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fnfdoc

Friends And Family Doctor | Health Blog - 0 views

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    Staying in shape can be really tough in today's world. We, at fnfdoc.com, join hands with the community to learn more about health and wellness. We talk about the ways to achieve optimum strength and fitness. Let's learn more about the nature of disease. Because you can only fight what you understand.
Nathan Goodyear

JPM | Free Full-Text | Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort - 0 views

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    fitness trackers not reliable at all in the measure of calories burned.
Nathan Goodyear

A cross-sectional study of different patterns of oral contraceptive use among premenopausal women and circulating IGF-1: implications for disease risk - 0 views

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    Birth control pills were found to reduce IGF-1 levels in the short term and long term.  Those that had used birth control pills had lower IGF-1 levels compared to those that had never used birth control pills.  This fits with the current knowledge that oral estrogen reduces HGH and IGF-1.  Those were in post-menopausal women, but this is in pre-menopaus women.  This has implications on health, weight, disease...
Nathan Goodyear

Inflammatory responses to trivalent influenza virus ... [Vaccine. 2011] - PubMed - NCBI - 0 views

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    This article's conclusion fits the definition of insane. This article found that the flu vaccine in pregnant women found significant increased CRP, TNF-alpha, and IL-6 inflammatory biomarkers.  It is well recognized the impact of inflammation on health and in this case the developing baby.   For example, preeclampsia and preterm birth are inflammatory conditions.  Yet, ACOG has made recommmendations for all pregnant women to get the flu vaccine?!?! Here is their conclusion: "However, further research is needed to confirm that the mild inflammatory response elicited by vaccination is benign in pregnancy".  Take home, you are being studied to see the effects of the flu vaccine on you, if you are pregnant, and your developing child.  And who decides what "mild" is anyways.  If you develop preeclampsia and delivery early, where is the "mild" in that?
Nathan Goodyear

The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence - 0 views

  • studies have demonstrated that the shortest telomeres are causal of reduced cell viability
  • a stable and enforced expression of telomerase leads to an improved health-span, accompanied by an extension of lifespan
  • TA-65 influences the percentage of cellular short telomeres through the activation of telomerase
  • ...17 more annotations...
  • TA-65 administration during 4 months significantly improved the capacity to uptake glucose after a glucose pulse
  • liver protective action of TA-65
  • A disadvantage of mTERT potentiation could be associated to its capacity to favor proliferation of cancerous cells in murine models
  • TA-65 treated mice presented a similar incidence of malignant cancers at time of death, with a tendency to show decreased sarcomas and slightly increased lymphomas
  • We demonstrate here that TA-65 leads to a significant rescue of short telomeres through telomerase activation
  • TA-65 treatment increases proliferation and mobilization potential of mouse keratinocytes in vitro, a situation mimicking telomerase overexpression
  • TAT2, a similar molecule, have beneficial effects in the activation of CD8+ T lymphocytes from HIV-infected patients where they observe an increase of the proliferative potential and enhancement of cytokine/chemokine production
  • TA-65 resulted in a similar rescue of short telomeres in leukocytes post-treatment as observed with humans, most likely through an activation of telomerase
  • we observe that TA-65 lead to 10 fold increase of telomerase RNA levels in the liver of treated mice comparing to the non-treated same-age cohorts
  • TA-65 regulates telomerase at the transcription level, probably through the regulation of the MAPK pathway
  • TA-65 dependent telomerase activation results in a better organ fitness as demonstrated by the improved scores at the glucose tolerance test and insulin levels at fasting
  • TA-65 supplemented mice also present modest enhancement of the subcutaneous and epidermal thickness, as well as higher bone density, representative of an overall fitness status improvemen
  • TA-65 treated mice present higher levels of RBC and hemoglobin comparing to the control cohorts
  • improved health-span of TA-65 treated mice is not accompanied by increased cancer incidence, which may be related to the fact that TERT levels are very modestly increased in all tissues tested except for the liver
  • systemic telomerase overexpression from the germline leads to protection from aging associated pathologies
  • similar situation could be mimicked expressing telomerase late in life in a telomerase deficient background
  • we observed a higher proliferation rate and a partial protection from cell death in some tissues of TA65 treated mice
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    TA-65 shown to increase telomerase activity, and thus telomere length of short telomeres, in mouse study.  
wheelchairindia9

Wrist Brace with Double Lock - 0 views

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    Tynor Wrist Brace with Double Lock Wrist brace with double lock is designed to support, protect and partially immobilize the wrist. It compresses the area and retain the body heat to allay local pain and inflammation. Extra grip. Extra porous Controlled compression. Easy application. Tynor Wrist Brace with Double Lock Features High quality, striped elastic webbing Strong and durable Porous and comfortable High modulus of elasticity- Retains shape and size for a long time. Excellent compressive strength, better support Hook loop Double locking Easy to apply and remove Ensures optimal compression Better fitting and universal sizing. Tynor Wrist Brace with Double Lock Measurements Measure circumference evenly around the wrist joint
wheelchairindia9

Tynor Wrist Splint Ambidextrous - 0 views

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    Tynor Wrist Splint Ambidextrous Applications Early cast removal. Fracture management. Post surgical protection and rehabilitation. Rheumatic disease of the wrist and arthritic hand positioning. Bursitis, Tendonitis, Tensosynovitis. Psychological assurance. Post extensor tendon repair surgery. Conservative management of keinbock's disease. Sprains and strains. Tynor Wrist Splint Ambidextrous Features Customizable Splints. Controlled compression. Anatomical thumb opening. Fits both left and right hand. Tynor Wrist Splint Ambidextrous Measurements Measure circumference at a distance 6" from the wrist along the arm
wheelchairindia9

Tynor Cervical Collar Hard Adjustable - 0 views

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    Tynor Cervical Collar Hard Adjustable Cervical Collar Hard Adjustable is used for supporting, immobilizing or adjusting the neck in the flexion, extension, or hyperextension position. Recommended where a rigid immobilization of the cervical region is required. Anatomical shape. Comfortable edge padding. Adjustable height. Slight weight. Latex free. Tynor Cervical Collar Hard Adjustable Features Edge padding by ethafoam Better cushioning and comfort long functional life Light in weight No leaching no allergy Better cushioning and comfort Anatomically designed with height adjustment Ensures perfect fitting Improves immobilsation Enhances comfort Perforated Better ventilation Enhances comfort Better patient compliance. High quality PE Sheet Ensures rigid support Long life of the collar Improves aesthetics. Tynor Cervical Collar Hard Adjustable Measurements Measure distance between edge of sternum and lower jaw with neck in extension position.
wheelchairindia9

Tynor Elastic Wrist Splint - 0 views

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    Tynor Elastic Wrist Splint Tynor Elastic Wrist Splint is designed to immobilize and provide firm support to hand and wrist in various orthopedic conditions. It maintains the wrist in the dorsi flexion functional position while allowing full range of motion to fingers and thumb. The splint can be removed to permit, therapy sessions, washing and hygiene. Malleable Splint. Perfect Immobilization Controlled compression. Anatomical thumb opening. Tynor Elastic Wrist Splint Features High quality Elastic Webbing Strong and durable Porous and comfortable High modulus of elasticity-- Retains shape and size for a long time. Removable, Aluminum Splints Customized fitting Required degree of dorsi-flexion can be achieved Very good grip and immobilization Hook loop closures Easy to apply and remove Ensures optimal compression. Built in opening for thumb abduction Better pain relief and healing. Thumb remains relaxed, no fatigue mproves comfort Tynor Elastic Wrist Splint Measurements Measure circumference evenly around the wrist
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