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A new new brain imaging system that can identify a subject's simple thoughts may lead to clearer diagnoses for Alzheimer's disease or schizophrenia - as well as possibly paving the way for reading people's minds. Michael Greicius at Stanford University in California and colleagues used functional magnetic resonance imaging (fMRI) to identify patterns of brain activity associated with different mental states. He asked 14 volunteers to do one of four tasks: sing songs silently to themselves; recall the events of the day; count backwards in threes; or simply relax. Participants were given a 10-minute period during which they had to do this. For the rest of that time they were free to think about whatever they liked. The participants' brains were scanned for the entire 10 minutes, and the patterns of connectivity associated with each task were teased out by computer algorithms that compared scans from several volunteers doing the same task. This differs from previous experiments, in which the subjects were required to perform mental activities at specific times and the scans were then compared with brain activity when they were at rest. Greicius reasons his method encourages "natural" brain activity more like that which occurs in normal thought.

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"Everybody likes a simple cause and effect - something we can point to and say (ommitting a few choice words to the perpetrators), 'Fix this and the bees will be right again.' Reality is rarely so straightforward. As the bee decline has progressed I've lost count of the simple 'causes' that have been presented. Among the more memorable are: * mobile 'phones (the absolute 'definite cause' of choice a couple of years ago) * mobile base stations, power lines and other strong electromagnetic sources (a perennial favourite for any malaise) * alien abduction (hopefully they have smaller probes for abducted bees...) * God's punishment (pro gay-marriage states in the USA have more cases of CCD) Leo's article shows neonicotinoids are at least a plausible candidate and they are surely not good for bees, but the argument for these being the explicit 'cause' of global bee decline is still not particularly strong. The risk here is that the media and vocal lobbyists are going off on a righteous crusade to the detriment of more diligent, and maybe less newsworthy, efforts to get to the root of a complex problem. Rather than reviewing the evidence here, I recommend a visit to Randy Oliver's website where his two recent articles from the American Bee Journalon this topic can be found, along with some further commentary on his home page. Interested readers can also directly access the study by Henry et. al. (2012a), the commentry on this study by Creswell and Thompson (2012), the response to the comment (Henry et. al. 2012b) and to the meta-analysis of toxicological studies on imidacloprid by Creswell (2010). An example of one such study is Cutler and Scott-Dupree (2007). Links to all are included below. These are original material rather than reportage and demonstrate the complexity of the issue. As food for thought, I'll leave you with the following: * Neonicotinoids are widely used in Australia and our bees are not (yet) in decline."

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""You'll see I wear only gray or blue suits," he said. "I'm trying to pare down decisions. I don't want to make decisions about what I'm eating or wearing. Because I have too many other decisions to make." He mentioned research that shows the simple act of making decisions degrades one's ability to make further decisions. It's why shopping is so exhausting. "You need to focus your decision-making energy. You need to routinize yourself. You can't be going through the day distracted by trivia." The self-discipline he believes is required to do the job well comes at a high price. "You can't wander around," he said. "It's much harder to be surprised. You don't have those moments of serendipity."

This book contains excellent written text for the students of B.Pharm. 1st Year. It covers whole syllabus prescribed by the AICTE all over the India, and new syllabus prescribed by the GBTU (Lucknow) and MMTU (Noida). This is the first book which is written according to it. It contains all the important questions of each chapter, along with important objective questions, which helps students to revise their knowledge in the subject. This book contains a complete and comprehensive material on various topics of pharmaceutical chemistry. The topics have been explained in such a simple way that students need not study any other book for this subject. Various tables are provided for important topics, apart from that flow charts are used in simple language, which looks like simplified notes.

The Intelligence in Wikipedia Project aims to accelerate the extraction of Wikipedia knowledge, e.g. with construction of infoboxes, and link the resulting schemata together to form a knowledge base of outstanding size. Not only will this `semantified Wikipedia' be an even more valuable resource for AI, but it will support Faceted browsing and simple forms of inference that may increase the recall of question-answering systems.

"How many mammal species live in the forest? It sounds like a simple question, but the actual distributions of shy, small or rare mammals are often murky, confounding conservationists seeking to protect them. Yet a paper published online on Tuesday in the journal Molecular Ecology explores a new way to track biodiversity: by capturing flies that feed on carcasses. The flies' stomachs offer DNA diaries of their recent meals, giving scientists clues to which animals live and die in the forest. "The animals are there, but you just don't see them," said Fabian Leendertz, a wildlife epidemiologist at the Robert Koch Institute in Berlin and an author of the paper. "Those flies will find them and will tell us what is there"

"People swap bacteria all the time-through sneezes and coughs, through hugs and sex, or through touching the same surfaces. Then there are people who swap bacteria because a doctor deliberately transplants faeces from one into the other. This isn't a bizarre medical perversion. It's usually a life-saving gambit. Faecal transplants-which are exactly what they sound like-are used to treat people who suffer from intense diarrhoea following rounds of antibiotics. The goal is simple: recalibrate the beneficial bacteria in a person's gut to fight off the ones that are causing them harm."

AskMe - Experiment Publisher is a simple to use software package for users to publish their large scale life science experiment data on to the web by use of data mining and visualization concepts. With use of AskMe, scientists can share these datasets easily with their collaborators or they can be made publicly accessible to the scientific community by Sciencenet - our distributed peer to peer search and share engine.

"We were determined to build one singular AI. This means Remi is capable of handling complex requests easily. Things like 'Can you get me a taxi to my meeting with John Smith and find me a good coffee on the way' are simple for Remi."

""We wondered how individuals assess the credibility of other people in simple social interactions," said Read Montague, director of the Human Neuroimaging Laboratory and the Computational Psychiatry Unit at the Virginia Tech Carilion Research Institute, who led the study. "We found a strong correlation between the amygdala and a baseline level of distrust, which may be based on a person's beliefs about the trustworthiness of other people in general, his or her emotional state, and the situation at hand"

"vgl. Susan Cain! Von schüchternen Verlierern und vorwitzigen Gewinnern.. Während die eine ihre Tentakel noch eingezogen hat, macht sich die andere schon längst wieder zum Angriff bereit und sticht zu: Wer glaubt, Seeanemonen seien simple Wassertiere, die nur von der Strömung bewegt werden, irrt. Biologen konnten nun das komplexe Kampfverhalten der Blumentiere dokumentieren. Wer in einem Seeanemonen-Kampf der glückliche Sieger ist, hängt wesentlich vom Charakter der Blumentiere ab, sagen Fabian Rudin und Mark Briffa von der University of Plymouth."

"However, anthropological datasets show enormous complexity in how and why men and women behave the ways that they do [vi]. Studies in human biology and anthropology regularly demonstrate a dynamic flexibility and complex biocultural context for all human behavior, and this is especially true for gender.... No matter how much some want it to be true, it is just not that simple; there are no clear cut and easy answers to why we do what we do, and why men and women sometimes have problems getting along. To ignore the enormous wealth of data on how men and women are similar AND different and to try to tackle this enormously complex reality via one-dimensional approaches is just poor science."

"I am going to try and experiment within an experiment today. I cloned a couple genes from yeast and have been spending months now trying to get them into several vectors for my combinatorial overexpression project. However, as it goes with wet messy biology, this seemingly simple process has been fighting me tooth and nail. I have retrieved one good clone out of 56 minipreps (plasmid construct isolation) and tried several ligations. So I have tripled down this week. In the picture here, I have 32 tubes, each with 5 individual E. coli colonies. That is a grand total of 160 isolates. 1.5 mL of cells have been transferred from overnight cultures and I am about to spin, lyse, and retrieve."

AskMe - Experiment Publisher is a simple to use software package for users to publish their large scale life science experiment data on to the web by use of data mining and visualization concepts. With use of AskMe, scientists can share these datasets easily with their collaborators or they can be made publicly accessible to the scientific community by Sciencenet - our distributed peer to peer search and share engine.

"MIT-based researchers and instructors Marcelo Coelho and Skylar Tibbits teamed up to tackle this very problem. Working under a grant from Ars Electronica, the pair conceived of a whole new way to do 3-D printing. Hyperform is a new strategy for designing and printing large objects irrespective of a printer's bed size. So not only can you print out that chair at home, you can also print a table, bed frame, and everything else you need to furnish a bedroom. The solution is breathtakingly simple. By merely folding the object you want to print, you can jig it to fit into a small-scale printer. In Tibbits and Coelho's project, the object is rendered in 1-D--a line--and endlessly folded into a space-filling curve proportioned to the printer's cubic dimensions. (The designers partnered with Formlabs and iterated the process using a Form 1 tabletop printer.) When the object is exhumed from the printer bed, it doesn't at all resemble its final shape. Rather, it's a dense cluster of thin but sturdy polymer links packaged in a three-dimensional puzzle that can be intuitively assembled"

"api.ai equips developers with a simple way to make their products listen, understand, and talk to users. The api.ai platform combines natural language understanding with speech recognition and synthesis, enabling speech interfaces to be easily added to any solution."