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Fellowship Announcement | The Matsumae International Foundation - 0 views

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    Eligibility Requirements:
    Applicants of non-Japanese nationality; a Doctorate degree; must be 49 years old or under;  not have been in Japan previously; have firm positions and professions in their home nations; etc.

    Host Institution In Japan:
    Applicants are free to select host institutions (university research laboratories, national research institutions or the corresponding facilities of private industry)

    Fellowship Details:
    Stipend for research and stay, Insurance, Air transportation (a round-trip air ticket to/from Tokyo) and Lump sum on arrival

    Period & Number of Fellowships:
    For a period of from three to six months; the number of fellowships is about 20 persons each year.
MiamiOH OARS

Limited Competition: AIDS and Cancer Specimen Resource (ACSR)(UM1 Clinical Trials Not A... - 0 views

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    Through this limited competition Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) solicits a single application for the continuation of the AIDS and Cancer Specimen Resource (ACSR). The eligible applicant institutions (which are the two current NCI-supported ACSR lead institutions) are expected to maintain the cooperative group structure and the activities of the ACSR. The primary objective of the ACSR will be to acquire, store, and equitably distribute tumor tissues, biological fluids, and associated demographic data from patients with human immunodeficiency virus (HIV)-associated malignancies. In addition to serving acquired immunodeficiency syndrome (AIDS) and cancer researchers at large, the ACSR will specifically provide biorepository functions for another NCI supported initiative, the AIDS Malignancy Consortium (AMC). The AMC performs clinical trials research in the treatment and prevention of HIV-associated malignancies in the United States and Sub-Saharan Africa. As the AMC is currently expanding its agenda to include Latin America, it is expected that the ACSR will collaborate with the AMC to develop regional biorepository support for AMC activities in Latin American countries. The continuing ACSR must have appropriate strategies and capabilities to address several high priority areas of specimen acquisition including specific types of cancer (AIDS-defining as well as non-AIDS defining), types of biospecimens and accompanying clinical data, and biospecimens from geographic areas of interest.
MiamiOH OARS

Computationally-Defined Behaviors in Psychiatry (R21 Clinical Trial Optional) - 0 views

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    This Funding Opportunity Announcement (FOA) solicits proposals for research projects that will apply computational approaches to develop parametrically detailed behavioral assays across mental-health relevant domains of function. These projects should focus on behavior in humans and test computational models in healthy subjects. For future applications, NIMH is particularly interested in behavioral measures, models, and parameters that have the potential for back-translation from humans to animals, especially for pre-clinical therapeutics development. NIMH is also interested in models that can be extended to clinical populations in the future.
MiamiOH OARS

Elucidating the Role of the Autonomic Nervous System in Peripheral Metabolism and Metab... - 0 views

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    This is a Task Agreement under a Youth Master Cooperative Agreement P15AC00031. The Recipient with recruit 2 interns. The purpose of this project is to provide youth hands-on experience in natural and cultural restoration and toenhance the scientific communities knowledge adding to the study/ monitoring of bats. This is in regards to the White Nose Syndrome (WNS),a deadly disease that affects North American bats. The work done by the interns will help the management and provide for public awareness. The primary goal is to continue with a landscape project involving 22 acres that was started in 2017.The objectives are to re-seed with native grasses and forbs.

    This project incorporates these public purposes: The information, products and/or services identified or developed by this project will be shared through a variety of strategies to increase public awareness, knowledge and support for historic preservation and stewardship of the nation's cultural and historical heritage.
    The principal purpose of the project is to support the Government's objective to provide opportunities for youth to learn about the environment by spending time working on projects in National Parks. The NPS receives the indirect benefit of completing conservation projects.
MiamiOH OARS

NLM Research Grants in Biomedical Informatics and Data Science (R01 Clinical Trial Opti... - 0 views

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    The National Library of Medicine (NLM) supports innovative research and development in biomedical informatics and data science. The scope of NLM's interest in these research domains is broad, with emphasis on new methods and approaches to foster data driven discovery in the biomedical and clinical health sciences as well as domain-independent, reusable approaches to discovery, curation, analysis, organization and management of health-related digital objects. Biomedical informatics and data science draw upon many fields, including mathematics, statistics, information science, computer science and engineering, and social/behavioral sciences. Application domains include health care delivery, basic biomedical research, clinical and translational research, precision medicine, public health, biosurveillance, health information management in disasters, and similar areas. NLM defines biomedical informatics as the science of optimal representation, organization, management, integration and presentation of information relevant to human health and biology. NIH defines data science as the interdisciplinary field of inquiry in which quantitative and analytical approaches, processes, and systems are developed and used to extract knowledge and insights from increasingly large and/or complex sets of data.
MiamiOH OARS

Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Asse... - 0 views

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    The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is seeking applications proposing research that will promote the development and use of alternative test methods and strategies that address the "3Rs" of toxicity testing: 1) reduce, 2) refine, and/or 3) replace vertebrate animal testing. For the purposes of this RFA, alternative test methods refer to those that incorporate the "3Rs" principles. Pertinent research includes approaches such as analog/read-across techniques, mathematical models, and tiered testing approaches that integrate evidence from multiple sources to help accomplish these goals. In addition to the development of new alternative test methods and strategies, translational science approaches that use available data to develop and/or advance actionable approaches for risk assessment of chemicals are also critical. In this context, approaches that facilitate the use of existing animal data sources to reduce, refine, or replace the need for new vertebrate animal tests are as welcome as those that provide new data streams. The research activities to be funded under this announcement are intended to advance the science underpinning the use of non-vertebrate test methods, and to develop actionable alternative approaches to: 1) developmental toxicity tests in humans; 2) reproductive toxicity tests in humans; and/or 3) ecotoxicity tests.
MiamiOH OARS

CNS-Targeted Drug Delivery Strategies for HIV (R01 Clinical Trial Not Allowed) - 0 views

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    The purpose of this Funding Opportunity is to support studies with a focus on developing drug delivery strategies that target the Central Nervous System (CNS) for better suppression of Human Immunodeficiency Virus (HIV) and reservoir reduction. Applications are sought proposing multidisciplinary efforts to enhance delivery of antiretroviral (ARV) drugs and biologics into CNS compartments, maintaining a good balance between therapeutic effect and toxicity. Collaborative research partnerships are strongly encouraged but not required.
MiamiOH OARS

Early Stage Drug Discovery Project Using a New Drug Discovery Underlying Technology 2c - 0 views

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    NineSigma, representing a Japanese leading pharmaceutical company, seeks drug discovery projects which make use of any of the following drug discovery underlying technologies and which are in a hit discovery stage. It is preferable that the research has already started; however, proposals are welcome also from an organization with plans to start a specific project in the future. The client aims to build a drug discovery platform, which is globally competitive, through collaboration with partners.

    The client can provide opportunities, depending on the R&D stage and the business plan of partners, and hopes not only to foster joint research and development, but also to maximize outcome creation by licensing, support with budget, etc. to support improvement of underlying technology.
MiamiOH OARS

Development Partner for Part of Next-generation Medical Balloon Catheters 2c - 0 views

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    NineSigma, representing a multi-billion-dollar medical instruments manufacturer, is looking for development partners to realize next-generation balloon catheters. The main development object involves balloon parts that act as components for balloon catheters. The client seeks technology that resolves the challenges of pressure resistance, flexibility, etc., and that is applicable to the field of medical instruments. The client also widely welcomes materials, structural designs, manufacturing methods, etc., that are used in other fields.
MiamiOH OARS

2aPowder Sterilization Technologies 2c - 0 views

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    PepsiCo seeks efficient and effective technologies to sterilize powdered seasonings without impacting performance characteristics
MiamiOH OARS

Low-cost solution for cryogenic temperature measurement 2c (deadline Sept. 29) - 0 views

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    A reliable and low-cost solution is required for measuring the temperature of components within a:

    Gaseous and liquid environment within a cryogenic helium vessel
    Vacuum vessel between the temperature range of 300-3K
    Magnetic fields up to 8T

    It may be acceptable for a solution to be proposed that can cover all the ranges of temperature however different solutions may also be considered for individual ranges if optimised solutions can be offered for some or all of the ranges.
MiamiOH OARS

Greenwall Foundation Invites Letters of Intent for Scholars Program | RFPs | PND - 0 views

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    The Greenwall Foundation is inviting Letters of Intent for its Greenwall Faculty Scholars Program in Bioethics, a career-development award designed to enable junior faculty members to carry out innovative bioethics research. The program supports research that goes beyond current work in bioethics to help resolve pressing ethical issues in clinical care, biomedical research, and public policy, and creates a community that enhances future bioethics research by Greenwall scholars and alumni/ae.

MiamiOH OARS

Genomic Innovator Award (R35 Clinical Trial Optional) - 0 views

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    This program supports highly creative individuals in NHGRI priority research areas, such as the development of resources, approaches, or technologies that will accelerate genomic research on the structure of genomes, the biology of genomes, or the biology of disease; that will advance the science of genomic medicine; that will incorporate genomics to improve the effectiveness of healthcare; or that will advance genomic technology development, computational genomics, or research on the ethical, legal, and societal implications of genomics and genetics research. 

    This program supports the development of approaches that can be used broadly.  A hallmark of genomic research is comprehensiveness across the genome, such as all genes, variants, or regulatory elements, rather than specific sets.  The focus should be on developing approaches that can be applied generally, although an approach may be tested with specific genes, genomic elements, variants, cell types, diseases, traits, or model organisms.  Studies that focus on one or a few specific genes should be paradigm-setting and yield findings relevant at the genomic level.  The application should explain how broadly useful the approaches will be.

MiamiOH OARS

Regenerative Medicine Innovation Projects (RMIP) Investigator-Initiated Clinical Trials... - 0 views

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    The National Institutes of Health (NIH) participating Institutes and Centers, in coordination with the U.S. Food and Drug Administration (FDA), seeks highly meritorious clinical trial applications proposing to explore and enable the development of safe and effective regenerative medicine (RM) interventions using adult stem cells. This Funding Opportunity Announcement (FOA), issued as part of the Regenerative Medicine Innovation Project (RMIP), represents one step in fulfilling a statutory provision set forth in the 21st Century Cures Act. Applications submitted in response to this bi-phasic, milestone-driven cooperative agreement FOA are expected to propose highly innovative projects with a focus on solutions to widely recognized issues in the development of safe and effective RM therapies. Of particular interest are projects using RM products that have undergone appropriate product development and pre-clinical studies and have demonstrated readiness to advance into clinical trials.

MiamiOH OARS

Management of Asthma in Primary Care - Bioinformatics Center (U24 - Clinical Trial Requ... - 0 views

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    The purpose of this U24 Funding Opportunity Announcement (FOA) is to support a bioinformatics group (BIG) that will analyze a set of asthma-specific common data elements (CDEs) retrospectively collected from the electronic health record data (EHR) of patients in the US whose asthma is managed by a primary care provider (PCP). Based on a large, nationally representative data set, the BIG will identify the current management practices (CMPs) of PCPs that result in the best asthma outcomes for specific groups of patients in different clinical settings or situations. The CMPs will be established by the BIG in collaboration with a clinical consultant team (CCT) with expertise in asthma and a primary care network (PCN), experienced in managing the primary care of patients. Following the BIG's analysis of retrospective data, the CCT and PCN will design and then conduct prospective clinical trials to compare the retrospectively identified CMPs in appropriate patients with asthma. At the conclusion of the clinical trials, the BIG will perform the data analysis for the assessment of the CMPs, refining any of the processes needed to analyze the asthma CDE data.
MiamiOH OARS

BRAIN Initiative: Development of Novel Tools to Probe Cell-Specific and Circuit-Specifi... - 0 views

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    The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative funding opportunity announcement is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis and manipulation of complex circuits in large brains. Critical advances in the treatment of brain disorders in human populations are hindered by our lack of ability to monitor and manipulate circuitry in safe, minimally-invasive ways. Clinical intervention with novel cell and circuit specific tools will require extensive focused research designed to remove barriers to delivery of gene therapies. In addition to identification and removal of barriers, the need to specifically target dysfunctional circuitry poses additional challenges. Neuroscience has experienced an impressive influx of exciting new research tools in the past decade, especially since the launch of the BRAIN Initiative. However, the majority of these cutting-edge tools have been developed for use in model organisms, primarily rodents, fish and flies. These cutting-edge tools, such as viral delivery of genetic constructs, are increasingly adaptable to larger mammalian brains and more importantly are emerging as potential human therapeutic strategies for brain disorders. A pressing need to develop tools for use in large brains or those that are more directly relevant to the human brain is the focus of this initiative. The initiative will support initial proof of principle studies aimed at demonstrating the feasibility of this approach in humans and other mammalian species (non-human primate [NHP]/sheep/pigs).
MiamiOH OARS

Early Psychosis Intervention Network (EPINET): Data Coordinating Center (U24 Clinical T... - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications for an Early Psychosis Intervention Network (EPINET) National Data Coordinating Center (ENDCC) to support and extend the work of regional scientific hubs described in companion announcement RFA-MH-19-150. The ENDCC will lead efforts to (a) harmonize early psychosis common data elements, standard measures, and uniform data collection procedures across multiple early psychosis Coordinated Specialty Care (CSC) clinics within regional networks; (b) build informatics infrastructure and pipelines necessary to gather and store de-identified, patient-level data collected across all regional clinics; (c) develop data analysis, presentation, and reporting tools to facilitate timely quality improvement and program evaluation efforts across regional networks; (d) identify innovative CSC assessment, intervention, and quality improvement practices for broad dissemination; and (e) make national CSC data available for practice-based research to improve early identification, diagnosis, clinical assessment, intervention effectiveness, service delivery and health outcomes in early psychosis. The ENDCC will combine regional datasets into a national repository of early psychosis common data elements, clinical measures, assessment and intervention strategies, and de-identified person-level data from patients receiving CSC services. Data assembled by the ENDCC will facilitate large-scale, practice-based research to improve early identification, diagnosis, clinical assessment, intervention effectiveness, and health outcomes in clinics offering evidence-based care to persons in the early stages of psychotic illness.

MiamiOH OARS

Discovery of Biomarkers, Biomarker Signatures, and Endpoints for Pain (R61/R33 Clinical... - 0 views

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    The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery of strong candidate biomarkers and endpoints for pain that can be used to facilitate the development of non-opioid pain therapeutics from discovery through Phase II clinical trials.  Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical validation of pain biomarkers, biomarker signatures, and/or endpoints. Although research supported by this FOA can include animal studies, it must also include preliminary human validation using carefully standardized human samples or human clinical studies. The goal of this initiative is to deliver candidate biomarkers, biomarker signatures, and/or endpoints that are ready for advanced clinical and analytical validation research.
MiamiOH OARS

Alzheimer Centers for Discovery of New Medicines (U54 Clinical Trial Not Allowed) - 0 views

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    This Funding Opportunity Announcement (FOA) invites U54 Cooperative Agreement applications aiming to establish multi-component Alzheimer Centers for the Discovery of New Medicines. The overarching purpose of this Centers program is to improve, diversify and reinvigorate the Alzheimer's disease (AD) drug development pipeline by accelerating the characterization and experimental validation of next generation therapeutic targets and integrating the targets into drug discovery campaigns. In addition, this program aims to de-risk potential therapeutics to the point that industry will invest in them, accelerating the delivery of new drugs to AD patients. To this end, the funded Centers will 1) design, develop and disseminate tools that support target enabling packages (TEPs) for the experimental validation of novel, next generation therapeutic targets, including those emanating from the NIA-funded, target discovery programs such as AMP-AD, and 2) initiate early stage drug discovery campaigns against the enabled targets.  
MiamiOH OARS

California State University Institute for Palliative Care Invites Seed Grant Applicatio... - 0 views

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    The funding is offered in conjunction with the theme of the National Symposium on Academic Palliative Care Education and Research, Quality in Palliative Care: Fusing Education, Research and Practice, being held in San Diego from October 11 to October 12, 2018. Multiple grants ranging between $5,000 and $10,000 will be awarded at the symposium. The institute encourages proposals for innovative educational and/or research projects that will expand current or future workforce knowledge leading to improved care or enhanced quality of life for seriously or chronically ill people.
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