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MiamiOH OARS

PA-18-757: Administrative Supplements to NIGMS Predoctoral Training Grants for the Deve... - 0 views

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    The National Institute of General Medical Sciences (NIGMS) announces the availability of funds for Administrative Supplements to NIGMS-funded predoctoral T32 training grants. These funds are designed to provide support for the development and implementation of activities aimed at broadening the training experience to better prepare individuals for careers in the biomedical research workforce.
MiamiOH OARS

RFA-FD-18-020: Three-Dimensional Approach for Modeling Nasal Mucociliary Clearance via ... - 0 views

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    FDA's CDER is seeking a computational modeling approach to study the effects of mucociliary clearance on localized drug absorption in the nasal cavity. The modeling approach would utilize computational fluid dynamics (CFD) simulations of inhalation and droplet/particle transport to provide regional nasal spray deposition data, while the three-dimensional mucociliary clearance model would demonstrate localized drug absorption and indicate the efficacy of drug products that target specific nasal regions. The model should be adaptable to cases of interindividual variability, which may include variations in mucociliary clearance rates, changes in nasal geometry, and the presence of relevant disease states (e.g., nasal inflammation, changes in mucus properties, etc.).

MiamiOH OARS

Apply for a Grant from The Michael J. Fox Foundation | Parkinson's Disease - 0 views

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    The Michael J. Fox Foundation will award one-to-two-year grants to test non-pharmacological interventions for the treatment of gait and balance disturbances in people with Parkinson's disease (PD). We are particularly interested in proof-of-concept, validation and data-analysis projects.



    This program seeks proposals for research studying the therapeutic benefit of:
    Assistive devices (e.g., back or leg braces).
    Novel technologies (e.g., laser or wearable devices).
    Rehabilitative therapy programs (e.g., occupational or physical therapy)
MiamiOH OARS

Request for Applications | The Chan Zuckerberg Initiative - 0 views

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    These are three-year grants for small group interdisciplinary collaborations. At least one member of the collaboration should be a physician with active clinical engagement in an area relevant to the proposal. These grants are aimed to support innovative, bold, high risk/high impact projects at the interface of basic and disease biology. The scope of these collaborations should focus on foundational science (as opposed to translation and clinical application), aligned with clinical context.
MiamiOH OARS

RFA-FD-18-017: Characterize skin physiology parameters utilized in dermal physiological... - 0 views

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     The purpose of this project is to identify skin physiology characteristics that differ between healthy and skin disease population groups and incorporate them into dermal physiologically-based pharmacokinetic models to improve their predictability. The models developed will be utilized to perform virtual bioequivalence assessments between brand name and generic drug products to inform regulatory decisions relating to the development of generic topical dermatological drug products and transdermal delivery systems.       

MiamiOH OARS

Internships in Biomedical Informatics - 0 views

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    The Department of Biomedical Informatics hosts an annual internship program each summer which provides high school, undergraduate, and graduate students opportunities to pursue research projects in the field of biomedical informatics under the guidance of research and operational staff and renowned faculty mentors in the Department of Biomedical Informatics. Participants learn useful tools and technologies used in biomedical and clinical research and attend weekly seminars to learn more about the various fields and interdisciplinary interactions biomedical informatics facilitates. Interns also gain very useful presentation abilities through regular lab and programmatic presentation opportunities, including an end-of-program poster session.

    Many students who have participated in this program have gone on to pursue doctoral degrees in biomedicine, biomedical informatics, computer science, and electrical engineering or to complete degrees in medicine and nursing.

    All student internship positions in the Department of Biomedical Informatics have the potential to be either paid or unpaid, depending on student experience levels and faculty preference. Most positions have the ability to turn into full student employment opportunities, and/or count for course credit (depending on performance) during the school year.
MiamiOH OARS

Training Modules to Enhance the Rigor and Reproducibility of Biomedical Research (R25 C... - 0 views

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    The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral and clinical research needs.

    To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on developing courses for skills development - specifically, exportable training modules designed to enhance the rigor and reproducibility of biomedical research, targeted to trainees and researchers at any level.
MiamiOH OARS

RFA-RM-18-012: Rodent Testing Centers for Development of Reporter Systems and Evaluatio... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to create rodent reporter models for testing in vivo genome editing technologies, and to use these animal models to test genome editing delivery technologies and new genome editors developed under RFA-RM-18-016 and RFA-RM-18-017. The deliverables from the initiative will be a set of animal models (mice and rat), containing one or more reporter genes expressed in all cell types, that will allow facile and quantitative evaluation of genome editing in any cell type of interest. The Testing Centers will use these models to validate new delivery systems and genome editing tools developed by other investigators in the Somatic Cell Genome Editing program.  The creation and testing of these rodent models will accelerate the translation of genome editing technologies into treatments for human diseases. 

MiamiOH OARS

AIDS United | Evidence-Informed Interventions RFP - 0 views

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    AIDS United, in collaboration with the Health Resources and Services Administration's HIV/AIDS Bureau and The Fenway Institute, is offering funding through the Using Evidence-Informed Interventions to Improve Health Outcomes among People Living with HIV initiative. The goal of this initiative is to support the implementation of evidence-informed interventions to reduce HIV-related health disparities and improve health outcomes, including increasing retention in care, improving treatment adherence, and improving viral suppression for people living with HIV. Up to 24 intervention sites will receive $170,000 per year to support the development and implementation of interventions. Ryan White HIV/AIDS Program recipients or subrecipients that operate within the United States or its territories are eligible to apply. Proposals must be submitted by January 22, 2018. Visit the AIDS United website to download the RFP.
MiamiOH OARS

PSC Partners Seeking a Cure - 0 views

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    Support to patients with primary sclerosing cholangitis, an autoimmune disease that causes the bile ducts inside and outside the liver to become scarred, narrowed, and eventually blocked, as well as their families and caregivers, and to raise funds for research on the causes, treatments, and a cure for PSC.

    To that end, the foundation offers grants of up to $60,000 over two years tor research projects that address an important and novel, basic, or clinical research question related to PSC and closely allied diseases (such as inflammatory bowel diseases, ulcerative colitis, or Crohn's disease).
MiamiOH OARS

PAR-18-528: NeuroNEXT Clinical Trials (U01 - Clinical Trial Optional) - 0 views

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    This FOA encourages applications for exploratory clinical trials of investigational agents (drugs, biologics, surgical therapies or devices) that may contribute to the justification for and provide the data required for designing a future trial, for biomarker validation studies, or for proof of mechanism clinical studies. Diseases chosen for study should be based on the NINDS' strategic plan and clinical research interests (www.ninds.nih.gov/funding/areas/index.htm). Successful applicants will be given access to the NeuroNEXT infrastructure. Following peer review, NINDS will prioritize and order trials that are given access to the NeuroNEXT infrastructure. The NeuroNEXT Clinical Coordinating Center (CCC) will work with the successful applicant to efficiently implement the proposed study. The NeuroNEXT Data Coordinating Center (DCC) will provide statistical and data management support. The NeuroNEXT clinical sites will provide recruitment/retention support as well as on-site implementation of the clinical protocol.
MiamiOH OARS

PAR-18-266: Centers of Biomedical Research Excellence (COBRE) (P20 Clinical Trial Optio... - 0 views

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    The National Institute of General Medical Sciences (NIGMS) invites applications for Centers of Biomedical Research Excellence (COBRE) from investigators at biomedical research institutions that award doctoral degrees in the health sciences or sciences related to health or at independent biomedical research institutes with ongoing biomedical research programs funded by the NIH or other federal agencies within Institutional Development Award (IDeA) eligible states. The objectives of the COBRE initiative is to strengthen an institution's biomedical research infrastructure through the establishment of a thematic multi-disciplinary center and to enhance the ability of investigators to compete independently for complementary National Institutes of Health (NIH) individual research grants or other external peer-reviewed support. COBRE awards are supported through the IDeA Program, which aims to foster health-related research by increasing the competitiveness of investigators at institutions located in states with historically low aggregate success rates for grant awards from the NIH.
MiamiOH OARS

PAR-18-264: Limited Competition: Renewal of Centers of Biomedical Research Excellence (... - 0 views

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    The National Institute of General Medical Sciences (NIGMS) of the NIH invites applications for renewal of eligible Centers of Biomedical Research Excellence (COBRE) grants. The objective of the COBRE initiative is to strengthen an institution's biomedical research infrastructure through the establishment of a thematic, multi-disciplinary center and to enhance the ability of investigators to compete independently for National Institutes of Health (NIH) individual research grants or other external peer-reviewed support. COBRE awards are supported through the Institutional Development Award (IDeA) Program, which aims to foster health-related research by increasing the competitiveness of investigators at institutions located in IDeA states.
MiamiOH OARS

PAR-18-263: Limited Competition: Centers of Biomedical Research Excellence (COBRE) Phas... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to transition the core resources and biomedical research activities of Centers of Biomedical Research Excellence (COBRE) into independence and sustainability.
MiamiOH OARS

RFA-ES-18-005: The Role of the Microbiome in the Developmental Origins of Health and Di... - 0 views

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    This Funding Opportunity Announcement (FOA) seeks innovative research proposals that use animal models to investigate the potential role of the microbiome in mediating the latent effects of early life exposure.
MiamiOH OARS

PAR-18-413: Mechanistic Basis of Diffuse White Matter Disease and Small Vessel Patholog... - 0 views

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    The purpose of this funding opportunity announcement (FOA) is to support hypothesis-testing research to elucidate cellular and molecular mechanisms that underlie diffuse white matter disease and small vessel disease in the brain, the relationships between them, and how they may contribute to cognitive impairment and dementia.
MiamiOH OARS

PA-18-072: AIDS-Science Track Award for Research Transition (R03 Clinical Trial Optional) - 0 views

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    This funding opportunity announcement (FOA) seeks to facilitate the entry of both newly independent and early career investigators to the area of drug abuse research on HIV/AIDS. This FOA, AIDS-Science Track Award for Research Transition (A-START), encourages Small Research Grant (R03) applications to support research projects on drug abuse and HIV/AIDS that can be carried out in a short period of time with limited resources. Applications under this FOA are welcomed from all areas of HIV/AIDS research that NIDA supports.
MiamiOH OARS

PAR-18-103: Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (... - 0 views

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    The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) announces a program that provides NIDDK-supported K01, K08, and K23 recipients the opportunity to apply for Small Grant (R03) support at some point during the final two years of their K award. Through the use of this mechanism, the NIDDK is seeking to enhance the capability of its K01, K08, and K23 award recipients to conduct research as they complete their transition to fully independent investigator status. The R03 grant mechanism supports different types of projects, including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that may provide preliminary data to support a subsequent R01, or equivalent, application.
MiamiOH OARS

Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21 Clinical Trial O... - 0 views

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    This Funding Opportunity Announcement (FOA) is to support Exploratory/Developmental Research Grants (R21) that propose small scale or pilot and feasibility clinical and translational research studies, including epidemiological studies or clinical trials related to kidney disease research. Studies should address important clinical and translational questions and are potentially of high clinical and public health impact. It is anticipated that some projects supported by these grants may lead to full-scale clinical studies including diagnostic strategies, epidemiological studies, or randomized clinical trials of diagnosis, prevention, or treatment of kidney diseases.
MiamiOH OARS

Notice of Funding Opportunity Publication for Biomedical Data Translator: Technical Fea... - 0 views

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    NCATS plans to support the research, development and testing of up to three biomedical reasoning tool prototypes for the Biomedical Data Translator for an estimated $1,000,000 total costs each. NCATS is utilizing a three-step application process (challenge-concept-proposal) for this expedited program. The duration of each award will be less than one year. All awardees will be expected to collaborate and cooperate with NCATS staff, one another and potentially other contributors to the overall program to maximize the exploration of the potential capabilities of Translator and to understand technical feasibility and challenges of having multiple groups build a single resource.
    All U.S. and foreign organizations and U.S. citizens are eligible to apply. This funding opportunity is open to U.S. and foreign organizations, including academic institutions and commercial entities; subcontracts are allowed. U.S. citizens may also apply as individuals and may be direct recipients of an award. Non-citizen individuals residing in the U.S. or foreign country not affiliated with either a U.S. or foreign organization are not eligible to be direct recipients of an award.
    Successful completion of the application process will require applicants to have specific skills related to translational research and software development. Applicants need to demonstrate technical skills, including familiarity with web communication protocols, a variety of programming languages and software stack, and general algorithmic techniques in the areas of artificial intelligence, machine learning, and knowledge engineering, as well as problem solving skills, especially creativity and persistence. Applicants familiar with languages and packages most useful for solving different tasks, the entire challenge process may take between 2 and 8 hours to complete.
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