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MiamiOH OARS

RFA-DK-17-019: Mass Spectrometric Assays for the Reliable and Reproducible Detection of... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing the development of targeted mass spectrometric assays (e.g. Multiple Reaction Monitoring) for proteins and peptides of primary interest to the type 1 diabetes research community (e.g. glucagon, somatostatin, C-peptide, insulin, and Glycated CD59). The proposed assays should be highly reproducible, easily transferable to other laboratories, easy to multiplex, and validated in human plasma or serum.
MiamiOH OARS

RFA-DA-19-003: Exploiting Omics Assays to Investigate Molecular Regulation of Persisten... - 0 views

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    This initiative will support projects that exploit Omics assays to address outstanding questions regarding molecular regulation of persistent HIV (e.g. latency or reservoirs) in the context of chronic substance use or substance use disorder (SUD).
MiamiOH OARS

PA-18-660: Genetics of Alcohol Sensitivity and Tolerance (R01 Clinical Trial Not Allowed) - 0 views

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    The National Institute on Alcohol Abuse and Alcoholism is publishing a Funding Opportunity Announcement (FOA) to seek applications on novel genetic mechanisms underlying the development of tolerance and the progression to alcohol use disorder. Alcohol use disorders are complex, multifactorial, and influenced both by genetic and environmental factors. The purpose of this FOA is to stimulate and support efforts on identifying genetic, genomic and epigenetic factors contributing to the development of sensitivity and tolerance to alcohol.
MiamiOH OARS

Nano-Bio Manufacturing Consortium (NBMC) - Federal Business Opportunities: Opportunities - 0 views

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    The Nano-Bio Manufacturing Consortium is expected to grow the US-centric innovation ecosystem that will risk reduce material supply (including nanomaterials & biomaterials), processing techniques, and flexible/stretchable device concepts by demonstrating component- and system-level functionality relevant to human-integrated technologies, such as airman-performance monitoring (APM) and augmentation (APA) systems. This public-private partnership should build upon the foundation of research & development excellence that has been established within NBMC since its 2013 inception.
    It is envisioned that technology development will require teaming between academia and industry in partnership with government researchers as well as with appropriate members of the regulatory and operational DoD communities. A balance between enabling component- and systems-level prototype development is expected to be realized through end-technologies between TRL 3 and TRL 6. It is expected that during the completion of certain NBMC projects, lab and/or field demonstrations will be conducted in partnership with relevant DoD partners to ensure that members of military human performance and/or aeromedical communities can assess the utility of developments and provide iterative feedback with respect to critical path issues.
MiamiOH OARS

Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Cli - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications for studies of etiology and pathogenesis related to development of type 1 diabetes (T1D) and/or its complications. Studies must involve subjects enrolled and followed in clinical trials, long term follow-up, or observational studies. This opportunity is intended to fund collaborative projects that bring new expertise and innovative approaches to enhance the value of major ongoing clinical research projects.
MiamiOH OARS

Career Development Programs in Diabetes Research for Endocrinologists (K12 Clin - 0 views

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    This Funding Opportunity Announcement is intended to foster the development of a diverse and highly trained workforce of endocrinologists to assume leadership roles related to the Nations biomedical and behavioral research efforts in the area of type 1 diabetes (T1D). T1D is an autoimmune disease that occurs in both children and adults. Therefore, the NIDDK will award physician scientist career development program (K12) grants to eligible institutions to provide a program to prepare adult and/or pediatric endocrinologists, selected by the institution, for careers in basic or clinical research related to T1D. This Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary study to an existing trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development. Scholars may also propose fundamental research or human subjects research that is not a clinical trial.
MiamiOH OARS

Clinical Validation of Candidate Biomarkers for Neurological Diseases (U01 Clinical Tr - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to support rigorous clinical validation of a candidate biomarker using retrospective and/or prospective methods in a manner that is consistent with the purpose of the biomarker. This FOA assumes that: 1) a candidate biomarker has already been identified, 2) an analytical method has been developed and validated that is consistent with the purpose of the biomarker and 3) a working hypothesis regarding context of use is in place. The goal of this FOA is to facilitate the advancement of robust and reliable biomarkers of neurological disease for use in multi-site clinical trials and clinical practice.
MiamiOH OARS

Research Options for Space Enterprise Technologies (ROSET) - 0 views

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    The Air Force Research Laboratory (AFRL) Space Vehicle Directorate (RV) is interested in receiving proposals from all offerors to advance state of the art technology and scientific knowledge supporting all aspects of space systems including payload adapters, on-orbit systems, communications links, ground systems, and user equipment. Efforts will include basic and advanced research, advanced component and technology development, prototyping, and system development and demonstration and will span the range from concept and laboratory experimentation to testing/demonstration in a relevant environment. Specific tasks include design, development, analysis, fabrication, integration, characterization, testing/experimentation, and demonstration of hardware and software products.
MiamiOH OARS

Genetics of Alcohol Sensitivity and Tolerance (R01 Clinical Trial Not Allowed) - 0 views

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    The goal of this FOA is to develop new hypotheses and common experimental framework(s) between human - animal model studies to better understand the genetic, genomic, and epigenetic factors contributing to and underlying biological bases for the development of tolerance and the progression to alcohol dependence.
MiamiOH OARS

Treating Diabetes Distress to Improve Glycemic Outcomes in Type 1 Diabetes (R01 Clinica... - 0 views

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    This FOA seeks applications for clinical trials testing interventions targeting diabetes distress in individuals with T1D and/or their caregivers, with the goal of understanding whether lowering diabetes distress will improve glycemic control and quality of life.
MiamiOH OARS

Immune System Engineering For Targeted Tolerance in Type 1 Diabetes (R01 Clinical T - 0 views

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    ype 1 diabetes (T1D) results in part from the autoimmune-mediated dysfunction or destruction of insulin-producing pancreatic beta cells. This funding opportunity is for projects that seek to discover ways to change the course of the disease by directly establishing tolerance. Immune responses could be engineered for tolerance induction through the manipulation of antigens, cells, or cellular microenvironments. Collaborations between T1D experts and investigators from other fields, including (but not limited to) cancer immunology and biomaterials engineering, are especially encouraged.
MiamiOH OARS

Mass Spectrometric Assays for the Reliable and Reproducible Detection of Proteins/Pepti... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing the development of targeted mass spectrometric assays (e.g. Multiple Reaction Monitoring) for proteins and peptides of primary interest to the type 1 diabetes research community (e.g. glucagon, somatostatin, C-peptide, insulin). The proposed assays should be highly reproducible, easily transferable to other laboratories, easy to multiplex, and validated in human plasma or serum.
MiamiOH OARS

Mechanisms of Alcohol Tolerance (R21/R33 Clinical Trial Not Allowed) - 0 views

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    The intent of this FOA is two-fold: (1) develop new hypotheses about key factors and pathways in sensitivity and tolerance to alcohol, and (2) develop a common framework of mechanisms underlying the development of tolerance and the progression to alcohol dependence. These objectives will be accomplished with a Phased Innovation (R21/R33) mechanism, in which secondary data analysis or pilot studies can occur during the R21 phase, and research testing the hypotheses can be expanded in the R33 phase.
MiamiOH OARS

Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical ... - 0 views

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    The Office of Research on Women's Health (ORWH) announces the availability of administrative supplements to support research highlighting the impact of sex/gender influences in human health and illness, including basic, preclinical, clinical, translational, and behavioral studies. Of special interest are studies relevant to understanding the significance of biological sex on cells and tissue explants; comparative studies of male and female tissues, organ systems and physiological systems; sex-based comparisons of pathophysiology, biomarkers, gene expression, clinical presentation and prevention and treatment of diseases. The most robust experimental designs include consideration of both sex and gender; therefore, applications proposing to investigate the influence of both sex and gender factors are highly encouraged. The proposed research must address at least one objective from Goals 1 through 3 of the NIH Strategic Plan for Women's Health Research.
MiamiOH OARS

Promoting Adolescent Health through School-Based HIV Prevention - 0 views

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    The Centers for Disease Control and Prevention (CDC) proposes to allocate funds to implement Notice of Funding Opportunity (NOFO) PS18-1807, “Promoting Adolescent Health through School-Based HIV/STD Prevention.” The project period will be 5 years, with a 12-month budget period and an anticipated award date of August 1, 2018. This NOFO will provide support for education agencies and NGOs to help school districts and schools develop and implement sustainable program activities to: 1) Reduce HIV infection and other STDs among adolescents; and 2) Reduce disparities in risk for HIV infection and other STD infection. Throughout the 5-year cooperative agreement, awardees will conduct activities demonstrated to improve the health of middle school and high school students by collection and use of quality surveillance data, the implementation of effective prevention practices, and demonstration and evaluation of innovative strategies within their jurisdictions.
MiamiOH OARS

Basic Research in Cancer Health Disparities (R01 Clinical Trials Not Allowed) - 0 views

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    This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants (R01) will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This FOA is also designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of basic research expertise in cancer health disparities research who can expand available resources and tools, such as biospecimens, patient derived models, and methods that are necessary to conduct basic research in cancer health disparities.
MiamiOH OARS

Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed) - 0 views

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    This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants (R01) will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This FOA is also designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of basic research expertise in cancer health disparities research who can expand available resources and tools, such as biospecimens, patient derived models, and methods that are necessary to conduct basic research in cancer health disparities.
MiamiOH OARS

Epigenetic Characterization and Observation - 0 views

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    The Epigenetic CHaracterization and Observation (ECHO) program will utilize an individual's epigenome to reveal their history of exposure to weapons of mass destruction (WMD) and WMD precursors. The program will build a field-deployable platform capable of using the epigenome to diagnose biothreat exposures and infections and support military forensics operations to counter-WMD proliferation.
MiamiOH OARS

Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adu... - 0 views

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    This Funding Opportunity Announcement encourages developmentally tailored research focused on adolescents and emerging adults as it relates to HIV prevention and treatment. Research is encouraged to incorporate recent advances in adolescent and young adult developmental research to optimize outcomes in HIV prevention and care research for this heterogeneous population. PA-FY-NNN uses the R01 grant mechanism, PA-FY-NNN uses the R21 mechanism, while PA-FY-NNN uses the R34 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism. Applicants with preliminary data and/or planning to include longitudinal analysis may wish to apply using the R01 mechanism. Applicants wanting to develop and pilot test an intervention may wish to apply using the R34 mechanism.
MiamiOH OARS

NHLBI Clinical Ancillary Studies (R01 - Clinical Trial Optional) - 0 views

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    This Funding Opportunity Announcement (FOA) seeks to accelerate the pace and expand the breadth of scientific research on the clinical course, prevention and treatment of diseases within NHLBI's mission by leveraging ongoing clinical research studies through ancillary studies. This FOA invites research project applications to conduct ancillary studies to clinical research studies, including clinical trials, prospective observational studies, and/or registries. Applications submitted to this FOA should propose to collect new information and/or biological samples from participants of the ongoing parent study, and should address new research questions that are beyond those specified in the approved protocol of the parent study and are within the scientific mission of the NHLBI. Applications submitted to this FOA should not be used to extend the duration of the parent study or to provide funds solely for parent study enrollment, capitation, or study performance.
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