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Nathan Goodyear

Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression - 0 views

www.ncbi.nlm.nih.gov/...PMC2736626

Quercetin cancer

shared by Nathan Goodyear on 27 Nov 18 - No Cached
  • Nathan Goodyear on 27 Nov 18
     
    Quercetin inhibits S1 to M phase in the cell cell growth cycle in in vivo study. The problem with Quercetin is the high therapeutic window, 25 micoM to 200 microM, that is unobtainable by oral intake.
indiacardiacsurg

Patients with High Level of Creatinine Can Undergo Angiography in India - 101 Press Rel... - 0 views

www.101pressrelease.com/n-undergo-angiography-in-india

India's best angioplasty surgeons Angiography in India angioplasty surgeons India angioplasty price

shared by indiacardiacsurg on 25 Nov 21 - No Cached
  • indiacardiacsurg on 25 Nov 21
     
    India's best angioplasty surgeons have accelerated the window for endovascular stroke therapy from 6 to 24 hours, providing the choice of treating more ischemic stroke patients. For Consultation International Helpline Number : +91-9370586696 Email id: enquiry@indiacardiacsurgerysite.com
Nathan Goodyear

Review of health risks of low testosterone and testosterone administration - 0 views

www.ncbi.nlm.nih.gov/...PMC4391003

low Testosterone low T Testosterone men male hormone hormones health

shared by Nathan Goodyear on 28 Apr 15 - No Cached
  • Hypogonadism may be defined either as serum concentration of T (either total T, bioavailable T or free T) or as low T plus symptoms of hypogonadism
  • The Baltimore Longitudinal Study on Aging reported the incidence of total serum T < 325 ng/dL to be 20% for men in their 60s, 30% for men in their 70s and 50% for men over 80
  • The Massachusetts Aging Male Study reported that 12.3% of men aged 40 to 70 had a total serum T of < 200 ng/dL with 3 or more symptoms of hypogonadism
  • ...19 more annotations...
  • The Boston Area Community Health Study reported that 5.6% of men aged 30 to 70 were hypogonadal, as defined by total serum T < 300 ng/dL; or, free serum T < 5 ng/dL plus 3 or more symptoms of hypogonadism
  • In a health screening project among 819 men in Taiwan, the prevalence of hypogonadism (total serum T < 300 ng/dL) ranged from 16.5% for men in their 40s, 23.0% for men in their 50s, 28.9% for men in their 60s, and 37.2% for men older than 70 years of age
  • The prevalence of hypogonadism among men in Taiwan is higher than the prevalence reported in the Massachusetts Male Aging Study
  • CAG repeat sequence, within the androgen receptor (AR). Rajender et al[12] reviewed over 30 studies on the AR trinucleotide repeat and infertility
  • suggestion that CAG repeat length may determine androgen responsiveness, this issue is not clearly settled
  • reported prevalence of low T in older men range from 5.6% to 50%
  • Those in the hypogonadal group (n = 4269) had direct health care costs, that exceeded the eugonadal group (n = 4269) by an average of $7100 over the course of the observation window
  • higher economic burden and presence of co-morbidities for hypogonadism
  • minor to moderate improvements in lean mass and muscle strength
  • increased bone mineral density
  • modest enhancement in sexual function
  • reduced adiposity
  • lessening of depressive symptoms
  • Meta-analyses of clinical TRT trials as of 2010 have identified three major adverse events resulting from TRT: (1) polycythemia; (2) an increase in prostate-related events; and (3) and a slight reduction in serum high-density lipoprotein (HDL) cholesterol
  • polycythemia (> 3.5-fold increase in risk
  • TRT produced a 40% prostate enlargement in older hypogonadal male Veterans over 12 mo
  • no published analysis has reported measurable increases in prostate cancer risk or Gleason score in men undergoing TRT, or in hypogonadal men with a history of prostate cancer undergoing TRT
  • the prostate which highly expresses the type II 5α-reductase enzyme. Inhibition of this enzyme via finasteride (a type II 5α-reductase inhibitor) or dutasteride (a dual type I and II 5α-reductase inhibitor) reduces circulating DHT 50%-75% and > 90%, respectively[47], and reduces prostate mass[48] and prostate cancer risk
  • Normally estradiol partially regulates testosterone levels, at the hypothalamus, blunting LH and FSH release from the pituitary. As a selective estrogen receptor modulator, CC interrupts this pathway, and consequently there is a greater stimulation for the production of testosterone in Leydig cells
    • Nathan Goodyear
      Nathan Goodyear on 28 Apr 15
       
      this would only apply if E1 and/or E2 levels were elevated, which the authors make no mention of.
  • Nathan Goodyear on 28 Apr 15
     
    to be read
Nathan Goodyear

Omega Research - 0 views

www.omega-research.com/researchview.php

Omega-3 vitamin C E antioxidants oxidative stress infertility

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • These data have important implications for the supplementation of a combination of omega-3 fatty acids and antioxidants in the successful management of female infertility.
  • Nathan Goodyear on 15 Dec 10
     
    omega 3 and antioxidants aid in infertility
Nathan Goodyear

Saliva--a diagnostic window to the body, both in h... [J Med Life. 2009 Apr-Jun] - PubM... - 0 views

www.ncbi.nlm.nih.gov/...20108531

saliva testing salivary diagnostic

shared by Nathan Goodyear on 19 Jan 11 - No Cached
  • Saliva includes a large number of inorganic and organic compounds, which act as a "mirror of the body's health."
  • Nathan Goodyear on 19 Jan 11
     
    saliva testing is broad in its diagnostic potential
Nathan Goodyear

Fermented wheat germ extract inhibits glycolysis/p... [J Biol Chem. 2002] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...12351627

fermented wheat germ Avemar cancer therapy treatment

shared by Nathan Goodyear on 09 Feb 11 - No Cached
  • Avemar exhibits about a 50-fold higher IC(50) (10.02 mg/ml) for peripheral blood lymphocytes to induce a biological response, which provides the broad therapeutic window for this supplemental cancer treatment modality with no toxic effects.
  • Nathan Goodyear on 09 Feb 11
     
    Fermented wheat germ extract (Avemar) shows benefit in cancer treatment with no toxic side effects
Nathan Goodyear

Toxic environment and obesity pandemia: is there a... [Ital J Pediatr. 2010] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...20205780

environment toxic obesity

shared by Nathan Goodyear on 06 Apr 11 - No Cached
  • Recent cumulating evidence suggests that obesity may represent an adverse health consequence of exposure during the critical developmental windows to environmental chemicals disrupting endocrine function. Moreover, exposure to these chemicals seems to play a key role in the development of obesity-related metabolic and cardiovascular diseases.
  • Nathan Goodyear on 06 Apr 11
     
    Toxic environment and obesity
Nathan Goodyear

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting M... - 0 views

www.cell.com/...S0092-8674(14)00821-6

antibiotics obesity gut flora microbiome bacteria metabolism

shared by Nathan Goodyear on 20 Aug 14 - No Cached
  • Nathan Goodyear on 20 Aug 14
     
    Study finds antibiotics given in late-pregnancy and during first months of life led to obesity in mice via altered gut flora.  This timed exposure was equal to life-time exposure.  This study points to the timing of antibiotic exposure as the key.
Nathan Goodyear

JISSN | Full text | Nutrient timing revisited: is there a post-exercise anabolic window? - 0 views

www.jissn.com/5

exercise recovery training protein

shared by Nathan Goodyear on 18 Nov 14 - No Cached
  • Nathan Goodyear on 18 Nov 14
     
    review study finds protein at 0.4 to 0.5 g/kg of LBM pre and post work out maximizes the anabolic effect.
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