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Nathan Goodyear

Histidine suppresses food intake through its conversion into neuronal histamine. - PubM... - 0 views

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    neuronal histidine to histamine conversion suppresses appetite via leptin feedback signaling.  
Nathan Goodyear

Gut Microbe-Mediated Suppression of Inflammation-Associated Colon Carcinogenesis by Lum... - 0 views

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    Only abstract available here: Gut bacteria, lactobacillus reuteri, could be the key to colon cancer prevention through inflammation control.  What is fascinating is how the gut bacteria influenced epigenetic expression of histidine decarboxylase to increase histamine production.
Nathan Goodyear

Histamine and histamine intolerance - 0 views

  • Histamine intolerance can develop through both increased availability of histamine and impaired histamine degradation
  • increased availability may be an endogenous histamine overproduction caused by allergies, mastocytosis, bacterias, gastrointestinal bleeding, or increased exogenous ingestion of histidine or histamine by food or alcohol
  • Other biogenic amines, such as putrescine, may also be involved in displacing histamine from its mucosal mucine linkage, which results in an increase of free absorbable histamine in circulation
  • ...2 more annotations...
  • the main cause of histamine intolerance is an impaired enzymatic histamine degradation caused by genetic or acquired impairment of the enzymatic function of DAO or HNMT
  • The main enzyme for metabolism of ingested histamine is diamine oxidase (DAO)
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    good discussion of histamine and histamine intolerance.  All centers around diamine oxidase function (DAO).
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