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Nathan Goodyear

Mechanisms Linking Inflammation to Insulin Resistance - 0 views

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    Inflammation, through a variety of signaling mechanisms, directly causes insulin resistance.
Nathan Goodyear

Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells thro... - 0 views

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    Lipopolysaccharide (LPS) activates Toll-like 4 receptors (TLR-4) to increase cancer invasion, growth, and metastasis.
Nathan Goodyear

Curcumin Blocks the Activation of Androgen and Interlukin‐6 on Prostate‐Speci... - 0 views

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    IL‐6 increases PSA and androgen receptor expression through a STAT3‐dependent pathway in the absence of androgen in LNCaP cells. Our results agreed with those of an earlier study that indicated that IL‐6 induced expression of the androgen receptor, which up‐regulated PSA promoter activity in the androgen‐independent pathway. Moreover, curcumin blocked stimulation of IL‐6 on the androgen receptor, which attenuated PSA gene expression in a ligand‐independent manner.
Nathan Goodyear

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhib... - 0 views

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    Melatonin again shown to have broad anti-cancer properties.
Nathan Goodyear

Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review) - 0 views

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    Zinc reduces inflammatory response consistent with cytokine storm. In addition, it has anti-viral and anti-bacterial activity. It has also been shown to increase NK cell activity.
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