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Janos Haits

GRANATUM - Project Vision - 0 views

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    The vision of the GRANATUM project is to bridge the information, knowledge and collaboration gap among biomedical researchers in Europe (at least) ensuring that the biomedical scientific community has homogenized, integrated access to the globally available information and data resources needed to perform complex cancer chemoprevention experiments and conduct studies on large-scale datasets.
Janos Haits

The Open Biological and Biomedical Ontologies - 0 views

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    The OBO Foundry is a collaborative experiment involving developers of science-based ontologies who are establishing a set of principles for ontology development with the goal of creating a suite of orthogonal interoperable reference ontologies in the biomedical domain. The groups developing ontologies who have expressed an interest in this goal are listed below, followed by other relevant efforts in this domain.
Janos Haits

GPUGRID - 0 views

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    GPUGRID.net is a distributed computing infrastructure devoted to biomedical research. Thanks to the contribution of volunteers, GPUGRID scientists can perform molecular simulations to understand the function of proteins in health and disease.
Erich Feldmeier

DIY Bioprinter Lets Wannabe Scientists Build Structures From Living Cells | Wired Desig... - 0 views

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    "A new bioprinter developed at a hackerspace can print living cells for less than the cost of an iPod touch. 3-D bioprinters have the potential to change the way medical research is conducted, even print living tissue and replacement organs, but they are expensive and highly specialized. They literally build living structures, like blood vessels or skin tissue, cell by cell, revolutionizing biomedical engineering. Unfortunately, they're expensive, rare, and require a Ph.D. (or two) to operate successfully. Frustrated by their cost and exclusivity, a group of makers at the DIYbio hackerspace BioCurious are developing a system open to anyone with a soldering iron and a serious passion for cell biology."
Erich Feldmeier

Sean D. Twiss und Ross Culloch Robben haben Persönlichkeit | Scienceticker - ... - 0 views

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    "Forschung: Sean D. Twiss und Ross Culloch, School of Biological and Biomedical Sciences, Durham University, und Patrick P. Pomeroy, Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews Veröffentlichung Marine Mammal Science, DOI 10.1111/j.1748-7692.2011.00523.x"
Erich Feldmeier

@biogarage @marueber Igor Efimov, Sarah Gutbrod: 3-D printer creates transformative dev... - 0 views

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    "Igor Efimov, Sarah Gutbrod Using an inexpensive 3-D printer, biomedical engineers have developed a custom-fitted, implantable device with embedded sensors that could transform treatment and prediction of cardiac disorders. The 3-D elastic membrane is made of a soft, flexible, silicon material that is precisely shaped to match the heart's outer layer of the wall. Current technology is two-dimensional and cannot cover the full surface of the epicardium or maintain reliable contact for continual use without sutures or adhesives. The team can then print tiny sensors onto the membrane that can precisely measure temperature, mechanical strain and pH, among other markers, or deliver a pulse of electricity in cases of arrhythmi"
Erich Feldmeier

Cellendes: Company - 0 views

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    "Cellendes continously expands the 3-D Life product line to provide an innovative and increasingly comprehensive technology for a broad range of applications in 3-D cell culture. Cellendes seeks collaborations with academic and industrial partners to explore and develop the use of the 3-D Life technology in complex cell-based assays and tissue models for drug screening as well as in biomedical engineering. Cellendes was founded in 2009 by Dr. Brigitte Angres and Dr. Helmut Wurst. Cellendes is a spinoff company of the NMI Natural and Medical Sciences Institute at the University of Tübingen."
thinkahol *

Artificial hippocampal system restores long-term memory, enhances cognition | KurzweilAI - 2 views

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    Theodore Berger and his team at the USC Viterbi School of Engineering's Department of Biomedical Engineering have developed a neural prosthesis for rats that is able to restore their ability to form long-term memories after they had been pharmacologically blocked. In a dramatic demonstration, Berger blocked the ability to rats to form long-term memories by using pharmacological agents to disrupt the neural circuitry that communicates between two subregions of the hippocampus, CA1 and CA3, which interact to create long-term memory, prior research has shown. The rats were unable to remember which lever to pull to gain a reward, or could only remember for 5-10 seconds, when previously they could remember for a long period of time. The researchers then developed an artificial hippocampal system that could duplicate the pattern of interaction between CA3-CA1 interactions. Long-term memory capability returned to the pharmacologically blocked rats when the team activated the electronic device programmed to duplicate the memory-encoding function. The researchers went on to show that if a prosthetic device and its associated electrodes were implanted in animals with a normal, functioning hippocampus, the device could actually strengthen the memory being generated internally in the brain and enhance the memory capability of normal rats. "These integrated experimental modeling studies show for the first time that with sufficient information about the neural coding of memories, a neural prosthesis capable of real-time identification and manipulation of the encoding process can restore and even enhance cognitive mnemonic processes," says the paper. Next steps, according to Berger and Deadwyler, will be attempts to duplicate the rat results in primates (monkeys), with the aim of eventually creating prostheses that might help human victims of Alzheimer's disease, stroke, or injury recover function. Ref.: "A Cortical Neural Prosthesis for Restoring and Enhancing
Janos Haits

The Stanford NLP (Natural Language Processing) Group - 0 views

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    "The Natural Language Processing Group at Stanford University is a team of faculty, research scientists, postdocs, programmers and students who work together on algorithms that allow computers to process and understand human languages. Our work ranges from basic research in computational linguistics to key applications in human language technology, and covers areas such as sentence understanding, machine translation, probabilistic parsing and tagging, biomedical information extraction, grammar induction, word sense disambiguation, automatic question answering, and text to 3D scene generation."
Janos Haits

Homepage | MIT EECS - 0 views

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    The Electrical Engineering and Computer Science Department is the largest department at MIT, preparing over 300 graduate and undergraduate students each year to become leaders in diverse career fields such as academia, biomedical technology, finance, consulting, law, nanotechnology and more.  MIT EECS consistently ranks top by the the U.S. News and World Reports and is known globally for its world class faculty creating the best possible education, which is based on their innovative and award winning research.
Erich Feldmeier

About - BioMed X - 0 views

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    "The BioMed X Innovation Center is an exciting new collaboration model at the interface between academia and industry. At our center, distinguished early career scientists recruited from all over the world are working jointly on novel pre-clinical research projects in the fields of biomedicine, molecular biology, cell biology, diagnostics, bioinformatics, neuroscience and nanomaterials. These interdisciplinary project teams are conducting outstanding biomedical research in an open innovation lab facility on the campus of the University of Heidelberg"
Skeptical Debunker

A mini-laboratory for all cases - Research News 03-2010-Topic 5 - Fraunhofer-Gesellschaft - 0 views

  •  »We’ll just have to wait for the results of the laboratory tests.« These words are familiar to many patients. It then usually takes several days for specimens to be sent to the laboratory and analyzed and for the doctor to receive the results. For many illnesses, however, a speedy diagnosis is crucial if the treatment is to be successful. In future, the patient might only have to sit in the waiting room for a few minutes until the results are ready. In a joint project, researchers from seven Fraunhofer institutes have developed a modular platform for in vitro diagnosis which enables various types of bioanalysis – of blood and saliva for example – to be conducted in the doctor’s surgery. »Thanks to its modular design our IVD platform is so flexible that it can be used for all possible bioanalytical tasks,« states Dr. Eva Ehrentreich-Förster from the Fraunhofer Institute for Biomedical Engineering (IBMT) in Potsdam-Golm.The core element of the mini-laboratory is a disposable cartridge made of plastic which can be fitted with various types of sensor. For an analysis the doctor fills the cartridge with reagents – binding agents which indicate the presence of certain substances such as antigens in the specimen material. Various tests or assays are available for different types of analysis. To perform an assay, the doctor only has to place the relevant substances in the cartridge and the test then takes place automatically. »We have optimized the assays so that up to 500 assay reactions can be conducted in parallel in a single analysis step,« explains Dr. Ehrentreich-Förster. Even in the case of complex analyses the doctor obtains a result within about 30 minutes. A new module on the reverse side of the cartridge also makes it possible to analyze the specimen material at DNA level.Once the cartridge has been prepared, the doctor places it in the measurement system. The results can be read out with either optical or electrochemical biosensors. The researchers have installed a readout window for both methods in the measurement system, which features a bypass through which the specimen is pumped.
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    Many illnesses can be reliably diagnosed through laboratory tests, but these in vitro analyses often use up valuable time. A system developed by Fraunhofer research scientists, which can carry out complex analyses on the spot, will soon be ready for the market.
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