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"We found that adult Nod2-deficient mice display a substantially altered microbial community structure and a significantly elevated bacterial load in their faeces and terminal ileum compared to their wild-type counterparts. Interestingly, we demonstrate that these findings are also present in weaning mice, indicating a profound influence of Nod2 on the early development and composition of the intestinal microbiota. We demonstrate that NOD2 genotypes also influence the microbial composition in humans. Conclusions Our results point to an essential role of Nod2 for the temporal development and composition of the host microbiota, both in mice and in humans, which may contribute to the complex role of NOD2 for the aetiopathogenesis of Crohn's disease. "

The Internet has become not only a tool for disseminating knowledge through scientific publications, but it also has the potential to shape scientific research through expanding the field of metaknowledge - the study of knowledge itself, according to an article published by University of Chicago researchers in the journal Science.

Web of Science ® provides researchers, administrators, faculty, and students with quick, powerful access to the world's leading citation databases.  Authoritative, multidisciplinary content covers over 12,000 of the highest impact journals worldwide, including Open Access journals and over 150,000 conference proceedings.  You'll find current and retrospective coverage in the sciences, social sciences, arts, and humanities, with coverage to 1900. Overcome information overload and focus on essential data across more than 250 disciplines.

"uBiome is a citizen science project that allows the public access to cutting edge sequencing technology to understand their health through the microbiome. How does the microbiome affect my health? We are all covered in trillions of microbes -- in fact, they outnumber human cells 10:1. The trillions of bacteria live on and in us are collectively called the microbiome. Like the rainforest, the healthy human microbiome is a balanced ecosystem. The correct balance of microbes keeps potential pathogens in check and regulates our immune system. Microbes also perform essential functions such as digesting food and synthesizing vitamins. Studies have also linked the microbiome to human mood and behavior, as well as many gut disorders, eczema, and chronic sinusitis."

"Die Ergebnisse zeigen, dass das angeborene Fluchtverhalten auf Kohlendioxid in Fruchtfliegen je nach ihrem Sättigungszustand von zwei parallelen neuronalen Schaltkreisen gesteuert wird. „Ist die Fliege hungrig, verlässt sie sich nicht mehr auf die "direkte Leitung", sondern benutzt Hirnzentren, mit denen sie interne und äußere Signale abwägen und eine ausgewogene Entscheidung treffen kann", erklärt Grunwald-Kadow und fügt hinzu: „Es ist faszinierend, in welchem Ausmaß der Stoffwechsel und Hunger die verarbeitenden Prozesse im Gehirn beeinflussen." ***** Lasse B. Bräcker, K.P. Siju, Nelia Varela, Yoshinori Aso, Mo Zhang, Irina Hein, Maria Luisa Vasconcelos, Ilona C. Grunwald Kadow Essential role of the mushroom body in context dependent CO2 avoidance in Drosophila Current Biology, 13 June 2013 Max-Planck-Institut für Neurobiologie"

"Rather, these successful men needed to also be blessed with "zeal and with capacity for hard labour." This study is a first glimpse into those essential qualities described by Galton, helping us map out the individual differences that make it slightly easier for some people to engage in hard labor. These diligent souls seem to get a bit more pleasure from the possibility of reward, but they also seem less sensitive to their inner complainer, that disruptive voice reminding them that minesweeper is more fun than editing, or that the ballgame on television is much more entertaining than their homework. At any given moment, there is a tug of war unfolding in our head, determining whether or not we're willing to put in the effort. This sentence only exists because, for a few minutes at least, I was able to win the war."

This project, the Semantically-Enabled Science Data Integration (SESDI), will demonstrate how ontologies implemented within existing distributed technology frameworks will provide essential, re-useable, and robust, support for an evolution to science measurement processing systems (or frameworks) as well as for data and information systems (or framework) support for NASA Science Focus Areas and Applications.

Ai Research is a leading artificial intelligence research project. At Ai, we're creating a new form of life. Our expanding web site is an essential part of the emerging global discussion about artificial intelligence. On this website, we showcase the state of the art in pattern-matching conversational machines, demonstrated by Alan, and in reinforcement learning algorithms, demonstrated by HAL. Use our forums, original papers, online labs, demos and links to explore what's happening both at Ai (the project) and in AI (the field).

When a tube is damaged, it needs to be repaired to restore its function for better efficiency of the boiler. In that case

"The Turing test is a test of a machine's ability to exhibit intelligent behavior equivalent to, or indistinguishable from, that of a human. The test is an essential concept in the philosophy of artificial intelligence. Wikipedia"

The livestock and dairy farming industry forms one of the largest employers in the industrial sector. For entrepreneurs, it also offers a lucrative opportunity to reap profits with minimal physical labor.

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Swiss researchers have reportedly managed to make germanium suitable for lasers, which is important to eventually enable microprocessor components to communicate using light that is 10 times faster than electric currents, essentially becoming much faster photonic computers.

Throughout our history, mankind has created tools the same way, essentially using the top-down approach. Think about it. In the stone age, a sharp cutting tool was fashioned by using a larger stone to chip away pieces until the cutting stone was sharp enough. Today, a computer chip is made by a large laser that etches the circuits into a piece of silicon.

You can protect trees from the damage done by rodents and animals with fences. To protect trees from such rodents and pests, it is essential to install a fence (offered by Coastline Sediment Control) around every tree planted alongside roads and pathways.

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An essential element of laboratory experimentation and research, chemistry lab equipment supplier and manufacturers create durable yet precise tools that meet the requirements of various scientific disciplines.

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