goodyear

Microglial cells in neurodegenerative disorders. [Folia Neuropathol. 2005] - PubMed result - 0 views

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    nice article on microglial cells and how they contribute to Parkinson's, Alzheimer's, and other neurodegenerative diseases
Nathan Goodyear

The role of copper in neurodegenerative disease. [Neurobiol Dis. 1999] - PubMed result - 0 views

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    Copper imbalance contributes to development of Alzheimer's disease
Nathan Goodyear

Mitochondrial pathobiology in Parkinson's disease ... [J Alzheimers Dis. 2010] - PubMed... - 0 views

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    mitochondria and contribution to neurodegenerative diseases, Parkinson's disease and ALS
Nathan Goodyear

Mitochondria: a therapeutic target in neurodegener... [Biochim Biophys Acta. 2010] - Pu... - 0 views

  • mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
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    mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
Nathan Goodyear

Oxidative stress and neurotoxicity. [Chem Res Toxicol. 2008] - PubMed result - 0 views

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    Great article on how oxidative stress, and thus mitochondrial dysfunction, are at the core of neurodegenerative diseases
Nathan Goodyear

Mitochondrial DNA damage and repair in neurodegene... [DNA Repair (Amst). 2008] - PubMe... - 0 views

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    mitochondria dysfunction at core of aging and neurodegenerative disease
Nathan Goodyear

Mitochondria and neurodegeneration. [Biosci Rep. 2007] - PubMed result - 0 views

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    mitochondria dysfunction and contribution to neurodegenerative disease
Nathan Goodyear

Mitochondria, metabolic disturbances, oxidative st... [J Neurol Sci. 2007] - PubMed result - 0 views

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    Great article on CoQ10, mitochondrial function, the kynurenine system and neurodegenerative diseases
Nathan Goodyear

Ubiquinone (coenzyme q10) and mitochondria in oxid... [Biol Signals Recept. 2001 May-Au... - 0 views

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    Very good discussion on CoQ10, oxidative stress, and Parkinson's disease
Nathan Goodyear

Coenzyme Q10 reverses pathological phenotype and r... [Neurology. 2001] - PubMed result - 0 views

  • The authors conclude that muscle CoQ10 deficiency can be corrected by supplementation of CoQ10, which appears to stimulate mitochondrial proliferation and to prevent apoptosis.
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    CoQ10 supplementation shown to resolve familial CoQ10 deficiency
Nathan Goodyear

Mitochondrial dysfunction and oxidative damage in ... [J Bioenerg Biomembr. 2004] - Pub... - 0 views

  • he increasing evidence that Parkinson's disease is associated with abnormalities in the electron transport gene as well as oxidative damage
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    CoQ10 useful to improve mitochondrial function and thus treatment of neurodegenerative diseases
Nathan Goodyear

Coenzyme Q10 in the central nervous system and its... [Mol Aspects Med. 1997] - PubMed ... - 0 views

  • These findings suggest that coenzyme Q10 might be useful in treating neurodegenerative diseases.
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    CoQ10 useful in treating neurodegenerative diseases
Nathan Goodyear

Mitochondrial disorders. [Curr Opin Neurol. 2007] - PubMed result - 0 views

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    mitochondrial medicine and contribution to neurodegenerative diseases
Nathan Goodyear

Bioenergetic and antioxidant properties of coenzym... [Mol Biotechnol. 2007] - PubMed r... - 0 views

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    CoQ10 is antioxidant and is beneficial in atherosclerosis
Nathan Goodyear

Coenzyme Q10 and statins: biochemical and clinical... [Mitochondrion. 2007] - PubMed re... - 0 views

  • physicians should be aware of this drug-nutrient interaction and be vigilant to the possibility that statin drugs may, in some cases, impair skeletal muscle and myocardial bioenergetics.
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    Statins not good for those who have CoQ10 dysfunction
Nathan Goodyear

Mitochondrial medicine for aging and neurodegenera... [Neuromolecular Med. 2008] - PubM... - 0 views

  • This article discusses critical issues of mitochondria causing dysfunction in aging and neurodegenerative diseases, and discusses the potential of developing mitochondrial medicine, particularly mitochondrially targeted antioxidants, to treat aging and neurodegenerative diseases.
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    Great review of mitochondrial medicine to treat age-related and neurodegenerative disease
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