Imperial College London sponsored trial in newborn infants with perinatal asphyxial encephalopathy assessing whether a combination of hypothermia and inhaled xenon preserve cerebral metabolism and structure.
Multicenter, randomized, controlled trial to compare the anti-seizure effect of parenteral MgSO4 versus oral labetalol in hypertensive pregnant women who are eligible for MgSO4 therapy. The primary outcome measure is eclampsia, and the secondary outcome measures include blood pressure control, and relevant antenatal, intrapartum, and postnatal maternal and fetal/neonatal parameters including adverse effects and complications.
Ongoing study sponsored by the University of Texas Health Science Center, Houston to evaluate the efficacy of fundoplication in premature infants with GERD and BPD.
This study is an observational study to prove that a new device, which measures the force of delivering a baby, (US patent 6,684,165) functions as described in the patent. This is the first time this has been used with patients. The device measures the force (pounds/kilograms) that is exerted as a doctor/midwife pulls on a baby during the delivery
Study to assess the development and neurological status of all children who were diagnosed as "mild ventriculomegaly" during the pregnancy in the last 6 years and to prospectively follow up all the children who will be diagnosed from the beginning of the study on for 6 years.
Proposed study is to improve the efficacy of BWSTT in children with cerebral palsy (CP) using a novel robotic therapy that applies controlled force to the leg during the swing phase of gait.
Study sponsored by NINDS to examine whether continuous use of transcranial direct current stimulation (tDCS) in combination with motor training can lead to long-term improvement in movement performance beyond what can be achieved with motor training alone.
Completed study comparing the blood drug levels of two prescribed medications, Immediate-release omeprazole 40 mg powder and delayed-release omeprazole 40 mg capsule to determine which drug is better absorbed in patients with a slow stomach emptying (gastroparesis). Delayed-release omeprazole has a protective coating to prevent the drug omeprazole from being neutralized by stomach acid. Immediate-release omeprazole has sodium bicarbonate (antacid) which neutralizes the stomach acid, eliminating the need for a protective coating. Immediate-release omeprazole suspension may have a more rapid pharmacokinetic profile and greater overall drug absorption in gastroparesis.
Future planned study with the objective of evaluating the relative merits, safety and effectiveness of the tailored TIF2 procedure in treating GERD patients who have persistent GERD symptoms despite PPI therapy.The secondary objective of the study is to evaluate the effectiveness of the tailored TIF procedure in restoring the antireflux barrier and eliminating gastroesophageal reflux.
Planned study is to determine if a weekly dose of Progesterone (17OHP) given to women with preterm rupture of the membranes will: 1.increase the probability of continuing the pregnancy until a favorable gestational age. 2.increase the interval between randomization and delivery.3.decrease neonatal morbidity.
Study is to obtain preliminary information about the efficacy and potential adverse effects of platelet concentrate injections in patients undergoing arthroscopic Sub-acromial Decompression (SD), arthroscopic Acromio-Clavicular (AC) joint resection, and arthroscopic Rotator Cuff (RC) repair. Investigators wish to determine whether the PRP shows efficacy in healing and learn of possible side-effects
Study sponsored by the university of Chicago to demonstrate the efficacy and safety of Vanquix for the management of acute repetitive seizures (ARS). Study will provide clinical evidence for the effective and safe use of a diazepam auto-injector, Vanquix, to provide patients and their caregivers with an alternative to rectal administration.
Study to determine if Inhaled Nitric Oxide (iNO) given into an oxygen hood is effective in improving oxygenation in term and near-term infants who have poor oxygenation but who are not yet mechanically ventilated.
Citicoline Brain Injury Treatment (COBRIT) trial of the effects of 90 days of citicoline on functional outcome in patients with complicated mild, moderate and severe traumatic brain injury. Citicoline (also known as CDP-Choline) is a naturally occurring endogenous compound. Citicoline may have neuroprotective effects and may potentiate neuro-recovery which has led to the evaluation of it as treatment for both stroke and TBI in animal models and in human clinical trials.
Completed study which compared the effectiveness of silver nitrate drops, erythromycin ointment, or no medication in preventing neonatal conjunctivitis caused by Chlamydia trachomatis and other eye infections. Additionally study compared side effects of the two prophylactic agents.
Abnormal Executive function (EF) profile was considered a major characteristic of Attention deficit / hyperactivity disorder (ADHD) and autism, and is frequently implicated in Developmental coordination disorder (DCD) children as well. This study is to characterize the profile of executive functions and eye movements in several populations of children with developmental disabilities.
The Fetal Hope Foundation's mission is to provide support, provide information, fund research, increase awareness and be an outlet for leading medical information pertaining to fetal distresses and syndromes. We are all about arming families and healthcare providers with information and helping to save babies' lives
The relation between eye movement and brain function is a subject of interest to the National Eye Institute. By comparing eye movement in healthy volunteers to research conducted on patients who have difficulty moving their eyes, the National Eye Institute hopes to develop and improve diagnostic procedures for people with eye diseases. Objectives: To study eye movement in 100 healthy adult and child volunteers. To understand how individuals see visual patterns and how eye movement affects the ability to see.
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