Understanding and determining the etiology of auti... [Cell Mol Neurobiol. 2010] - PubM... - 0 views
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Worldwide, the rate of autism has been steadily rising.
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Genetic polymorphisms of cytochrome P450 enzymes have also been linked to autism, specifically CYP27B1 that is essential for proper vitamin D metabolism
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There are several environmental factors in concert with genetic susceptibilities that are contributing to this rise. Impaired methylation and mutations of mecp2 have been associated with autistic spectrum disorders, and related Rett syndrome.
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