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Nathan Goodyear

Neuroprotective Sirtuin ratio reversed by ApoE4 - 0 views

www.pnas.org/...1314145110.abstract

ApoE4 alzheimer's disease Alzheimer's disease sirtuins SIRT1 resveratrol

shared by Nathan Goodyear on 23 Oct 13 - No Cached
  • Nathan Goodyear on 23 Oct 13
     
    ApoE4 allele is known to increase Alzheimer's disease by 10 fold.  One mechanism is through a lowering of SirT1 and an increase in the SirT1:SirT2 ratio.  This SirT1 is the target of resveratrol in red wine.
Nathan Goodyear

Better memory functioning associated with higher total and LDL cholesterol levels in ve... - 0 views

www.ncbi.nlm.nih.gov/...PMC2614555

cholesterol LDL brain neurology memory levels elderly

shared by Nathan Goodyear on 19 Jun 12 - No Cached
  • Nathan Goodyear on 19 Jun 12
     
    higher total cholesterol and LDL associated with better memory in the elderly population.  This was present in those without APOE4 allele
Nathan Goodyear

Apolipoprotein E and Alzheimer disease: risk, mechanisms, and therapy - 0 views

www.ncbi.nlm.nih.gov/...PMC3726719

ApoE ApoE4 alzheimer Alzheimer's disease brain health

shared by Nathan Goodyear on 08 Dec 17 - No Cached
  • Nathan Goodyear on 08 Dec 17
     
    Great review on APOE and its contribution to Alzheimer's disease risk.
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