Group items tagged

This is a dissertation, but they found ER alpha expression in all meningioma samplings. This is in contrast to previous studies. As further research has come with meningiomas, more ER presence is found, likely due to improved testing techniques. What is interesting here is that Low/no PR status was associated with Increased ER alpha status. This has been shown to be a more pro-inflammatory/pro-growth picture in disease states, such as breast and prostate CA.

ER alpha and ER beta found to be expressed in meningiomas.  ER alpha was expressed more by the meningiomas.

Hormones linked to increase meningioma in women.   Clearly, the evidence shows that hormone receptors play a significant role in the growth and the potential management of these tumors.

This study finds an immunologic component to meningioma in men.

this study suggests that Pb exposure, in those with ALAD polymorphism, have an increased risk of meningioma.

Both endogenous and exogenous hormone exposure in women is associated with increased risk for meningioma.

dental x-rays found to increase risk of meningioma.

Granted, this is an Australian study, but they found an increasing incidence of certain tumors: significant increase in glioblastoma multiforme in both men and women and increasing trends of meningioma's in men.  The good news, is they found a decreasing incidence of Schwannoma in women.

Good review on the current evidence of Meningioma's.  Good statistical discussion on the risk factors, associations, and pathophysiology of meniingioma's.

Good study shows that genetic polymorphisms play role in brain tumor risk with oxidative damage.  This study found an increased risk with SOD 2/3, and with CAT polymorphisms.  

another study that showed that lead exposure in susceptible individuals increased risk of CNS tumors, including menngiomas, and gliomas.  The apparent mechanism in this study was proposed through oxidative damage.  

This study found that the presence of progesterone receptors was a favorable marker for those with meningioma's.  Only, a small number of estrogen receptors were found.  This study was from 1997.