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"Cancer diagnosis and management depend upon the extraction of complex information from microscopy images by pathologists, which requires time-consuming expert interpretation prone to human bias. Supervised deep learning approaches have proven powerful, but are inherently limited by the cost and quality of annotations used for training. Therefore, we present Histomorphological Phenotype Learning, a self-supervised methodology requiring no labels and operating via the automatic discovery of discriminatory features in image tiles. Tiles are grouped into morphologically similar clusters which constitute an atlas of histomorphological phenotypes (HP-Atlas), revealing trajectories from benign to malignant tissue via inflammatory and reactive phenotypes. These clusters have distinct features which can be identified using orthogonal methods, linking histologic, molecular and clinical phenotypes. Applied to lung cancer, we show that they align closely with patient survival, with histopathologically recognised tumor types and growth patterns, and with transcriptomic measures of immunophenotype. These properties are maintained in a multi-cancer study."

""Quantum processors are peeling away at a double exponential rate and will continue to vastly outperform classical computers as we scale up," said Hartmut Neven, the founder of the firm, who said that the latest test results, published on Monday in Nature magazine, "cracks a key challenge in quantum error correction that the field has pursued for almost 30 years". He said the far greater speed of the new chip than classical computers "lends credence to the notion that quantum computation occurs in many parallel universes, in line with the idea that we live in a multiverse". Simply put, if a quantum computer can be in many different states at once, it can get more done at the same time."

"Meet the Tokyo candidate for governor who live-streamed for 17 days straight, answering 8,600 questions from potential voters. How? Enter 'AI Takahiro', an avatar created by 33-year old candidate Anno Takahiro. The avatar's livestream on YouTube was just one part of this former software engineer-turned-science-fiction writer's ground-breaking campaign, born out of frustration with the one-sided nature of political communication."

Humans process thoughts at just 10 bits per second, according to a recent paper published by Caltech researchers. In contrast, a human's sensory organs gather data at a billion bits per second. So, if you ever feel overwhelmed by what is going on around you, it's only natural. The research paper, dubbed 'The unbearable slowness of being: Why do we live at 10 bits/s?' ponders the human neural substrate which limits thoughts to such a slow pace, and proposes new research to look into this 'bottleneck' now that it has been quantified.

"While the Trump administration's scrubbing of federal web pages presents a notable example of the severed links issue, it's long been an epidemic. A Pew Research Center study published last year found that roughly 38% of web pages on the internet that existed in 2013 were no longer accessible as of 2023. According to a Harvard Law Review study published in 2014, about half of all links cited in U.S. Supreme Court opinions no longer led to the original source material. Kahle, who early on recognized the ephemeral nature of the web, said the rapid deterioration of the living web is a serious threat to historical preservation. "We're building our culture on shifting sands," he said."

"Big data and artificial intelligence are some of today's most popular buzzwords. Both are promised to help deliver insights that were previously too complex for computer systems to calculate. With examples ranging from personalised recommendation systems to automatic facial analyses, user-generated data is now analysed by algorithms to identify patterns and predict outcomes. And the common view is that these developments will have a positive impact on society."

"But, as he and other modellers warn, much information about how SARS-CoV-2 spreads is still unknown and must be estimated or assumed - and that limits the precision of forecasts. An earlier version of the Imperial model, for instance, estimated that SARS-CoV-2 would be about as severe as influenza in necessitating the hospitalization of those infected. That turned out to be incorrect."

"When the field of AI believes it is neutral, it both fails to notice biased data and builds systems that sanctify the status quo and advance the interests of the powerful. What is needed is a field that exposes and critiques systems that concentrate power, while co-creating new systems with impacted communities: AI by and for the people."

"Machines, it would seem, are about to get an awful lot chattier. And we've got our work cut out for us to make sure the conversation's meaningful."

"Most people who use AI-powered translation tools do so for commonplace, relatively unimportant tasks like understanding a single phrase or quote. Those basic services won't do for an enterprise offering technical documents in 15 languages - but Lengoo's custom machine translation models might just do the trick. And with a new $20 million B round, they may be able to build a considerable lead. The translation business is a big one, in the billions, and isn't going anywhere. It's simply too common a task to need to release a document, piece of software or live website in multiple languages - perhaps dozens."

"These experiments in computational creativity are enabled by the dramatic advances in deep learning over the past decade. Deep learning has several key advantages for creative pursuits. For starters, it's extremely flexible, and it's relatively easy to train deep-learning systems (which we call models) to take on a wide variety of tasks."

"Dan Gillmor, a journalism professor at Arizona State University, asked the AI to handle one of the assignments he gives his students: writing a letter to a relative giving advice regarding online security and privacy. "If you're unsure about the legitimacy of a website or email, you can do a quick search to see if others have reported it as being a scam," the AI advised in part. "I would have given this a good grade," Gillmor said. "Academia has some very serious issues to confront.""

"Journal editors, researchers and publishers are now debating the place of such AI tools in the published literature, and whether it's appropriate to cite the bot as an author. Publishers are racing to create policies for the chatbot, which was released as a free-to-use tool in November by tech company OpenAI in San Francisco, California."

"The intriguing echo of Eliza in thinking about ChatGPT is that people regard it as magical even though they know how it works - as a "stochastic parrot" (in the words of Timnit Gebru, a well-known researcher) or as a machine for "hi-tech plagiarism" (Noam Chomsky). But actually we do not know the half of it yet - not the CO2 emissions incurred in training its underlying language model or the carbon footprint of all those delighted interactions people are having with it. Or, pace Chomsky, that the technology only exists because of its unauthorised appropriation of the creative work of millions of people that just happened to be lying around on the web? What's the business model behind these tools? And so on. Answer: we don't know."

"No surprise, then, that Twitter is aglow with engineers and academics mocking Lemoine for falling into the seductive emptiness of his own creation. But while I agree that Lemoine has made a mistake, I don't think he deserves our scorn. His error is a good mistake, the kind of mistake we should want AI scientists to make."

"ne YouTuber, Dan Duffy, joined the search just to post a video of himself joining it, and was fined on a public order offence, which he also filmed. One TikTok account, Curtis Cool Stuff, posted a video of a man digging up woodland, and another of him roaming around a derelict house opposite the bank where Bulley was last seen. Another group of men had to be dispersed from the house, having travelled there from Liverpool."

"I have been working with generative AI and, even though I have been warning that these tools are improving rapidly, I did not expect them to really be improving that rapidly. On every dimension, Bing's AI, which does not actually represent a technological leap over ChatGPT, far outpaces the earlier AI - which is less than three months old! There are many larger, more capable models on their way in the coming months, and we are not really ready."

"ChatGPT Heralds an Intellectual Revolution Generative artificial intelligence presents a philosophical and practical challenge on a scale not experienced since the start of the Enlightenment."

"But for many scientists, Twitter has become an essential tool for collaboration and discovery - a source of real-time conversations around research papers, conference talks and wider topics in academia. Papers now zip around scientific communities faster thanks to Twitter, says Johann Unger, a linguist at Lancaster University, UK, who notes that extra information is also shared in direct private messages through the site. And its limit on tweet length - currently 280 characters - has pushed academics into keeping their commentary pithy, he adds."