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Nathan Goodyear

Lupus: Mysterious Disease Holds Its Secrets Tight - 0 views

www.sciencemag.org/...689.summary

lupus disease

shared by Nathan Goodyear on 23 Mar 11 - No Cached
  • Nathan Goodyear on 23 Mar 11
     
    Nice read on how loss environment and immune dysfunction help lead to LUpus
Nathan Goodyear

Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role... - 0 views

www.jacionline.org/...abstract

sulforaphane nrf2 Th1 Th2

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    sulforaphane upregulates Th1 immunity; which aging shifts to Th2 dominance
Nathan Goodyear

The Th17/Treg imbalance in patients with acute cor... [Clin Immunol. 2008] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18294918

th17 treg inflammation cardiovascular disease

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  • Nathan Goodyear on 22 Mar 11
     
    The Th17/Treg imbalance in patients with acute coronary syndrome.
Nathan Goodyear

Th17: the third member of the effector T cell tril... [Curr Opin Immunol. 2007] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...17766098

th17 immune system inflammation

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  • Nathan Goodyear on 22 Mar 11
     
    Th17: the third member of the effector T cell trilogy.
Nathan Goodyear

IL-17 and Th17 Cells. [Annu Rev Immunol. 2009] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...19132915

Th17 immune system

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    Th17 cells play important role along with Th1 and Th2
Nathan Goodyear

Arch Intern Med -- Abstract: The Progressive Cost of Complications in Type 2 Diabetes M... - 0 views

archinte.ama-assn.org/...1873

health costs healthcare

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Per-person costs increased over baseline ($2033) by more than 50% ($1087) after initiation of cardiovascular drug therapy and/or use of a cardiologist, and by 360% ($7352) after a major cardiovascular event. Abnormal renal function increased diabetes treatment costs by 65% ($1337); advanced renal disease, by 195% ($3979); and end-stage renal disease, by 771% ($15,675)
  • Nathan Goodyear on 22 Mar 11
     
    Costs of "poor health"
Nathan Goodyear

Journal of Clinical Investigation -- Therapeutic potential of inhibition of t... - 0 views

www.jci.org/...1

NF-KappaB inflammation Cancer

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    NF-KappaB target of treatment of inflammation and Cancer
Nathan Goodyear

Journal of Clinical Investigation -- NF-κB: a key role in inflammatory diseases - 0 views

www.jci.org/...1

NF-KappaB inflammation Immune response

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    NF-KappaB in Immune response and inflammation
Nathan Goodyear

Function and Activation of NF-kappaB in the Immune System - Annual Review of Immunology... - 0 views

www.annualreviews.org/...annurev.iy.12.040194.001041

NF-KappaB Immune System

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    NF-KappaB and activation of the Immune System
Nathan Goodyear

Hypothalamic IKKbeta/NF-kappaB and ER stress link ... [Cell. 2008] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18854155

hypothalamus NF-KappaB inflammation ikkbeta

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Our results show that the hypothalamic IKKbeta/NF-kappaB program is a general neural mechanism for energy imbalance underlying obesity and suggest that suppressing hypothalamic IKKbeta/NF-kappaB may represent a strategy to combat obesity and related diseases
  • Nathan Goodyear on 22 Mar 11
     
    INflammation of hypothalamus through NF-KappaB leads to obesity and related diseases
Nathan Goodyear

NFkappaB-mediated metabolic inflammation in periph... [Cell Cycle. 2009] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...19633416

nfkappab mediated inflammation metabolic dysfunction

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • Nathan Goodyear on 22 Mar 11
     
    NF-KappaB mediated inflammation
Nathan Goodyear

Mechanism of IL-1β-Induced Increase in Intestinal Epithelial Tight Junction P... - 0 views

www.jimmunol.org/...5653.full

inflammation Gut NF-kappaB intestinal inflammatory conditions

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • The IL-1β-induced increase in intestinal epithelial tight junction (TJ) permeability has been postulated to be an important mechanism contributing to intestinal inflammation of Crohn’s disease and other inflammatory conditions of the gut
  • the role of myosin L chain kinase (MLCK)
  • IL-1β caused a progressive increase in MLCK protein expression.
  • ...1 more annotation...
  • The IL-1β-induced increase in MLCK mRNA transcription and subsequent increase in MLCK protein expression and Caco-2 TJ permeability was mediated by activation of NF-κB
  • Nathan Goodyear on 22 Mar 11
     
    How systemic inflammation comes from the gut
Nathan Goodyear

IN THIS ISSUE - The Journal of Immunology - 0 views

www.jimmunol.org/...5155.short

Immune system thymus immunity

shared by Nathan Goodyear on 22 Mar 11 - No Cached
  • t has been suggested that increased permeability of intestinal epithelial tight junctions (TJ) in these diseases is mediated by proinflammatory cytokines including IL-1β,
  • Al-Sadi et al. (p. 5653 ) hypothesized that myosin light chain kinase (MLCK), which is known to be important for intestinal TJ permeability, could mediate IL-1β-induced disruption of the epithelial barrier
  • Nathan Goodyear on 22 Mar 11
     
    Heavy article on immune system activation
Nathan Goodyear

Mechanisms of Edema Formation After Intracerebral Hemorrhage: Effects of Extravasated R... - 0 views

stroke.ahajournals.org/...2932

intracerebral hemorrhage brain edema

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • Nathan Goodyear on 21 Mar 11
     
    How the brain swells after intracerebral hemorrhage
Nathan Goodyear

Attention-Deficit/Hyperactivity Disorder and Urinary Metabolites of Organophosphate Pes... - 0 views

pediatrics.aappublications.org/...e1270

ADHD pesticide exposure Organophosphates

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • Nathan Goodyear on 21 Mar 11
     
    ADHD and pesticide exposure
Nathan Goodyear

EWG Report || BodyBurden 2 - The Pollution in Newborns - 0 views

www.ewg.org/...execsumm.php

pollution newborns bodyburden toxins toxicity

shared by Nathan Goodyear on 21 Mar 11 - Cached
  • Tests revealed a total of 287 chemicals in the group.
  • Of the 287 chemicals we detected in umbilical cord blood, we know that 180 cause cancer in humans or animals, 217 are toxic to the brain and nervous system, and 208 cause birth defects or abnormal development in animal tests
  • Nathan Goodyear on 21 Mar 11
     
    Body Burden - The Pollution in Newborns
Nathan Goodyear

Trends in Environmentally Related Childhood Illnesses -- Woodruff et al. 113 (3): 1133 ... - 0 views

pediatrics.aappublications.org/...1133

environmental toxins childhood disease

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • Nathan Goodyear on 21 Mar 11
     
    environmental toxins and childhood disease
Nathan Goodyear

1alpha,25-dihydroxyvitamin D3 interacts with curcu... [J Alzheimers Dis. 2009] - PubMed... - 0 views

www.ncbi.nlm.nih.gov/...19433889

Vitamin D3 Alzheimer's disease

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • 1,25D3 strongly stimulated Abeta phagocytosis and clearance while protecting against apoptosis
  • Nathan Goodyear on 21 Mar 11
     
    Vitamin D3 and Alzheimer's disease
Nathan Goodyear

Systemic Inflammation Is Associated with MCI and Its Subtypes: The Sydney Memory and Ag... - 0 views

content.karger.com/...produkte.asp

systemic inflammation cognitive impairment memory

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • point to a discrete impact of systemic inflammation on cognition.
  • Nathan Goodyear on 21 Mar 11
     
    inflammation leads to cognitive impairment
Nathan Goodyear

Methylmercury > Mercury Concentrations in Fish: FDA Monitoring Program - 0 views

www.fda.gov/...ucm191007.htm

mercury methylmercury concentrations fish

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • Mercury Concentrations in Fish
  • Nathan Goodyear on 21 Mar 11
     
    Mercury Concentrations in Fish
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