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The purpose of this FOA is to invite applications that will seek to prospectively define and/or validate pulmonary or immune system attributes associated with pre-symptomatic disease states or resilience, with the goal of informing the development of primary prevention strategies for chronic lung diseases.

The purpose of this FOA is to invite applications that will seek to prospectively define and/or validate pulmonary or immune system attributes associated with pre-symptomatic disease states or resilience, with the goal of informing the development of primary prevention strategies for chronic lung diseases.

The purpose of this funding opportunity announcement is to encourage applications on biomarker discovery that utilize metabolomics approaches to advance the understanding, assessment and management of symptoms.

This FOA calls for exploratory/novel research projects on the basic behavioral, social and biopsychosocial (also called biobehavioral or biosocial) mechanisms that empower or impede a person's management of one or more chronic conditions.

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. 

The NPIs of interest will include at least one social distancing measure of interest, and an improved personal hygiene (hand washing and/or alcohol-based hand sanitizer use) and environmental hygiene practice (cleaning of frequently touched surfaces) within schools. T

The goals of this funding opportunity announcement are to support science that will ultimately help: 1) Improve the ability to identify who is at risk for sub-optimal weight loss, weight regain, and short- or long-term adverse metabolic/physiologic or behavioral outcomes based on behavioral or psychological characteristics and 2) Inform the development of new treatment approaches to be used pre and/or post-surgery to minimize risks and improve outcomes or allow for more tailored patient and procedure selection.

The purpose of this funding opportunity announcement (FOA) is to support the innovative biomedical and proof-of-concept research needed to understand how reproductive maturation or injury alters the mucosal environments at HIV susceptible sites. This information is essential to provide the safest and most efficacious biomedical prevention strategies (e.g., topical microbicides and Pre-Exposure Prophylaxis (PrEP), etc.) to those populations at heightened risk of HIV infection.  

The purpose of this Funding Opportunity Announcement (FOA) is to support research to identify and evaluate the basic underlying molecular and physiological mechanisms by which the virome may influence heart, lung, and blood (HLB) health and resilience.    

The purpose of this Funding Opportunity Announcement is to foster the advancement of the research mission of the Division of Digestive Diseases and Nutrition, NIDDK by soliciting research concepts that for pilot and feasibility clinical study proposals would need further assessment of identified protocol operational challenges would enhance operational feasibility of achieving successful completion of a subsequent larger clinical study; or for clinical translational science proposals, promote exploratory and novel science through the use of human subjects. The following studies will not be supported by this FOA: those that have obesity as a component of the study proposal (please refer to the Office of Extramural Research Grants and Funding to search for multiple obesity related Funding Opportunity Announcements at https://grants.nih.gov/grants/oer.htm); and translational studies that utilize animal models.

The purpose of this FOA is to support a more efficient method for jurisdictions to de-duplicate the National HIV Surveillance System. The applicant will develop a privacy data-sharing tool capable of identifying potential duplicates across jurisdictions. Activities will include acquiring a Security Assessment and Authorization, negotiating with the 59 jurisdictions to obtain their participation, providing a data sharing tool that will allow for secure, encrypted submission and matching of person-level HIV surveillance data, and providing a report back to jurisdictions on matching levels.

Computational neuroscience provides a theoretical foundation and a rich set of technical approaches for understanding complex neurobiological systems, building on the theory, methods, and findings of computer science, neuroscience, and numerous other disciplines. Through the CRCNS program, the National Science Foundation (NSF), the National Institutes of Health (NIH), the German Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung, BMBF), the French National Research Agency (Agence Nationale de la Recherche, ANR), the United States-Israel Binational Science Foundation (BSF), and Japan's National Institute of Information and Communications Technology (NICT) support collaborative activities that will advance the understanding of nervous system structure and function, mechanisms underlying nervous system disorders, and computational strategies used by the nervous system.

 The purpose of this project is to identify skin physiology characteristics that differ between healthy and skin disease population groups and incorporate them into dermal physiologically-based pharmacokinetic models to improve their predictability. The models developed will be utilized to perform virtual bioequivalence assessments between brand name and generic drug products to inform regulatory decisions relating to the development of generic topical dermatological drug products and transdermal delivery systems.       

This Funding Opportunity Announcement (FOA) solicits research grant applications which will: 1) advance measurements of intersectional stigma (multiple stigmatized identities) and examine the mechanisms and pathways by which it is a barrier to HIV testing and linkage to prevention; or 2) develop and test interventions to reduce intersectional stigma and improve the uptake of HIV testing and linkage to ongoing HIV prevention among key populations at substantial risk for HIV infection.

This Funding Opportunity Announcement (FOA) solicits research grant applications which will: 1) advance measurements of intersectional stigma (multiple stigmatized identities) and examine the mechanisms and pathways by which it is a barrier to HIV testing and linkage to prevention; or 2) develop and test interventions to reduce intersectional stigma and improve the uptake of HIV testing and linkage to ongoing HIV prevention among key populations at substantial risk for HIV infection. RFA-MH-19-412 uses the R01 grant mechanism, and RFA-MH-19-410 uses the R34 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism. Applicants with preliminary data and/or include longitudinal analysis may be appropriate for the R01 mechanism. Applicants proposing to develop and pilot test an intervention should consider using the R34 mechanism.

This Funding Opportunity Announcement (FOA) solicits research grant applications which will: 1) advance measurements of intersectional stigma (multiple stigmatized identities) and examine the mechanisms and pathways by which it is a barrier to HIV testing and linkage to prevention; or 2) develop and test interventions to reduce intersectional stigma and improve the uptake of HIV testing and linkage to ongoing HIV prevention among key populations at substantial risk for HIV infection.

The U.S. Army Medical Research and Materiel Command's mission is to responsively and responsibly create, develop, deliver, and sustain medical capabilities for the Warfighter. The AIMM initiative was created to accelerate transformational biomedical research for our Armed Forces and Nation. The mission of the AIMM initiative is to encourage, identify, and enable innovative research that leads to cross-cutting solutions to military health threats. The AIMM Research Award is intended to support highly creative and conceptually innovative high-risk research with the potential to accelerate critical discoveries or major advancements that will significantly impact military health and medicine. AIMM initiative funding supports novel research concepts and other efforts that initiate or enhance potential game-changers that may not be supported by other funding mechanisms or core programs.

The purpose of the administrative supplement is to provide support for NIH-funded investigators to prepare and deposit individual-level data from cancer epidemiology studies into NIH/NCI-supported, controlled-access databases including the Cancer Epidemiology Data Repository (CEDR) and the database of Genotypes and Phenotypes (dbGaP). Sharing of research data will accelerate scientific discovery and increase opportunities for collaboration to provide new clues to cancer etiology, determine risk factors, and improve cancer survivorship.

The National Institute of General Medical Sciences (NIGMS) announces the availability of funds for Administrative Supplements to NIGMS-funded predoctoral T32 training grants. These funds are designed to provide support for the development and implementation of curricular or training activities aimed at the development of the technical, operational, or professional skills to become a biomedical scientist. The funds are designed to promote the reworking and revitalization of biomedical predoctoral research education and training.

The National Institute of General Medical Sciences (NIGMS) announces the availability of funds for Administrative Supplements to NIGMS-funded predoctoral T32 training grants. These funds are designed to provide support for the development and implementation of curricular or training activities aimed at providing trainees with the knowledge and skills to enhance laboratory safety. The funds are designed to promote the reworking and revitalization of biomedical predoctoral research education and training.