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jmfinizio

MyPillow CEO hints at scrapped plan to replace CIA director with Trump loyalist - CNNPo... - 0 views

www.cnn.com/...index.html

CIA Trump Director

shared by jmfinizio on 17 Jan 21 - No Cached
  • A Trump ally's notes visible as he visited the West Wing on Friday revealed a suggestion to replace the current CIA director with the current acting chief of staff at the Pentagon
  • Patel, who has held a number of senior jobs in the administration, was named chief of staff to Miller a few days after the general election and is widely viewed as a Trump loyalist.
  • Trump has been on the verge of firing CIA Director Gina Haspel several times only to be pulled back from the brink,
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  • he and others concocted a plan to terminate Haspel and put Patel in charge of the CIA.
  • Miller was named to the top defense job a few days after the election. He and Patel had worked together on counterterrorism issues at the National Security Council earlier in Trump's term.
  • If the idea is truly being considered still with just days to go in Trump's term, trying to put Patel in charge of the country's preeminent intelligence service would require an enormous amount of last-minute bureaucratic gymnastics.
  • Haspel has angered some people in Trump's orbit for stonewalling efforts by Director of National Intelligence John Ratcliffe to declassify documents related to the FBI's Russia investigation.
  • Frankly, he's running out of people who'd even know how to implement those changes. There's no one to do the paperwork, which is pretty complicated for unorthodox personnel moves."
  • The CIA, the Pentagon, the White House and the National Security Council also did not immediately respond to CNN's inquires.
julia rhodes

Federal Brain Science Project Aims To Restore Soldiers' Memory : Shots - Health News : NPR - 0 views

www.npr.org/...ims-to-restore-soldiers-memory

brain science psychology research science memory npr health brain federal

shared by julia rhodes on 30 Nov 13 - No Cached
  • When President Obama announced his plan to explore the mysteries of the human brain seven months ago,
  • BRAIN Initiative will include efforts to restore lost memories in war veterans, create tools that let scientists study individual brain circuits and map the nervous system of the fruit fly.
  • The agency wants to focus on treatments for the sort of brain disorders affecting soldiers who served in Iraq and Afghanistan, according to Dr. Geoffrey Ling, deputy director of DARPA.
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  • DARPA hopes to do that with an implanted device that will take over some functions of the brain's hippocampus, an area that's important to memory. The agency has already used a device that does this in rodents, Ling said, and the goal is to move on to people quickly.
  • We believe that the tools and technologies that will come from this initiative will actually enable all brain scientists to do their work better, faster and with more impact,"
  • For several years now, people with Parkinson's have been able to reduce their tremors with a treatment known as deep brain stimulation.
  • But Dr. Tom Insel, director of the National Institute of Mental Health, said it's important to remember that the immediate goal of the BRAIN Initiative isn't developing treatments, but understanding the inner workings of the most complex system in the universe.
  • "They're interested in the brain as a way to understand who we are, what makes us different and what is special about the human brain."
caelengrubb

Insider Trading - Econlib - 0 views

www.econlib.org/...InsiderTrading.html

shared by caelengrubb on 27 Mar 21 - No Cached
  • Insider trading” refers to transactions in a company’s securities, such as stocks or options, by corporate insiders or their associates based on information originating within the firm that would, once publicly disclosed, affect the prices of such securities.
  • Corporate insiders are individuals whose employment with the firm (as executives, directors, or sometimes rank-and-file employees) or whose privileged access to the firm’s internal affairs (as large shareholders, consultants, accountants, lawyers, etc.) gives them valuable information.
  • Famous examples of insider trading include transacting on the advance knowledge of a company’s discovery of a rich mineral ore (Securities and Exchange Commission v. Texas Gulf Sulphur Co.), on a forthcoming cut in dividends by the board of directors (Cady, Roberts & Co.), and on an unanticipated increase in corporate expenses (Diamond v. Oreamuno).
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  • Such trading on information originating outside the company is generally not covered by insider trading regulation.
  • Insider trading is quite different from market manipulation, disclosure of false or misleading information to the market, or direct expropriation of the corporation’s wealth by insiders.
  • Regulation of insider trading began in the United States at the turn of the twentieth century, when judges in several states became willing to rescind corporate insiders’ transactions with uninformed shareholders.
  • One of the earliest (and unsuccessful) federal attempts to regulate insider trading occurred after the 1912–1913 congressional hearings before the Pujo Committee, which concluded that “the scandalous practices of officers and directors in speculating upon inside and advance information as to the action of their corporations may be curtailed if not stopped.”
  • The Securities Acts of 1933–1934, passed by the U.S. Congress in the aftermath of the stock market crash, though aimed primarily at prohibiting fraud and market manipulation, also targeted insider trading.
  • As of 2004, at least ninety-three countries, the vast majority of nations that possess organized securities markets, had laws regulating insider trading
  • Several factors explain the rapid emergence of such regulation, particularly during the last twenty years: namely, the growth of the securities industry worldwide, pressures to make national securities markets look more attractive in the eyes of outside investors, and the pressure the SEC exerted on foreign lawmakers and regulators to increase the effectiveness of domestic enforcement by identifying and punishing offenders and their associates operating outside the United States.
  • Many researchers argue that trading on inside information is a zero-sum game, benefiting insiders at the expense of outsiders. But most outsiders who bought from or sold to insiders would have traded anyway, and possibly at a worse price (Manne 1970). So, for example, if the insider sells stock because he expects the price to fall, the very act of selling may bring the price down to the buyer.
  • A controversial case is that of abstaining from trading on the basis of inside information (Fried 2003).
  • There is little disagreement that insider trading makes securities markets more efficient by moving the current market price closer to the future postdisclosure price. In other words, insiders’ transactions, even if they are anonymous, signal future price trends to others and make the current stock price reflect relevant information sooner.
  • Accurately priced stocks give valuable signals to investors and ensure more efficient allocation of capital.
  • The controversial question is whether insider trading is more or less effective than public disclosure.
  • Insider trading’s advantage is that it introduces individual profit motives, does not directly reveal sensitive intercorporate information, and mitigates the management’s aversion to disclosing negative information (
  • Probably the most controversial issue in the economic analysis of insider trading is whether it is an efficient way to pay managers for their entrepreneurial services to the corporation. Some researchers believe that insider trading gives managers a monetary incentive to innovate, search for, and produce valuable information, as well as to take risks that increase the firm’s value (Carlton and Fischel 1983; Manne 1966).
  • Another economic argument for insider trading is that it provides efficient compensation to holders of large blocks of stock
  • A common contention is that the presence of insider trading decreases public confidence in, and deters many potential investors from, equity markets, making them less liquid (Loss 1970).
  • Empirical research generally supports skepticism that regulation of insider trading has been effective in either the United States or internationally, as evidenced by the persistent trading profits of insiders, behavior of stock prices around corporate announcements, and relatively infrequent prosecution rates (Bhattacharya and Daouk 2002; Bris 2005).
  • Despite numerous and extensive debates, economists and legal scholars do not agree on a desirable government policy toward insider trading. On the one hand, absolute information parity is clearly infeasible, and information-based trading generally increases the pricing efficiency of financial markets. Information, after all, is a scarce economic good that is costly to produce or acquire, and its subsequent use and dissemination are difficult to control. On the other hand, insider trading, as opposed to other forms of informed trading, may produce unintended adverse consequences for the functioning of the corporate enterprise, the market-wide system of publicly mandated disclosure, or the market for information.
rachelramirez

Experts: Yes, Anti-Refugee Rhetoric Helps ISIS - The Daily Beast - 0 views

www.thedailybeast.com/...fugee-rhetoric-helps-isis.html

Syria Isis

shared by rachelramirez on 30 Nov 15 - No Cached
  • Experts: Yes, Anti-Refugee Rhetoric Helps ISIS
  • “There is no place for bigotry in effective counterterrorism,” Professor James Forest, the director of the graduate program in security studies and interim director of the Center for Terrorism and Security Studies at UMass Lowell
  • Arie W. Kruglanski, professor of psychology at the University of Maryland, has written about how ISIS recruitment strategy is based on psychology, not theology. 
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  • “Counterterrorism tries to do two things,” explained Professor Max Abrahms, a political scientist at Northeastern University who studies terrorism. “You try to neutralize existing terrorists and you try to not breed new ones. The surest way to breed new ones is if you’re indiscriminate—for instance, punishing non-violent, moderate Muslims.” 
Javier E

How Calls for Privacy May Upend Business for Facebook and Google - The New York Times - 0 views

www.nytimes.com/...gle-facebook-data-privacy.html

tech science psychology technology social media Big data privacy democracy

shared by Javier E on 25 Mar 18 - No Cached
  • People detailed their interests and obsessions on Facebook and Google, generating a river of data that could be collected and harnessed for advertising. The companies became very rich. Users seemed happy. Privacy was deemed obsolete, like bloodletting and milkmen
  • It has been many months of allegations and arguments that the internet in general and social media in particular are pulling society down instead of lifting it up.
  • That has inspired a good deal of debate about more restrictive futures for Facebook and Google. At the furthest extreme, some dream of the companies becoming public utilities.
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  • There are other avenues still, said Jascha Kaykas-Wolff, the chief marketing officer of Mozilla, the nonprofit organization behind the popular Firefox browser, including advertisers and large tech platforms collecting vastly less user data and still effectively customizing ads to consumers.
  • The greatest likelihood is that the internet companies, frightened by the tumult, will accept a few more rules and work a little harder for transparency.
  • The Cambridge Analytica case, said Vera Jourova, the European Union commissioner for justice, consumers and gender equality, was not just a breach of private data. “This is much more serious, because here we witness the threat to democracy, to democratic plurality,” she said.
  • Although many people had a general understanding that free online services used their personal details to customize the ads they saw, the latest controversy starkly exposed the machinery.
  • Consumers’ seemingly benign activities — their likes — could be used to covertly categorize and influence their behavior. And not just by unknown third parties. Facebook itself has worked directly with presidential campaigns on ad targeting, describing its services in a company case study as “influencing voters.”
  • “If your personal information can help sway elections, which affects everyone’s life and societal well-being, maybe privacy does matter after all.”
  • some trade group executives also warned that any attempt to curb the use of consumer data would put the business model of the ad-supported internet at risk.
  • “You’re undermining a fundamental concept in advertising: reaching consumers who are interested in a particular product,”
  • If suspicion of Facebook and Google is a relatively new feeling in the United States, it has been embedded in Europe for historical and cultural reasons that date back to the Nazi Gestapo, the Soviet occupation of Eastern Europe and the Cold War.
  • “We’re at an inflection point, when the great wave of optimism about tech is giving way to growing alarm,” said Heather Grabbe, director of the Open Society European Policy Institute. “This is the moment when Europeans turn to the state for protection and answers, and are less likely than Americans to rely on the market to sort out imbalances.”
  • In May, the European Union is instituting a comprehensive new privacy law, called the General Data Protection Regulation. The new rules treat personal data as proprietary, owned by an individual, and any use of that data must be accompanied by permission — opting in rather than opting out — after receiving a request written in clear language, not legalese.
  • the protection rules will have more teeth than the current 1995 directive. For example, a company experiencing a data breach involving individuals must notify the data protection authority within 72 hours and would be subject to fines of up to 20 million euros or 4 percent of its annual revenue.
  • “With the new European law, regulators for the first time have real enforcement tools,” said Jeffrey Chester, the executive director of the Center for Digital Democracy, a nonprofit group in Washington. “We now have a way to hold these companies accountable.”
  • Privacy advocates and even some United States regulators have long been concerned about the ability of online services to track consumers and make inferences about their financial status, health concerns and other intimate details to show them behavior-based ads. They warned that such microtargeting could unfairly categorize or exclude certain people.
  • the Do Not Track effort and the privacy bill were both stymied.Industry groups successfully argued that collecting personal details posed no harm to consumers and that efforts to hinder data collection would chill innovation.
  • “If it can be shown that the current situation is actually a market failure and not an individual-company failure, then there’s a case to be made for federal regulation” under certain circumstances
  • The business practices of Facebook and Google were reinforced by the fact that no privacy flap lasted longer than a news cycle or two. Nor did people flee for other services. That convinced the companies that digital privacy was a dead issue.
  • If the current furor dies down without meaningful change, critics worry that the problems might become even more entrenched. When the tech industry follows its natural impulses, it becomes even less transparent.
  • “To know the real interaction between populism and Facebook, you need to give much more access to researchers, not less,” said Paul-Jasper Dittrich, a German research fellow
  • There’s another reason Silicon Valley tends to be reluctant to share information about what it is doing. It believes so deeply in itself that it does not even think there is a need for discussion. The technology world’s remedy for any problem is always more technology
Javier E

There's No Such Thing As 'Sound Science' | FiveThirtyEight - 1 views

fivethirtyeight.com/...d-science-demand-sound-science

science method research trade-off values fact objectivity

shared by Javier E on 10 Dec 17 - No Cached
  • cience is being turned against itself. For decades, its twin ideals of transparency and rigor have been weaponized by those who disagree with results produced by the scientific method. Under the Trump administration, that fight has ramped up again.
  • The same entreaties crop up again and again: We need to root out conflicts. We need more precise evidence. What makes these arguments so powerful is that they sound quite similar to the points raised by proponents of a very different call for change that’s coming from within science.
  • Despite having dissimilar goals, the two forces espouse principles that look surprisingly alike: Science needs to be transparent. Results and methods should be openly shared so that outside researchers can independently reproduce and validate them. The methods used to collect and analyze data should be rigorous and clear, and conclusions must be supported by evidence.
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  • they’re also used as talking points by politicians who are working to make it more difficult for the EPA and other federal agencies to use science in their regulatory decision-making, under the guise of basing policy on “sound science.” Science’s virtues are being wielded against it.
  • What distinguishes the two calls for transparency is intent: Whereas the “open science” movement aims to make science more reliable, reproducible and robust, proponents of “sound science” have historically worked to amplify uncertainty, create doubt and undermine scientific discoveries that threaten their interests.
  • “Our criticisms are founded in a confidence in science,” said Steven Goodman, co-director of the Meta-Research Innovation Center at Stanford and a proponent of open science. “That’s a fundamental difference — we’re critiquing science to make it better. Others are critiquing it to devalue the approach itself.”
  • alls to base public policy on “sound science” seem unassailable if you don’t know the term’s history. The phrase was adopted by the tobacco industry in the 1990s to counteract mounting evidence linking secondhand smoke to cancer.
  • The sound science tactic exploits a fundamental feature of the scientific process: Science does not produce absolute certainty. Contrary to how it’s sometimes represented to the public, science is not a magic wand that turns everything it touches to truth. Instead, it’s a process of uncertainty reduction, much like a game of 20 Questions.
  • Any given study can rarely answer more than one question at a time, and each study usually raises a bunch of new questions in the process of answering old ones. “Science is a process rather than an answer,” said psychologist Alison Ledgerwood of the University of California, Davis. Every answer is provisional and subject to change in the face of new evidence. It’s not entirely correct to say that “this study proves this fact,” Ledgerwood said. “We should be talking instead about how science increases or decreases our confidence in something.”
  • While insisting that they merely wanted to ensure that public policy was based on sound science, tobacco companies defined the term in a way that ensured that no science could ever be sound enough. The only sound science was certain science, which is an impossible standard to achieve.
  • “Doubt is our product,” wrote one employee of the Brown & Williamson tobacco company in a 1969 internal memo. The note went on to say that doubt “is the best means of competing with the ‘body of fact’” and “establishing a controversy.” These strategies for undermining inconvenient science were so effective that they’ve served as a sort of playbook for industry interests ever since
  • Doubt merchants aren’t pushing for knowledge, they’re practicing what Proctor has dubbed “agnogenesis” — the intentional manufacture of ignorance. This ignorance isn’t simply the absence of knowing something; it’s a lack of comprehension deliberately created by agents who don’t want you to know,
  • In the hands of doubt-makers, transparency becomes a rhetorical move. “It’s really difficult as a scientist or policy maker to make a stand against transparency and openness, because well, who would be against it?
  • But at the same time, “you can couch everything in the language of transparency and it becomes a powerful weapon.” For instance, when the EPA was preparing to set new limits on particulate pollution in the 1990s, industry groups pushed back against the research and demanded access to primary data (including records that researchers had promised participants would remain confidential) and a reanalysis of the evidence. Their calls succeeded and a new analysis was performed. The reanalysis essentially confirmed the original conclusions, but the process of conducting it delayed the implementation of regulations and cost researchers time and money.
  • Delay is a time-tested strategy. “Gridlock is the greatest friend a global warming skeptic has,” said Marc Morano, a prominent critic of global warming research
  • which has received funding from the oil and gas industry. “We’re the negative force. We’re just trying to stop stuff.”
  • these ploys are getting a fresh boost from Congress. The Data Quality Act (also known as the Information Quality Act) was reportedly written by an industry lobbyist and quietly passed as part of an appropriations bill in 2000. The rule mandates that federal agencies ensure the “quality, objectivity, utility, and integrity of information” that they disseminate, though it does little to define what these terms mean. The law also provides a mechanism for citizens and groups to challenge information that they deem inaccurate, including science that they disagree with. “It was passed in this very quiet way with no explicit debate about it — that should tell you a lot about the real goals,” Levy said.
  • in the 20 months following its implementation, the act was repeatedly used by industry groups to push back against proposed regulations and bog down the decision-making process. Instead of deploying transparency as a fundamental principle that applies to all science, these interests have used transparency as a weapon to attack very particular findings that they would like to eradicate.
  • Now Congress is considering another way to legislate how science is used. The Honest Act, a bill sponsored by Rep. Lamar Smith of Texas,3The bill has been passed by the House but still awaits a vote in the Senate. is another example of what Levy calls a “Trojan horse” law that uses the language of transparency as a cover to achieve other political goals. Smith’s legislation would severely limit the kind of evidence the EPA could use for decision-making. Only studies whose raw data and computer codes were publicly available would be allowed for consideration.
  • It might seem like an easy task to sort good science from bad, but in reality it’s not so simple. “There’s a misplaced idea that we can definitively distinguish the good from the not-good science, but it’s all a matter of degree,” said Brian Nosek, executive director of the Center for Open Science. “There is no perfect study.” Requiring regulators to wait until they have (nonexistent) perfect evidence is essentially “a way of saying, ‘We don’t want to use evidence for our decision-making,’
  • ost scientific controversies aren’t about science at all, and once the sides are drawn, more data is unlikely to bring opponents into agreement.
  • objective knowledge is not enough to resolve environmental controversies. “While these controversies may appear on the surface to rest on disputed questions of fact, beneath often reside differing positions of value; values that can give shape to differing understandings of what ‘the facts’ are.” What’s needed in these cases isn’t more or better science, but mechanisms to bring those hidden values to the forefront of the discussion so that they can be debated transparently. “As long as we continue down this unabashedly naive road about what science is, and what it is capable of doing, we will continue to fail to reach any sort of meaningful consensus on these matters,”
  • The dispute over tobacco was never about the science of cigarettes’ link to cancer. It was about whether companies have the right to sell dangerous products and, if so, what obligations they have to the consumers who purchased them.
  • Similarly, the debate over climate change isn’t about whether our planet is heating, but about how much responsibility each country and person bears for stopping it
  • While researching her book “Merchants of Doubt,” science historian Naomi Oreskes found that some of the same people who were defending the tobacco industry as scientific experts were also receiving industry money to deny the role of human activity in global warming. What these issues had in common, she realized, was that they all involved the need for government action. “None of this is about the science. All of this is a political debate about the role of government,”
  • These controversies are really about values, not scientific facts, and acknowledging that would allow us to have more truthful and productive debates. What would that look like in practice? Instead of cherry-picking evidence to support a particular view (and insisting that the science points to a desired action), the various sides could lay out the values they are using to assess the evidence.
  • For instance, in Europe, many decisions are guided by the precautionary principle — a system that values caution in the face of uncertainty and says that when the risks are unclear, it should be up to industries to show that their products and processes are not harmful, rather than requiring the government to prove that they are harmful before they can be regulated. By contrast, U.S. agencies tend to wait for strong evidence of harm before issuing regulations
  • the difference between them comes down to priorities: Is it better to exercise caution at the risk of burdening companies and perhaps the economy, or is it more important to avoid potential economic downsides even if it means that sometimes a harmful product or industrial process goes unregulated?
  • But science can’t tell us how risky is too risky to allow products like cigarettes or potentially harmful pesticides to be sold — those are value judgements that only humans can make.
clairemann

What Long-Haulers Should Know About Getting The Coronavirus Vaccine | HuffPost Life - 1 views

www.huffpost.com/...ine_l_604f55b6c5b60e0725f91ed6

COVID pandemic research education technology

shared by clairemann on 27 Mar 21 - No Cached
  • Four months after her initial diagnosis, in October, Chason’s physician told her she was suffering from long COVID.
  • Four days after the first dose, Chason said, the symptoms — vertigo, nausea, loss of appetite, chills — hit like a lightning bolt. “I went through every single thing I had been dealing with since I had COVID,” Chason said.
  • Around the world, many other people with long-haul symptoms — a condition now clinically defined as post-acute sequelae of SARS-CoV-2, or PASC — have reported similar experiences after getting a vaccine.
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  • COVID-19 survivors, found that 36% of people with long-haul symptoms noticed improvements in their condition after vaccination. About 50% remained the same. Other unofficial surveys have also estimated that about a third of patients with long COVID feel better after getting a vaccine.
  • “We don’t know who gets PASC, who avoids it, what exactly is causing it, or how to even diagnose it effectively,” said William Li, a vascular biologist and medical director of the Angiogenesis Foundation. Without those answers, it’s difficult to clearly see how the vaccines impact long-haulers, for better or worse.
knudsenlu

The Brutal Math of Gender Inequality in Hollywood - The Atlantic - 0 views

www.theatlantic.com/...550232

gender inequality hollywood culture

shared by knudsenlu on 13 Jan 18 - No Cached
  • Lady Bird won the award for Best Motion Picture Musical or Comedy, but its writer and director Greta Gerwig was curiously not nominated for Best Director. That category’s five nominees were all male. In fact, only one woman has ever won a Golden Globe for directing: Barbra Streisand, in 1984, for Yentl. At the time, Gerwig was six months old, and her film’s lead actress had not yet been born. Hollywood remains an industry where women are more likely to be celebrated for speaking out in front of a camera than for holding one.
  • Finally, actresses are vulnerable, not only because men dominate powerful occupations, but also because women are cast to portray the very quality of vulnerability
  • Altogether, these surveys and studies suggest something quite simple: The ratio of women in an industry (like film) or in an occupation within that industry (like directing) shapes how women are treated. While more than 80 percent of women say they have been harassed at work, they are 50 percent more likely to say so in male-dominated industries.
katherineharron

In race for coronavirus vaccine, hurled insults and the wisdom of Spider-Man - CNN - 0 views

www.cnn.com/...index.html

shared by katherineharron on 27 May 20 - No Cached
  • Ethicists and physicians are concerned that, amid a desire to put an end to the Covid-19 pandemic, developers of drugs and vaccines have become overly enthusiastic about the chances their products will work.
  • Oxford has recently walked back some of its optimism, but for months, it set a tone that its vaccine was the most promising, without any solid evidence that this was based in fact.
  • Third, one leader in the Oxford team has gone so far as to denigrate other teams trying to get a Covid vaccine on the market, calling their technology "weird" and labeling it as merely "noise." Such name-calling is highly unusual and aggressive among scientists.
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  • "At this point, the Oxford researchers have no idea whether they have something or not," Offit said. "You just get so tired of this 'science by press release.' "
  • There are currently 10 vaccines in human clinical trials worldwide, according to the World Health Organization. Four of the teams are in the United States: Moderna, Pfizer, Inovio and Novavax.
  • Moderna CEO Stéphane Bancel referred to the results as "positive interim Phase 1 data" and that "the Moderna team continues to focus on moving as fast as safely possible to start our pivotal Phase 3 study in July."
  • Moderna is collaborating on its vaccine development with the National Institute of Allergy and Infectious Diseases. Dr. Anthony Fauci, the director of NIAID, said while Moderna's numbers were limited, "it was good news" and he was "cautiously optimistic" about the vaccine.
  • Inovio and Moderna have said they expect their large-scale clinical trials, known as Phase 3 trials, to last around six months. Pfizer hasn't given a timetable for its Phase 3 trial.
  • "I've not seen anyone wrap up a Phase 3 trial in a month to six weeks," said Dr. Saad Omer, a Yale University infectious disease expert who's done clinical trials on polio, pertussis and influenza vaccines. "We need to benchmark this against realistic expectations."
  • "As vaccine researchers like to say, mice lie and monkeys exaggerate," Offit said.
  • One big stumbling block for any vaccine trial is that Covid-19 infection rates in many areas of the world are flattening out or declining.
  • The Oxford vaccine uses what's called an adenovirus vector. Adenoviruses cause the common cold, but in this case, the adenoviruses are weakened and modified to deliver genetic material that codes for a protein from the novel coronavirus. The body then produces that protein and, ideally, develops an immune response to it.
  • "Compared to previous vaccines, this method is more robust, more versatile, and yet, equally efficient," according to the blog, which notes that the Bill & Melinda Gates Foundation invested $53 million in a German biotech company that specializes in RNA vaccines.
  • Inovio's technology uses a brief electrical pulse to deliver plasmids, or small pieces of genetic information, into human cells. Inovio says those cells then produce the vaccine, which leads to an immune response.
  • On April 19, the BBC's Andrew Marr said he asked Gilbert "if it's guaranteed that a workable vaccine can actually be produced."
  • "Nobody can be absolutely sure it's possible. That's why we have to do trials. We have to find out. I think the prospects are very good, but it's clearly not completely certain,"
  • "It certainly worked in monkeys," Oxford's Hill told CNN's Burnett May 15. "That was quite an impressive impact and that was our first try, if you like, with a standard dose, a single dose of vaccine."
  • "I buy that this is a pandemic and we may need to show progress and show steps, and I'm OK with making forecasts if decision makers want that, but do it with a level of uncertainty, because that's what's warranted," said Omer, director of the Yale Institute for Global Health.
  • "Now researchers can't wait to step out to the microphone -- and there are so many microphones out there -- to say, 'I've got it! This looks really good!' " Offit said.
blythewallick

Facial Recognition Moves Into a New Front: Schools - The New York Times - 0 views

www.nytimes.com/...acial-recognition-schools.html

research Technology education science

shared by blythewallick on 06 Feb 20 - No Cached
  • im Shultz tried everything he could think of to stop facial recognition technology from entering the public schools in Lockport, a small city 20 miles east of Niagara Falls. He posted about the issue in a Facebook group called Lockportians. He wrote an Op-Ed in The New York Times. He filed a petition with the superintendent of the district, where his daughter is in high school.But a few weeks ago, he lost. The Lockport City School District turned on the technology to monitor who’s on the property at its eight schools, becoming the first known public school district in New York to adopt facial recognition, and one of the first in the nation.
  • Proponents call it a crucial crime-fighting tool, to help prevent mass shootings and stop sexual predators. Robert LiPuma, the Lockport City School District’s director of technology, said he believed that if the technology had been in place at Marjory Stoneman Douglas High School in Parkland, Fla., the deadly 2018 attack there may never have happened.
  • “You had an expelled student that would have been put into the system, because they were not supposed to be on school grounds,” Mr. LiPuma said. “They snuck in through an open door. The minute they snuck in, the system would have identified that person.”
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  • “Subjecting 5-year-olds to this technology will not make anyone safer, and we can’t allow invasive surveillance to become the norm in our public spaces,” said Stefanie Coyle, deputy director of the Education Policy Center for the New York Civil Liberties Union.
  • When the system is on, Mr. LiPuma said, the software looks at the faces captured by the hundreds of cameras and calculates whether those faces match a “persons of interest” list made by school administrators.
  • Jayde McDonald, a political science major at Buffalo State College, grew up as one of the few black students in Lockport public schools. She said she thought it was too risky for the school to install a facial recognition system that could automatically call the police.
  • “I’m not sure where they are in the school or even think I’ve seen them,” said Brooke Cox, 14, a freshman at Lockport High School. “I don’t fully know why we have the cameras. I haven’t been told what their purpose is.”
  • “If suspended students are put on the watch list, they are going to be scrutinized more heavily,” he said, which could lead to a higher likelihood that they could enter into the criminal justice system.
  • Days after the district announced that the technology had been turned on, some students said they had been told very little about how it worked.
  • “We all want to keep our children safe in school,” she said. “But there are more effective, proven ways to do so that are less costly.”
Javier E

How the leading coronavirus vaccines made it to the finish line - The Washington Post - 0 views

www.washingtonpost.com/...covid-vaccine-messenger-rna

vaccine R&D science profit innovation discovery research

shared by Javier E on 06 Dec 20 - No Cached
  • If, as expected in the next few weeks, regulators give those vaccines the green light, the technology and the precision approach to vaccine design could turn out to be the pandemic’s silver linings: scientific breakthroughs that could begin to change the trajectory of the virus this winter and also pave the way for highly effective vaccines and treatments for other diseases.
  • Vaccine development typically takes years, even decades. The progress of the last 11 months shifts the paradigm for what’s possible, creating a new model for vaccine development and a toolset for a world that will have to fight more never-before-seen viruses in years to come.
  • Long before the pandemic, Graham worked with colleagues there and in academia to create a particularly accurate 3-D version of the spiky proteins that protrude from the surface of coronaviruses — an innovation that was rejected for publication by scientific journals five times because reviewers questioned its relevance.
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  • Messenger RNA is a powerful, if fickle, component of life’s building blocks — a workhorse of the cell that is also truly just a messenger, unstable and prone to degrade.
  • . In 1990,
  • That same year, a team at the University of Wisconsin startled the scientific world with a paper that showed it was possible to inject a snippet of messenger RNA into mice and turn their muscle cells into factories, creating proteins on demand.
  • If custom-designed RNA snippets could be used to turn cells into bespoke protein factories, messenger RNA could become a powerful medical tool. It could encode fragments of virus to teach the immune system to defend against pathogens. It could also create whole proteins that are missing or damaged in people with devastating genetic diseases, such as cystic fibrosis.
  • In 2005, the pair discovered a way to modify RNA, chemically tweaking one of the letters of its code, so it didn’t trigger an inflammatory response. Deborah Fuller, a scientist who works on RNA and DNA vaccines at the University of Washington, said that work deserves a Nobel Prize.
  • messenger RNA posed a bigger challenge than other targets.“It’s tougher — it’s a much bigger molecule, it’s much more unstable,”
  • Unlike fields that were sparked by a single powerful insight, Sahin said that the recent success of messenger RNA vaccines is a story of countless improvements that turned an alluring biological idea into a beneficial technology.
  • “This is a field which benefited from hundreds of inventions,” said Sahin, who noted that when he started BioNTech in 2008, he cautioned investors that the technology would not yield a product for at least a decade. He kept his word: Until the coronavirus sped things along, BioNTech projected the launch of its first commercial project in 2023.
  • “It’s new to you,” Fuller said. “But for basic researchers, it’s been long enough. . . . Even before covid, everyone was talking: RNA, RNA, RNA.”
  • All vaccines are based on the same underlying idea: training the immune system to block a virus. Old-fashioned vaccines do this work by injecting dead or weakened viruses
  • ewer vaccines use distinctive bits of the virus, such as proteins on their surface, to teach the lesson. The latest genetic techniques, like messenger RNA, don’t take as long to develop because those virus bits don’t have to be generated in a lab. Instead, the vaccine delivers a genetic code that instructs cells to build those characteristic proteins themselves.
  • They wanted the immune system to learn to recognize the thumb tack spike, so McLellan tasked a scientist in his laboratory with identifying genetic mutations that could anchor the protein into the right configuration. It was a painstaking process for Nianshuang Wang, who now works at a biotechnology company, Regeneron Pharmaceuticals. After trying hundreds of genetic mutations, he found two that worked. Five journals rejected the finding, questioning its significance, before it was published in 2017.
  • That infection opened Graham’s eyes to an opportunity. HKU1 was merely a nuisance, as opposed to a deadly pneumonia; that meant it would be easier to work with in the lab, since researchers wouldn’t have to don layers of protective gear and work in a pressurized laboratory.
  • Severe acute respiratory syndrome had emerged in 2003. Middle East respiratory syndrome (MERS) broke out in 2012. It seemed clear to Graham and Jason McLellan, a structural biologist now at the University of Texas at Austin, that new coronaviruses were jumping into people on a 10-year-clock and it might be time to brace for the next one.
  • Last winter, when Graham heard rumblings of a new coronavirus in China, he brought the team back together. Once its genome was shared online by Chinese scientists, the laboratories in Texas and Maryland designed a vaccine, utilizing the stabilizing mutations and the knowledge they had gained from years of basic research — a weekend project thanks to the dividends of all that past work.
  • Graham needed a technology that could deliver it into the body — and had already been working with Moderna, using its messenger RNA technology to create a vaccine against a different bat virus, Nipah, as a dress rehearsal for a real pandemic. Moderna and NIH set the Nipah project aside and decided to go forward with a coronavirus vaccine.
  • On Jan. 13, Moderna’s Moore came into work and found her team already busy translating the stabilized spike protein into their platform. The company could start making the vaccine almost right away because of its experience manufacturing experimental cancer vaccines, which involves taking tumor samples and developing personalized vaccines in 45 days.
  • At BioNTech, Sahin said that even in the early design phases of its vaccine candidates, he incorporated the slight genetic changes designed in Graham’s lab that would make the spike look more like the real thing. At least two other companies would incorporate that same spike.
  • If all goes well with regulators, the coronavirus vaccines have the makings of a pharmaceutical industry fairy tale. The world faced an unparalleled threat, and companies leaped into the fight. Pfizer plowed $2 billion into the effort. Massive infusions of government cash helped remove the financial risks for Moderna.
  • But the world will also owe their existence to many scientists outside those companies, in government and academia who pursued ideas they thought were important even when the world doubted them
  • Some of those scientists will receive remuneration, since their inventions are licensed and integrated into the products that could save the world.
  • As executives become billionaires, many scientists think it is fair to earn money from their inventions that can help them do more important work. But McLellan’s laboratory at the University of Texas is proud to have licensed an even more potent version of their spike protein, royalty-free, to be incorporated into a vaccine for low and middle income countries.
  • “They’re using the technology that [Kariko] and I developed,” he said. “We feel like it’s our vaccine, and we are incredibly excited — at how well it’s going, and how it’s going to be used to get rid of this pandemic.”
  • “People hear about [vaccine progress] and think someone just thought about it that night. The amount of work — it’s really a beautiful story of fundamental basic research,” Fauci said. “It was chancy, in the sense that [the vaccine technology] was new. We were aware there would be pushback. The proof in the pudding is a spectacular success.”
  • The Vaccine Research Center, where Graham is deputy director, was the brainchild of Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases. It was created in 1997 to bring together scientists and physicians from different disciplines to defeat diseases, with a heavy focus on HIV.
  • the pandemic wasn’t a sudden eureka moment — it was a catalyst that helped ignite lines of research that had been moving forward for years, far outside the spotlight of a global crisis.
Javier E

Pupils at elite Welsh school to get lessons in climate change - 0 views

www.thetimes.co.uk/...ange-curriculum-2023-rcdkd8mgx

IB curriculum global issues new climate change assessment innovation testing learning

shared by Javier E on 26 May 23 - No Cached
  • For the first time in 50 years, the directors of the IB are collaborating with schools to create an updated version of the qualification taken by 16 to 19-year-olds as an alternative to A-levels
  • A cohort of 20 pupils at UWC will drop a third of the traditional subjects usually studied within the IB. Instead they will spend 300 hours, over two years of study, on the new areas. Forms of assessment have yet to be finalised but there will be no exams on these subjects.
  • Learning will be project-based, collaborative and designed to tackle “multiple global crises” around the world. IB says it is creating the new qualification because there is a growing disconnect between the education children are receiving and the education they need.
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  • Olli-Pekka Heinonen, director-general of the IB, told The Times that teenagers taking the new diploma would be “uniquely empowered” on leaving school.
  • Traditional assessment often led to pupils forgetting what they had learnt once exams were over, he said. “The aim of this type of assessment is to strengthen deep learning and understanding, something you learn that stays with you and is part of you. We’re experimenting with non-exam assessment and finding the best ways to evaluate.
  • “Biodiversity, food, migration and energy are meaningful and attractive to young people. They’re appealing and relevant.“We’re looking at these areas through the lens of systems leadership — ie, how it’s possible to make change happen.”
  • The school hosts pupils from 80 different countries and charges fees of £37,000 a year. It is set in St Donat’s Castle, in 122 acres and its grounds include woodland, farmland, a valley and its own seafront.
  • Naheed Bardai, principal of UWC Atlantic, said he felt dissatisfied with the state of education in the world today as pupils should be prepared to become leaders of organisations and government in the 2040s and 2050s.
  • He said the new qualification would help them understand the root causes of problems but also become compassionate world leaders that can create “transformative solutions”.
  • “Our core policies are peace, sustainability and experiential learning but there’s very little education for young people at the intersection of problems, particularly where the human meets the natural world,”
  • We need people who can take constructive action as inequality is growing at a tremendous rate.”
  • Bardai said the school had been given a free hand in curriculum writing and was looking at more radical forms of assessment. This may include interviews, peer assessment and portfolios.
Javier E

Whistleblower: Twitter misled investors, FTC and underplayed spam issues - Washington Post - 0 views

www.washingtonpost.com/...twitter-whistleblower-sec-spam

twitter whistleblower security social media technology

shared by Javier E on 27 Aug 22 - No Cached
  • Twitter executives deceived federal regulators and the company’s own board of directors about “extreme, egregious deficiencies” in its defenses against hackers, as well as its meager efforts to fight spam, according to an explosive whistleblower complaint from its former security chief.
  • The complaint from former head of security Peiter Zatko, a widely admired hacker known as “Mudge,” depicts Twitter as a chaotic and rudderless company beset by infighting, unable to properly protect its 238 million daily users including government agencies, heads of state and other influential public figures.
  • Among the most serious accusations in the complaint, a copy of which was obtained by The Washington Post, is that Twitter violated the terms of an 11-year-old settlement with the Federal Trade Commission by falsely claiming that it had a solid security plan. Zatko’s complaint alleges he had warned colleagues that half the company’s servers were running out-of-date and vulnerable software and that executives withheld dire facts about the number of breaches and lack of protection for user data, instead presenting directors with rosy charts measuring unimportant changes.
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  • The complaint — filed last month with the Securities and Exchange Commission and the Department of Justice, as well as the FTC — says thousands of employees still had wide-ranging and poorly tracked internal access to core company software, a situation that for years had led to embarrassing hacks, including the commandeering of accounts held by such high-profile users as Elon Musk and former presidents Barack Obama and Donald Trump.
  • the whistleblower document alleges the company prioritized user growth over reducing spam, though unwanted content made the user experience worse. Executives stood to win individual bonuses of as much as $10 million tied to increases in daily users, the complaint asserts, and nothing explicitly for cutting spam.
  • Chief executive Parag Agrawal was “lying” when he tweeted in May that the company was “strongly incentivized to detect and remove as much spam as we possibly can,” the complaint alleges.
  • Zatko described his decision to go public as an extension of his previous work exposing flaws in specific pieces of software and broader systemic failings in cybersecurity. He was hired at Twitter by former CEO Jack Dorsey in late 2020 after a major hack of the company’s systems.
  • “I felt ethically bound. This is not a light step to take,” said Zatko, who was fired by Agrawal in January. He declined to discuss what happened at Twitter, except to stand by the formal complaint. Under SEC whistleblower rules, he is entitled to legal protection against retaliation, as well as potential monetary rewards.
  • “Security and privacy have long been top companywide priorities at Twitter,” said Twitter spokeswoman Rebecca Hahn. She said that Zatko’s allegations appeared to be “riddled with inaccuracies” and that Zatko “now appears to be opportunistically seeking to inflict harm on Twitter, its customers, and its shareholders.” Hahn said that Twitter fired Zatko after 15 months “for poor performance and leadership.” Attorneys for Zatko confirmed he was fired but denied it was for performance or leadership.
  • A person familiar with Zatko’s tenure said the company investigated Zatko’s security claims during his time there and concluded they were sensationalistic and without merit. Four people familiar with Twitter’s efforts to fight spam said the company deploys extensive manual and automated tools to both measure the extent of spam across the service and reduce it.
  • Overall, Zatko wrote in a February analysis for the company attached as an exhibit to the SEC complaint, “Twitter is grossly negligent in several areas of information security. If these problems are not corrected, regulators, media and users of the platform will be shocked when they inevitably learn about Twitter’s severe lack of security basics.”
  • Zatko’s complaint says strong security should have been much more important to Twitter, which holds vast amounts of sensitive personal data about users. Twitter has the email addresses and phone numbers of many public figures, as well as dissidents who communicate over the service at great personal risk.
  • This month, an ex-Twitter employee was convicted of using his position at the company to spy on Saudi dissidents and government critics, passing their information to a close aide of Crown Prince Mohammed bin Salman in exchange for cash and gifts.
  • Zatko’s complaint says he believed the Indian government had forced Twitter to put one of its agents on the payroll, with access to user data at a time of intense protests in the country. The complaint said supporting information for that claim has gone to the National Security Division of the Justice Department and the Senate Select Committee on Intelligence. Another person familiar with the matter agreed that the employee was probably an agent.
  • “Take a tech platform that collects massive amounts of user data, combine it with what appears to be an incredibly weak security infrastructure and infuse it with foreign state actors with an agenda, and you’ve got a recipe for disaster,” Charles E. Grassley (R-Iowa), the top Republican on the Senate Judiciary Committee,
  • Many government leaders and other trusted voices use Twitter to spread important messages quickly, so a hijacked account could drive panic or violence. In 2013, a captured Associated Press handle falsely tweeted about explosions at the White House, sending the Dow Jones industrial average briefly plunging more than 140 points.
  • After a teenager managed to hijack the verified accounts of Obama, then-candidate Joe Biden, Musk and others in 2020, Twitter’s chief executive at the time, Jack Dorsey, asked Zatko to join him, saying that he could help the world by fixing Twitter’s security and improving the public conversation, Zatko asserts in the complaint.
  • In 1998, Zatko had testified to Congress that the internet was so fragile that he and others could take it down with a half-hour of concentrated effort. He later served as the head of cyber grants at the Defense Advanced Research Projects Agency, the Pentagon innovation unit that had backed the internet’s invention.
  • But at Twitter Zatko encountered problems more widespread than he realized and leadership that didn’t act on his concerns, according to the complaint.
  • Twitter’s difficulties with weak security stretches back more than a decade before Zatko’s arrival at the company in November 2020. In a pair of 2009 incidents, hackers gained administrative control of the social network, allowing them to reset passwords and access user data. In the first, beginning around January of that year, hackers sent tweets from the accounts of high-profile users, including Fox News and Obama.
  • Several months later, a hacker was able to guess an employee’s administrative password after gaining access to similar passwords in their personal email account. That hacker was able to reset at least one user’s password and obtain private information about any Twitter user.
  • Twitter continued to suffer high-profile hacks and security violations, including in 2017, when a contract worker briefly took over Trump’s account, and in the 2020 hack, in which a Florida teen tricked Twitter employees and won access to verified accounts. Twitter then said it put additional safeguards in place.
  • This year, the Justice Department accused Twitter of asking users for their phone numbers in the name of increased security, then using the numbers for marketing. Twitter agreed to pay a $150 million fine for allegedly breaking the 2011 order, which barred the company from making misrepresentations about the security of personal data.
  • After Zatko joined the company, he found it had made little progress since the 2011 settlement, the complaint says. The complaint alleges that he was able to reduce the backlog of safety cases, including harassment and threats, from 1 million to 200,000, add staff and push to measure results.
  • But Zatko saw major gaps in what the company was doing to satisfy its obligations to the FTC, according to the complaint. In Zatko’s interpretation, according to the complaint, the 2011 order required Twitter to implement a Software Development Life Cycle program, a standard process for making sure new code is free of dangerous bugs. The complaint alleges that other employees had been telling the board and the FTC that they were making progress in rolling out that program to Twitter’s systems. But Zatko alleges that he discovered that it had been sent to only a tenth of the company’s projects, and even then treated as optional.
  • “If all of that is true, I don’t think there’s any doubt that there are order violations,” Vladeck, who is now a Georgetown Law professor, said in an interview. “It is possible that the kinds of problems that Twitter faced eleven years ago are still running through the company.”
  • The complaint also alleges that Zatko warned the board early in his tenure that overlapping outages in the company’s data centers could leave it unable to correctly restart its servers. That could have left the service down for months, or even have caused all of its data to be lost. That came close to happening in 2021, when an “impending catastrophic” crisis threatened the platform’s survival before engineers were able to save the day, the complaint says, without providing further details.
  • One current and one former employee recalled that incident, when failures at two Twitter data centers drove concerns that the service could have collapsed for an extended period. “I wondered if the company would exist in a few days,” one of them said.
  • The current and former employees also agreed with the complaint’s assertion that past reports to various privacy regulators were “misleading at best.”
  • For example, they said the company implied that it had destroyed all data on users who asked, but the material had spread so widely inside Twitter’s networks, it was impossible to know for sure
  • As the head of security, Zatko says he also was in charge of a division that investigated users’ complaints about accounts, which meant that he oversaw the removal of some bots, according to the complaint. Spam bots — computer programs that tweet automatically — have long vexed Twitter. Unlike its social media counterparts, Twitter allows users to program bots to be used on its service: For example, the Twitter account @big_ben_clock is programmed to tweet “Bong Bong Bong” every hour in time with Big Ben in London. Twitter also allows people to create accounts without using their real identities, making it harder for the company to distinguish between authentic, duplicate and automated accounts.
  • In the complaint, Zatko alleges he could not get a straight answer when he sought what he viewed as an important data point: the prevalence of spam and bots across all of Twitter, not just among monetizable users.
  • Zatko cites a “sensitive source” who said Twitter was afraid to determine that number because it “would harm the image and valuation of the company.” He says the company’s tools for detecting spam are far less robust than implied in various statements.
  • “Agrawal’s Tweets and Twitter’s previous blog posts misleadingly imply that Twitter employs proactive, sophisticated systems to measure and block spam bots,” the complaint says. “The reality: mostly outdated, unmonitored, simple scripts plus overworked, inefficient, understaffed, and reactive human teams.”
  • The four people familiar with Twitter’s spam and bot efforts said the engineering and integrity teams run software that samples thousands of tweets per day, and 100 accounts are sampled manually.
  • Some employees charged with executing the fight agreed that they had been short of staff. One said top executives showed “apathy” toward the issue.
  • Zatko’s complaint likewise depicts leadership dysfunction, starting with the CEO. Dorsey was largely absent during the pandemic, which made it hard for Zatko to get rulings on who should be in charge of what in areas of overlap and easier for rival executives to avoid collaborating, three current and former employees said.
  • For example, Zatko would encounter disinformation as part of his mandate to handle complaints, according to the complaint. To that end, he commissioned an outside report that found one of the disinformation teams had unfilled positions, yawning language deficiencies, and a lack of technical tools or the engineers to craft them. The authors said Twitter had no effective means of dealing with consistent spreaders of falsehoods.
  • Dorsey made little effort to integrate Zatko at the company, according to the three employees as well as two others familiar with the process who spoke on the condition of anonymity to describe sensitive dynamics. In 12 months, Zatko could manage only six one-on-one calls, all less than 30 minutes, with his direct boss Dorsey, who also served as CEO of payments company Square, now known as Block, according to the complaint. Zatko allegedly did almost all of the talking, and Dorsey said perhaps 50 words in the entire year to him. “A couple dozen text messages” rounded out their electronic communication, the complaint alleges.
  • Faced with such inertia, Zatko asserts that he was unable to solve some of the most serious issues, according to the complaint.
  • Some 30 percent of company laptops blocked automatic software updates carrying security fixes, and thousands of laptops had complete copies of Twitter’s source code, making them a rich target for hackers, it alleges.
  • A successful hacker takeover of one of those machines would have been able to sabotage the product with relative ease, because the engineers pushed out changes without being forced to test them first in a simulated environment, current and former employees said.
  • “It’s near-incredible that for something of that scale there would not be a development test environment separate from production and there would not be a more controlled source-code management process,” said Tony Sager, former chief operating officer at the cyberdefense wing of the National Security Agency, the Information Assurance divisio
  • Sager is currently senior vice president at the nonprofit Center for Internet Security, where he leads a consensus effort to establish best security practices.
  • Zatko stopped the material from being presented at the Dec. 9, 2021 meeting, the complaint said. But over his continued objections, Agrawal let it go to the board’s smaller Risk Committee a week later.
  • “A best practice is that you should only be authorized to see and access what you need to do your job, and nothing else,” said former U.S. chief information security officer Gregory Touhill. “If half the company has access to and can make configuration changes to the production environment, that exposes the company and its customers to significant risk.”
  • The complaint says Dorsey never encouraged anyone to mislead the board about the shortcomings, but that others deliberately left out bad news.
  • The complaint says that about half of Twitter’s roughly 7,000 full-time employees had wide access to the company’s internal software and that access was not closely monitored, giving them the ability to tap into sensitive data and alter how the service worked. Three current and former employees agreed that these were issues.
  • An unnamed executive had prepared a presentation for the new CEO’s first full board meeting, according to the complaint. Zatko’s complaint calls the presentation deeply misleading.
  • The presentation showed that 92 percent of employee computers had security software installed — without mentioning that those installations determined that a third of the machines were insecure, according to the complaint.
  • Another graphic implied a downward trend in the number of people with overly broad access, based on the small subset of people who had access to the highest administrative powers, known internally as “God mode.” That number was in the hundreds. But the number of people with broad access to core systems, which Zatko had called out as a big problem after joining, had actually grown slightly and remained in the thousands.
  • The presentation included only a subset of serious intrusions or other security incidents, from a total Zatko estimated as one per week, and it said that the uncontrolled internal access to core systems was responsible for just 7 percent of incidents, when Zatko calculated the real proportion as 60 percent.
  • When Dorsey left in November 2021, a difficult situation worsened under Agrawal, who had been responsible for security decisions as chief technology officer before Zatko’s hiring, the complaint says.
  • Agrawal didn’t respond to requests for comment. In an email to employees after publication of this article, obtained by The Post, he said that privacy and security continues to be a top priority for the company, and he added that the narrative is “riddled with inconsistences” and “presented without important context.”
  • On Jan. 4, Zatko reported internally that the Risk Committee meeting might have been fraudulent, which triggered an Audit Committee investigation.
  • Agarwal fired him two weeks later. But Zatko complied with the company’s request to spell out his concerns in writing, even without access to his work email and documents, according to the complaint.
  • Since Zatko’s departure, Twitter has plunged further into chaos with Musk’s takeover, which the two parties agreed to in May. The stock price has fallen, many employees have quit, and Agrawal has dismissed executives and frozen big projects.
  • Zatko said he hoped that by bringing new scrutiny and accountability, he could improve the company from the outside.
  • “I still believe that this is a tremendous platform, and there is huge value and huge risk, and I hope that looking back at this, the world will be a better place, in part because of this.”
Javier E

Photo of Officer Giving Boots to Barefoot Man Warms Hearts All Over Web - NYTimes.com - 0 views

www.nytimes.com/...t-man-warms-hearts-online.html

morality exemplar police poverty

shared by Javier E on 30 Nov 12 - No Cached
  • On a cold November night in Times Square, Officer Lawrence DePrimo was working a counterterrorism post when he encountered an older, barefooted homeless man. The officer disappeared for a moment, then returned with a new pair of boots, and knelt to help the man put them on.
  • The officer, normally assigned to the Sixth Precinct in the West Village, readily recalled the encounter. “It was freezing out and you could see the blisters on the man’s feet,” he said in an interview. “I had two pairs of socks and I was still cold.” They started talking; he found out the man’s shoe size: 12.
  • As the man walked slowly down Seventh Avenue on his heels, Officer DePrimo went into a Skechers shoe store at about 9:30 p.m. “We were just kind of shocked,” said Jose Cano, 28, a manager working at the store that night. “Most of us are New Yorkers and we just kind of pass by that kind of thing. Especially in this neighborhood.”
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  • The photo was taken by Jennifer Foster, a civilian communications director for the Pinal County Sheriff’s Office in Arizona. She said the moment resonated for personal reasons: She remembered as a young girl seeing her father, a 32-year veteran of the Phoenix police force, buy food for a homeless man. “He squatted down, just like this officer,” she said.
Javier E

Doubts about Johns Hopkins research have gone unanswered, scientist says - The Washingt... - 0 views

www.washingtonpost.com/...2-82e8-61a46c2cde3d_print.html

science research fraud bias

shared by Javier E on 12 Mar 13 - No Cached
  • Over and over, Daniel Yuan, a medical doctor and statistician, couldn’t understand the results coming out of the lab, a prestigious facility at Johns Hopkins Medical School funded by millions from the National Institutes of Health.He raised questions with the lab’s director. He reran the calculations on his own. He looked askance at the articles arising from the research, which were published in distinguished journals. He told his colleagues: This doesn’t make sense.“At first, it was like, ‘Okay — but I don’t really see it,’ ” Yuan recalled. “Then it started to smell bad.”
  • The passions of scientific debate are probably not much different from those that drive achievement in other fields, so a tragic, even deadly dispute might not be surprising.But science, creeping ahead experiment by experiment, paper by paper, depends also on institutions investigating errors and correcting them if need be, especially if they are made in its most respected journals.If the apparent suicide and Yuan’s detailed complaints provoked second thoughts about the Nature paper, though, there were scant signs of it.The journal initially showed interest in publishing Yuan’s criticism and told him that a correction was “probably” going to be written, according to e-mail rec­ords. That was almost six months ago. The paper has not been corrected.The university had already fired Yuan in December 2011, after 10 years at the lab. He had been raising questions about the research for years. He was escorted from his desk by two security guards.
  • Last year, research published in the Proceedings of the National Academy of Sciences found that the percentage of scientific articles retracted because of fraud had increased tenfold since 1975. The same analysis reviewed more than 2,000 retracted biomedical papers and found that 67 percent of the retractions were attributable to misconduct, mainly fraud or suspected fraud.
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  • Fang said retractions may be rising because it is simply easier to cheat in an era of digital images, which can be easily manipulated. But he said the increase is caused at least in part by the growing competition for publication and for NIH grant money.He noted that in the 1960s, about two out of three NIH grant requests were funded; today, the success rate for applicants for research funding is about one in five. At the same time, getting work published in the most esteemed journals, such as Nature, has become a “fetish” for some scientists, Fang said.
  • many observers note that universities and journals, while sometimes agreeable to admitting small mistakes, are at times loath to reveal that the essence of published work was simply wrong.“The reader of scientific information is at the mercy of the scientific institution to investigate or not,” said Adam Marcus, who with Ivan Oransky founded the blog Retraction Watch in 2010. In this case, Marcus said, “if Hopkins doesn’t want to move, we may not find out what is happening for two or three years.”
  • The trouble is that a delayed response — or none at all — leaves other scientists to build upon shaky work. Fang said he has talked to researchers who have lost months by relying on results that proved impossible to reproduce.Moreover, as Marcus and Oransky have noted, much of the research is funded by taxpayers. Yet when retractions are done, they are done quietly and “live in obscurity,” meaning taxpayers are unlikely to find out that their money may have been wasted.
Javier E

Computer Algorithms Rely Increasingly on Human Helpers - NYTimes.com - 0 views

www.nytimes.com/...easingly-on-human-helpers.html

algorithms computer google search relevance human

shared by Javier E on 13 Mar 13 - No Cached
  • Although algorithms are growing ever more powerful, fast and precise, the computers themselves are literal-minded, and context and nuance often elude them. Capable as these machines are, they are not always up to deciphering the ambiguity of human language and the mystery of reasoning.
  • And so, while programming experts still write the step-by-step instructions of computer code, additional people are needed to make more subtle contributions as the work the computers do has become more involved. People evaluate, edit or correct an algorithm’s work. Or they assemble online databases of knowledge and check and verify them — creating, essentially, a crib sheet the computer can call on for a quick answer. Humans can interpret and tweak information in ways that are understandable to both computers and other humans.
  • Even at Google, where algorithms and engineers reign supreme in the company’s business and culture, the human contribution to search results is increasing. Google uses human helpers in two ways. Several months ago, it began presenting summaries of information on the right side of a search page when a user typed in the name of a well-known person or place, like “Barack Obama” or “New York City.” These summaries draw from databases of knowledge like Wikipedia, the C.I.A. World Factbook and Freebase, whose parent company, Metaweb, Google acquired in 2010. These databases are edited by humans.
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  • When Google’s algorithm detects a search term for which this distilled information is available, the search engine is trained to go fetch it rather than merely present links to Web pages. “There has been a shift in our thinking,” said Scott Huffman, an engineering director in charge of search quality at Google. “A part of our resources are now more human curated.”
  • “Our engineers evolve the algorithm, and humans help us see if a suggested change is really an improvement,” Mr. Huffman said.
  • Ben Taylor, 25, is a product manager at FindTheBest, a fast-growing start-up in Santa Barbara, Calif. The company calls itself a “comparison engine” for finding and comparing more than 100 topics and products, from universities to nursing homes, smartphones to dog breeds. Its Web site went up in 2010, and the company now has 60 full-time employees. Mr. Taylor helps design and edit the site’s education pages. He is not an engineer, but an English major who has become a self-taught expert in the arcane data found in Education Department studies and elsewhere. His research methods include talking to and e-mailing educators. He is an information sleuth.
Javier E

Michael Bloomberg: 6 ways to stop gun madness - 0 views

www.usatoday.com/...1777889

gun control policy US

shared by Javier E on 20 Dec 12 - No Cached
  • For more than a decade, both parties in Washington have mostly looked the other way when mass shootings occur. And they have mostly ignored the 34 victims who are murdered with guns every single day.
  • prohibit the manufacture and sale of the military-style assault weapons and high-capacity ammunition clips that have been used in too many mass shootings, including in Newtown. The previous ban on assault weapons expired in 2004. While President George W. Bush supported reinstating it, Congress never acted. The time has plainly come.
  • fix the broken background check system. Currently, nearly half of all gun sales in the U.S. are conducted without a background check. Criminals, the mentally ill, minors and domestic abusers are all prohibited from purchasing guns, but they all can do so as easily as attending a gun show or going online.
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  • fill the vacancy at the top of the Bureau of Alcohol, Tobacco, Firearms, and Explosives (ATF), which has been without a director for six years.
  • make gun trafficking a felony. Gun rights advocates agree that penalties for illegal use and possession of guns should be stiffened -- and so should penalties on those who are engaged in gun trafficking.
  • requires the federal government to compel states to submit all necessary records on felons, domestic abusers, the seriously mentally ill and others to the background check system.
  • step up its prosecution of gun criminals who try to buy guns. In 2009, 71,000 people who had been convicted of gun crimes tried to buy guns by lying on their background checks. Yet the federal government prosecuted only 77 of those cases.
  • crack down on rogue gun dealers.
  • . If President Obama and Congress fail to lead, 48,000 Americans will be killed with guns over the next four years.
Emily Horwitz

¿Por qué tosemos más en los conciertos de música clásica? - BBC Mundo - Noticias - 0 views

www.bbc.co.uk/...os_concierto_clasica_gtg.shtml

coughing classical music

shared by Emily Horwitz on 01 Feb 13 - No Cached
  • Todo está en silencio. Los instrumentos de cuerda, los de viento y percusión esperan la señal del director para empezar la pieza. Al otro lado está el público callado, tragando más espeso y conteniendo la tos. Hay alguien que no lo puede evitar y con el primer acorde empieza a toser. ¿Por qué siempre ocurre esto?
  • "Toda la estadística existente sugiere que la gente tose dos veces más durante los conciertos", le dijo Wagener a la BBC.
  • El especialista descubrió que la acción de toser no es completamente aleatoria. La pieza que se escucha también incita a toser más o menos.
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  • "Si se trata de conciertos más modernos, como por ejemplo música clásica del siglo XX, los movimientos más lentos y los silencios son interrumpidos con mayor frecuencia".
  • cuando alguien empieza a toser y contagia a los otros.
  • "Creo que muchas personas cuando van a conciertos clásicos se dan cuenta que el nivel de ruido es mucho menor que la música a la que están acostumbradas a oir a través de sus auriculares o conciertos de música pop", agregó la pianista.
  • ese silencio en los conciertos acústicos es reconfortante, para otros puede originar inconformidad que se manifiesta en la acción de toser.
  • Andreas Wagener se mostró parcialmente de acuerdo con la teoría de Tomes, pues "cuando alguien va a un concierto (de música clásica) sabe que debe permanecer en silencio".
  • "Es una cuestión de etiqueta, saben que no deben hablar o caminar, hacer ruido o toser, pero la gente sigue tosiendo en exceso".
  • con la tos no se puede saber si es deliberado o involuntario.
  • "Creo que a veces la gente no esta consciente de como suena para el concertista. Es un factor muy distractor".
  • Emily Horwitz on 01 Feb 13
     
    I realize that this article is in Spanish, so those who don't understand the language will likely be confused, but I thought that it was very interesting, and related to TOK. Essentially, the article talked about a study that Andreas Wagener, a German scientist did, in which it was discovered that people cough twice as much at classical music concerts than otherwise. Wagener also found that the amount of coughing was not random; rather, it was dependent on the style, tempo, etc. of the music being played. The slow, more modern pieces often elicited more coughs. Additionally, Wagener found that, similar to how we think about yawning, coughing is contagious; one cough can cause an avalanche of other coughs. The article also noted the possibility that some of the coughing going on during a classical music concert may not be the typical, involuntary, reflexive cough, but a deliberate cough of social interaction. In terms of TOK, I thought that this article was most interesting in that, when put into a situation in which we may be uncomfortable (often with silence), we cough more. I related this to my own experiences at Friends, during MFW, when people often seem to cough out of a need for interaction. It would be interesting to see if Wagener could work with some geneticists and biologists to discover if a connection between slow classical music and more coughing is purely biological, or if it stems from another causation of human behavior.
Emily Horwitz

News from The Associated Press - 0 views

hosted.ap.org/...US_OSCARS_FACT_OR_FICTION

historical movies truth fiction

shared by Emily Horwitz on 20 Feb 13 - No Cached
  • If you saw the film "Argo," no, you didn't miss this development, which is recounted in Mendez's book about the real-life operation. It wasn't there because director Ben Affleck and screenwriter Chris Terrio replaced it with an even more dramatic scenario, involving canceled flight reservations, suspicious Iranian officials who call the Hollywood office of the fake film crew (a call answered just in time), and finally a heart-pounding chase on the tarmac just as the plane's wheels lift off, seconds from catastrophe.
  • they've caught some flak for the liberties they took in the name of entertainment.
  • And they aren't alone - two other high-profile best-picture nominees this year, Kathryn Bigelow's "Zero Dark Thirty" and Steven Spielberg's "Lincoln," have also been criticized for different sorts of factual issues.
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  • But because these three major films are in contention, the issue has come to the forefront of this year's Oscar race, and with it a thorny cultural question: Does the audience deserve the truth, the whole truth and nothing but? Surely not, but just how much fiction is OK?
  • In response to a complaint by a Connecticut congressman, Kushner acknowledged he'd changed the details for dramatic effect, having two Connecticut congressmen vote against the amendment when, in fact, all four voted for it. (The names of those congressmen were changed, to avoid changing the vote of specific individuals.)
  • Kushner said he had "adhered to time-honored and completely legitimate standards for the creation of historical drama, which is what `Lincoln' is. I hope nobody is shocked to learn that I also made up dialogue and imagined encounters and invented characters."
  • "Maybe changing the vote went too far," says Richard Walter, chairman of screenwriting at the University of California, Los Angeles. "Maybe there was another way to do it. But really, it's not terribly important. People accept that liberties will be taken. A movie is a movie. People going for a history lesson are going to the wrong place."
  • Walter says he always tells his students: "Go for the feelings. Because the only thing that's truly real in the movies are the feelings that people feel when they watch."
  • No subject or individual's life is compelling and dramatic enough by itself, he says, that it neatly fits into a script with three acts, subplots, plot twists and a powerful villain.
  • Reeves, who actually gave the "Lincoln" script a negative review because he thought it was too heavy on conversation and lacking action. He adds, though, that when the subject is as famous as Lincoln, one has a responsibility to be more faithful to the facts.
  • "This is fraught territory," he says. "You're always going to have to change something, and you're always going to get in some sort of trouble, with somebody," he says.
  • Futterman also doesn't begrudge the "Argo" filmmakers, because he feels they use a directorial style that implies some fun is being had with the story. "All the inside joking about Hollywood - tonally, you get a sense that something is being played with," he says.
  • Futterman says he was sympathetic to those concerns and would certainly have addressed them in the script, had he anticipated them.
  • Of the three Oscar-nominated films in question, "Zero Dark Thirty" has inspired the most fervent debate. The most intense criticism, despite acclaim for the filmmaking craft involved, has been about its depictions of interrogations, with some, including a group of senators, saying the film misleads viewers for suggesting that torture provided information that helped the CIA find Osama bin Laden.
  • have been questions about the accuracy of the depiction of the main character, a CIA officer played by Jessica Chastain; the real person - or even combination of people, according to some theories - that she plays remains anonymous.
  • screenwriters have a double responsibility: to the material and to the audience.
  • The debate over "Argo" has been much less intense, though there has been some grumbling from former officials in Britain and New Zealand that their countries were portrayed incorrectly in the film as offering no help at all to the six Americans, whereas actually, as Mendez writes, they did provide some help.
  • "When I am hungry and crave a tuna fish sandwich, I don't go to a hardware store," he says. "When I seek a history lesson, I do not go to a movie theater. I loved `Argo' even though I know there was no last-minute turn-around via a phone call from President Carter, nor were there Iranian police cars chasing the plane down the tarmac as it took off. So what? These conceits simply make the movie more exciting."
  • Emily Horwitz on 20 Feb 13
     
    This article reaffirmed my feelings that we can't trust everything that we see or hear through the media, because it is often skewed to better captivate the target audience. As the article stated, there appears to be a fine line in catering to the attention span of the audience, and respecting the known facts of a given event that is portrayed by a movie.
proudsa

CDC Director Calls It 'Shameful' This Curable Disease Still Kills Millions - 0 views

www.huffingtonpost.com/...fight_568ecb4ee4b0a2b6fb6f5349

shared by proudsa on 08 Jan 16 - No Cached
  • "Drug-resistant tuberculosis threatens to reverse the gains that we've made. It's not just the threat overseas, it's the threat here,"
  • Drug-resistant tuberculosis knows no borders, and we risk turning the clock back on antibiotics and making it very difficult for us to stop tuberculosis from spreading around the world and in this country if we don't improve our control efforts.
  • We do prioritize addressing MDR-TB. We have done that for more than 20 years; that's why we've been able to drastically reduce U.S. cases of MDR-TB.
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  • How will you and the CDC help ensure a well-executed program?
  • Right, and one of the things that will help tuberculosis control is the test and treat approach, and increasing the proportion of HIV-positive people that are treated. The majority of TB cases currently occur before people are started on anti-HIV medicines.
  • Partly it's the characteristic of the bacteria: You require long-term treatment for many months, we don't have a vaccine as we do with measles or polio, but partly it's the nature of the control program.
  • Fundamentally, what happens with tuberculosis will depend on two things. First, how well we implement what we know today, and second, how quickly we get better tools to stop tuberculosis.
  • If we could figure out which of them are going to develop active TB and provide shorter, more effective treatments for them, then we might really be able to knock down tuberculosis cases.
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