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Erich Feldmeier

@biogarage #gender Macht Arbeitslosigkeit /Männer/ alt? - @bdw-redaktion - 0 views

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    "Die Forscher haben für ihre Studie die Länge der Telomere von 5.620 finnischen Frauen und Männern des Jahrgangs 1966 untersucht. Neben DNA-Proben hatten diese Personen auch Informationen über ihre Beschäftigungsverhältnisse abgegeben und ob und wie lange sie einmal arbeitslos gewesen waren. Die Auswertungen zeigten: Männer, die mindestens zwei Jahre lang arbeitslos gewesen waren, hatten doppelt so häufig signifikant verkürzte Teleomere als Männer, die durchwegs in Beschäftigung gewesen waren. Die Ergebnisse hielten auch statistischen Verfahren stand, die systematisch andere Faktoren ausschließen, die zu dem Ergebnis geführt haben könnten - beispielsweise der Gesundheitszustand, oder sozioökonomische Faktoren. Die Forscher fanden den Zusammenhang zwischen verkürzten Telomeren und Arbeitslosigkeit allerdings nicht bei den Frauen. Warum das so ist, bleibt unklar"
Janos Haits

Home | Polonsky Foundation Digitization Project - 0 views

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    "The Bodleian Libraries of the University of Oxford and the Biblioteca Apostolica Vaticana (Vatican Library) have joined efforts in a landmark digitization project with the aim of opening up their repositories of ancient texts. Over the course of the next four years, 1.5 million pages from their remarkable collections will be made freely available online to researchers and to the general public."
Erich Feldmeier

@biogarage Jamil Bhanji, Mauricio Delgado: The social brain and reward: social informat... - 0 views

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    "This research provides an understanding of the neural basis for social behavior from the perspective of how we evaluate social experiences and how our social interactions and decisions are motivated. We review research addressing the common neural systems underlying evaluation of social and nonsocial rewards. The human striatum, known to play a key role in reward processing, displays signals related to a broad spectrum of social functioning, including evaluating social rewards, making decisions influenced by social factors, learning about social others, cooperating, competing, and following social norms. WIREs Cogn Sci 2014, 5:61-73. doi: 10.1002/wcs.1266"
thinkahol *

Undersea cauldrons replicated life's ingredients - life - 27 May 2010 - New Scientist - 0 views

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    "THE precursor of life may have learned how to copy itself thanks to simple convection at the bottom of the ocean. Lab experiments reveal how DNA replication could have occurred in tiny pores around undersea vents." "To test this theory, Mast and Braun put these ingredients into tubes 1.5 millimetres long. They used a laser to heat one side of the water and create thermal convection. Sure enough, they found that the DNA doubled every 50 seconds (Physical Review Letters, vol 104, p 188102)."
Charles Daney

Dark Matter Part II: How much Normal Matter is there? : Starts With A Bang - 0 views

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    We got the same measurement no matter which method we used, finding out that 25-30% of the total energy of the Universe is in some type of matter. But, only about 0.5% of the total energy is in stars, which means that nearly all of this matter doesn't give off light! So what is the rest of this matter?
Skeptical Debunker

It's official: An asteroid wiped out the dinosaurs - Yahoo! News - 0 views

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    A giant asteroid smashing into Earth is the only plausible explanation for the extinction of the dinosaurs, a global scientific team said on Thursday, hoping to settle a row that has divided experts for decades. A panel of 41 scientists from across the world reviewed 20 years' worth of research to try to confirm the cause of the so-called Cretaceous-Tertiary (KT) extinction, which created a "hellish environment" around 65 million years ago and wiped out more than half of all species on the planet. Scientific opinion was split over whether the extinction was caused by an asteroid or by volcanic activity in the Deccan Traps in what is now India, where there were a series of super volcanic eruptions that lasted around 1.5 million years. The new study, conducted by scientists from Europe, the United States, Mexico, Canada and Japan and published in the journal Science, found that a 15-kilometre (9 miles) wide asteroid slamming into Earth at Chicxulub in what is now Mexico was the culprit. "We now have great confidence that an asteroid was the cause of the KT extinction. This triggered large-scale fires, earthquakes measuring more than 10 on the Richter scale, and continental landslides, which created tsunamis," said Joanna Morgan of Imperial College London, a co-author of the review.
Skeptical Debunker

Pliocene Hurricaines - 0 views

  • By combining a hurricane model and coupled ocean-atmosphere general circulation model to investigate the early Pliocene, Emanuel, Brierley and co-author Alexey Fedorov observed how vertical ocean mixing by hurricanes near the equator caused shallow parcels of water to heat up and later resurface in the eastern equatorial Pacific as part of the ocean wind-driven circulation. The researchers conclude from this pattern that frequent hurricanes in the central Pacific likely strengthened the warm pool in the eastern equatorial Pacific, which in turn increased hurricane frequency — an interaction described by Emanuel as a “two-way feedback process.”�The researchers believe that in addition to creating more hurricanes, the intense hurricane activity likely created a permanent El Nino like state in which very warm water in the eastern Pacific near the equator extended to higher latitudes. The El Nino weather pattern, which is caused when warm water replaces cold water in the Pacific, can impact the global climate by intermittently altering atmospheric circulation, temperature and precipitation patterns.The research suggests that Earth’s climate system may have at least two states — the one we currently live in that has relatively few tropical cyclones and relatively cold water, including in the eastern part of the Pacific, and the one during the Pliocene that featured warm sea surface temperatures, permanent El Nino conditions and high tropical cyclone activity.Although the paper does not suggest a direct link with current climate models, Fedorov said it is possible that future global warming could cause Earth to transition into a different equilibrium state that has more hurricanes and permanent El Nino conditions. “So far, there is no evidence in our simulations that this transition is going to occur at least in the next century. However, it’s still possible that the condition can occur in the future.”�Whether our future world is characterized by a mean state that is more El Nino-like remains one of the most important unanswered questions in climate dynamics, according to Matt Huber, a professor in Purdue University’s Department of Earth and Atmospheric Sciences. The Pliocene was a warmer time than now with high carbon dioxide levels. The present study found that hurricanes influenced by weakened atmospheric circulation — possibly related to high levels of carbon dioxide — contributed to very warm temperatures in the Pacific Ocean, which in turn led to more frequent and intense hurricanes. The research indicates that Earth’s climate may have multiple states based on this feedback cycle, meaning that the climate could change qualitatively in response to the effects of global warming.
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    The Pliocene epoch is the period in the geologic timescale that extends from 5 million to 3 million years before present. Although scientists know that the early Pliocene had carbon dioxide concentrations similar to those of today, it has remained a mystery what caused the high levels of greenhouse gas and how the Pliocene's warm conditions, including an extensive warm pool in the Pacific Ocean and temperatures that were roughly 4 degrees C higher than today's, were maintained. In a paper published February 25 in Nature, Kerry Emanuel and two colleagues from Yale University's Department of Geology and Geophysics suggest that a positive feedback between tropical cyclones - commonly called hurricanes and typhoons - and the circulation in the Pacific could have been the mechanism that enabled the Pliocene's warm climate.
thinkahol *

Artificial hippocampal system restores long-term memory, enhances cognition | KurzweilAI - 2 views

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    Theodore Berger and his team at the USC Viterbi School of Engineering's Department of Biomedical Engineering have developed a neural prosthesis for rats that is able to restore their ability to form long-term memories after they had been pharmacologically blocked. In a dramatic demonstration, Berger blocked the ability to rats to form long-term memories by using pharmacological agents to disrupt the neural circuitry that communicates between two subregions of the hippocampus, CA1 and CA3, which interact to create long-term memory, prior research has shown. The rats were unable to remember which lever to pull to gain a reward, or could only remember for 5-10 seconds, when previously they could remember for a long period of time. The researchers then developed an artificial hippocampal system that could duplicate the pattern of interaction between CA3-CA1 interactions. Long-term memory capability returned to the pharmacologically blocked rats when the team activated the electronic device programmed to duplicate the memory-encoding function. The researchers went on to show that if a prosthetic device and its associated electrodes were implanted in animals with a normal, functioning hippocampus, the device could actually strengthen the memory being generated internally in the brain and enhance the memory capability of normal rats. "These integrated experimental modeling studies show for the first time that with sufficient information about the neural coding of memories, a neural prosthesis capable of real-time identification and manipulation of the encoding process can restore and even enhance cognitive mnemonic processes," says the paper. Next steps, according to Berger and Deadwyler, will be attempts to duplicate the rat results in primates (monkeys), with the aim of eventually creating prostheses that might help human victims of Alzheimer's disease, stroke, or injury recover function. Ref.: "A Cortical Neural Prosthesis for Restoring and Enhancing
thinkahol *

Hubble constant: A new way to measure the expansion of the universe - 0 views

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    ScienceDaily (July 27, 2011) - Using a measurement of the clustering of the galaxies surveyed, plus other information derived from observations of the early universe, researchers have measured the Hubble constant with an uncertainly of less than 5 percent. The new work draws on data from a survey of more than 125,000 galaxies.
thinkahol *

Boys reach sexual maturity younger and younger: Phase between being physically but not ... - 0 views

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    ScienceDaily (Aug. 19, 2011) - Boys are maturing physically earlier than ever before. The age of sexual maturity has been decreasing by about 2.5 months each decade at least since the middle of the 18th century. Joshua Goldstein, director of the Max Planck Institute for Demographic Research in Rostock (MPIDR), has used mortality data to demonstrate this trend, which until now was difficult to decipher. What had already been established for girls now seems to also be true for boys: the time period during which young people are sexually mature but socially not yet considered adults is expanding.
thinkahol *

5 Things That Internet Porn Reveals About Our Brains | Sex & the Brain | DISCOVER Magazine - 1 views

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    With its expansive range and unprecedented potential for anonymity, (the Internet gives voice to our deepest urges and most uninhibited thoughts. Inspired by the wealth of unfettered expression available online, neuroscientists Ogi Ogas and Sai Gaddam, who met as Ph.D. candidates at Boston University, began plumbing a few chosen search engines (including Dogpile and AOL) to create the world's largest experiment in sexuality in 2009. Quietly tapping into a billion Web searches, they explored the private activities of more than 100 million men and women around the world. The result is the first large-scale scientific examination of human sexuality in more than half a century, since biologist Alfred Kinsey famously interviewed more than 18,000 middle-class Caucasians about their sexual behavior and published the Kinsey reports in 1948 and 1953. Building on the work of Kinsey, neuroscientists have long made the case that male and female sexuality exist on different planes. But like Kinsey himself, they have been hampered by the dubious reliability of self-reports of sexual behavior and preferences as well as by small sample sizes. That is where the Internet comes in. By accessing raw data from Web searches and employing the help of Alexa-a company that measures Web traffic and publishes a list of the million most popular sites in the world-Ogas and Gaddam shine a light on hidden desire, a quirky realm of lust, fetish, and kink that, like the far side of the moon, has barely been glimpsed. Here is a sampling of their fascinating results, selected from their book, A Billion Wicked Thoughts.
thinkahol *

New research shows that we control our forgetfulness - 1 views

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    ScienceDaily (July 5, 2011) - Have you heard the saying "You only remember what you want to remember"? Now there is evidence that it may well be correct. New research from Lund University in Sweden shows that we can train ourselves to forget things.
thinkahol *

TED Blog | The 4 ways sound affects us: Julian Treasure on TED.com - 0 views

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    Playing sound effects both pleasant and awful, Julian Treasure shows how sound affects us in four significant ways. Listen carefully for a shocking fact about noisy open-plan offices. (Recorded at TEDGlobal University, July 2009, Oxford, UK. Duration: 5:47)
Janos Haits

MIT Places Database for Scene Recognition - 0 views

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    "Scene recognition is one of the hallmark tasks of computer vision, allowing defining a context for object recognition. Here we introduce a new scene-centric database called Places, with 205 scene categories and 2.5 millions of images with a category label. Using convolutional neural network (CNN), we learn deep scene features for scene recognition tasks, and establish new state-of-the-art performances on scene-centric benchmarks. Here we provide the Places Database and the trained CNNs for academic research and education purposes."
kingwinny

enzymes used in leather industry - 0 views

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    Lipase enzymes used in leather industry has achieved good results in degreasing of crepe, fur, leather, gelatin, and the like. Candida lipolytica lipase can reduce the oil content of the raw material of the spinning material from 10% to 0.5%, to meet the spinning requirements, and does not affect the fiber strength.
David Haow

Diversity of plant parasitic nematodes associated with common beans (Phaseolus vulgaris... - 0 views

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    Common beans (Phaseolus vulgaris L.) are the most important legume staple food in Kenya coming second to maize. In Central Highlands of Kenya, the 0.4-0.5ton ha-1 output is below the genetic yield potential of 1.5-2ton ha-1 partly due pests and diseases. Plant parasitic nematodes (PPN) have been reported to cause yield losses of up to 60% on beans. Though bean production is important in the Central highlands of Kenya, information on PPN associated with the beans in the region is lacking. This study was therefore undertaken to establish the diversity of PPN associated with common beans and to assess the root knot nematode damage on beans in the region. The study covered 50 farms (32 in Kirinyaga and 18 in Embu Counties) distributed in eight localities namely Kibirigwi (L1), Makutano (L2), Kagio (L3), Mwea (L4) and Kutus (L5) in Kirinyaga County and Nembure (L6), Manyatta (L7) and Runyenjes (L8) in Embu County and covering three Agro Ecological Zones (AEZs); UM2 (L1, L2, L3 & L4), UM3 (L5, L7 & L8) and UM4 (L6) AEZs. Manyatta (L7) and Nembure (L6), had the highest and second highest gall indices, respectively, while Kibirigwi (L1), Makutano (L2) and Mwea (L4) had some of the lowest gall indices. The most common PPN in bean roots were Meloidogyne spp. Pratylenchus spp. and Scutellonema spp. with a frequency of 94.38%, 78.25% and 59.13%, respectively. This further confirm the importance of these nematodes in bean production systems. Upper Midland 3 (UM3) AEZs and UM4 had higher nematode population densities and diversity than UM2. Disease severity and nematode composition and distribution were notably low in the irrigated areas Kibirigwi, Kagio and Mwea compared to rain-fed areas such as Makutano, Nembure and Manyatta.
Dave James

5 Main Benefits To Choose Payday Loans In Serious Financial Difficulty! - 0 views

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    There are many situations faced by individual in his/her life that ask one to arrange quick money. In most cases, people ask help from their family and friends but at times they also can't provide the needed help.
Erich Feldmeier

Meaghan Christian: Family meals can help children reach their 5 A Day: a cross-sectiona... - 0 views

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    "The CADET tool found that children consumed on average 293 g F&V (95% CI 287 to 303) per day. Clustered (by school) multilevel regression models with total F&V as the primary outcome were conducted to explore how the home environment affects children's F&V intake. Children of families who reported 'always' eating a family meal together at a table had 125 g (95% CI 92 to 157; p=
Erich Feldmeier

Cory Abate-Shen: A Molecular Signature Predictive of Indolent Prostate Cancer - 0 views

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    Many newly diagnosed prostate cancers present as low Gleason score tumors that require no treatment intervention. Distinguishing the many indolent tumors from the minority of lethal ones remains a major clinical challenge. We now show that low Gleason score prostate tumors can be distinguished as indolent and aggressive subgroups on the basis of their expression of genes associated with aging and senescence. Using gene set enrichment analysis, we identified a 19-gene signature enriched in indolent prostate tumors. We then further classified this signature with a decision tree learning model to identify three genes-FGFR1, PMP22, and CDKN1A-that together accurately predicted outcome of low Gleason score tumors. Validation of this three-gene panel on independent cohorts confirmed its independent prognostic value as well as its ability to improve prognosis with currently used clinical nomograms. Furthermore, protein expression of this three-gene panel in biopsy samples distinguished Gleason 6 patients who failed surveillance over a 10-year period. We propose that this signature may be incorporated into prognostic assays for monitoring patients on active surveillance to facilitate appropriate courses of treatment.
Skeptical Debunker

A mini-laboratory for all cases - Research News 03-2010-Topic 5 - Fraunhofer-Gesellschaft - 0 views

  •  »We’ll just have to wait for the results of the laboratory tests.« These words are familiar to many patients. It then usually takes several days for specimens to be sent to the laboratory and analyzed and for the doctor to receive the results. For many illnesses, however, a speedy diagnosis is crucial if the treatment is to be successful. In future, the patient might only have to sit in the waiting room for a few minutes until the results are ready. In a joint project, researchers from seven Fraunhofer institutes have developed a modular platform for in vitro diagnosis which enables various types of bioanalysis – of blood and saliva for example – to be conducted in the doctor’s surgery. »Thanks to its modular design our IVD platform is so flexible that it can be used for all possible bioanalytical tasks,« states Dr. Eva Ehrentreich-Förster from the Fraunhofer Institute for Biomedical Engineering (IBMT) in Potsdam-Golm.The core element of the mini-laboratory is a disposable cartridge made of plastic which can be fitted with various types of sensor. For an analysis the doctor fills the cartridge with reagents – binding agents which indicate the presence of certain substances such as antigens in the specimen material. Various tests or assays are available for different types of analysis. To perform an assay, the doctor only has to place the relevant substances in the cartridge and the test then takes place automatically. »We have optimized the assays so that up to 500 assay reactions can be conducted in parallel in a single analysis step,« explains Dr. Ehrentreich-Förster. Even in the case of complex analyses the doctor obtains a result within about 30 minutes. A new module on the reverse side of the cartridge also makes it possible to analyze the specimen material at DNA level.Once the cartridge has been prepared, the doctor places it in the measurement system. The results can be read out with either optical or electrochemical biosensors. The researchers have installed a readout window for both methods in the measurement system, which features a bypass through which the specimen is pumped.
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    Many illnesses can be reliably diagnosed through laboratory tests, but these in vitro analyses often use up valuable time. A system developed by Fraunhofer research scientists, which can carry out complex analyses on the spot, will soon be ready for the market.
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