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Lee Vander Loop

Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis - 0 views

www.clinicaltrials.gov/...NCT00492622

clinical trials clinical trial drug study sodium bicarbonate gastroesophageal relux study research omeprazole GERD reflux

shared by Lee Vander Loop on 16 May 10 - Cached
  • Lee Vander Loop on 16 May 10
     
    Completed study comparing the blood drug levels of two prescribed medications, Immediate-release omeprazole 40 mg powder and delayed-release omeprazole 40 mg capsule to determine which drug is better absorbed in patients with a slow stomach emptying (gastroparesis). Delayed-release omeprazole has a protective coating to prevent the drug omeprazole from being neutralized by stomach acid. Immediate-release omeprazole has sodium bicarbonate (antacid) which neutralizes the stomach acid, eliminating the need for a protective coating. Immediate-release omeprazole suspension may have a more rapid pharmacokinetic profile and greater overall drug absorption in gastroparesis.
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