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Matti Narkia

Long-term effects of giving nursing home residents bread fortified with 125 {micro}g (5... - 0 views

www.ajcn.org/...ajcn.2008.26890v1

2009 February ajcn study research clinical_trial humans nursing_home resident elderly old older vitamin D vitamin_D fortified bread fortified_bread calcium bone bone_health _bone_density BMD 25ohd calcidiol osteoporosis nutrition medline Vieth

shared by Matti Narkia on 25 Aug 09 - Cached
  • Matti Narkia on 25 Aug 09
     
    Long-term effects of giving nursing home residents bread fortified with 125 {micro}g (5000 IU) vitamin D3 per daily serving. Mocanu V, Stitt PA, Costan AR, Voroniuc O, Zbranca E, Luca V, Vieth R. Am J Clin Nutr. 2009 Feb 25. [Epub ahead of print] PMID: 19244376
Matti Narkia

Vitamin D Supplementation and Total Mortality: A Meta-analysis of Randomized Controlled... - 0 views

archinte.ama-assn.org/...1730

2007 September study review meta-analysis clinical_trials rcts humans vitamin_D supplementation total mortality all-cause all-causes nutrition medline

shared by Matti Narkia on 06 Sep 09 - Cached
  • Matti Narkia on 06 Sep 09
     
    Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Autier P, Gandini S. Arch Intern Med. 2007 Sep 10;167(16):1730-7. Review. PMID: 17846391 Conclusions Intake of ordinary doses of vitamin D supplements seems to be associated with decreases in total mortality rates. The relationship between baseline vitamin D status, dose of vitamin D supplements, and total mortality rates remains to be investigated. Population-based, placebo-controlled randomized trials with total mortality as the main end point should be organized for confirming these findings.
Matti Narkia

Vitamin D2 Is Much Less Effective than Vitamin D3 in Humans -- Armas et al. 89 (11): 53... - 0 views

jcem.endojournals.org/...5387

2004 November study research clinical_trial rct humans vitamin_D vitamin_D2 vitamin_D3 efficacy comparison 25ohd Heaney Hollis supplementation nutrition medline

shared by Matti Narkia on 03 Sep 09 - Cached
  • Matti Narkia on 03 Sep 09
     
    Vitamin D2 is much less effective than vitamin D3 in humans. Armas LA, Hollis BW, Heaney RP. J Clin Endocrinol Metab. 2004 Nov;89(11):5387-91. PMID: 15531486 Vitamin D2 potency is less than one third that of vitamin D3. Physicians resorting to use of vitamin D2 should be aware of its markedly lower potency and shorter duration of action relative to vitamin D3.
Matti Narkia

Vitamin D and calcium supplementation reduces cancer risk: results of a randomized tria... - 0 views

www.ajcn.org/...1586

2007 March ajcn Lappe Heaney study research clinical_trial rct humans vitamin_D 25ohs calcidiol cancer women calcium vitamin_D3 supplementation nutrition medline risk prevention incidence cancer_risk risk_reduction cancer_prevention postmenopausal

shared by Matti Narkia on 28 Aug 09 - Cached
  • Matti Narkia on 28 Aug 09
     
    Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP. Am J Clin Nutr. 2007 Jun;85(6):1586-91. Erratum in: Am J Clin Nutr. 2008 Mar;87(3):794. PMID: 17556697 Conclusions: Improving calcium and vitamin D nutritional status substantially reduces all-cancer risk in postmenopausal women.
Matti Narkia

Prevention of Nonvertebral Fractures With Oral Vitamin D and Dose Dependency: A Meta-an... - 0 views

archinte.ama-assn.org/...551

2009 March study review meta-analysis clinical_trials rtcs humans vitamin D vitamin_D supplementation supplements supplemental nonvertebral fractures bone health nutrition prevention osteoporosis dose-dependent medline Bischoff-Ferrari Willett

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  • Matti Narkia on 25 Aug 09
     
    Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowski J. Arch Intern Med. 2009 Mar 23;169(6):551-61. PMID: 19307517 Conclusion Nonvertebral fracture prevention with vitamin D is dose dependent, and a higher dose should reduce fractures by at least 20% for individuals aged 65 years or older.
Matti Narkia

Vitamin D supplementation during Antarctic winter. - Am J Clin Nutr. 2009 Ap - 0 views

www.ajcn.org/...1092

2009 April ajcn study research clinical_trial rct humans vitamin D vitamin_D supplementation Antarctic winter 25ohd calcidiol dosing doses dosage supplements nutrition medline

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  • Matti Narkia on 25 Aug 09
     
    Vitamin D supplementation during Antarctic winter. Smith SM, Gardner KK, Locke J, Zwart SR. Am J Clin Nutr. 2009 Apr;89(4):1092-8. Epub 2009 Feb 18. PMID: 19225122 doi:10.3945/ajcn.2008.27189
Matti Narkia

Vitamin D supplementation improves cytokine profiles in patients with congestive heart ... - 0 views

www.ajcn.org/...754

2006 supplements cytokine profiles congestive heart failure CHF nutrition zittermann rct medicine medline science study research peer-reviewed cardiolology 25(oh)d 25-hydroxyvitamind calcidiol cytokines inflammation impor vitamin_D clinical_trial

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  • Matti Narkia on 25 Aug 09
     
    Schleithoff SS, Zittermann A, Tenderich G, Berthold HK, Stehle P, Koerfer R. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial.Am J Clin Nutr. 2006 Apr;
Matti Narkia

A New Active Vitamin D, ED-71, Increases Bone Mass in Osteoporotic Patients under Vitam... - 0 views

jcem.endojournals.org/...5031

ed-71 active osteoporosis bmd hip lumbar medicine rct research science medline peer-reviewed study analogue imported delicious vitamin_D clinical_trial

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  • Matti Narkia on 25 Aug 09
     
    Matsumoto T, Miki T, Hagino H, Sugimoto T, Okamoto S, Hirota T, Tanigawara Y, Hayashi Y, Fukunaga M, Shiraki M, Nakamura T. A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: a randomized, double-
Matti Narkia

Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect l... - 0 views

www.ajcn.org/...288

2001 February Cholecalciferol calcidiol hypercalciuria toxicity LOAEL efficacy safety intake nutrition Vieth rct research study vitamin_D vitamin_D3 clinical_trial 25ohd supplementation

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  • Matti Narkia on 25 Aug 09
     
    Vieth R, Chan PC, MacFarlane GD. Efficacy and safety of vitamin D3 intake exceeding the lowest observedadverse effect level. Am J Clin Nutr. 2001 Feb;73(2):288-94. PMID: 11157326
Matti Narkia

Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalcif... - 0 views

www.ajcn.org/...204

2003 January ajcn study research clinical_trial Heaney Holick vitamin_D cholecalciferol 25ohd calcidiol PTH dosing dosage dose-response nutrition supplementation UL tolerable upper input level intake usage

shared by Matti Narkia on 25 Aug 09 - Cached
  • Matti Narkia on 25 Aug 09
     
    Conclusions: Healthy men seem to use 3000-5000 IU cholecalciferol/d, apparently meeting > 80% of their winter cholecalciferol need with cutaneously synthesized accumulations from solar sources during the preceding summer months. Current recommended vitamin D inputs are inadequate to maintain serum 25-hydroxycholecalciferol concentration in the absence of substantial cutaneous production of vitamin D. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ. Am J Clin Nutr. 2003 Jan;77(1):204-10. Erratum in: Am J Clin Nutr. 2003 Nov;78(5):1047. PMID: 12499343
Matti Narkia

Dose response to vitamin D supplementation among postmenopausal African American women.... - 0 views

www.ajcn.org/...1657

2007 December ajcn Aloia study research clinical_trial humans African_American women black postmenopausal vitamin D vitamin_D 25ohd calcidiol supplementation dosing dosage dose-response deficiency osteoporosis nutrition medline

shared by Matti Narkia on 25 Aug 09 - Cached
  • Matti Narkia on 25 Aug 09
     
    Dose response to vitamin D supplementation among postmenopausal African American women. Talwar SA, Aloia JF, Pollack S, Yeh JK. Am J Clin Nutr. 2007 Dec;86(6):1657-62. PMID: 18065583
Matti Narkia

Supplements of 20 microg/d cholecalciferol optimized serum 25-hydroxyvitamin D concentr... - 0 views

jn.nutrition.org/...540

2009 March jn study research clinical_trial rct humans women vitamin D vitamin_D supplementation supplements 25OHD calcidiol optimizing level levels nutrition medline winter supplemental

shared by Matti Narkia on 25 Aug 09 - Cached
  • Matti Narkia on 25 Aug 09
     
    Supplements of 20 microg/d cholecalciferol optimized serum 25-hydroxyvitamin D concentrations in 80% of premenopausal women in winter.\nNelson ML, Blum JM, Hollis BW, Rosen C, Sullivan SS.\nJ Nutr. 2009 Mar;139(3):540-6. Epub 2009 Jan 21.\nPMID: 19158226
Matti Narkia

Estimation of the dietary requirement for vitamin D in healthy adults. - 0 views

www.ajcn.org/...1535

2008 December ajcn study research clinical_trial rct humans vitamin D vitamin_D dietary requirement requirements nutrition dose dosage dosing medline wintertime winter 25ohd calcidiol

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  • Matti Narkia on 25 Aug 09
     
    Estimation of the dietary requirement for vitamin D in healthy adults.\nCashman KD, Hill TR, Lucey AJ, Taylor N, Seamans KM, Muldowney S, Fitzgerald AP, Flynn A, Barnes MS, Horigan G, Bonham MP, Duffy EM, Strain JJ, Wallace JM, Kiely M.\nAm J Clin Nutr. 2008 Dec;88(6):1535-42.\nPMID: 19064513 [
Matti Narkia

Decreased bioavailability of vitamin D in obesity -- Wortsman et al. 72 (3): 690 -- Ame... - 0 views

www.ajcn.org/...690

2000 September ajcn study research clinical_trial humans vitamin_D obesity UV UVB radiation vitamin_D2 supplementation bioavailability nutrition medline 25ohd body_fat Holick

shared by Matti Narkia on 08 Dec 09 - Cached
  • Matti Narkia on 08 Dec 09
     
    Decreased bioavailability of vitamin D in obesity. Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Am J Clin Nutr. 2000 Sep;72(3):690-3. Erratum in: Am J Clin Nutr. 2003 May;77(5):1342. PMID: 10966885 Conclusions: Obesity-associated vitamin D insufficiency is likely due to the decreased bioavailability of vitamin D3 from cutaneous and dietary sources because of its deposition in body fat compartments.
Matti Narkia

Evidence for alteration of the vitamin D-endocrine system in obese subjects. - Journal ... - 0 views

www.jci.org/111971

1985 July jci study research clinical_trial humans obesity vitamin_D vitamin D-endocrine system alteration obese subjects nutrition medline PTH 25ohd calcitriol

shared by Matti Narkia on 08 Dec 09 - Cached
  • Matti Narkia on 08 Dec 09
     
    Evidence for alteration of the vitamin D-endocrine system in obese subjects. Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S. J Clin Invest. 1985 Jul;76(1):370-3. PMID: 2991340 The results provide evidence that alteration of the vitamin D-endocrine system in obese subjects is characterized by secondary hyperparathyroidism which is associated with enhanced renal tubular reabsorption of calcium and increased circulating 1,25(OH)2D. The reduction of serum 25-OHD in them is attributed to feedback inhibition of hepatic synthesis of the precursor by the increased serum 1,25(OH)2D.
Matti Narkia

Vitamin D supplementation reduces insulin resistance in South Asian women living in New... - 0 views

journals.cambridge.org/...displayAbstract

2009 September bjn study research clinical_trial rct humans South Asian women New_Zealand vitamin_D supplementation reduces improves insulin resistance insulin_resistance nutrition diabetes type_2 medline

shared by Matti Narkia on 04 Dec 09 - Cached
  • Matti Narkia on 04 Dec 09
     
    Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient - a randomised, placebo-controlled trial. von Hurst PR, Stonehouse W, Coad J. Br J Nutr. 2009 Sep 28:1-7. [Epub ahead of print] PMID: 19781131 In conclusion, improving vitamin D status in insulin resistant women resulted in improved IR and sensitivity, but no change in insulin secretion. Optimal vitamin D concentrations for reducing IR were shown to be 80-119 nmol/l, providing further evidence for an increase in the recommended adequate levels. Registered Trial No. ACTRN12607000642482.
Matti Narkia

Benefit-risk assessment of vitamin D supplementation. - Osteoporos Int. 2009 Dec 3. - S... - 0 views

www.springerlink.com/...g18x734546417446

2009 December study review meta-analysis humans rcts clinical_trials vitamin_D supplementation falls fractures hypercalcemia optimal dose optimal_dose nutrition Willett Giovannucci Bischoff-Ferrari recommendations Dawson-Hughes medline

shared by Matti Narkia on 07 Dec 09 - Cached
  • Matti Narkia on 07 Dec 09
     
    Benefit-risk assessment of vitamin D supplementation. Bischoff-Ferrari HA, Shao A, Dawson-Hughes B, Hathcock J, Giovannucci E, Willett WC. Osteoporos Int. 2009 Dec 3. [Epub ahead of print] PMID: 19957164 Conclusion Our analysis suggests that mean serum 25(OH)D levels of about 75 to 110 nmol/l provide optimal benefits for all investigated endpoints without increasing health risks. These levels can be best obtained with oral doses in the range of 1,800 to 4,000 IU vitamin D per day; further work is needed, including subject and environment factors, to better define the doses that will achieve optimal blood levels in the large majority of the population.
Matti Narkia

The Bioavailability of Vitamin D from Fortified Cheeses and Supplements Is Equivalent i... - 0 views

jn.nutrition.org/...1365

2008 July jn study research clinical_trial rct humans vitamin_D supplementation supplements vs. versus fortified cheddar cheese fortification comparison absorption nutrition Vieth Wagner bioavailability 25ohd status medline

shared by Matti Narkia on 19 Dec 09 - Cached
  • Matti Narkia on 19 Dec 09
     
    The bioavailability of vitamin D from fortified cheeses and supplements is equivalent in adults. Wagner D, Sidhom G, Whiting SJ, Rousseau D, Vieth R. J Nutr. 2008 Jul;138(7):1365-71. PMID: 18567762 Compared with baseline, serum parathyroid hormone decreased with both fortification (P = 0.003) and supplementation (P = 0.012). These data demonstrate that vitamin D is equally bioavailable from fortified hard cheeses and supplements, making cheese suitable for vitamin D fortification.
Matti Narkia

Bread Fortified with Cholecalciferol Increases the Serum 25-Hydroxyvitamin D Concentrat... - 0 views

jn.nutrition.org/...123

2006 January study research clinical_trial rct humans women vitamin_D vitamin_D3 fortified bread fortification bioavailability absorption status 25ohd supplement supplements nutrition comparison Lamberg-Allardt medline

shared by Matti Narkia on 19 Dec 09 - Cached
  • Matti Narkia on 19 Dec 09
     
    Bread fortified with cholecalciferol increases the serum 25-hydroxyvitamin D concentration in women as effectively as a cholecalciferol supplement. Natri AM, Salo P, Vikstedt T, Palssa A, Huttunen M, Kärkkäinen MU, Salovaara H, Piironen V, Jakobsen J, Lamberg-Allardt CJ. J Nutr. 2006 Jan;136(1):123-7. PMID: 16365070 Both fortified breads increased serum 25-hydroxyvitamin D concentration as effectively as the cholecalciferol supplement. Supplementation or fortification did not affect serum intact parathyroid hormone concentration or urinary calcium excretion. In conclusion, fortified bread is a safe and feasible way to improve vitamin D nutrition.
Matti Narkia

A randomised comparison of increase in serum 25-hydroxyvitamin D concentratio... - 0 views

journals.cambridge.org/...displayFulltext

2007 September bjcn study research clinical_trial rct vitamin_D vitamin_D3 multivitamin tablets fish oil capsules oil-based absorption nutrition medline comparison 25ohd increase vs. versus

shared by Matti Narkia on 19 Dec 09 - Cached
  • Matti Narkia on 19 Dec 09
     
    A randomised comparison of increase in serum 25-hydroxyvitamin D concentration after 4 weeks of daily oral intake of 10 microg cholecalciferol from multivitamin tablets or fish oil capsules in healthy young adults. Holvik K, Madar AA, Meyer HE, Lofthus CM, Stene LC. Br J Nutr. 2007 Sep;98(3):620-5. Epub 2007 Apr 24. PMID: 17456248 We conclude that fish oil capsules and multivitamin tablets containing 10 microg cholecalciferol administered over a 4-week period produced a similar mean increase in s-25(OH)D concentration.
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