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Study sponsored by Imperial College London - Hypothesis: Study aims to determine whether whole body cooling to 33-34°C is a safe treatment that improves survival, without severe neurological or neurodevelopmental impairments at 18 months, of term infants suffering perinatal asphyxial encephalopathy

NICHD program focuses on developing research that links PCCR medicine and science to the epidemiology, prevention, and treatment of childhood disabilities. The effort sponsors competitive research on all aspects of PCCR-including critical analyses of outcomes for children who are survivors of trauma, congenital anomalies, neonatal asphyxia, infectious processes, septic shock, and many other less common, but still devastating hildhood processes. The PCCR program also provides support for the Pediatric Critical Care Scientist Development Program (PCCSDP) , a national faculty training and career development program that develops successful pediatric critical care physician scientists conducting research to enhance the scientific understanding, clinical management, and rehabilitation of pediatric critical illness.

Italian sponsored and NIH PubMed published abstract of study in the role of foetal lactate in the prevention of cerebral palsy during labor

PubMed Study Abstract: Vasoparalysis associated with brain damage in asphyxiated term infants - Dept of Neonatalogy, Rigshospitalet, Copenhagaon, Denmark, 1990

Study to determine the potential benefits of a home stimulation program to treat infants who have suffered from brain asphyxiation (lack of oxygen).

Study is to determine whether nerve growth factor (cerebrolysin®) therapy will improve the psychomotor outcome in infants with moderate and severe hypoxic ischemic encephalopathy.

Study to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.