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Nathan Goodyear

New test suggests antidepressant Paxil may promote breast cancer - latimes.com - 0 views

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    article on upcoming publication of study showing Paxil has estrogenic effect. Likely through receptors from paxil itself or metabolites.
Nathan Goodyear

Selective serotonin reuptake inhibitors - PubMed Mobile - 0 views

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    SSRI's have variable inhibition of CYP.  Fluvoxamine was found to be the most potent inhibitor.  CYP3A4 and CYP2D6 were found to be the main targets of inhibition.  
Nathan Goodyear

Elevated Serum Thyrotropin in Thyroxine-Treated Patients with Hypothyroidism Given Sert... - 0 views

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    zoloft lowers thyroid function
Nathan Goodyear

Serotonin transporter occupancy of five selective ... [Am J Psychiatry. 2004] - PubMed ... - 0 views

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    SSRI's and serotonin transporter effect
Nathan Goodyear

Receptor alterations associated with serotonergic ... [J Clin Psychiatry. 1987] - PubMe... - 0 views

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    SSRI's result in down-regulation of serotonin responsiveness through down-regulation of serotonin receptors
Nathan Goodyear

PLoS ONE: Antidepressants and Breast and Ovarian Cancer Risk: A Review of the Literatur... - 0 views

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    Antidepressants shown to increase Breast and Ovarian Cancer risk in review of 61 articles. Clear relationship found, but exact risk still needs further research.  Interestingly, the pharmaceutical industry's research, showed no risk.
Nathan Goodyear

Efficacy and Safety of Curcumin in Major Depre... [Phytother Res. 2013] - PubMed - NCBI - 0 views

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    curcumin found to be statistically similar to fluoxetine in depression;  In combination there is an adjuvant effect to increase the efficacy.
Nathan Goodyear

The clinical effectiveness of sertraline in primary care and the role of depression sev... - 0 views

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    SSRI's don't work; but not new information.
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