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The Air Force Office of Scientific Research (AFOSR) seeks unclassified proposals for broad-based research and development aimed at using lasers and other light source technology to develop applications in medicine, photobiology, surgery, and closely related materials sciences, with applications to combat casualty care and other military medical problems. This announcement is primarily directed toward university-based medical institutions; however, all qualified and responsible prime applicants located in the United States are eligible to submit proposals. The highest priority will be extended to proposals up to three (3) years duration to be conducted by teams of physicians, biomedical scientists, physical scientists, and engineers. The efforts proposed may be basic or applied research, and must have direct relevance to combat casualty care or other military medical priorities. Applicants must demonstrate substantial experience working to further military medical priorities, including transitioning research into clinical practice and working products. Substantial experience collaborating with military medical centers is also a requirement to establish relevance to combat casualty care or other military medical priorities, and facilitate the transition of research results to meet military needs. Applicants are encouraged to apply as early as practicable. Proposals may be reviewed and selected as received. Awards may take the form of grants or contracts

The Air Force Office of Scientific Research (AFOSR) seeks unclassified proposals for research and development aimed at using lasers and other light source technology to develop applications in medicine, photobiology, surgery, and closely related materials sciences, with applications to combat casualty care and other military medical problems. This announcement is for a small number of individual awards. It is complementary to ongoing and future planed broad based awards, primarily directed toward university-based medical institutions, conducted by teams of physicians, biomedical scientists, physical scientists, and engineers. The efforts proposed may be basic or applied research, and must have direct relevance to combat casualty care or other military medical priorities. They must offer unique capabilities, not substantially funded by other DOD or other agency programs. Applicants must demonstrate substantial experience working to further military medical priorities, including transitioning research into clinical practice and working products. Substantial experience collaborating with military medical centers is also a requirement to establish relevance to combat casualty care or other military medical priorities, and facilitate the transition of research results to meet military needs.

The TriService Nursing Research Program (TSNRP) was founded in 1992 and funds and supports rigorous scientific research studies and evidence-based practice (EBP) projects in the field of military nursing. TSNRP is located within the Uniformed Services University of the Health Sciences (USU) which is authorized by 10 USC 2113(g)(1)(A) to make grants to any nonprofit entity for the purpose of carrying out cooperative enterprises in medical research, medical consultation, and medical education. TSNRP supports nurse scientists in all stages of their careers through research funding, education, and mentoring. Since its inception, TSNRP has funded over 430 research and EBP projects; 19 applications were successfully funded in Fiscal Year 2016. The mission of TSNRP is to facilitate nursing research to optimize the health of military members and their beneficiaries, with the following the five strategic goals: 1. Advance a culture of scientific inquiry and scholarly knowledge application. 2. Advocate mission critical priorities by building a military nursing research science base. 3. Expand infrastructure to support and develop nursing research and EBP. 4. Invest in military nurse scientists and programs of research. 5. Foster interservice nursing research capacity.

The U.S. Army Medical Research and Materiel Command's (USAMRMC) mission is to provide solutions to medical problems of importance to the American Service member at home and abroad, as well as to the general public at large. The scope of this effort and the priorities attached to specific projects are influenced by changes in military and civilian medical science and technology, operational requirements, military threat assessments, and national defense strategies. The extramural research and development programs play a vital role in the fulfillment of the objectives established by the USAMRMC. General information on USAMRMC can be obtained at https://mrmc.detrick.army.mil/. This Fiscal Year 2015 (FY15) Broad Agency Announcement (BAA) is intended to solicit extramural research and development ideas and is issued under the provisions of the Competition in Contracting Act of 1984 (Public Law 98-369), as implemented in Federal Acquisition Regulation (FAR) 6.102(d)(2) and 35.016. In accordance with FAR 6.102, projects funded under this BAA must be for basic and applied research and that part of development not related to the development of a specific system or hardware procurement. Projects must be for scientific study and experimentation directed toward advancing the state-of-the-art or increasing knowledge or understanding rather than focusing on a specific system or hardware solution. Research and development funded through this BAA is intended and expected to benefit and inform both military and civilian medical practice and knowledge. This FY15 BAA is continuously open for a 12-month period, from October 1, 2014 through September 30, 2015, at 11:59 p.m. Eastern Time. Submission of a pre-proposal/pre-application is required and must be submitted through the new electronic Biomedical Research Application Portal (eBRAP) (https://eBRAP.org/). Pre-proposal/pre-applications may be submitted at any time throughout the 12-month period. If the USAMRMC is interested in rece

mportant aspects of this award mechanism include: * Impact: Applications should articulate both the short- and long-term impact of the proposed research. Projects must address one or more of the FY19 SCIRP IIRA Focus Areas. * Relevance to Military Health: Projects should be relevant to spinal cord-injured military Service members, Veterans, and/or their family members and caregivers. Collaboration with military and VA researchers and clinicians is encouraged. * Preliminary Data: Observations that drive a research idea may be derived from laboratory discovery, population-based studies, a clinician's first-hand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to the mission of the SCIRP and support the proposed research project. IIRA applications may focus on any phase of research from basic through translational. Permitted research includes preclinical studies in animal models, research with human subjects, or human anatomical substances, as well as ancillary studies associated with an existing clinical trial. Applications including animal studies must include a clear justification for the animal model chosen including relevance to human SCI.

DHAPP's goal is to maximize program impact by focusing on the drivers of the HIV epidemic specific to the military and to support the development of interventions and programs that address these issues. DHAPP works with militaries of foreign countries to devise plans

 Impact: Applications should articulate both the short- and long-term impact of the proposed research. Projects must address one or more of the FY18 SCIRP IIRA Focus Areas.  Military Relevance: Projects should be relevant to spinal cord-injured military Service members, Veterans, and/or their family members and caregivers. Collaboration with military and VA researchers and clinicians is encouraged.  Preliminary Data: Observations that drive a research idea may be derived from laboratory discovery, population-based studies, a clinician's first-hand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to the mission of the SCIRP and the proposed research project. IIRA applications may focus on any phase of research from basic through translational. Permitted research includes preclinical studies in animal models, research with human subjects, or human anatomical substances, as well as correlative studies associated with an existing clinical trial.

The SCIRP IIRA is intended to support studies that have the potential to make an important contribution to SCI research, patient care, and/or quality of life. Important aspects of this award mechanism include: * Impact: Applications should articulate both the short- and long-term impact of the proposed research. Projects must address one or more of the FY20 SCIRP IIRA Focus Areas. * Relevance to Military Health: Projects should be relevant to spinal cord-injured military Service members, Veterans, and/or their family members and care partners. Collaboration with military and VA researchers and clinicians is encouraged. * Preliminary Data: Observations that drive a research idea may be derived from laboratory discovery, population-based studies, a clinician's first-hand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to the mission of the SCIRP and support the proposed research project

The mission of the MHRP is to protect military personnel from HIV and other emerging infectious diseases and improve global health by conducting research to develop vaccines, prevent new infections, and find cures. In support, the goals of the MHRP are as follows: · Build on RV144 (Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009 361(23):2209-2220) and execute an integrated vaccine development program. · Lead the field in acute infection and cure research. · Integrate MHRP's continuum of discovery, preclinical, and clinical research. · Perform clinical and population health research. · Strengthen external partnerships and enhance collaboration across the DoD. · Leverage MHRP's international capacity for research, clinical development, prevention, care, and treatment to advance national security and global health objectives. · Generate and translate diagnostic and knowledge products to inform health policy and reduce the burden of infectious diseases in the military. · Support professional development of military and civilian infectious disease research staff in order to build the next generation of scientific leaders.

The MBRP Clinical Trial Award mechanism is being offered for the first time in FY17.The objective of this Program Announcement is to explore innovative approaches to accelerate the translation of knowledge advances into new treatments for the Service members who sustain burn injuries. The results of the research funded through the FY17/18 MBRP Clinical Trial Award are expected to increase the body of knowledge and materiel products available to professionals and practitioners in health, medical science, and related fields. The research impact is expected to benefit both civilian and military communities.The FY17/18 MBRP Clinical Trial Award supports clinical research studies with the potential to have a major impact on the prevention, treatment, and mitigation of debilitating burn scars that are relevant to military personnel. The specific intent is to improve functional outcomes and/or assess clinical efficacy and safety of different treatment modalities (e.g., dressing topics, biologics, cell-based therapies, mechanical, photonics).

The U.S. Army Medical Research and Materiel Command's mission is to responsively and responsibly create, develop, deliver, and sustain medical capabilities for the Warfighter. The AIMM initiative was created to accelerate transformational biomedical research for our Armed Forces and Nation. The mission of the AIMM initiative is to encourage, identify, and enable innovative research that leads to cross-cutting solutions to military health threats. The AIMM Research Award is intended to support highly creative and conceptually innovative high-risk research with the potential to accelerate critical discoveries or major advancements that will significantly impact military health and medicine. AIMM initiative funding supports novel research concepts and other efforts that initiate or enhance potential game-changers that may not be supported by other funding mechanisms or core programs.

Infectious diseases have negatively impacted U.S. military operations dating as far back as the Revolutionary War. Recent outbreaks of Ebola, Chikungunya and Zika combined with the ongoing threats posed by malaria, infectious diarrhea and multi-drug resistant bacteria in regions where U.S. military personnel operate underscore the need for preventive measures to mitigate against the impact that infectious diseases have on the operational forces of the U. S. The goal of this Cooperative Agreement is to engage in a collaborative research and development (R&D) effort for protective vaccines and other countermeasures targeting the causative agents of malaria, travelers' diarrhea, rickettsial pathogens, multi-drug resistant bacteria, and emerging viral diseases.

Career Development Award supports early-career, independent investigators to conduct impactful research under the mentorship of an experienced lung cancer researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of lung cancer research. This award is intended to support impactful research projects with an emphasis on discovery. Submissions from and partnerships with investigators at military treatment facilities, military labs, and Department of Veterans Affairs (VA) medical centers and research laboratories are strongly encouraged.Preliminary data are not required. However, logical reasoning and a sound scientific rationale for the proposed research must be demonstrated.Key elements of this award are as follows.

The Idea Development Award promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress toward eradicating deaths from lung cancer. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale. Submissions from and partnerships with investigators at military treatment facilities, military labs, and Department of Veterans Affairs (VA) medical centers and research laboratories are strongly encouraged. New Investigators: The FY16 Idea Development Award mechanism encourages applications from independent investigators in the early stages of their careers (i.e., within 10 years of their first faculty appointment, or equivalent). The New Investigator category is designed to allow applicants early in their faculty appointments to compete for funding separately from established investigators. Applications from New Investigators and Established Investigators will be peer and programmatically reviewed separately. Principal Investigators (PIs) using the New Investigator category are strongly encouraged to strengthen their applications by collaborating with investigators experienced in lung cancer research and/or possessing other relevant expertise. It is the responsibility of the applicant to describe how the included collaboration will augment the PI's expertise to best address the research question. All applicants for the New Investigator category must meet specific eligibility criteria as described in Section I.D., Eligibility Information. Preliminary data to support the feasibility of the research hypotheses and research approaches are required; however, these data do not necessarily need to be derived from studies of lung cancer.

The Program is pleased to announce that it is seeking proposals for funding to support forensic and biometric research and its application. The requested proposals should focus on DFBA activities and needs of the Program's other customers (AFMES, DC3, JPAC-CIL). Forensic research proposals should focus on the creation of new and improved field or laboratory functional capabilities that result in faster, more robust, more informative, less costly, or less labor-intensive recognition, identification, collection, preservation, and/or analysis of forensic evidence. Biometric research proposals should contribute to biometric applications or operations, including military functions such as combat identification (friend, foe, or neutral), offensive operations (intelligence support to targeting), force protection (physical access control), detention operations, civil-military operations (track target members of a population), personnel recovery and identification, and recognition and recovery of human remains. Proposals that will assist the DoD in achieving these goals are solicited, particularly proposals involving the development of equipment that is portable, sustainable, and useful in an expeditionary or field environment. The expeditionary and field environments require systems that are lightweight, portable, inexpensive, fast, and capable of operating in extreme environments of temperature, dust, humidity, etc. The systems must also be capable of secure data communications.

The PH/TBIRP Long-Term Impact of Military-Relevant Brain Injury Consortium (LIMBIC) Award is being offered for the first time in FY18. The overarching goal of this effort is to improve our understanding of the impact of mild TBI (mTBI)/concussion on Service members and Veterans. The FY18 PH/TBIRP LIMBIC Award will support a Consortium conducting a single large longitudinal study and associated sub-studies within the scope of the Program Announcement/Funding Opportunity. The knowledge gained through the proposed studies will be used to inform TBI pathways of care and illuminate specific target areas to improve acute TBI care and subsequent support systems for chronic care following mTBI.

On September 13, WBI will be hosting its 3rd OEA Collider Event, this time on the topic of Human Performance Enhancement. Please block your calendars from 1:30 till 3:30 and plan to join us to learn more about the opportunities within this massive market space. For the purposes of this project, we're defining Human Performance Enhancement like this: As the world becomes more complex, the demands on human performance continue to increase. Athletic endeavors, military requirements, continuing independence into one's later years are all examples of market-driven needs for human performance enhancement. Strength, speed, endurance, vigilance, multi-tasking, mental-acuity, and recovery are all enhancement opportunities of interest. Formal evaluation of blue papers will begin on approximately 17 October 2016. Wright Brothers Institute continues to work diligently on our pilot project to refine a commercialization process for regional innovators. In March we had an OEA Collider event focused on the Precision Agriculture market which has resulted in 8 Blue Paper submissions and 2 on-going projects to commercialize several of the concepts explained in those blue papers. We're making significant progress toward providing real market solutions with a combination of several innovative technologies!

On September 13, WBI will be hosting its 3rd OEA Collider Event, this time on the topic of Human Performance Enhancement. Please block your calendars from 1:30 till 3:30 and plan to join us to learn more about the opportunities within this massive market space. For the purposes of this project, we're defining Human Performance Enhancement like this: As the world becomes more complex, the demands on human performance continue to increase. Athletic endeavors, military requirements, continuing independence into one's later years are all examples of market-driven needs for human performance enhancement. Strength, speed, endurance, vigilance, multi-tasking, mental-acuity, and recovery are all enhancement opportunities of interest. Formal evaluation of blue papers will begin on approximately 17 October 2016. Wright Brothers Institute continues to work diligently on our pilot project to refine a commercialization process for regional innovators. In March we had an OEA Collider event focused on the Precision Agriculture market which has resulted in 8 Blue Paper submissions and 2 on-going projects to commercialize several of the concepts explained in those blue papers. We're making significant progress toward providing real market solutions with a combination of several innovative technologies!

The National Research Action Plan (NRAP) responding to Executive Order 13625, Improving Access to Mental Health Services for Veterans, Service Members, and Military Families (August 31, 2012), lays out a framework to ensure that Government funding agencies work together to further our knowledge and diagnostic/therapeutic capabilities with regard to post- traumatic stress disorder (PTSD), TBI, suicide, and related injuries by following longitudinal cohorts of Service members and Veterans. The DoD and VA ORD meet this directive through continued collaboration on and coordination of research efforts in the areas of TBI and PTSD. Additionally, recommendations from the DoD Blast Injury Research Program Coordinating Office's November 2015 International State of the Science Meeting (Does Repeated Blast- Related Trauma Contribute to the Development of Chronic Traumatic Encephalopathy (CTE)?) included pursuing longitudinal studies to evaluate links between blast-related TBI with CTE. While a number of longitudinal efforts are ongoing, the DoD and VA seek to pursue a mechanism to collaboratively streamline and continue longitudinal studies of mTBI in active duty and Veteran populations. The objective of this effort is to solicit a single Consortium of a large longitudinal study and supporting sub-studies to analyze a large TBI cohort to include Service members, Veterans, and relevant populations.

Infectious diseases have negatively impacted U.S. military operations dating as far back as the Revolutionary War. Recent conflicts and outbreaks involving infectious agents such as Ebola, Chikungunya and Zika underscore the need for preventive measures to mitigate the effects on operational forces of the U. S. The goal of this Cooperative Agreement is to engage in a collaborative research and development (R&D) effort to devise protective vaccines and other countermeasures targeting the causative agents of malaria, travelers' diarrhea, rickettsial pathogens and emerging viral diseases. Research will also focus on developing novel countermeasures targeting multi-drug resistant bacteria that are associated with combat related wound infections.

The intent of the research funded through this award is to (1) support research to alleviate, stabilize, or characterize the symptoms or deficits common to TBI and AD/ADRD, and (2) reduce the burden of care on the caregiver for individuals living with the common symptoms of TBI and AD/ADRD. Research may be proposed to either facet of the intent. Both are equally important. As part of the research strategy, all applications must include cognitive, neuropsychological, or otherwise appropriate measures.The FY17 PRARP QUAL is open to Principal Investigators (PIs) at or above the level of Assistant Professor (or equivalent) from any field or discipline. As part of the application, the PI should demonstrate that the study team has experience in both TBI and AD/ADRD research. Preliminary data, while not required, are encouraged. Preliminary data may come from the PI's published work, pilot data, or from peer-reviewed literature. Applications should also address how all of the included study measures address the research strategy and the study's hypothesis or hypotheses.The anticipated direct costs budgeted for the entire period of performance for an FY17 PRARP QUAL will not exceed $500,000. The maximum period of performance is 3 years. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.The research impact is expected to benefit the military, Veteran, and civilian communities. To this end, the PRARP has identified QUAL Overarching Challenges and Focus Areas by which the intent of this mechanism can be facilitated. These should be carefully considered as part of the application process.FY17 PRARP QUAL Overarching Challenges: T