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Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Frontiers in Antimicrobials, Resistance and Chemotherapy publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Antimicrobials, Resistance and Chemotherapy.

Scientists have recently discovered how pili are formed, giving another potential target for antimicrobial medications

A rather novel discovery in the field of pili biogenesis. This also appears to be a big steeping stone in the development of potential new antibiotics for cystitis (bladder inflammation a.k.a urinary tract infections).

With antibiotic resistance looming, the failure of drug companies to develop new drugs to fight gram-negative bacteria could potentially lead to millions of deaths just from a common cold or from the flu. Drug companies cannot turn out new antimicrobials fast enough, and the ones that they do get out to the public cost billions of dollars.

Scary to think that we're all at risk!

A specific approach to target the genes that are involved in wound healing seems like a progressive approach for several skin disorders.

E. coli has been known to cause G.I tract infections for a long time, but now studies have been finding the same strain in the urinary tract as well. This is leading to a progressive antimicrobial resistance that is combining the effects of increased UTI antibiotic usage and agricultural antibiotic use against the same strain of E. coli.

The main therapy of Gas Gangrene is amputation even before systemic infection, hyperbaric oxygen, or penicillin treatment therapy. Combination therapies were tested on mice with Gas Gangrene, which proved that metronidazole and penicillin together produced a higher mortality rate than that of metronidazole alone. But, metronidazole and clindamycin were more effective than penicillin alone. So some combination therapies are effective, while others are more dangerous.

This was the first study to use a light-activated substance to destroy MRSA in wounds

very interesting...the same mechanism HIV uses to infect cells can be manufactured and used to destroy antibiotic-resistant bacteria

Although nanosilver has effective antimicrobial properties against certain pathogens, it can cause other potentially harmful organisms to rapidly adapt and flourish, a new study reveal...Hmmm!!