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This study shows high dose vitamin C infusion decreased postoperative pain during the first 24 h and reduced morphine consumption in the early postoperative period.

only abstract available here to general public.  Opiates suprress the immune system.  This is an important point in the fight against cancer. Cancer is, in part, the result of signficant immune imbalance.  In this study of patients with Renal Cell Cancer, melatonin + IL-2 was found to counter this immunosuppressive effect of morphine to increase partial response and to increase the 3 year survival.

Vitamin C at a low dose 50 mg/kg reduced post-op pain and morphine requirements in first 24 hours.

Vitamin C associated with reduced post-op pain and less need for post-op morphine.

Meta-analysis of 7 studies finds improvement in post-op pain and reduction in morphine.

Glucose, and especially fructose shown to antagonize opioid receptors. This negatively effects pain control. Novel concept: pain control requires dietary fructose restriction.

great study that shows how BPA exposure has its largest impact on the mesolimbic/dopamine system during organogenesis and lactation periods.

Dexamethasone for nausea

Good review of meds for nausea.

Opiates are outright immunosuppressive.

opioids use during immunotherapy is associated with early progression, potentially representing a predictive factor for PFS and negatively influencing OS as well.