Prospective study of serum vitamin D and cancer mortality in the United States.
Freedman DM, Looker AC, Chang SC, Graubard BI.
J Natl Cancer Inst. 2007 Nov 7;99(21):1594-602. Epub 2007 Oct 30.
PMID: 17971526
doi:10.1093/jnci/djm204
CONCLUSIONS: Our results do not support an association between 25(OH)D and total cancer mortality, although there was an inverse relationship between 25(OH)D levels and colorectal cancer mortality.
Meta-analysis: longitudinal studies of serum vitamin D and colorectal cancer risk.
Yin L, Grandi N, Raum E, Haug U, Arndt V, Brenner H.
Aliment Pharmacol Ther. 2009 Jul 1;30(2):113-25. Epub 2009 Apr 15.
PMID: 19392870
DOI: 10.1111/j.1365-2036.2009.04022.x
Conclusions Our results support suggestions that serum 25(OH)D is inversely related to CRC risk.
Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer
K Ng, B M Wolpin, J A Meyerhardt, K Wu, A T Chan, B W Hollis, E L Giovannucci, M J Stampfer, W C Willett and C S Fuchs
Br J Cancer 101: 916-923; advance online publication, August 18, 2009; doi:10.1038/sj.bjc.6605262
Calcium plus vitamin D supplementation and the risk of colorectal cancer.
Wactawski-Wende J, Kotchen JM, Anderson GL, Assaf AR, Brunner RL, O'Sullivan MJ, Margolis KL, Ockene JK, Phillips L, Pottern L, Prentice RL, Robbins J, Rohan TE, Sarto GE, Sharma S, Stefanick ML, Van Horn L, Wallace RB, Whitlock E, Bassford T, Beresford SA, Black HR, Bonds DE, Brzyski RG, Caan B, Chlebowski RT, Cochrane B, Garland C, Gass M, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Jackson RD, Johnson KC, Judd H, Kooperberg CL, Kuller LH, LaCroix AZ, Lane DS, Langer RD, Lasser NL, Lewis CE, Limacher MC, Manson JE; Women's Health Initiative Investigators.
N Engl J Med. 2006 Feb 16;354(7):684-96. Erratum in: N Engl J Med. 2006 Mar 9;354(10):1102.
PMID: 16481636
Conclusions Daily supplementation of calcium with vitamin D for seven years had no effect on the incidence of colorectal cancer among postmenopausal women. The long latency associated with the development of colorectal cancer, along with the seven-year duration of the trial, may have contributed to this null finding. Ongoing follow-up will assess the longer-term effect of this intervention.
Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer.
Ng K, Meyerhardt JA, Wu K, Feskanich D, Hollis BW, Giovannucci EL, Fuchs CS.
J Clin Oncol. 2008 Jun 20;26(18):2984-91.
PMID: 18565885
DOI: 10.1200/JCO.2007.15.1027
Conclusion Among patients with colorectal cancer, higher prediagnosis plasma 25(OH)D levels were associated with a significant improvement in overall survival. Further study of the vitamin D pathway and its influence on colorectal carcinogenesis and cancer progression is warranted.
Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B.
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes.
Am J Clin Nutr. 2006 Jul;84(1):18-28. Review.
PMID: 16825677
Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF.
Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis.
Am J Prev Med. 2007 Mar;32(3):210-6.
PMID: 17296473
A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer.
Wu K, Feskanich D, Fuchs CS, Willett WC, Hollis BW, Giovannucci EL.
J Natl Cancer Inst. 2007 Jul 18;99(14):1120-9. Epub 2007 Jul 10.
PMID: 17623801