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What is it that makes the Internet so compelling to so many? Aside from the obvious fun and entertainment, educational and business opportunities, and show-offism; I think it boils down to a slogan taken from the eighties. No fear! The playing field is level. Size doesn't matter, really. Inhibitions and reservations are out the window. Internet life is people with diseases and addictions, exposing souls and sharing their recoveries. It's about overviews of history warning future generations not to repeat the mistakes of their predecessors. Sure there are a few kooks to throw us off guard, but mostly the Net is just us being ourselves without fear of reprisal. How refreshing. The Internet is people talking and sharing ideas. Our best and brightest, wallflowers and flower children, the girl next door and the Doc who delivered your kids. It's about you and me. We are all using our own cognizant voices, and we're listening too. We're challenging the status quo, and we're offering alternatives. Collaboration on a global scale all tied together by that simplest of cyber friendships, the hyperlink. Communication has never seen anything like it. I first considered all this ten years ago when that sociology study came out. Another ten years later, my life is even more enriched by the Internet. So to answer your question, I don't think it's the Internet that has whacked your brain, I think you might want to be looking elsewhere. If anything, the Internet is keeping you stimulated.

But some people, no matter how robust their stock portfolios or how healthy their children, are always mentally preparing for doom. They are just born worriers, their brains forever anticipating the dropping of some dreaded other shoe. For the past 20 years, Kagan and his colleagues have been following hundreds of such people, beginning in infancy, to see what happens to those who start out primed to fret. Now that these infants are young adults, the studies are yielding new information about the anxious brain.

Four significant long-term longitudinal studies are now under way: two at Harvard that Kagan initiated, two more at the University of Maryland under the direction of Nathan Fox, a former graduate student of Kagan’s. With slight variations, they all have reached similar conclusions: that babies differ according to inborn temperament; that 15 to 20 percent of them will react strongly to novel people or situations; and that strongly reactive babies are more likely to grow up to be anxious.

In the brain, these thoughts can often be traced to overreactivity in the amygdala, a small site in the middle of the brain that, among its many other functions, responds to novelty and threat. When the amygdala works as it should, it orchestrates a physiological response to changes in the environment. That response includes heightened memory for emotional experiences and the familiar chest pounding of fight or flight. But in people born with a particular brain circuitry, the kind seen in Kagan’s high-reactive study subjects, the amygdala is hyperreactive, prickly as a haywire motion-detector light that turns on when nothing’s moving but the rain. Other physiological changes exist in children with this temperament, many of them also related to hyperreactivity in the amygdala. They have a tendency to more activity in the right hemisphere, the half of the brain associated with negative mood and anxiety; greater increases in heart rate and pupil dilation in response to stress; and on occasion higher levels of the stress hormones cortisol and norepinephrine.