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Nathan Goodyear

Medical Marijuana for Chronic Lymphocytic Leukemia | Marijuana Doctors - 0 views

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    Not a research article, but some interesting information
Nathan Goodyear

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition | Mol... - 0 views

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    Mouse study finds THC and CBD agonist reduce tumor growth, inhibit angiogenesis, induce apoptosis, and reduce metastasis. In addition, 91% of breast cancers in animal study expressed CB2 receptors.
Nathan Goodyear

Frontiers | Antitumor Effects of Cannabinoids in Human Pancreatic Ductal Adenocarcinoma... - 0 views

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    dose-dependent trigger of pancreatic cancer apoptosis in mouse model. They dosed up to 10 mg/kg at a ratio of THC:CBD of 1:6.
Nathan Goodyear

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in... - 0 views

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    combination of Gemzar and CBD increase survival in mouse model Mechanism is through GPR55 signaling.
Nathan Goodyear

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352507/#:~:text=THC%20has%20been%20shown%... - 0 views

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    THC induces apoptosis via ceramide de novo synthesis
Nathan Goodyear

Cannabis, a complex plant: different compounds and different effects on individuals - PMC - 2 views

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    It doesn't have any side-effects, you just need to buy it somewhere on a reliable website. As for me, I can give you a little advice, if you have some free time, read an article about the CBD for anxiety https://askgrowers.com/blog/best-disposable-cbd-vape-pens-2022-list-of-top-brands-and-buying-guide and choose something there. It will definitely help much more than any other resources.
Nathan Goodyear

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stre... - 0 views

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    Describes the mechanism by which THC induces autophagy cell death of glioma cells.
Nathan Goodyear

A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma | Molecu... - 0 views

  • Δ9-Tetrahydrocannabinol (THC; Supplementary Fig. 1), the main active component of the hemp plant Cannabis sativa
  • CB1, abundantly expressed in the brain and at many peripheral sites
  • CB2, expressed in the immune system and also present in some neuron subpopulations and glioma cells
  • ...3 more annotations...
  • antitumoral agents
  • Aside from THC, C. sativa produces approximately 70 other cannabinoids, although, unlike THC, many of them exhibit little affinity for CB receptors (10, 20). Of interest, at least one of these components, namely, cannabinol (CBD; Supplementary Fig. 1), has been shown to reduce the growth of different types of tumor xenografts including gliomas
  • the combined administration of THC and CBD is being therapeutically explored (10, 20, 26), although its effects on the proliferation and survival of cancer cells have only been analyzed in vitro
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    THC found to augment chemotherapy in the glioblastoma cell culture study.
Nathan Goodyear

Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. - PubMed - NCBI - 0 views

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    THC induces apoptosis of glioblastoma cells via CB1 receptor signaling.
Nathan Goodyear

The role of cannabinoids in prostate cancer: Basic science perspective and potential cl... - 0 views

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    THC and prostate cancer
Nathan Goodyear

In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines - 0 views

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    High CBD downregulates prostate CBD1, CBD2, chemosensitizes CSCs, suppressed cancer cell formation, down regulated IL-6 and IL-8, decreased PSA, and VEGF.
Nathan Goodyear

Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system - 0 views

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    Great read on the use of CBD, THC in nausea/vomiting. Data in humans is lacking and most of the data is related to prescription drugs.
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