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This flipped case study is formatted as a PowerPoint presentation that uses group experimentation to encourage active learning in a large science classroom. There are options for using either wet bench experimentation or an online simulation, depending on the class goals. Students learn about plant transpiration and how it affects normal plant processes (photosynthesis). The basics of transpiration are covered in an animated video viewed outside of class. The experiment and/or simulation of transpiration can be conducted in or out of class. If the class is very large, the instructor may choose to assign the experiment/simulation for outside of class (post-video) and have the students bring their data to class, or the instructor may choose to just present the students with a data set from which they can work with their groups in class. At the end, students should be able to define transpiration, explain climate effects on transpiration rates, and how transpiration rates affect the overall physiology of the plant itself, through their own hypothesis design and experimentation.

Simulators which display cummulative generation graphs for variables.  Very cool data rich resource!  Includes Carbon cycle, demographis (human populations), Disease transmission, ecology, and energy simulations.

The Miller-Urey experiment was the first attempt to scientifically explore ideas about the origin of life. Stanley Miller simulated conditions thought be common on the ancient Earth. The purpose was to test the idea that the complex molecules of life (in this case, amino acids) could have arisen on our young planet through simple, natural chemical reactions. The experiment was a success in that amino acids, the building blocks of life, were produced during the simulation. The finding was so significant that it kick started an entirely new field of study: Prebiotic Chemistry. Scientists now have reason to believe that the gases used in the Miller-Urey simulation were not actually the same as those of the ancient atmosphere. Because of this, many experiments have since been done, testing a wide variety of atmospheres and different environmental conditions. The results are overwhelming: the molecules of life can form under a wide variety of ancient Earth-like conditions. Many questions about the origin of life remain to be answered but these findings give strong support to the idea that the first living cells on Earth may have emerged from natural chemical reactions.

Data rich simulation where students adjust parameters and run simulator for 100 iterations and see how 1) two plant species compete for a niche or 2) how composition of a food web changes over time Links to online textbook, videos, visuals, scientists.

This PowerPoint-driven case study follows the progress of three undergraduate students as they attempt to model the rapid spread of an influenza outbreak to determine whether their local newspaper's claim that "40% of the campus has the flu" is accurate. The case introduces epidemiological modeling using a base model for a seasonal influenza outbreak written in the NetLogo programmable modeling environment. In class, students develop tests for the various parameters of the model, run simulations, and evaluate the output. The students then explore the impact of influenza control strategies (vaccination, isolation, and antiviral medications), and finish with the question of whether the continuing outbreak on campus could be a pandemic. The case is written at a basic level for a lower-level undergraduate lecture-style class, but can be adapted to upper-level courses as well. The case was piloted in four different microbiology courses. The simulations stimulated active discussion and the content worked well, whether it was used in a pre-nursing microbiology or upper-level immunology class.

This case study centers on an active teaching game that simulates a cholera outbreak among five villages along a river, similar to the Haitian outbreak of 2010. By enacting the behaviors of fictional villagers, students learn how trade, travel, sanitation practices and geographic location contribute to the spread of diarrheal disease. Documenting various contamination events of village water supplies allows students to trace the progression of the disease and illustrates how adequate sanitation facilities provide protection against the bacteria Vibrio cholera. Originally designed for an undergraduate upper-division biology course focusing on the epidemiology of diseases, the simulation is also appropriate for microbiology and public health courses, as well as lower division undergraduate biology courses and high school. Biology or epidemiology components of the case study can be highlighted depending on the emphasis of the course being taught. The game can be completed within a 45- to 60-minute class period. Playing cards are available from the Supplemental Materials tab; detailed instructions are found in the teaching notes.

Earlier this week, the space agency released a new simulation created with this model, called GEOS-5, that shows clouds of carbon dioxide, a key driver of global warming, drifting far from their original sources - turning local greenhouse gases into global problems.

She wanted to understand the effects of mutations that the gene for p53 is prone to. In dozens of simulations, she and her colleagues tracked how common p53 mutations further destabilize the already floppy protein, distorting it and preventing it from binding to DNA. Some simulations also revealed something else: a fingerhold for a potential drug. Once in a while, a small cleft forms in the mutated protein's core. When Amaro added virtual drug molecules into her models, the compounds lodged in that cleft, stabilizing p53 just enough to allow it to resume its normal functions.

"This case study uses a PowerPoint presentation to guide students through two activities designed to teach them about the basics of coronavirus diagnosis and transmission. The first activity involves a set of five "clicker questions" that students answer using either a personal response system, online polling application, or show of hands as they consider symptoms and test results of a hypothetical patient. The second activity is an outbreak simulation in which students consider the spread of a pathogen in various geographical settings and from different perspectives. Students work together to draft a list of precautions that could be taken to limit the spread of the disease and minimize healthy individuals' risk of contracting it. The simulation is designed for a biology lesson pertaining to outbreaks. Although coronavirus is used as the model, the concepts of disease transmission and prevention covered in this case are relevant to many diseases."

Our teaching and learning environments have changed quite rapidly this semester! This page provides a (growing) list of free virtual labs and simulations. See the "Finding OER" tab for freely available textbooks and other course materials. If you find or create a resource to share, please email Emily Bongiovanni (emilybongiovanni@mines.edu) to have it added to the page.

An innovative new breeding simulation helps reveal genetic ratios in offspring. With the heredity level of the ConnectedBio Multi-Level Simulation (MLS), students breed pairs of mice with different fur colors and observe the phenotypic ratios in the resulting offspring. The goal of this activity is to demystify the science behind Punnett Squares and encourage students to explore data and statistical representations in genetics and heredity.

Teachers: the files here are only a sampling of possible virtual lab assignments. You are welcome to use the simulations however you see fit for your classroom and students.

The goal of RI-ITEST is to prepare diverse students for careers in information technologies by engaging them in exciting, inquiry- based learning activities that use sophisticated computational models in support of a revolutionary science curriculum. Teachers will incorporate interactive computer models developed under the Science of Atoms and Molecules (SAM) project at the Concord Consortium. These materials were specifically designed to support a deeper understanding of science made possible through interactive computer simulations and the new physics-chemistry-biology sequence. Connections will be made between the models students use to learn science and possible careers in research and industry where computer modeling is used.

Recombinant DNA technology for  human insulin AAT for emphysema GMOs for commercial value or simulate human conditions in animal models.

This case study is based on the 2014 Ebola epidemic that spread to multiple highly populated countries in West Africa, making it the largest and most devastating outbreak in the history of the virus. The storyline, inspired by a compilation of factual information, unfolds through a fictional narrative wherein students play the role of an infectious disease specialist in training to learn about the techniques used in the detection, diagnosis, and management of Ebola virus outbreaks. The story is presented as an interrupted "clicker case" that combines problem-based case teaching methods with simulated biological laboratory inquiry through the use of Case It, a free molecular biology software, along with the NCBI's online bioinformatics tools and databases. Students work in groups to collaboratively explore various biological and social aspects of this infectious disease outbreak. This case was developed for senior students at the secondary level and can be modified for use in an introductory biology, microbiology, or epidemiology course at the undergraduate level.

On this page we have compiled resources for educators to use in the classroom.  The first section consists of modules developed at NESCent.  "Other Curriculum Resources" includes a list of various resources ranging from single lessons, to books, to computer simulations.  The "Audio and Video Lecture" section has links to single lectures, interviews, and science shows.  Some are are audio only while others include video. 

Many of these labs allow students to test multiple variables. Caution: the journal and data entry sections of the simulations do not work, so you probably will want to arrange for students to write these on their own pages. Many of these labs are useful to substitute for activities in the class that are too costly, dangerous, or time consuming. I have assigned grades to some that I've explored in detail. Grades are based on interactivity, useability, and overall value of the exploration. Many of these can be used as simple class demonstrations, whereas others are more useful for having students explore and change variables.

These 106 in-depth tutorials are designed to illustrate and explain some of the many complex topics in biology. Each tutorial has four elements: an introduction that describes the topic to be illustrated and puts it into a broader context, a detailed animation that clearly illustrates the topic (there are a few tutorials that include simulations or other types of content, rather than animations), a conclusion that summarizes what you should have learned from the animation, and a quiz on the topic covered.

drag and drop review and comparison of plant and animal cells