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Researchers devise technique to allow X-ray crystallography of un-crystallized molecule... - 0 views

phys.org/...-un-crystallized-molecule.html
shared by Elijah Velasquez on 03 Apr 13 - No Cached
  • Elijah Velasquez on 03 Apr 13
     
    If this was around during the discovery of antibody structure we might not have Fc and Fab regions!
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How antibodies neutralize mosquito-borne virus - 1 views

www.sciencedaily.com/...130402125044.htm virus antibodies
shared by Tyrell Varner on 02 Apr 13 - No Cached
  • The findings show the precise structure of the virus-like particle bound to a key part of the antibodies, called the antigen binding fragment, or Fab, which attaches to the heterodimers making up the virus's outer shell. The analyses showed that the antibodies stabilize the viral surface, hindering fusion to the host cell and likely neutralizing infection.
  • "This is the first time the structure of an alphavirus has been examined in this detail,"
  • Tyrell Varner on 02 Apr 13
     
    This could help researchers find a vaccine for this disease, which has symptoms closely related to Dengue Fever.
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2 dead in China from unusual bird flu strain - CNN.com - 0 views

www.cnn.com/...index.html
shared by Jeremiah Williamson on 02 Apr 13 - No Cached
  • Jeremiah Williamson on 02 Apr 13
     
    The article shows a new strain of bird flu H7N9.  The virus has a hard time infecting humans, but for every one human infected there are thousands of birds infected.  This strain is less harmful than H5N1, but still one death has been reported.
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The Flu Virus Can Tell Time. Here's Why You Should Care | Popular Science - 0 views

www.popsci.com/...time-heres-why-you-should-care
shared by Alison Prodzinski on 02 Apr 13 - No Cached
  • Influenza can tell time, and it choreographs its actions according to a strict schedule.
  • The virus has to orchestrate its actions carefully--if it moves too fast, it won’t have time to make new copies of itself, and if it moves too slowly, it might be stopped by immune defenses.
  • To fight it, they tricked the virus into changing the amount of time it took to gather the protein. First, they made it acquire the protein too quickly, which caused the flu to leave the cell before it had made enough copies of itself. In this case, the cells were lung epithelial cells. Then they altered it to leave too late, giving immune cells enough time to respond and kill the virus before it escaped.
  • Alison Prodzinski on 02 Apr 13
     
    Viruses are smarter then we ever imagined!! Researchers have realized that virus have their own time-clock. Virus's take about 8 hours to sufficiently make copies and overtake our bodies. They slowly build in our bodies, before the body actually realizes what is happening - by that time it is too late. Researchers are now tricking viruses into changing the time needed to overtake the body - making the body react quicker and kill the virus. The flu vaccine is still the best way, however, if we can fool the time it takes for a virus to overthrow the body - can we stop it in general? 
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Dirtying Up Our Diets - 0 views

www.nytimes.com/...a-little-dirt-to-our-diet.html
shared by Amy Jorgenson on 02 Apr 13 - No Cached
  • Amy Jorgenson on 02 Apr 13
     
    Even though this article is taken from the opinions page of the NY Times, it still discusses a rather important issue. Sometimes the old saying "A little dirt never hurt" rings oh so true.
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For Gastronomists, a Go-To Microbiologist - 0 views

www.nytimes.com/...ts-a-go-to-microbiologist.html
shared by Amy Jorgenson on 02 Apr 13 - No Cached
  • Amy Jorgenson on 02 Apr 13
     
    Possibly a budding career field for future microbiologists?
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Researchers Find Immunity Protein That Ramps Up Inflammation, and Agents That Can Block It - 0 views

www.sciencedaily.com/...130331165601.htm
shared by Abdirizak Abdi on 01 Apr 13 - No Cached
  • Abdirizak Abdi on 01 Apr 13
     
    Scientist have a found innate protein that increases inflammation and,agents that block it, resulting in increased in survival and improved lung function in animal models pneumonia. "The F-box protein Fbxo3, and other related proteins, represent ideal targets for treatment of acute lung injury, because it controls the innate immune response, is upstream of important inflammatory signaling pathways, and is more selective than traditional drugs that regulate protein turnover" noted Mark T Gladwin M.D., chief of the Division of Pulmonary, Allergy and Critical Care Medicine, Pitt School of Medicine.
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Onions and Flu - Can Raw Onions Prevent the Flu? - Urban Legends - 1 views

urbanlegends.about.com/...e_flu_facts_onions_and_flu.htm
shared by Tiffany Arcand on 25 Mar 13 - No Cached
  • Tiffany Arcand on 25 Mar 13
     
    Although this article does not come from the most scholarly source, my dad and I were talking and he mentioned that if you slice an onion and place it in the corner of the room, it will "absorb" any flu virus present. This is not true.
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Scientists Find Bacteria Where It Isn't Supposed to Be: The Brain - The Daily Beast - 0 views

www.thedailybeast.com/...-supposed-to-be-the-brain.html
shared by Tiffany Arcand on 01 Apr 13 - No Cached
  • The researchers found these bacterial molecules in brain samples from people with HIV, as well as people with no known infectious disease but who had undergone brain surgery
    • Tiffany Arcand
      Tiffany Arcand on 01 Apr 13
       
      So in immunocompromised individuals, as well as those whose brains have been exposed to the operating room - which as we learned in class, can still house bacteria despite all precautions taken.
    • Tiffany Arcand
      Tiffany Arcand on 01 Apr 13
       
      Sneaky, sneaky viruses!
  • If living bacteria help to maintain brain health in some way, disruptions to them, for example from antibiotics, could contribute to disease
    • Tiffany Arcand
      Tiffany Arcand on 01 Apr 13
       
      It will be interesting to see what they discover as they research this more. My guess it that the bacteria in the brain are both beneficial and harmful.
  • ...4 more annotations...
  • Dyes injected into the brain, meanwhile, tended not to appear in the body
    • Tiffany Arcand
      Tiffany Arcand on 01 Apr 13
       
      Wouldn't a shot into the brain kill you, or at least be very painful?
  • Last fall, for instance, researchers found male genetic material in the brains of women (who almost certainly were not born with it). Perhaps during pregnancy, the scientists suggested, cells from male fetuses had crossed the placenta and entered the women’s bodie
  • Scientists have discovered, for instance, that HIV hides inside white blood cells that enter the brain in order to look for pathogens; they call this the Trojan horse strategy
  • a mind-bending concept
  • Tiffany Arcand on 01 Apr 13
     
    Bacteria Can Bypass Blood-Brain Barrier? It's a surprise to researchers who believed the brain-blood barrier created an impenetrable fortress. How are molecules from dirt getting into white matter-and what are they doing up there? 
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Scores of Tulsa dental patients tested for hepatitis, HIV exposure - CNN.com - 0 views

www.cnn.com/...index.html HIV hepatitis
shared by Nate Scheibe on 31 Mar 13 - No Cached
  • Nate Scheibe on 31 Mar 13
     
    A sad reminder of why we use proper sterilization techniques.
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Medical laboratory and biomedical science: C. difficile outbreak at Ottawa hospital - 0 views

clinical-laboratory.blogspot.com/...ratory-c-diff-outbreak-at.html
shared by Tiffany Arcand on 31 Mar 13 - No Cached
  • Tiffany Arcand on 31 Mar 13
     
    The Ottawa Hospital has been severely criticized in a report about practices and hygiene. The report was commissioned following a high number of Clostridium difficile cases over a two year period. This is especially relevant to me because it encompasses both CLS and microbiology.
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Genetically Engineered Immune Cells Found to Rapidly Clear Leukemia Tumors: Scientific ... - 0 views

www.scientificamerican.com/article.cfm leukemia
shared by Whitney Hopfauf on 31 Mar 13 - No Cached
  • shown promise against chronic leukemia, but there were
  • doubts about whether it could take on the faster-growing acute lymphoblastic
  • By the time the man started the trial, 70% of his bone marrow was tumor.
  • ...3 more annotations...
  • ‘chimeric antigen receptor
  • ’, or CAR, that would target cells expressing a protein called CD19.
  • treatment had driven his cancer into remission
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Estrogen Plus Progestin Use Linked With Increased Breast Cancer Incidence and Mortality - 1 views

www.sciencedaily.com/...130329161238.htm
shared by Abdirizak Abdi on 30 Mar 13 - No Cached
  • Abdirizak Abdi on 30 Mar 13
     
    Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be higher for hormone therapy users as well, according to a study
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Poultry probiotic cuts its coat to beat bad bacteria - 0 views

phys.org/...obiotic-coat-bad-bacteria.html probiotics
shared by Elijah Velasquez on 30 Mar 13 - No Cached
  • Elijah Velasquez on 30 Mar 13
     
    The probioitc L. johnsonii has the ability to alter its coat. The alteration protects the bacteria from stomach acids and helps them come together to form biofilms. This increases colonization within the gut and could prevent C. perfringens from colonising the gut. This is a very interesting approach and is comparable to the actions of natural flora within humans.
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How Pigs on Antibiotics Are Making Superbugs Stronger | Popular Science - 0 views

www.popsci.com/...-are-making-superbugs-stronger
shared by Alison Prodzinski on 28 Mar 13 - No Cached
  • new research suggests it’s the animals, and the drugs we feed them
  • MRSA started out as a drug-defeatable bug and then transferred into the pig population, where it developed resistance to two common forms of antibiotics
  • “[It’s] like watching the birth of a superbug,”
  • ...1 more annotation...
  • humans have supplied a strong force through the excessive use of antibiotic drugs in farm animal production,
  • Alison Prodzinski on 28 Mar 13
     
    MSRA could be defeated when first discovered. However, it was transferred to the pig population and went crazy after that. Humans over immunize animals and make super-bugs from inappropriate and overuse of antibiotics.  New tests are being done with bacteria being injected into other hosts - which then can be used to kill MRSA. This method could find new and natural antibiotics that could fight various forms of drug-resistant superbugs!
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Brand-New Vaccine Strategy Works Against Herpes, And Potentially HIV | Popular Science - 0 views

www.popsci.com/...rpes-and-may-do-whole-lot-more
shared by Alison Prodzinski on 28 Mar 13 - No Cached
  • The Yale team’s “prime and pull” method is focused on exactly that. Working with mice, the researchers found a way to “prime” T cells to fight a certain kind of infection
  • through conventional vaccination that causes a system-wide immune response.
  • The “prime and pull” technique could potentially be used to combat any infectious agent that enters the body through any specific tissue--agents like the human immunodeficiency virus (HIV) that causes AIDS.
  • Alison Prodzinski on 28 Mar 13
     
    Manipulating T-Cells to fight certain infections, then pulling them out of the body as to not harm anything - because they can spread nasty diseases in places like the central nervous system.  They are now testing these T-cells against HIV. This could be revolutionary - in that the 'Prime and Pull' method could be used over and over without harming the person.  Just proof of how cool T-cells are!! Both useful and harmful if used inappropriately.
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