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Richard Herron

Child born with HIV cured by US doctors | Society | The Guardian - 0 views

www.guardian.co.uk/...us-doctors-cure-child-born-hiv

virology child hiv

shared by Richard Herron on 04 Mar 13 - No Cached
  • Doctors in the US have made medical history by effectively curing a child born with HIV, the first time such a case has been documented.
  • Dr Hannah Gay, who cared for the child at the University of Mississippi medical centre, told the Guardian the case amounted to the first "functional cure" of an HIV-infected child.
  • but it is likely that a tiny amount remains in their body.
  • ...3 more annotations...
  • ypically, women with HIV are given antiretroviral drugs during pregnancy to minimise the amount of virus in their blood. Their newborns go on courses of drugs too, to reduce their risk of infection further. The strategy can stop around 98% of HIV transmission from mother to child.
    • Richard Herron
      Richard Herron on 04 Mar 13
       
      I had no idea modern medicine was this effective against transmission from mother to child.
  • "It is far too early for anyone to try stopping effective therapy just to see if the virus comes back," she said.
Katelyn Madigan

First documented case of child cured of HIV - 0 views

www.sciencedaily.com/...130303172640.htm

microbiology immune HIV child

shared by Katelyn Madigan on 04 Mar 13 - No Cached
  • i diagnosed with HIV at birth and immediately put on antiretroviral therapy.
  • brought back into care at 23 months, despite being off treatment for five months, the child was found to have an undetectable viral load
  • d today no signs of HIV infection in the child can be detected by the most sensitive means available.
  • ...2 more annotations...
  • physician was able to treat his leukemia with a stem-cell transplant from a person who was born with a genetic mutation causing immunity to HIV infection. Following the transplant, Mr. Brown was able to stop HIV treatment without experiencing a return of his HIV disease
  • achieved by antiretroviral therapy alone
Emma Radzak

First vaccine to help control some autism symptoms - 0 views

www.sciencedaily.com/...130424112309.htm

shared by Emma Radzak on 27 Apr 13 - No Cached
  • Emma Radzak on 27 Apr 13
     
    A vaccine to combat the microorganism C. bolteae may be the solution for alleviating digestion symptoms often associated with autism. Children with autism have been known to have higher levels of this organism than that of a healthy child. It is assumed that toxins produced by the C. bolteae may be associated with severe symptoms that autistic children typically have, such as diarrhea. I found it ironic that many people still think that vaccines cause autism, and here is a vaccine to assist in alleviating the digestive symptoms associated with it.
  • Emma Radzak on 27 Apr 13
     
    A vaccine to combat the microorganism C. bolteae may be the solution for alleviating digestion symptoms often associated with autism. Children with autism have been known to have higher levels of this organism than that of a healthy child. It is assumed that toxins produced by the C. bolteae may be associated with severe symptoms that autistic children typically have, such as diarrhea. I found it ironic that many people still think that vaccines cause autism, and here is a vaccine to assist in alleviating the digestive symptoms associated with it.
loryn_micro

Sucking your childs pacifier to clean it may have health benefits - 0 views

well.blogs.nytimes.com/...iers-may-be-your-childs-friend

shared by loryn_micro on 06 May 13 - No Cached
  • loryn_micro on 06 May 13
     
    Reduced allergies in children
Whitney Hopfauf

First documented case of child cured of HIV - 0 views

www.sciencedaily.com/...130303172640.htm

virus

shared by Whitney Hopfauf on 04 Mar 13 - No Cached
  • Whitney Hopfauf on 04 Mar 13
     
    Exciting when AIDS research takes a step forward. However, is it true that although they cannot detect the virus, it may lie dormant? How sensitive are those tests? There was a case of a man who had HIV and leukemia and so they treated him with a bone marrow transplant from someone who was resistant to HIV. The man was said to be cured but there were later debates on the validity. 
Casey Finnerty

Baby With H.I.V. Is Reported Cured - NYTimes.com - 1 views

www.nytimes.com/...-cured-of-hiv-doctors-say.html

HIV microbiology virology immunity

shared by Casey Finnerty on 07 Mar 13 - No Cached
  • If the report is confirmed, the child born in Mississippi would be only the second well-documented case of a cure in the world
  • Typically a newborn with an infected mother would be given one or two drugs as a prophylactic measure. But Dr. Gay said that based on her experience, she almost immediately used a three-drug regimen aimed at treatment, not prophylaxis, not even waiting for the test results confirming infection.
  • Virus levels rapidly declined with treatment and were undetectable by the time the baby was a month old. That remained the case until the baby was 18 months old, after which the mother stopped coming to the hospital and stopped giving the drugs.
  • ...10 more annotations...
  • Dr. Gay contacted Dr. Katherine Luzuriaga, an immunologist at the University of Massachusetts,
  • Dr. Steven Deeks, professor of medicine at the University of California, San Francisco, said if the reservoir never established itself, then he would not call it a true cure, though this was somewhat a matter of semantics. “Was there enough time for a latent reservoir, the true barrier to cure, to establish itself?” he said.
  • One hypothesis is that the drugs killed off the virus before it could establish a hidden reservoir in the baby.
  • They found tiny amounts of some viral genetic material but no virus able to replicate, even lying dormant in so-called reservoirs in the body.
  • “For pediatrics, this is our Timothy Brown,” said Dr. Deborah Persaud, associate professor at the Johns Hopkins Children’s Center and lead author of the report on the baby. “It’s proof of principle that we can cure H.I.V. infection if we can replicate this case.”
  • Dr. Hannah B. Gay, an associate professor of pediatrics,
  • The results have not yet been published in a peer-reviewed medical journal.
  • The baby, born in rural Mississippi, was treated aggressively with antiretroviral drugs starting around 30 hours after birth, something that is not usually done. If further study shows this works in other babies, it will almost certainly be recommended globally.
  • those reports and this new one could suggest there is something different about babies’ immune systems, said Dr. Joseph McCune of the University of California, San Francisco.
  • the results could lead to a new protocol for quickly testing and treating infants.
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