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MiamiOH OARS

PA-18-784: The Mechanistic Role of the Microbiome in the Pathobiology of Heart, Lung, B... - 0 views

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    The purpose of this funding opportunity announcement (FOA) is to support functional microbiome research focused on understanding the molecular, immunological and physiological mechanisms by which the microbiota (gut, lung, oral, including bacteria, viral and fungal microflora) and its derived factors modulate heart, lung, blood and sleep (HLBS) biology and physiology to promote health or contribute to disease. This FOA encourages mechanistic studies using in vitro, in vivo and/or ex vivo models that focus on the mechanistic and functional involvement of the microbiome and their components in the modulation or activation of host pathways. The goal is to provide the critical knowledge to guide early translational approaches for better understanding and treatment of HLBS conditions in adults and children. This FOA encourages multidisciplinary collaborations among scientists in a wide range of disciplines including (but not limited to) cardiology, pulmonology, hematology, sleep science, circadian biology, immunology, '-omic' sciences, microbiology, microbial ecology, biotechnology, and bioinformatics.
MiamiOH OARS

Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K0... - 0 views

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    The purpose of the Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01) is to provide support and protected time (three, four, or five years) for an intensive, supervised career development experience in research in biomedical, behavioral, and social science research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing and that will lead to research independence.
MiamiOH OARS

Engineering of Biomedical Systems - 0 views

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    The Engineering of Biomedical Systems (EBMS)program is part of the Engineering Biology and Health cluster, which also includes 1) Biophotonics; 2) Biosensing; 3) Cellular and Biochemical Engineering; and 4) Disability and Rehabilitation Engineering. The goal of theEBMS program is to provide research opportunities for creating discovery-level and transformative projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term.EBMS projects must be at the interface of engineering and biomedical sciences. They are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. The project must include objectives that advance both engineering and biomedical sciences. EMBS projects should focus on high-impact, transformative methods and technologies -- especially those that potentially will have a broad impact on biomedical challenges. Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term. TheEBMS programsupports fundamental and transformative research in the following areas of biomedical engineering:
MiamiOH OARS

Biosensing - 0 views

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    ) multiplex biosensing platforms that exceed the performance of current state-of-the-art devices; 2) novel transduction principles, mechanisms and sensor designs suitable for measurement in practical matrix and sample-preparation-free approaches, including error-free detection of pathogens and toxins in food matrices, waterborne pathogens, parasites, toxins, biomarkers in body fluids, neuron chemicals, and others that improve human condition; 3) biosensors that enable measurement of biomolecular interactions in their native states, transmembrane transport, intracellular transport and reactions, and other biological phenomena; 4) biosensing performance optimization for specific health applications such as point-of-care testing and personalized health monitoring; and 5) miniaturization of biosensors for lab-on-a-chip and cell/organ-on-a-chip applications to enable measurement of biological properties and functions of cell/tissues in vitro. The Biosensors Program does not encourage proposals addressing surface functionalization and modulation of bio-recognition molecules, development of basic chemical mechanisms for biosensing applications, circuit design for signal processing and amplification, computational modeling, and microfluidics for sample separation and filtration.
MiamiOH OARS

Cellular and Biochemical Engineering - 0 views

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    The Cellular and Biochemical Engineering (CBE)program is part of the Engineering Biology and Health cluster, which also includes 1) Biophotonics; 2) Biosensing; 3) Disability and Rehabilitation Engineering; and 4) Engineering of Biomedical Systems. TheCellular and Biochemical Engineering program supports fundamental engineering research that advances understanding of cellular andbiomolecular processes in engineering biology. CBE-funded research eventually leads to the development of enabling technology for advanced biomanufacturing in support of the therapeutic cell, biochemical, biopharmaceutical, and biotechnology industries. Fundamental to many research projects in this area is the understanding of how biomolecules, subcellular systems, cells, and cell populations interact in the biomanufacturing environment, and how those interactions lead to changes in structure, function, and behavior. A quantitative treatment of problems related to biological processes is considered vital to successful research projects in the CBE program. The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches. The CBE program also encourages proposals that effectively integrate knowledge and practices from different disciplines while incorporating ongoing research into educational activities.
MiamiOH OARS

Molecular Separations - 0 views

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    The Molecular Separations program is part of the Chemical Process Systems cluster, which also includes 1) Catalysis; 2) Electrochemical Systems; and 3) Process Systems, Reaction Engineering, and Molecular Thermodynamics. The Molecular Separations program supports research focused on novel methods and materials for separation processes, such as those central to the chemical, biochemical, bioprocessing, materials, energy, and pharmaceutical industries. A fundamental understanding of the interfacial, transport, and thermodynamic behavior of multiphase chemical systems as well as quantitative descriptions of processing characteristics in the process-oriented industries is critical for efficient resource management and effective environmental protection. The program encourages proposals that address long standing challenges and emerging research areas and technologies, have a high degree of interdisciplinary work coupled with the generation of fundamental knowledge, and the integration of education and research. Research topics of particular interest include fundamental, molecular-level work.
MiamiOH OARS

Ending the Pandemic Threat: A Grand Challenge for Universal Influenza Vaccine Developme... - 0 views

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    The Bill & Melinda Gates Foundation has issued an Request for Proposals for research that will lead to the development of a universal influenza vaccine
    Part of the foundation's Grand Challenges program, the goal of the foundation's Ending the Pandemic Threat: A Grand Challenge for Universal Influenza Vaccine Development initiative is to identify novel, transformative concepts that will lead to development of universal influenza vaccines offering protection from morbidity and mortality caused by all subtypes of circulating and emerging (drifted and shifted) Influenza A subtype viruses and Influenza B lineage viruses for at least three to five years. It is envisaged that such a universal influenza vaccine would address the threat from both seasonal and pandemic influenza, thus alleviating the need for annual seasonal influenza vaccination campaigns, averting significant global morbidity and mortality, and better preparing the world for the next influenza pandemic.
    While other funders are supporting development of universal Influenza vaccines, three things set this Grand Challenge apart. The Gates Foundation seeks to fund ideas that are bold and innovative, bridging the funding 'valley of death' to translate these novel approaches into products ready for human clinical trials. It also aims to encourage interdisciplinary collaboration and cross-fertilization of ideas from outside the traditional influenza research community. Third, it seeks completely transformative approaches rather than incremental research.
MiamiOH OARS

Tuberous Sclerosis Complex Idea Development Award - 0 views

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    The Idea Development Award promotes ideas that have the potential to yield high-impact findings and new avenues of investigation. This award mechanism supports conceptually innovative research that could ultimately lead to critical discoveries in TSC research and/or improvements in patient care. Research projects should include a well-formulated, testable hypothesis based on strong preliminary data and scientific rationale.
MiamiOH OARS

RFA-CA-18-014: Investigation of the Transmission of Kaposi Sarcoma-Associated Herpesvir... - 0 views

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    The purpose of the funding opportunity announcement (FOA) is to advance our understanding of the modes of transmission of Kaposi sarcoma-associated herpesvirus (KSHV), also called human herpesvirus-8 (HHV-8); the biology of the initial steps of infection; and risk factors for infection to inform efforts to prevent KSHV transmission and thus prevent Kaposi sarcoma (KS), KSHV-associated multicentric Castleman disease (MCD), primary effusion lymphoma (PEL), and other KSHV-induced diseases in populations living with HIV or at high risk of developing HIV.
    This program covers two parallel FOAs of identical scientific scope. This FOA solicits applications for exploratory/developmental projects using the NIH R21 mechanism. The companion FOA, RFA-CA-18-013, is a parallel announcement for well-developed research projects using the NIH R01 funding mechanism.
MiamiOH OARS

NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed) - 0 views

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    The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NINDS R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs.
MiamiOH OARS

Enhance the National Department of Health's coordination and leadership on HIV and TB p... - 0 views

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    South Africa's has been making steady progress towards 90-90-90 targets, but these targets are unlikely to be attained without additional support and resources. The South African Department of Health developed an HIV Treatment and Retention Acceleration Plan (TRAP) in September 2017 to aggressively improve performance in the ART Program. CDC has been partnering with National Department of Health (NDoH) for several years through three consecutive cooperative agreements, 2003 to 2009, 2009 to 2014 and currently 2014 to 2019. This follow-on NOFO will allow CDC South Africa to continue to support and engage with the National Department of Health in developing and reviewing guidance and policy documents on HIV and TB, support surveys and surveillance activities to correctly characterize and describe the epidemic, provide guidance on evidence-based program implementation and coordinate monitoring and evaluation activities and other health systems interventions to assess effectiveness of interventions and program performance and ensure that health delivery systems are functional and structurally conducive to optimal HIV and TB service delivery.
MiamiOH OARS

PAR-18-782: NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed) - 0 views

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    The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NINDS R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral and clinical research needs.
    To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development and Research Experiences.
    The purpose of this funding opportunity announcement is to encourage applications for the initiation or continuation of nationally-available neuroscience research education programs that will significantly advance the mission of NINDS. The primary focus of programs submitted under this FOA should be on intensive hands-on experience that will provide research experience, an in depth understanding of techniques and analytic approaches and expertise that is only possible with a nationally-organized program. Within the context of gaining expertise primarily through hands-on experience, programs may include immersive coursework and expert discussion when appropriate. Programs appropriate for this FOA must include participants from a nationally recruited cohort, selected through an application process by a well-balanced leadership committee.
MiamiOH OARS

PAR-18-781: Collaborative Cross (CC) Mouse Model Generation and Discovery of Immunoregu... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to support the use of Collaborative Cross (CC) mouse lines to advance understanding of the host genetics involved in immune regulation and function and to further develop CC mouse lines that more faithfully reproduce human immune responses. Applicants may include CC, CC derivatives with reproducible genomes and/or CC-RIX mice to accomplish these goals. Research areas supported by this FOA include immune system development, function or regulation; mechanisms governing immune response to infectious pathogens, vaccines or adjuvants; host susceptibility factors and mechanisms of pathogen-induced immunopathology; and immune mechanisms involved in the development and progression of immune-mediated diseases, such as allergy/asthma, autoimmunity, primary immunodeficiency, inflammation, and cell/organ/tissue transplant rejection or tolerance.
MiamiOH OARS

PAR-18-777: Novel Genomic Technology Development (R01 Clinical Trial Not Allowed) - 0 views

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    This Funding Opportunity Announcement (FOA) seeks grant applications to catalyze major advances in genomics through technology development (beyond developing nucleic acid sequencing technologies). The goal is to provide a mechanism for support of very novel and high impact work from across this gamut of genomics technology development. This initiative seeks to support technologies that will have a major impact in the next five to seven years.
MiamiOH OARS

PA-18-780: Development and Testing of Novel Interventions to Improve HIV Prevention, Ca... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research. For the purposes of this FOA, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons who are HIV infected.
MiamiOH OARS

PA-18-775: Pilot and Feasibility Studies in Preparation for Drug and Alcohol Abuse Prev... - 0 views

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    This Funding Opportunity Announcement (FOA) for R34 applications seeks to support: (a) pilot and/or feasibility testing of innovative new, revised, or adapted prevention intervention approaches to prevent or delay the initiation and onset of drug and alcohol use, the progression to misuse or problem use or alcohol and other substance use disorder, reduce drinking and driving and deaths related to impaired driving, prevent suicide attempts (nonfatal and fatal), and the drug- or alcohol-related acquisition or transmission of HIV infection and viral hepatitis among diverse populations and settings; and, (b) pre-trial feasibility and acceptability testing for prevention services and systems research. It is expected that research conducted via this mechanism will consist of studies that are a pre-requisite for preparing and submitting subsequent applications for larger scale drug or alcohol abuse prevention and/or drug- or alcohol-related HIV prevention intervention studies. This FOA does not support applications for which the sole focus is development of intervention protocols, manuals, or the standardization of protocols. Any intervention development work must be imbedded within a pilot/feasibility study. Of particular interest is prevention research that addresses current public health priorities and priority settings and systems.
MiamiOH OARS

PA-18-773: International Research Collaboration on Drug Abuse and Addiction Research (R... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages collaborative research applications on drug abuse and addiction that:
    1. Take advantage of unusual opportunities that exist outside the United States to access talent, resources, populations, or environmental conditions in other countries that will speed scientific discovery
    2. Describe how the research will significantly advance U.S. health sciences
    3. Demonstrate specific relevance to the NIDA mission and objectives. To determine whether your research plan is relevant to the NIDA mission and objectives, review the NIDA Strategic Plan (https://www.drugabuse.gov/about-nida/2016-2020-nida-strategic-plan). Where feasible, applications should address NIDA's international scientific priority areas (https://www.drugabuse.gov/international/research-priorities)
    4. Include an investigator from a U.S. institution and a non-U.S. citizen partner living and working in another country.
MiamiOH OARS

American College of Psychiatrists Invites Nominations for Mood Disorder Award | RFPs | PND - 0 views

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    Founded in 1963, the St. Louis-based American College of Psychiatrists is a not-for-profit honorary association dedicated to providing continuing education to its members, promoting the latest advances in the field, and supporting the highest standards. To advance this mission, the college is seeking nominations for its Mood Disorders Awards.
    The annual award recognizes an individual who has advanced the understanding and treatment of mood disorders. The awardee receives a grant, certificate, travel and hotel expenses, and free registration at the ACP annual meeting.
    To be eligible, nominees must be a members of ACP in good standing.
MiamiOH OARS

Tick-Borne Disease, Career Development Award - 0 views

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    The FY18 TBDRP Career Development Award (CDA) supports independent, early-career
    investigators to conduct impactful research with the mentorship of an experienced tick-borne
    diseases researcher (i.e., the Mentor) as an opportunity to obtain the funding, guidance, and
    experience necessary for productive, independent careers at the forefront of tick-borne diseases
    research. This award supports impactful research projects with an emphasis on discovery.
    Under this award mechanism, the early-career investigator is considered the Principal Investigator
    (PI), and the application should focus on the PI's research and career development. It should be
    clear that the proposed research is intellectually designed by the PI and not a product of the
    Mentor. Preliminary data are not required. However, logical reasoning and a sound
    scientific rationale for the proposed research must be demonstrated.
MiamiOH OARS

Ferring Innovation Grants - Ferring Pharmaceuticals | Ferring Pharmaceuticals - 0 views

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    Ferring is committed to building a portfolio of novel, innovative drugs to address the indications of high unmet medical need for patients in our core therapeutic areas of interest.  

    The Ferring Innovation Grants are awarded annually in January and are not renewable.

    We will NOT fund clinical studies, or studies which require the collection of human samples under the direction of an Institutional Review Board.

    Proposals should only include analysis of anonymized human samples collected independently of this application.

    Therapeutic areas of interest to Ferring include:
    - Gastroenterology & Hepatology
    - Reproductive Medicine & Women's Health
    - Urology
    - Biomarker Discovery
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