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Lee Vander Loop

Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal ... - 0 views

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    Imperial College London sponsored trial in newborn infants with perinatal asphyxial encephalopathy assessing whether a combination of hypothermia and inhaled xenon preserve cerebral metabolism and structure.
Lee Vander Loop

NEJM -- Moderate Hypothermia to Treat Perinatal Asphyxial Encephalopathy - 0 views

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    New England Journal of Medicine abstract of study to evaluate the effects of induction of moderate hypothermia in infants who had perinatal asphyxia. Study concluded that Induction of moderate hypothermia for 72 hours in infants who had perinatal asphyxia did not significantly reduce the combined rate of death or severe disability but resulted in improved neurologic outcomes in survivors. (Current Controlled Trials number, ISRCTN89547571 [controlled-trials.com] .)
Lee Vander Loop

TOBY: a Study of Treatment for Perinatal Asphyxia - 3 views

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    Study sponsored by Imperial College London - Hypothesis: Study aims to determine whether whole body cooling to 33-34°C is a safe treatment that improves survival, without severe neurological or neurodevelopmental impairments at 18 months, of term infants suffering perinatal asphyxial encephalopathy
Lee Vander Loop

Diagnosis of severe birth asphyxia and early predi... [J Perinat Med. 1994] - PubMed re... - 0 views

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    PubMed Study Abstract: Ten indicators available during the first two hours of life, such as clinical criteria of neonatal distress and postnatal arterial blood gases, were compared with the neonatal neurological course in sixty full term newborns with significant birth asphyxia in order to test their value for the diagnosis and the short-term prognosis of severe birth asphyxia. Birth asphyxia was defined as severe when it was followed by symptoms of moderate or severe post-asphyxial encephalopathy.
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