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Skeptical Debunker

Use of DNA evidence is not an open and shut case, professor says - 0 views

  • In his new book, "The Double Helix and the Law of Evidence" (Harvard University Press), Kaye focuses on the intersection of science and law, and emphasizes that DNA evidence is merely information. "There's a popular perception that with DNA, you get results," Kaye said. "You're either guilty or innocent, and the DNA speaks the truth. That goes too far. DNA is a tool. Perhaps in many cases it's open and shut, in other cases it's not. There's ambiguity."
  • One of the book's key themes is that using science in court is hard to do right. "It requires lawyers and judges to understand a lot about the science," Kaye noted. "They don't have to be scientists or technicians, but they do have to know enough to understand what's going on and whether the statements that experts are making are well-founded. The lawyers need to be able to translate that information into a form that a judge or a jury can understand." Kaye also believes that lawyers need to better understand statistics and probability, an area that has traditionally been neglected in law school curricula. His book attempts to close this gap in understanding with several sections on genetic science and probability. The book also contends that scientists, too, have contributed to the false sense of certainty, when they are so often led by either side of one particular case to take an extreme position. Scientists need to approach their role as experts less as partisans and more as defenders of truth. Aiming to be a definitive history of the use of DNA evidence, "The Double Helix and the Law of Evidence" chronicles precedent-setting criminal trials, battles among factions of the scientific community and a multitude of issues with the use of probability and statistics related to DNA. From the Simpson trial to the search for the last Russian Tsar, Kaye tells the story of how DNA science has impacted society. He delves into the history of the application of DNA science and probability within the legal system and depicts its advances and setbacks.
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    Whether used to clinch a guilty verdict or predict the end of a "CSI" episode, DNA evidence has given millions of people a sense of certainty -- but the outcomes of using DNA evidence have often been far from certain, according to David Kaye, Distinguished Professor of Law at Penn State.
Erich Feldmeier

Science - Quora - 0 views

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    "Science is a scheme for thinking and solving issues using evidence. It requires hypotheses, i.e. potential truths that require examination. A hypothesis or scientific idea is only as strong as the evidence to support it. Strong evidence is predictive and reproducible, weak evidence is less so. Scientific thinking gives greater weight to the stronger evidence base."
Skeptical Debunker

What causes autism? Exploring the environmental contribution : Current Opinion in Pedia... - 0 views

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    Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.
Erich Feldmeier

Gomez-Pinilla: Diabetes 'Metabolic syndrome' in the brain: deficiency in omega-3 fatty ... - 0 views

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    "We provide novel evidence for the effects of metabolic dysfunctions on brain function using the rat model of metabolic syndrome induced by high fructose intake. * We describe that the deleterious consequences of unhealthy dietary habits can be partially counteracted by dietary supplementation of n-3 fatty acid. * High sugar consumption impaired cognitive abilities and disrupted insulin signalling by engaging molecules associated with energy metabolism and synaptic plasticity; in turn, the presence of docosahexaenoic acid, an n-3 fatty acid, restored metabolic homeostasis. * These findings expand the concept of metabolic syndrome affecting the brain and provide the mechanistic evidence of how dietary habits can interact to regulate brain functions, which can further alter lifelong susceptibility to the metabolic disorders. "
Erich Feldmeier

Belly Bacteria Boss The Brain - Science News - 0 views

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    "But, "one has to be cautious. This is exciting science in rodents, but you can't just extrapolate to humans," says Emeran Mayer, a gastroenterologist and neuroscientist at UCLA's Center for Neurobiology of Stress who was not involved in the new study. Drug and food companies that make probiotics - beneficial bacteria taken in a pill or eaten in food such as yogurt - hope the products can help relieve depression, improve weight loss and cure other conditions, but there is little evidence in people that probiotics can accomplish those goals, Mayer says. "It's almost like science fiction; you can imagine the most amazing things because so little is known about it," he says. But, "So far there's really no evidence that probiotics affect emotions in humans." "
Ilmar Tehnas

Mars Express radar gives strong evidence for former Mars ocean - 1 views

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    Would be nice to see the actual strata that has been identified. As such, it is a statement with no supporting evidence. Has a paper been written?
Erich Feldmeier

Cadotte, Dinnage, Tilman: ESA Online Journals - Phylogenetic diversity promotes ecosyst... - 0 views

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    "Our results indicate that communities where species are evenly and distantly related to one another are more stable compared to communities where phylogenetic relationships are more clumped. This result could be explained by a phylogenetic sampling effect, where some lineages show greater stability in productivity compared to other lineages, and greater evolutionary distances reduce the chance of sampling only unstable groups. However, we failed to find evidence for similar stabilities among closely related species. Alternatively, we found evidence that plot biomass variance declined with increasing phylogenetic distances, and greater evolutionary distances may represent species that are ecologically different (phylogenetic complementarity). Accounting for evolutionary relationships can reveal how diversity in form and function may affect stability."
Walid Damouny

Stanford's Hank Greely puts neuroscience on trial - 0 views

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    "A lawyer is trying to convince a jury that his client really is crazy. It's usually a tough argument to sell in a court of law. But what if the lawyer has a picture of his client's brain that shows there's something biologically wrong with it? Can that evidence help persuade a jury? Should it even be allowed as evidence?"
thinkahol *

Evidence lacking for widespread use of costly antipsychotic drugs, study suggests - 0 views

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    ScienceDaily (Jan. 7, 2011) - Many prescriptions for the top-selling class of drugs, known as atypical antipsychotic medications, lack strong evidence that the drugs will actually help, a study by researchers at the Stanford University School of Medicine and University of Chicago has found. Yet, drugs in this class may cause such serious effects as weight gain, diabetes and heart disease, and cost Americans billions of dollars.
thinkahol *

How To Shut Up Pesky Creationists - YouTube - 1 views

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    Easy to understand evidence for a common ape-like human/chimp ancestor. One of thousands of collaborating pieces of evidence, but this one is very conceptual. Whip it out anytime a creationist starts preaching.
Skeptical Debunker

Scientists reveal driving force behind evolution - 0 views

  • The team observed viruses as they evolved over hundreds of generations to infect bacteria. They found that when the bacteria could evolve defences, the viruses evolved at a quicker rate and generated greater diversity, compared to situations where the bacteria were unable to adapt to the viral infection. The study shows, for the first time, that the American evolutionary biologist Leigh Van Valen was correct in his 'Red Queen Hypothesis'. The theory, first put forward in the 1970s, was named after a passage in Lewis Carroll's Through the Looking Glass in which the Red Queen tells Alice, 'It takes all the running you can do to keep in the same place'. This suggested that species were in a constant race for survival and have to continue to evolve new ways of defending themselves throughout time. Dr Steve Paterson, from the University's School of Biosciences, explains: "Historically, it was assumed that most evolution was driven by a need to adapt to the environment or habitat. The Red Queen Hypothesis challenged this by pointing out that actually most natural selection will arise from co-evolutionary interactions with other species, not from interactions with the environment. "This suggested that evolutionary change was created by 'tit-for-tat' adaptations by species in constant combat. This theory is widely accepted in the science community, but this is the first time we have been able to show evidence of it in an experiment with living things." Dr Michael Brockhurst said: "We used fast-evolving viruses so that we could observe hundreds of generations of evolution. We found that for every viral strategy of attack, the bacteria would adapt to defend itself, which triggered an endless cycle of co-evolutionary change. We compared this with evolution against a fixed target, by disabling the bacteria's ability to adapt to the virus. "These experiments showed us that co-evolutionary interactions between species result in more genetically diverse populations, compared to instances where the host was not able to adapt to the parasite. The virus was also able to evolve twice as quickly when the bacteria were allowed to evolve alongside it."
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    Scientists at the University of Liverpool have provided the first experimental evidence that shows that evolution is driven most powerfully by interactions between species, rather than adaptation to the environment.
Erich Feldmeier

Maurice Levi: Winterkind Summer babies less likely to be CEOs - 0 views

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    "Levi and his co-authors, former Sauder PhD students Qianqian Du and Huasheng Gao, investigated the birth-date effect in a sample of 375 CEOs from S&P 500 companies between 1992 and 2009. "Our study adds to the growing evidence that the way our education system groups students by age impacts their lifelong success," says Prof. Levi. "We could be excluding some of the business world's best talent simply by enrolling them in school too early.""
Erich Feldmeier

Older prostate cancer patients should think twice before undergoing treatment - 0 views

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    "Many men as they age will develop prostate cancer and not know it, because it's slow growing and causes no symptoms. Autopsy studies of men who died from other causes have shown that almost 30 percent over the age of 50 have histological evidence of prostate cance"
Erich Feldmeier

About us · Sense about Science - 0 views

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    "Our ethos: We help people make sense of current discussions rather than taking them back to school We stand up for scientific inquiry, free from stigma, intimidation, hysteria or censorship We want everyone, whatever their experience, to stand up for evidence in public life"
Erich Feldmeier

Elisabeth Spelke: Large number discrimination in 6-month-old infants - 0 views

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    "Abstract: Babys können rechnen / zählen Six-month-old infants discriminate between large sets of objects on the basis of numerosity when other extraneous variables are controlled, provided that the sets to be discriminated differ by a large ratio (8 vs. 16 but not 8 vs. 12). The capacities to represent approximate numerosity found in adult animals and humans evidently develop in human infants prior to language and symbolic counting."
Dave James

Successful Financial Source Of Funds Accessed In Excellent Approach - 0 views

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    No earnings evidence self employed loans are fairly trouble-free to obtain financial source in secured and unsecured form at emergency time. The borrowed amount consequential can be utilized to sort out the several requirement and demands. For trouble-free and harass free endorsement, you can like better to apply through online medium for excellent financial lending.
Janos Haits

ATLAS Experiment - 0 views

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    ATLAS is a particle physics experiment at the Large Hadron Collider at CERN. The ATLAS detector is searching for new discoveries in the head-on collisions of protons of extraordinarily high energy. ATLAS will learn about the basic forces that have shaped our Universe since the beginning of time and that will determine its fate. Among the possible unknowns are the origin of mass, extra dimensions of space, unification of fundamental forces, and evidence for dark matter candidates in the Universe.
Erich Feldmeier

D. Schreiber , M. Iacoboni: PolitPsych_Schreiber_2012.pdf (application/pdf-Objekt) - 0 views

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    While a substantial body of work has been devoted to understanding the role of negative stereotypes in racial attitudes, far less is known about how we deal with contradictions of those stereotypes. This article uses functional brain imaging with contextually rich visual stimuli to explore the neural mechanisms that are involved in cognition about social norms and race. We present evidence that racial stereotypes are more about the stereotypes than about race per se. Amygdala activity (correlated with negative racial attitudes in other studies) appeared driven by norm violation, rather than race.
Erich Feldmeier

@5eenGeno What is wrong with our bees? - Victorian Apiarists' Association (VAA) - 0 views

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    "Everybody likes a simple cause and effect - something we can point to and say (ommitting a few choice words to the perpetrators), 'Fix this and the bees will be right again.' Reality is rarely so straightforward. As the bee decline has progressed I've lost count of the simple 'causes' that have been presented. Among the more memorable are: * mobile 'phones (the absolute 'definite cause' of choice a couple of years ago) * mobile base stations, power lines and other strong electromagnetic sources (a perennial favourite for any malaise) * alien abduction (hopefully they have smaller probes for abducted bees...) * God's punishment (pro gay-marriage states in the USA have more cases of CCD) Leo's article shows neonicotinoids are at least a plausible candidate and they are surely not good for bees, but the argument for these being the explicit 'cause' of global bee decline is still not particularly strong. The risk here is that the media and vocal lobbyists are going off on a righteous crusade to the detriment of more diligent, and maybe less newsworthy, efforts to get to the root of a complex problem. Rather than reviewing the evidence here, I recommend a visit to Randy Oliver's website where his two recent articles from the American Bee Journalon this topic can be found, along with some further commentary on his home page. Interested readers can also directly access the study by Henry et. al. (2012a), the commentry on this study by Creswell and Thompson (2012), the response to the comment (Henry et. al. 2012b) and to the meta-analysis of toxicological studies on imidacloprid by Creswell (2010). An example of one such study is Cutler and Scott-Dupree (2007). Links to all are included below. These are original material rather than reportage and demonstrate the complexity of the issue. As food for thought, I'll leave you with the following: * Neonicotinoids are widely used in Australia and our bees are not (yet) in decline."
Ivan Pavlov

Cryptic new species of wild cat identified in Brazil - 0 views

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    Scientists had thought that there was a single species of housecat-sized Brazilian tigrina. However, the molecular data now show that tigrina populations in northeastern versus southern Brazil are completely separate, with no evidence of interbreeding between them. As such, they are best described as two distinct species.
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