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Nathan Goodyear

Comparison between effects of myo-inosito... [Gynecol Endocrinol. 2013] - PubMed - NCBI - 0 views

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    Myo-inositol and D-chiro-inositol improve metabolic function in women with PCOS.  Myo-inositol appears to have better effects on metabolic profile and D-chiro-inositol on reduced androgen effects.
Nathan Goodyear

D-chiro-inositol metabolism in diabetes mellitus - 0 views

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    d-chiro-inositol levels shown to be low in diabetics.  Thus, d-chiro-inositol would prove to be helpful in diabetes management.  D-chiro-inositol is a secondary messenger in insulin signaling
Nathan Goodyear

The Combined therapy myo-inositol ... [Eur Rev Med Pharmacol Sci. 2013] - PubMed - NCBI - 0 views

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    Combination therapy of d-chiro-inositol and myo-inositol improve metabolic markers of PCOS.
Nathan Goodyear

Randomized, double blind placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS. | Mendeley - 0 views

  • significant weight loss (and leptin reduction) (P < 0.01) was recorded in the myo-inositol group, whereas the placebo group actually increased weight
  • hese data support a beneficial effect of myo-inositol in women with oligomenorrhea and polycystic ovaries in improving ovarian function.
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    myo-inositol improves weight loss and leptin resistance through insulin secondary messenger
Nathan Goodyear

Effects of myo-inositol supplementation in postmen... [Menopause. 2011] - PubMed result - 0 views

  • Myo-inositol plus diet improved systolic and diastolic blood pressure, HOMA index, cholesterol, and triglyceride serum levels with highly significant differences,
  • Supplementation with myo-inositol may be considered a reliable option in the treatment of metabolic syndrome in postmenopausal women
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    myo-inositol proven to be a good treatment for those postmenopausal women with metabolic syndrome
Nathan Goodyear

Controlled trials of inositol in psychiatry. [Eur Neuropsychopharmacol. 1997] - PubMed result - 0 views

  • second messenger system important in the brain
  • Cerebrospinal fluid inositol has been reported as decreased in depression
  • hese results suggest that inositol has therapeutic effects in the spectrum of illness responsive to serotonin selective re-uptake inhibitors, including depression, panic and OCD, and is not beneficial in schizophrenia, Alzheimer's ADDH, autism or ECT-induced cognitive impairment.
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    brief discussion on biochemistry of inositol and its benefits in depression, panic, and OCD disorders
Nathan Goodyear

Endocrine and clinical effects of myo-ino... [Gynecol Endocrinol. 2013] - PubMed - NCBI - 0 views

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    Myo-inositol improves PCOS.  Specifically, myo-inositol improved insulin sensitivity, reduced insulin levels and restored HPA function.  IN these women with amenorrhea and oligomenorrhea, menestrual cycle regularity was restored.
Nathan Goodyear

Metabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: a double-blind trial - EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES - 0 views

  • Treatment of PCOS patients with Myo-inositol provided a decreasing of circulating insulin and serum total testosterone as well as an improvement in metabolic factors.
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    Myo-inositol shown to improve insulin resistance and lower testosterone levels in women with PCOS
Nathan Goodyear

Effect of inositol on bulimia nervosa and binge ea... [Int J Eat Disord. 2001] - PubMed result - 0 views

  • Inositol is as therapeutic in patients with bulimia nervosa and binge eating as it is in patients with depression and panic and obsessive-compulsive disorders
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    inositol effective in eating disorders, including binge eating
Nathan Goodyear

Inositol treatment of obsessive-compulsive disorde... [Am J Psychiatry. 1996] - PubMed result - 0 views

  • he authors conclude that inositol is effective in depression, panic, and obsessive-compulsive disorder
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    inositol effective in depression, panic, and obsessive-compulsive disorders
Nathan Goodyear

Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder -- Benjamin et al. 152 (7): 1084 -- Am J Psychiatry - 0 views

  • The authors conclude that inositol's efficacy, the absence of significant side effects, and the fact that inositol is a natural component of the human diet make it a potentially attractive therapeutic for panic disorder.
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    inositol proven effective in panic disorders
Nathan Goodyear

Cell - Insulin Signaling: Inositol Phosphates Get into the Akt - 0 views

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    Inositol phsophoglycans part of insulin signaling pathways
Nathan Goodyear

Role of inositolphosphoglycan mediators of insulin... [J Pediatr Endocrinol Metab. 2000] - PubMed result - 0 views

  • some actions of insulin are mediated by putative inositolphosphoglycan (IPG) mediators
  • known as second messengers
  • echanism by which insulin can stimulate ovarian androgen production even in women with PCOS
  • ...3 more annotations...
  • a deficiency in a specific D-chiro-inositol-containing IPG may contribute to insulin resistance in women with PCOS
  • IPG signaling system transduces insulin's stimulation of human thecal androgen biosynthesis
  • administration of D-chiro-inositol has been demonstrated to improve glucose tolerance, decrease serum androgens and improve ovulation in PCOS
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    D-chiro-inositol deficiency and its role in PCOS, insulin resistance, and hyperandrogenism
Nathan Goodyear

Effects of d-chiro-inositol in lean women with the... [Endocr Pract. 2002 Nov-Dec] - PubMed result - 0 views

  • women with the polycystic ovary syndrome, D-chiro-inositol reduces circulating insulin, decreases serum androgens, and ameliorates some of the metabolic abnormalities (increased blood pressure and hypertriglyceridemia) of syndrome X.
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    D-chiro-inositol reduced insulin levels and associated male hormone production in lean women with PCOS
Nathan Goodyear

Double-blind, controlled trial of inositol treatme... [Am J Psychiatry. 1995] - PubMed result - 0 views

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    inositol shows use in depression
Nathan Goodyear

Ovulatory and metabolic effects of D-chiro-inosito... [N Engl J Med. 1999] - PubMed result - 0 views

  • Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome, thereby improving ovulatory function and decreasing serum androgen concentrations, blood pressure, and plasma triglyceride concentrations.
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    Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome
Nathan Goodyear

D-chiro-inositol glycans in insulin signaling and ... [Mol Med. 2010 Nov-Dec] - PubMed result - 0 views

  • The metabolism of DCI is associated with insulin sensitivity and resistance, supporting the concept that second messengers have a role in responses to and resistance to insulin.
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    D-chiro-inositol is a secondary messenger in the insulin signaling pathway
Nathan Goodyear

Altered D-Chiro-Inositol Urinary Clearance in Women With Polycystic Ovary Syndrome - 0 views

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    low D-chiro-inositol contributes to insulin resistance and thus role in PCOS
Nathan Goodyear

Insulin-stimulated release of D-chiro-inositol-co... [Metabolism. 2008] - PubMed - NCBI - 0 views

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    D-chiro-inositol release correlated with improved insulin sensitivity.
Nathan Goodyear

D-Chiro-Inositol - Its Functional Role in Insulin Action and its Deficit in Insulin Resistance - 0 views

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    d-chiro-inositol improves insulin sensitivity and thus reduces insulin resistance
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