Melatonin might help in controlling weight gain and preventing heart diseases associated with obesity - 0 views
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Nathan Goodyear on 05 May 11Melatonin helps in weight loss
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Melatonin might help control weight gain and prevent heart disease associated with obesity - 0 views
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Melatonin helps weight loss and improves cardiovascular disease risk factors
Melatonin and Cortisol assessment of circadian shifts in astronauts before flight - Whitson - 2007 - Journal of Pineal Research - Wiley Online Library - 0 views
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Melatonin and Cortisol salivary testing by NASA
Efficacy of the concomitant administration of the pineal hormone melatonin in cancer immunotherapy with low-dose IL-2 in patients with advanced sol... - PubMed - NCBI - 0 views
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melatonin found to enhance the IL-2 anti-tumor activity in preliminary study.
PayPerView: A Randomized Study of Low-Dose Subcutaneous lnterleukin-2 Plus Melatonin versus Supportive Care Alone in Metastatic Colorectal Cancer Patients Progressing under 5-Fluorouracil and Folates - Karger Publishers - 0 views
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Percent survival at 1 year was significantly increased in patients treated with immunotherapy than in those treated with supportive care alone (9/25 vs. 3/25, p < 0.05) in study which suggests that low-dose subcutaneous IL-2 plus melatonin may be effective as a second-line therapy to induce tumor regression and to prolong percent survival at 1 year in metastatic colorectal cancer patients progressing under 5-FU and folates
Efficacy of Melatonin in the Immunotherapy of Cancer Using lnterleukin-2 | SpringerLink - 0 views
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Low dose IL-2 + high dose melatonin increases 1 year survival in the treatment of solid tumors in pilot study.
A phase II study of chemoneuroimmunotherapy with platinum, subcutaneous low-dose interleukin-2 and the pineal neurohormone melatonin (P.I.M.) as a ... - PubMed - NCBI - 0 views
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Low dose cisplatin, low dose IL-2 and high dose melatonin as effective as first line therapy in the treatment of melanoma
Immunotherapy with subcutaneous low dose interleukin-2 plus melatonin as salvage therapy of heavily chemotherapy-pretreated ovarian cancer - 0 views
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Small phase II pilot sutyd of advanced ovarian cancer, foud low dose IL-2 at 3 million IU/day X 6 days for 4 weeks preceded by 40 mg melatonin provides some benefit in advanced disease following at least 3 failed polychemotherapy regimens.
Immunotherapy with subcutaneous low-dose interleukin-2 and the pineal indole melatonin as a new... - Europe PMC Article - Europe PMC - 0 views
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study on melatonin and IL2 in cancer
Immunotherapy with low-dose interleukin-2 in association with melatonin as salvage therapy for metastatic soft tissue sarcomas - 0 views
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Study, again of advanced cancer, with previous failed chemotherapy found that melatonin plus low-dose IL-2 therapy stimulated lymphocyte production and provided a partial response and stable disease. No control group.
PREOPERATIVE NEUROIMMUNOTHERAPY WITH SUBCUTANEONS LOW-DOSE INTERLEUKIN-2 AND MELATONIN IN PATIENTS WITH GASTROINTESTINAL TUMORS - ITS EFFICACY IN PREVENTING SURGERY-INDUCED LYMPHOCYTOPENIA - 0 views
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Study of pre-operative IL-2 and melatonin versus control found an increase in the lymphocytes, T lymphocytes, and NK cell activity. Again, no toxicity reported.
A phase II study of neuroimmunotherapy with subcutaneous low-dose IL-2 plus the pineal hormone melatonin in untreatable advanced hematologic malign... - PubMed - NCBI - 0 views
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Abstract only here. Immunotherapy of IL-2 + melatonin provided lack of progression of 67% of patients included with a average duration of 21+ months in patients with untreatable advanced hematologic cancer. Again, no toxicities. Interesting, the survival time was similar to the previously reported survival times with the highly toxic high dose IL-2 therapy.
Abrogation of the Negative Influence of Opioids on IL-2 Immunotherapy of Renal Cell Cancer by Melatonin - Abstract - European Urology 2000, Vol. 38, No. 1 - Karger Publishers - 0 views
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only abstract available here to general public. Opiates suprress the immune system. This is an important point in the fight against cancer. Cancer is, in part, the result of signficant immune imbalance. In this study of patients with Renal Cell Cancer, melatonin + IL-2 was found to counter this immunosuppressive effect of morphine to increase partial response and to increase the 3 year survival.
Melatonin for the prevention and treatment of cancer - 0 views
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Wide benefits of melatonin in the battle against cancer: HIF-1alpha inhibitor, aromatase inhibitory, anti-angiogenesis, triggers apoptosis...
A randomized study of immunotherapy with low-dose subcutaneous interleukin-2 plus melatonin vs chemotherapy with cisplatin and etoposide as first-l... - PubMed - NCBI - 1 views
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Average progression-free time and percentage of patients alive at 1 year was significantly higher in those using IL-2 and melatonin compared to chemotherapy in aggressive NSCLC. Of note, in this study, they used a repeat cycle of IL-2 and MLT as well as a once/week maintenance IL-2 and MLT.
Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland - 0 views
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dopamine inhibits melatonin production and release disrupting sleep.
View of Understanding the role of melatonin in cancer metabolism | melatonin Research - 0 views
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