Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multi... - 0 views
-
Patients received a median of six doses of nivolumab
-
four of the first 12 patients had partial responses
-
Nine (24% [95% CI 15–33]) of 37 patients achieved a response (seven partial responses and two complete responses
- ...16 more annotations...
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde... - 0 views
-
Hydroxyl radicals cause oxidative damage to cells because they unspecifically attack biomolecules [22] located less than a few nanometres from its site of generation and are involved in cellular disorders such as neurodegeneration [23, 24], cardiovascular disease [25], and cancer [26, 27].
-
It is generally assumed that in biological systems is formed through redox cycling by Fenton reaction, where free iron (Fe2+) reacts with hydrogen peroxide (H2O2) and the Haber-Weiss reaction that results in the production of Fe2+ when superoxide reacts with ferric iron (Fe3+)
-
other transition-metal including Cu, Ni, Co, and V can be responsible for formation in living cells
- ...20 more annotations...
Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer... - 0 views
-
More than half of cancer patients are treated with IR at some point during their treatment
-
fractionation schedule is the delivery of 1.8–2.0 Gy per day, five days per week
-
Nuclear DNA is the primary target of IR; it causes DNA damage (genotoxic stress) by direct DNA ionization
- ...121 more annotations...
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatm... - 0 views
1 - 15 of 15
Showing 20▼ items per page