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Nathan Goodyear

Effects of Age and Sedentary Lifestyle on Skeletal Muscle NF-κB Signaling in Men - 0 views

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    Aging and sedentary lifestyle associated with muscle loss through NF-KappaB activation.
Nathan Goodyear

PLOS Medicine: Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mor... - 0 views

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    no surprise that sedentary lifestyle associated with decreased lifespan. Exercise is beneficial in normal weight and obese individuals.  Also of note, one does not need to train for a marathon to see the health benefits.  Exercise is more about intensity than it is about duration/frequency.
Nathan Goodyear

Physical activity and all-cause mortality across levels of overall and abdominal adipos... - 0 views

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    Mortality increased by sedentary lifestyle.  The risk is on par with that of BMI and waist circumference.
Nathan Goodyear

Effect of resistance exercise on muscle steroidogenesis | Journal of Applied Physiology - 0 views

  • skeletal muscle cell cultures incubated with DHEA produced testosterone in a DHEA dose-dependent manner
  • Muscle joins a growing list of tissues found to be capable of steroidogenesis
  • testosterone appears to have a role in the maintenance of muscle mass in women, although the importance of this role has not yet been fully established.
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  • Circulating testosterone concentrations are generally elevated following a bout of resistance exercise in men (24, 31, 46, 52), whereas findings for the effect of resistance exercise on circulating testosterone in women are equivocal, with increases (10, 42) and no changes observed (22, 31)
  • swimming (51) and treadmill running (2) can significantly increase muscle testosterone concentrations in male and female rats
  • This upregulation of muscle testosterone in rats appears, at least in part, to be due to an increase in 3β-HSD and 17β-HSD type 1 expression
  • The primary finding in this study was that muscle steroidogenesis (i.e., testosterone production) in highly resistance-trained humans was not affected by an acute bout of heavy resistance exercise
  • A secondary finding was that the apparent molecular mass of 17β-HSD type 3 was increased following a single bout of heavy resistance exercise.
  • No differences were found for muscle testosterone or steroidogenic enzyme (17β-HSD type 3 and 3β-HSD types 1 and 2) concentrations between sexes or in response to resistance exercise
  • In conclusion, heavy resistance exercise did not induce changes in muscle steroidogenesis as measured by muscle concentrations of testosterone, 3β-HSD types 1 and 2, and 17β-HSD type 3 in highly resistance-trained young men and women.
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    Resistance exercise did not increase muscle concentrations of Testosterone in men or women.  The individuals in this study were actively training.  These were not sedentary individuals.
indiacardiacsurg

Dr Rajiv Parakh Talk about 3 Things You Can Do Today to Prevent Apoplexy - 0 views

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    Vascular Surgeon in Medanta Gurugram explains "Living a sedentary way of life and consuming the wrong forms of meals puts people at a more risk of having apoplexy." The expert goes on to say that eating a healthy diet and getting sufficient workout routines are two of the most important things people can do to save apoplexy.
Nathan Goodyear

Reevaluation of the protein requirement in young men with the indicator amino acid oxid... - 0 views

  • the mean and population-safe protein requirements were estimated to be 0.93 and 1.2 g · kg−1 · d
  • diet containing 0.90 g · kg−1 · d−1 was at or above physiologic protein requirements for sedentary men
  • The current EAR recommendation and RDA for protein are 0.66 and 0.80 g · kg−1 · d−1, respectively. We believe that these recommendations are tentative because no long-term studies have suggested that these values would maintain nitrogen balance along with lean body mass, muscle mass, serum protein concentrations, immunity, functional capacity etc
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  • a series of long-term balance studies (67-69) showed that intake of the proposed safe allowance of 0.57 g (70) egg protein resulted in negative nitrogen balance, loss of lean body mass, and deteriorating serum protein and transferase values unless additional energy or nonessential nitrogen was supplied
  • The results of the present study suggest that the current EAR recommendations (0.66 g · kg−1 · d−1) and RDA (0.80 g · kg−1 · d−1) for protein are underestimated at 29% and 33%, respectively
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    study looked at protein requirements in 8 "healthy" men.  This study pointed to 1.2 g/kg/day as an appropriate daily dietary protein intake for healthy men.  This far exceeds levels per RDA.
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