Interleukin‐2 enhances the natural killer cell response to Herceptin‐coated H... - 1 views
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administration of low‐dose IL‐2 results in expansion of a CD3– / CD56+ NK cell population in patients with advanced cancer
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approximately 20 % will overexpress theHer2 / neu proto‐oncogene
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In breast cancer, Her2 / neu overexpression is associated with a worse histologicalgrade, decreased relapse‐free and overall survival periods, and altered sensitivity to chemotherapeutic regimens
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Role of IL-2 in cancer immunotherapy: OncoImmunology: Vol 5, No 6 - 1 views
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IL-2 is one of the key cytokines with pleiotropic effects on the immune system
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IL-2 as “T-cell growth factor”
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approved for the treatment of metastatic renal cell carcinoma (1992) and later for metastatic melanoma (1998) by FDA
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Nutrients | Free Full-Text | Effect of Probiotics on Metabolic Outcomes in Pregnant Wom... - 0 views
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The gut microbial composition is altered during pregnancy
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probiotic supplements may contribute to the maintenance of bacterial diversity and glucose homeostasis in individuals with metabolic disturbances
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Assessment of four randomized controlled trials in this review involving 288 pregnant women with GDM found that a 6–8 week probiotic intervention did not improve FBG or LDL-cholesterol levels
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Review (4 studies) found that 6-8 weeks of probiotic therapy of pregnant women with gestational diabetes improved insulin resistance.
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Chemotherapy induces tumor immune evasion by upregulation of programmed cell ... - 0 views
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upregulation of glycolysis in cancer cells, with subsequent exhaustion of glucose in the microenvironment, leading to the death of T cells from starvation
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PD‐L1 expression promotes the production of interleukin 10, a cytokine involved in the death of activated T cells
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PD‐L1 expression in tumor tissue might lead to T‐cell exhaustion and unresponsiveness
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(PDF) Review Surgical Oncotaxis Excessive Surgical Stress and Postoperative Complicatio... - 0 views
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